Abstract:
:Allergic granulomatosis and angiitis was first reported as a disease entity separate from polyarteritis nodosa in 1951 by Churg and Strauss. It is characterized by bronchial asthma, eosinophilia, and vasculitis and is especially rare in women of reproductive age, though, when present, may be associated with fetal mortality in pregnancy. We report a successful pregnancy in a patient who previously experienced intrauterine fetal death at 30 weeks of gestation.
journal_name
Int Arch Allergy Immunoljournal_title
International archives of allergy and immunologyauthors
Ogasawara M,Kajiura S,Inagaki H,Sasa H,Aoki K,Yagami Ydoi
10.1159/000237140subject
Has Abstractpub_date
1995-10-01 00:00:00pages
200-2issue
2eissn
1018-2438issn
1423-0097journal_volume
108pub_type
杂志文章abstract::The modulatory role of hormones in the regulation of the immune response has been well documented. Here, we present some thoughts on how sex hormones affect immunity, particularly at mucosal sites. We further discuss the possible pitfalls and difficulties associated with analysis of the data. ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章,评审
doi:10.1159/000236631
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Atopic dermatitis (AD) is increasing among the elderly. Staphylococcus aureus colonization is one of the most important aggravating factors in AD. OBJECTIVE:This study analyses the clinical features of AD in elderly patients and determines the pathogenic roles of staphylococcal superantigens in AD with low ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000329150
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Human leukocyte antigen G (HLA-G) is a nonclassical major histocompatibility complex class I gene. HLA-G stimulates Th2 cytokine secretion by peripheral blood mononuclear cells. The role of soluble HLA-G (sHLA-G) in bronchial asthma is incompletely understood and the plasma level of sHLA-G in asthmatic child...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000095290
更新日期:2006-01-01 00:00:00
abstract::The present study has extended histochemical and functional investigations into rat mast cell heterogeneity using isolated mast cells from four connective tissue locations; the peritoneum, mesentery, lung and skin. On histological examination, mast cells from these locations displayed a range of phenotypes following f...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000236161
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Dietary intake of wheat causes hypersensitivity reactions in patients suffering from IgE-mediated food allergy and coeliac disease. AIM:To study the expression of IgE- and IgA-reactive antigens during wheat seed maturation and in different wheat cultivars. METHODS:Summer wheat was grown in a glasshouse and...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000199713
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Severe refractory atopic dermatitis (AD) is a chronic, debilitating condition that is associated with elevated serum immunoglobulin E (IgE) levels. Thymic stromal lymphopoietin (TSLP), thymus and activation-regulated chemokine (TARC) and OX40 ligand (OX40L) are important immunologic factors involved in the p...
journal_title:International archives of allergy and immunology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000350486
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:In patients showing multiple reactivity to seasonal airborne allergens, a skin prick test (SPT) with Parietaria pollen scores frequently negative, suggesting that profilin from Parietaria might not share IgE-binding epitopes with profilin from botanically unrelated airborne allergens. This study investigated...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000076384
更新日期:2004-02-01 00:00:00
abstract::Guinea pigs were sensitized with 2,4-toluene diisocyanate (TDI) by a repetitive application onto the bilateral nasal vestibules once a day for 5 consecutive days. When these animals were further treated with TDI for additional 9 weeks, a number of these animals exhibited external symptoms similar to those in human ast...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000236504
更新日期:1993-01-01 00:00:00
abstract::In the last 40 years, the pathogenesis of transmissible spongiform encephalopathies of humans and animals have been the subject of exciting discoveries and also of passionate controversies. Although the human forms of these diseases are rare, the recent epidemics of bovine spongiform encephalopathy has most dramatical...
journal_title:International archives of allergy and immunology
pub_type: 历史文章,杂志文章,评审
doi:10.1159/000237273
更新日期:1996-06-01 00:00:00
abstract::Because of the importance of cytokines in the regulation of allergic inflammation, we investigated the effects of SCF, IL-3, IL-5 and GM-CSF on immunological histamine release from sensitized human lung fragments as well as human leukocytes. SCF (0.2-20 ng/ml) caused a concentration-related enhancement of anti-IgE (1/...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000236798
更新日期:1994-09-01 00:00:00
abstract::Eosinophils participate in the inflammatory response seen in allergy and helminthic infestation. Their release of granule-bound cationic proteins may play a role in these diseases. Therefore, we investigated mechanisms involved in the release of eosinophil cationic protein (ECP). Serum-opsonized zymosan was phagocytos...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000023891
更新日期:1998-02-01 00:00:00
abstract::A quantitative determination of the inflammatory mediators was performed and correlated with complaints and the measurement of the inflammatory cells in nasal secretions of 18 seasonal allergic rhinitis patients (group 1) outside the pollen season and 40 symptomatic patients (group 2) with seasonal allergic rhinitis d...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000236855
更新日期:1995-03-01 00:00:00
abstract::Mast cells are recognized not only as the major effector cells of type I hypersensitivity reactions but also as an important player of innate immune response against bacterial infection. Type I IFNs are also involved in the response against bacterial infection. However, the role of type I IFNs and their associated Jan...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000077789
更新日期:2004-06-01 00:00:00
abstract::Chlorhexidine is a commonly used antiseptic and disinfectant in the health-care setting. Its usage has increased in recent years with intensive campaigns and infection control guidelines to combat hospital-acquired infections. As a result, patients and health-care workers (HCW) are exposed to increasing chlorhexidine ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000431358
更新日期:2015-01-01 00:00:00
abstract::We report a clinical study comparing the skin test reactivity to recombinant Aspergillus fumigatus allergen 1 (rAsp fI/a) in patients with atopic dermatitis and A. fumigatus sensitisation (n = 15), A. fumigatus-allergic patients with asthma (n = 10) and healthy control subjects (n = 10). All patients sensitised to A. ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000237123
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND:Docosahexaenoic acid (DHA) found in fish oil is known to depress inflammation-related mediators. We investigated a novel delivery method of tridocosahexaenoyl-glycerol (DHA-TG). METHODS:BALB/c mice (6-8 weeks old) were primed intraperitoneally with ovalbumin (OVA) and Al(OH)(3) on days 0 and 7, and with aer...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000053645
更新日期:2000-12-01 00:00:00
abstract::Nitric oxide (NO) is a potent biological mediator, and has a regulatory role in a wide variety of cellular and tissue functions. In the upper and lower airways, NO has been suggested to be involved in different functions with regulatory, protective, defensive or damaging effects. It is obvious that NO plays an importa...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章,评审
doi:10.1159/000324678
更新日期:2011-01-01 00:00:00
abstract::The relationship between the IgE load on mast cells and their secretory capacity when challenged with anti-IgE was studied in peritoneal cells obtained from rats of three different strains, Hooded Lister (HL), Wistar Kyoto (WKY) and Sprague-Dawley (SD). IgE was determined cytofluorometrically after labelling with FITC...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000236849
更新日期:1995-03-01 00:00:00
abstract::Increased serum IgE and enhanced susceptibility to viral infections, decreased levels of interferons, lymphocytic skin infiltrates and IgE-bearing epidermal Langerhans cells are striking features in patients with atopic eczema (AE). Since the hyper-IgE syndrome is known to improve under alpha-interferon (alpha-IFN) th...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000236494
更新日期:1993-01-01 00:00:00
abstract::Peritoneal eosinophilia was induced in rats using Ascaris suum extract as an antigen, and characteristics of granule proteins of eosinophils collected from the peritoneal cavity were investigated. Peritoneal eosinophilia was induced by injection of the antigen solution into the peritoneal cavity of the immunized rats ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000237111
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND:The digestive system of Dermatophagoides farinae remains poorly documented. METHODS:In this study, a three-dimensional (3-D) model of the alimentary canal of D. farinae was built for the first time based on hematoxylin-eosin staining, 76 cross-sections of the adult mite and 3-D reconstruction technology. R...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000115890
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:The high-affinity IgE receptor, FcepsilonRI, is unresponsive on mast cells and basophils from people in several populations through an unknown mechanism. Similarly, FcepsilonRI-positive basophils from 'nonreleasers' are IgE-unresponsive and are deficient in the tyrosine kinase Syk. OBJECTIVE:To test the hyp...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000087355
更新日期:2005-09-01 00:00:00
abstract:UNLABELLED:T-bet is crucially implicated in Th1 differentiation due to its strong promoting activity for IFN-gamma gene transcription. However, the regulatory role of T-bet in Th2 cytokines is not fully delineated. METHODS:The effect of T-bet on mRNA expression as well as the promoter activity of IL-4 in human T cells...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000101408
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Common variable immunodeficiency (CVID) is characterized by hypogammaglobulinemia and a defect in antibody production. Herein we describe 3 patients diagnosed with CVID in whom vitamin D deficiency was detected in the absence of enteropathy. METHODS:Biochemical and immunological analysis, serum osteocalcin,...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000128661
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Interleukin (IL)-33, a new member of the IL-1 cytokine family, has been recognized as a key cytokine that enhances T helper 2-balanced immune regulation through its receptor ST2; however, the function and relationship of the IL-33 and ST2 pathways in bronchial asthma are still unclear. We investigated the ce...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000327259
更新日期:2011-01-01 00:00:00
abstract::To determine whether the costimulatory signal via CD28/B7 interaction is required for causing allergic inflammation, we examined the effect of administration of CTLA4-Ig, a fusion protein of the extracellular domain of CTLA4 and human IgG1-constant region, at the time of sensitization, on antigen-induced eosinophil in...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000053564
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:Depression and smoking contribute to the prognosis of autoimmune rheumatoid arthritis (RA). Advanced glycation end products (AGEs) are also detected in RA patients. This study correlates RA in patients with various levels of depression and a history of smoking through the detection of antibodies against AGEs...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000489896
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Atopic dermatitis (AD) and food allergy (FA) are common childhood diseases, which may either be interrelated or be the result of skin barrier disruption and gut mucosal dysbiosis. Although some evidence suggests the efficacy of emollients and synbiotics, there is no conclusive evidence on the use of these in...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000501636
更新日期:2019-01-01 00:00:00
abstract::Allergens from the pollen of Parthenium hysterophorus (American feverfew), responsible for high incidence of allergic rhinitis, were found by immunoprint analysis to be localized on the surface of the pollen grains. The allergens were released very rapidly when extracted in vitro. The allergenic activity of the rapid ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000237099
更新日期:1995-08-01 00:00:00
abstract::Factors are discussed as potential diagnostic parameters of atopic disorders. The amounts of sCD23 in sera from newborn children (n = 4,329) were determined by radioimmunoassay with monoclonal antibodies specific for CD23. The sCD23 levels ranged between 0 and 81.5 ng/ml of CD23-specific mAb. Furthermore, the sera of ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000236346
更新日期:1992-01-01 00:00:00