Resting B cells are not antigen-presenting cells in the induction of oral tolerance of specific Th2 immune responses in mice.

abstract：BACKGROUND:There is no information whether galectin-9 (a novel eosinophil chemoattractant) was associated with pathogenesis of eosinophilic disorders. METHODS:We assessed the expression of galectin-9 with imunostaining and in situ hybridization both in the lesion of angiolymphoid hyperplasia with eosinophilia, and per...

journal_title：International archives of allergy and immunology

authors： Saita N,Goto E,Yamamoto T,Cho I,Tsumori K,Kohrogi H,Maruo K,Ono T,Takeya M,Kashio Y,Nakamura K,Hirashima M

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DC) play a decisive role in the induction of allergen-induced Th1 and Th2 responses. Since the induction of allergen-specific Th1 responses has shown to inhibit allergen-induced Th2-type inflammation, in this study we investigated whether manipulated myeloid-derived DC pulsed with the specif...

journal_title：International archives of allergy and immunology

authors： Trujillo-Vargas CM,Ramirez-Pineda JR,Palmetshofer A,Grunewald S,Moll H,Berberich C,Erb KJ

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The precise roles of T helper (Th)1-type and Th2-type cytokine responses in nickel (Ni)-induced allergic contact dermatitis have not yet been clearly defined. We investigated the involvement of Th2 cytokines in Ni-induced contact hypersensitivity reaction using GATA-3 transgenic (Tg) mice. METHODS:A Ni-tita...

journal_title：International archives of allergy and immunology

authors： Niiyama S,Tamauchi H,Amoh Y,Terashima M,Matsumura Y,Kanoh M,Habu S,Komotori J,Katsuoka K

更新日期：2010-01-01 00:00:00

abstract：:Eosinophils are pleiotropic multi-functional leukocytes involved in initiation and propagation of diverse inflammatory responses. Recent studies examining eosinophil biology have focused on delineating the molecular basis of FIP1L1/PDGRFalpha-fusion gene induced HES, the molecular steps involved in eosinophil recruitm...

journal_title：International archives of allergy and immunology

authors： Hogan SP

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Previous studies have indicated that colitis increases intestinal permeability to food antigens. This condition also generates an immunoreactive milieu in the gut, which may exacerbate or counteract allergy reactions. This, along with the fact that both colitis and allergy are being codiagnosed more frequent...

journal_title：International archives of allergy and immunology

authors： Cueto-Sola M,Bailon E,Utrilla P,Rodríguez-Ruiz J,Garrido-Mesa N,Zarzuelo A,Xaus J,Gálvez J,Comalada M

更新日期：2013-01-01 00:00:00

abstract：:Antibodies to rat Thy-1, and also to murine Thy-1, could provoke reverse passive cutaneous anaphylaxis-like (RPCA-like) reactions. The threshold amount of purified anti-Thy-1 antibodies for RPCA-like reactions was 12.5 microg/ml. No RPCA-like reactions were obtained with IgG1 F(ab')2 anti-Thy-1. Cross-linking the muri...

journal_title：International archives of allergy and immunology

authors： Yamaji C,Hirano T,Miyajima H,Hashimoto H,Okumura K,Ovary Z

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Dietary intake of wheat causes hypersensitivity reactions in patients suffering from IgE-mediated food allergy and coeliac disease. AIM:To study the expression of IgE- and IgA-reactive antigens during wheat seed maturation and in different wheat cultivars. METHODS:Summer wheat was grown in a glasshouse and...

journal_title：International archives of allergy and immunology

authors： Constantin C,Touraev A,Heberle-Bors E,Quirce S,Huber WD,Valenta R

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Immunoglobulin G4-related disease (IgG4-RD) is a systemic immunological disorder characterized by fibro-inflammatory conditions; however, the pathobiology of IgG4-RD has not been fully identified. OBJECTIVE:This study aimed to analyze systemic differences of innate and adaptive immune cells from healthy con...

journal_title：International archives of allergy and immunology

authors： Sohn KH,Ham J,Chung SJ,Kang HR,Kim HY

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The aetiology of chronic urticaria is heterogeneous. Physical urticaria (PU) is estimated at around 35%, autoimmune urticaria (AIU) at 25% and chronic idiopathic urticaria (CIU) at 35% of all chronic urticaria cases. METHODS:Differences in clinical and laboratory parameters among AIU, PU and CIU groups were...

journal_title：International archives of allergy and immunology

authors： Irinyi B,Széles G,Gyimesi E,Tumpek J,Herédi E,Dimitrios G,Adány R,Hunyadi J,Szegedi A

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Pseudomonas aeruginosa phospholipase C (PLC) is a critical component in the pathogenesis of severe P. aeruginosa infections. However, P. aeruginosa can produce a hemolytic (PLC-H) as well as a nonhemolytic (PLC-N) variant, both having a MW of about 77 kD. In the past, studies did not distinguish between both...

journal_title：International archives of allergy and immunology

authors： König B,Vasil ML,König W

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Clustered severe adverse reactions to immunotherapy with olive pollen extracts have been occasionally reported in areas where olive trees are extensively grown. Allergic patients from these areas, in addition to the major olive pollen allergen Ole e 1, frequently recognize a recently described allergen, Ole ...

journal_title：International archives of allergy and immunology

authors： Duffort O,Palomares O,Lombardero M,Villalba M,Barber D,Rodríguez R,Polo F

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:In some subjects, specific foods trigger anaphylaxis when exercise follows ingestion (specific food-dependent exercise-induced anaphylaxis, FDEIAn). Skin test and/or RAST positivity to foods suggest an IgE-mediated pathogenic mechanism. Others suffer from anaphylaxis after all meals followed by exercise, reg...

journal_title：International archives of allergy and immunology

authors： Romano A,Di Fonso M,Giuffreda F,Papa G,Artesani MC,Viola M,Venuti A,Palmieri V,Zeppilli P

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Asthma, allergic conditions, and COPD overlap, but the effect of them and their combinations on disease severity, need for drugs, use of healthcare, and costs is poorly known. OBJECTIVE:To study how different allergic diseases co-occur in asthma and allergy patients and evaluate the use of medication well a...

journal_title：International archives of allergy and immunology

authors： Jantunen J,Haahtela T,Salimäki J,Linna M,Mäkelä M,Pelkonen A,Kauppi P

更新日期：2019-01-01 00:00:00

abstract：:We investigated the in vitro adhesion of 51Cr-labeled lymphocytes to cultured brain endothelial cells and the in vivo expression of intercellular adhesion molecule-1 (ICAM-1) on cerebral endothelial cells in a rat model of experimental allergic encephalomyelitis (EAE) before and after treatment with lipopolysaccharide...

journal_title：International archives of allergy and immunology

authors： Matsuda M,Tsukada N,Miyagi K,Yanagisawa N

更新日期：1995-04-01 00:00:00

abstract：:CD95 (APO-1) is a member of the TNF/nerve growth factor receptor superfamily, which is expressed on the surface of different types of cells. Cross-linking of CD95 leads to the induction of apoptosis. This may be of importance in many physiological systems, but seems to play a special role for the maintenance of immuno...

journal_title：International archives of allergy and immunology

authors： Lechner H,Amort M,Steger MM,Maczek C,Grubeck-Loebenstein B

更新日期：1996-07-01 00:00:00

abstract：:Contact sensitivity to para-phenylenediamine (PPD) is a frequent delayed-type hypersensitivity resulting in contact dermatitis. The aim of the present study, conducted in 16 patients allergic to PPD (as assessed by a positive patch test), was to get better insight into the mechanism of T-cell activation in PPD contact...

journal_title：International archives of allergy and immunology

authors： Krasteva M,Nicolas JF,Chabeau G,Garrigue JL,Bour H,Thivolet J,Schmitt D

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:alpha-Melanocyte-stimulating hormone (alpha-MSH) is a neuropeptide that controls melanogenesis in pigmentary cells. In addition, its potent immunomodulatory activity has been recently described in cutaneous inflammatory disorders. However the mechanism of such pollen allergies remains to be elucidated. The p...

journal_title：International archives of allergy and immunology

authors： Hiramoto K,Hashimoto M,Orita K,Jikumaru M,Sato EF,Inoue M

更新日期：2010-01-01 00:00:00

abstract：:The case of a 46-year-old man with a chronic cough with sputum eosinophilia (atopic cough) caused by Trichosporon cutaneum serotype II (Trichosporon asahii) is reported. The diagnosis was made with the inhalation challenge test with T. asahii antigen. He was admitted for the diagnosis and treatment of a severe nonprod...

journal_title：International archives of allergy and immunology

authors： Ogawa H,Fujimura M,Amaike S,Nishiura Y,Nakagawa-Yoshida K,Suga M,Ando M,Matsuda T

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:High antibiotic prescribing rates for adults with an asthma exacerbation have been reported in developed countries, but few studies have assessed the variation of antibiotic and adjunctive treatment in the routine care of children. OBJECTIVE:We evaluated the trends in health resource utilization for childre...

journal_title：International archives of allergy and immunology

authors： Okubo Y,Horimukai K,Michihata N,Morita K,Matsui H,Fushimi K,Yasunaga H

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Shellfish allergy is one of the major causes of life-threatening allergic reactions to food. The shrimp species Pandalus borealis is the commercially most important coldwater shrimp species, and its protein extract is commonly used in shrimp allergy diagnostics. However, the DNA sequence of its major allerge...

journal_title：International archives of allergy and immunology

authors： Myrset HR,Barletta B,Di Felice G,Egaas E,Dooper MM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Protective acquired immunity against helminths and allergic sensitisation are both characterised by high IgE antibody levels. Levels of IgE antibodies are naturally tightly regulated by several mechanisms including binding of the CD23 receptor. Following observations that helminth infections and allergic sen...

journal_title：International archives of allergy and immunology

authors： Rujeni N,Nausch N,Midzi N,Gwisai R,Mduluza T,Taylor DW,Mutapi F

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The classical clinical manifestation of untreated immunoglobulin deficiency comprises predominantly recurrent and complicated respiratory tract infections. Before the 1980s, little was known about the clinical manifestation of immunodeficiency in the general medical population, and also the availability of s...

journal_title：International archives of allergy and immunology

authors： Litzman J,Stikarovska D,Pikulova Z,Pavlik T,Pesak S,Thon V,Kuklinek P,Lokaj J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:L-selectin (CD62L) and Mac-1 (CD11b/CD18) play a crucial role in the infiltration of eosinophils. However, changes in CD62L and CD11b expression on eosinophils after stimulation with cytokines were little studied. METHODS:Eosinophils in peripheral blood of healthy volunteers were purified and cultured with ...

journal_title：International archives of allergy and immunology

authors： Momose T,Okubo Y,Horie S,Takashi S,Tsukadaira A,Suzuki J,Isobe M,Sekiguchi M

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The cysteinyl leukotrienes (CysLTs) mediate their biological actions through two receptors: CysLT(1) receptor and CysLT(2) receptor. OBJECTIVE:This study was undertaken to examine the direct effects of CysLTs on eosinophils, such as chemotaxis and degranulation, focusing on CysLT(1). METHODS:Eosinophils we...

journal_title：International archives of allergy and immunology

authors： Ohshima N,Nagase H,Koshino T,Miyamasu M,Yamaguchi M,Hirai K,Yamamoto K,Fujisawa T,Nakagawa N,Kishikawa K,Morita Y

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:A new lateral flow test (LFT) for office use provides information about sensitisation to common allergens. Concordance between LFT and skin-prick test (SPT) has not been assessed in epidemiological studies. The aim of this study is to determine LFT-SPT concordance in this field. METHODS:Plasma samples (n = ...

journal_title：International archives of allergy and immunology

authors： Sanchez-Bahillo M,Garcia-Marcos L,Martinez-Torres AE,Perez-Fernandez V,Sanchez-Solis M

更新日期：2010-01-01 00:00:00

abstract：:In studies designed to optimize the production and detection of anti-ovalbumin (anti-Oa) IgE in Ham/ICR mice, a range of doses of both Oa and pertussis toxin as the IgE adjuvant was explored. As determined by 48-hour passive cutaneous anaphylaxis (PCA) tests, the highest titre of anti-Oa IgE was obtained in a three-in...

journal_title：International archives of allergy and immunology

authors： Lindsay DS,Parton R,Wardlaw AC

更新日期：1994-11-01 00:00:00

abstract：:In murines, interleukins (IL) 3, 4, 9, and 10, nerve growth factor, and stem cell factor induce or promote growth and differentiation of mast cells (MC). Increased stimulation and synergy was observed when combinations of cytokines were used. In man, no growth factor for human MCs had been identified until recently, w...

journal_title：International archives of allergy and immunology

authors： Sillaber C,Sperr WR,Agis H,Spanblöchl E,Lechner K,Valent P

更新日期：1994-11-01 00:00:00

abstract：:We examined the capacity of interleukin-4 (IL) production from lymphocytes and basophils, isolated from the peripheral blood of allergic patients sensitive to house dust mite, after stimulation with mite extract. IL-4 production was measured by a sensitive bioassay based on coculture with CT.h4S (a human IL-4-responsi...

journal_title：International archives of allergy and immunology

authors： Ochi H,Tanaka T,Katada Y,Naka T,Aitani M,Hashimoto S,Maeda K,Toyoshima K,Igarashi T,Suemura M,Kishimoto T

更新日期：1996-11-01 00:00:00

abstract：:Because of a unique combination of challenges facing human immunodeficiency virus vaccine developers, a number of traditional and novel vaccine designs are being evaluated essentially in parallel. Monomeric proteins, poxvirus vectors, peptides, and particle-based candidate vaccines have entered or will soon enter huma...

journal_title：International archives of allergy and immunology

authors： Johnston MI

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Lactation is associated with an inhibited hypothalamic-pituitary-adrenal axis response to physical and psychological stress in women and female rats. However, suckling also improved mood and calmness in nonatopic lactating women. Relaxation by humor reduced allergen-induced skin wheal responses, while variou...

journal_title：International archives of allergy and immunology

authors： Kimata H

更新日期：2003-12-01 00:00:00