The potential allergenicity of two 2S albumins from soybean (Glycine max): a protein microarray approach.

abstract：:It is unclear what actually induces eosinophil degranulation in vivo. We examined eosinophil cationic protein (ECP) release from normal human eosinophils (Eos) in response to C3a and C5a. C3a and C5a induced remarkable ECP release when Eos were preincubated with cytochalasin B. ECP release induced by C3a or C5a was gr...

journal_title：International archives of allergy and immunology

authors： Takafuji S,Tadokoro K,Ito K,Dahinden CA

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:High osmolal ionic radiocontrast media (RCM) cause vascular release of endothelin-1 (ET-1) and activate mast cells. Iomeprol, a nonionic RCM, has recently been reported not to activate cardiac mast cells. This coronary angiography study was performed to extend those findings using another nonionic RCM, iopro...

journal_title：International archives of allergy and immunology

authors： Simon MR,Reher RL,Long PM,Yellayi K

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:15-Deoxy-Delta(12,14)-prostaglandin J2 (15d-PGJ2), a major prostanoid metabolized from prostaglandin D2 (PGD2), plays an important role in various biological processes including inflammatory responses. 15d-PGJ2 exerts its effects through two major receptors, chemoattractant receptor- homologous molecule expr...

journal_title：International archives of allergy and immunology

authors： Chiba T,Ueki S,Ito W,Kato H,Takeda M,Kayaba H,Furue M,Chihara J

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to evaluate the effectiveness of specific immunotherapy (SIT) management with allergoids in children with allergic asthma by monitoring changes in clinical parameters and inflammatory markers in exhaled breath. METHODS:The study population included 43 patients (24 males) of 6-14 ...

journal_title：International archives of allergy and immunology

authors： Lozano J,Cruz MJ,Piquer M,Giner MT,Plaza AM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Reports on oral immunotherapy (OIT) for anaphylactic food allergy are lacking. We investigated the efficacy and safety of peanut OIT for anaphylactic patients. METHODS:We enrolled 22 peanut anaphylactic patients who underwent OIT between 2011 and 2013, all of whom demonstrated anaphylaxis during a baseline ...

journal_title：International archives of allergy and immunology

authors： Nagakura KI,Sato S,Yanagida N,Nishino M,Asaumi T,Ogura K,Ebisawa M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Nasal polyps are a common health problem that can significantly impact the quality of life. OBJECTIVE:To analyze the impact of allergy and peripheral eosinophils (EOS) on the morbidity of chronic rhinosinusitis with nasal polyps (CRSwNP) in Northwest China. METHODS:A retrospective cohort of 323 patients wh...

journal_title：International archives of allergy and immunology

authors： Chen F,Wen L,Qiao L,Shi Z,Xue T,Chen X,Li X

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Diagnosis and immunotherapy of house-dust mite (HDM) allergy is still based on natural allergen extracts. The aim of this study was to analyze commercially available Dermatophagoides pteronyssinus extracts from different manufacturers regarding allergen composition and content and whether variations may affe...

journal_title：International archives of allergy and immunology

authors： Casset A,Mari A,Purohit A,Resch Y,Weghofer M,Ferrara R,Thomas WR,Alessandri C,Chen KW,de Blay F,Valenta R,Vrtala S

更新日期：2012-01-01 00:00:00

abstract：:Anti-cyclic citrullinated peptide antibodies (anti-CCP) are a new diagnostic marker for rheumatoid arthritis (RA), which shows a specificity of 97% and a sensitivity of 81% in the second generation assay. About 61% of RA patients express HLA-DRB1*0401. In a cohort of patients with RA we investigated whether the expres...

journal_title：International archives of allergy and immunology

authors： Senkpiehl I,Marget M,Wedler M,Jenisch S,Georgi J,Kabelitz D,Steinmann J

更新日期：2005-08-01 00:00:00

abstract：:Superoxide (O2-) and nitric oxide (NO) production by polymorphonuclear leukocyte (PMNs) and monocytes in patients with liver cirrhosis were evaluated. PMNs obtained from cirrhotic patients were less effective than those from controls in producing O2- after stimulation with opsonized zymosan, while they were more effec...

journal_title：International archives of allergy and immunology

authors： Masini E,Mugnai L,Foschi M,Laffi G,Gentilini P,Mannaioni PF

更新日期：1995-05-01 00:00:00

abstract：:A 73-year-old man developed organized pneumonia with severe right-sided eosinophilic pleural effusion (PE). CD69+ and HLA-DR+ eosinophils in PE were 90 and 31%, respectively, but were undetectable in peripheral blood (PB). CD4+, CD45RA+ (naive) and CD4+, CD45RO+ (memory) cells in PB, PE and bronchoalveolar lavage (BAL...

journal_title：International archives of allergy and immunology

authors： Hossain M,Okubo Y,Yamaguchi S,Horie S,Itoh S,Sugii S,Takatsu K,Oguchi T,Sekiguchi M

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Jellyfish stings cause painful, papular-urticarial eruptions due to the immediate allergic, acute toxic and persistent inflammatory responses. In spite of many marine accidents and their economic impact, modes of first-aid treatment remain conventional and specific allergen and medical treatment are not yet ...

journal_title：International archives of allergy and immunology

authors： Horiike T,Nagai H,Kitani S

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) is an acute, systemic vasculitis in children, with an etiology that is not completely understood. It is assumed that the development of KD is mediated by an immunologic response. Several reports from East Asia have found a higher prevalence of atopic diseases among patients with KD, but...

journal_title：International archives of allergy and immunology

authors： Hassidim A,Merdler I,Chorin O,Merdler-Rabinowicz R,Dallal I,Perlman M,Chorin E

更新日期：2016-01-01 00:00:00

abstract：:The aim of this study was to investigate whether repeated exposure to subclinical doses of cat allergens, not inducing asthma symptoms, could affect eosinophil cationic protein (ECP) levels in bronchoalveolar lavage (BAL) or in peripheral blood, without the appearance of clinical symptoms. Twelve patients with mild as...

journal_title：International archives of allergy and immunology

authors： de Blay F,Krieger P,Spirlet F,Moreau L,Duvernelle C,Kassel O,Kopferschmitt MC,Gasser B,Demangeat C,Pauli G,Frossard N

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Accumulating evidence indicates that eotaxin is the primary mediator of tissue eosinophilia. In the present study, we analyzed the mechanisms of eotaxin generation by Th1-/Th2-derived cytokines in vitro. METHODS:Human dermal fibroblasts, human umbilical vein endothelial cells and A549 human bronchial epithe...

journal_title：International archives of allergy and immunology

authors： Miyamasu M,Misaki Y,Yamaguchi M,Yamamoto K,Morita Y,Matsushima K,Nakajima T,Hirai K

更新日期：2000-05-01 00:00:00

abstract：:Olive pollen is one of the most important causes of seasonal respiratory allergy in Mediterranean countries, where this tree is intensely cultivated. Among the high number of protein allergens detected in this pollen, 8 - Ole e 1 to Ole e 8 - have been isolated and characterized. Ole e 1 is the most frequent sensitizi...

journal_title：International archives of allergy and immunology

authors： Rodríguez R,Villalba M,Monsalve RI,Batanero E

更新日期：2001-07-01 00:00:00

abstract：:Oral immunotherapy (OIT) is a significant focus of treatment of food allergy. OIT appears to be effective in inducing desensitization, however, patients receiving OIT frequently developmild/moderate symptoms during the therapy. It has not been clearly established whether the clinical tolerance induced by OIT resembles...

journal_title：International archives of allergy and immunology

authors： Sato S,Yanagida N,Ogura K,Imai T,Utsunomiya T,Iikura K,Goto M,Asaumi T,Okada Y,Koike Y,Syukuya A,Ebisawa M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:It has been shown that antigen presentation by resting B cells can induce tolerance to intravenously administered protein antigens, but the role of resting B cells in the induction of oral tolerance is unclear. METHODS:Mice continuously treated since birth with rabbit anti-mouse IgM serum for 5 weeks were d...

journal_title：International archives of allergy and immunology

authors： Peng HJ,Chang ZN,Kuo SW,Lee CC,Tzau YY

更新日期：2000-07-01 00:00:00

abstract：:Antibody response after immunization with surface-coupled ovalbumin (OVA) of liposomes was investigated in mice. OVA was coupled to the surface of liposome via amino groups using glutaraldehyde. OVA-liposome conjugate induced a significant anti-OVA IgG antibody production in mice. However, no IgE antibody production s...

journal_title：International archives of allergy and immunology

authors： Naito S,Horino A,Nakayama M,Nakano Y,Nagai T,Mizuguchi J,Komuro K,Uchida T

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Allergic reactions occur rarely in patients with chronic helminth infections, although FcepsilonRI-bearing cells are sensitized with anti-parasite IgE and are exposed to antigen. The inhibition of allergic reactivity is due to 'blocking antibodies', predominantly IgG4. IgG4 antibodies represent 50-95% of ant...

journal_title：International archives of allergy and immunology

authors： Agresti A,Vercelli D

更新日期：1999-02-01 00:00:00

abstract：:Human mononuclear leukocytes (MNL), probably OKT4-positive T cells, produced an eosinophil chemotactic factor (ECF) when they were cocultured with irradiated BALL-1, a B cell lymphoma line. Treatment of MNL, with anti-IL-2 antibody failed to suppress BALL-1-induced ECF production. Periodate-lysine-paraformaldehyde-fix...

journal_title：International archives of allergy and immunology

authors： Yoshida N,Ueno M,Saita N,Hirashima M

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Mercury causes in mouse strains of the H-2s haplotype an autoimmune syndrome with antibodies to the nucleolar protein fibrillarin and systemic immune complex (IC) deposits. Other strains, like BALB/C (H-2d), develop only IC deposits, and most strains are resistant. However, mercury activates the murine immun...

journal_title：International archives of allergy and immunology

authors： Johansson U,Hansson-Georgiadis H,Hultman P

更新日期：1998-08-01 00:00:00

abstract：:The objective of this study was to investigate the role of progesterone in modulating electrophysiological responses to antigenic challenge that are reflective of immune functions in uterine and jejunal mucosae. In the rat-Trichinella spiralis, host-parasite system, an enteric infection with a microscopic nematode sen...

journal_title：International archives of allergy and immunology

authors： Harari Y,Castro GA

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Staphylococcus aureus-producing superantigens (SAgs), such as staphylococcal enterotoxin B (SEB) or toxic shock syndrome toxin-1 (TSST-1), are frequently observed in atopic dermatitis (AD). However, little has been done to establish the association of immune responses to SAgs and the therapeutic response to ...

journal_title：International archives of allergy and immunology

authors： Fukushima H,Hirano T,Shibayama N,Miwa K,Ito T,Saito M,Sumida H,Oyake S,Tsuboi R,Oka K

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Exposure and sensitization to indoor allergens have been associated with the development of asthma and other allergic diseases in many parts of the world. It is important to establish the degree of exposure, and to evaluate whether allergen control measures are effective in a particular area. METHODS:Concen...

journal_title：International archives of allergy and immunology

authors： Tobias KR,Ferriani VP,Chapman MD,Arruda LK

更新日期：2004-04-01 00:00:00

abstract：:Corticosteroid-resistant (CR) asthma is associated with disease chronicity, a more frequent family history of asthma and impaired in vitro and in vivo responsiveness of peripheral blood mononuclear cells to the suppressive effects of glucocorticoids. CR asthma is associated with normal suppression of the hypothalamic-...

journal_title：International archives of allergy and immunology

authors： Lane SJ,Lee TH

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Nuclear factor (NF)-kappaB is a transcription factor known to regulate allergy-associated cytokine and chemokine production related to the induction of inflammation. I kappaB kinase beta (IKK beta), which is responsible for activation of the NF-kappaB pathway, may be an ideal molecular target to inhibit this...

journal_title：International archives of allergy and immunology

authors： Sugita A,Ogawa H,Azuma M,Muto S,Honjo A,Yanagawa H,Nishioka Y,Tani K,Itai A,Sone S

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Pre-clinical and clinical studies have evaluated the efficacy of probiotics in allergy. However, predictive in vitro systems for rational strain selection are still missing. METHODS:We developed a novel in vitro screening system for the characterization of probiotics with anti-allergic potential. In this mo...

journal_title：International archives of allergy and immunology

authors： Holvoet S,Zuercher AW,Julien-Javaux F,Perrot M,Mercenier A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Recent studies have demonstrated that eosinophils from allergic patients express low levels of FcepsilonRI on their surface, but the regulatory mechanisms of eosinophil surface FcepsilonRI expression are not fully understood. We investigated whether IL-4 and IgE, which are reported to regulate surface Fcepsi...

journal_title：International archives of allergy and immunology

authors： Iikura M,Yamaguchi M,Hirai K,Miyamasu M,Yamada H,Nakajima T,Fujisawa T,Ra C,Morita Y,Yamamoto K

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Exposure to Aspergillus fumigatus allergens results in the sensitization and the development of allergic bronchopulmonary aspergillosis in susceptible individuals. Aspergillus antigen consists of a number of chemically diverse components and their cumulative or synergistic effect may result in disease. When ...

journal_title：International archives of allergy and immunology

authors： Kurup VP,Xia JQ,Shen HD,Rickaby DA,Henderson JD Jr,Fink JN,Chou H,Kelly KJ,Dawson CA

更新日期：2002-10-01 00:00:00

abstract：:Accumulation and activation of eosinophils in tissue are critical events in the allergic inflammatory response and adhesion molecules play important roles in this process. We previously demonstrated that human eosinophils expressed a nuclear receptor, peroxisome proliferator-activated receptor gamma (PPARgamma), and t...

journal_title：International archives of allergy and immunology

authors： Hirasawa H,Chiba T,Ueki S,Kamada Y,Ito W,Takeda M,Fujita M,Kato H,Kayaba H,Chihara J

更新日期：2008-01-01 00:00:00