Varying allergen composition and content affects the in vivo allergenic activity of commercial Dermatophagoides pteronyssinus extracts.

abstract：:The present study has extended histochemical and functional investigations into rat mast cell heterogeneity using isolated mast cells from four connective tissue locations; the peritoneum, mesentery, lung and skin. On histological examination, mast cells from these locations displayed a range of phenotypes following f...

journal_title：International archives of allergy and immunology

authors： Tainsh KR,Pearce FL

更新日期：1992-01-01 00:00:00

abstract：:We examined the capacity of interleukin-4 (IL) production from lymphocytes and basophils, isolated from the peripheral blood of allergic patients sensitive to house dust mite, after stimulation with mite extract. IL-4 production was measured by a sensitive bioassay based on coculture with CT.h4S (a human IL-4-responsi...

journal_title：International archives of allergy and immunology

authors： Ochi H,Tanaka T,Katada Y,Naka T,Aitani M,Hashimoto S,Maeda K,Toyoshima K,Igarashi T,Suemura M,Kishimoto T

更新日期：1996-11-01 00:00:00

abstract：:Volumetric air sampling was performed at Corpus Christi, Tex., September 1987 to August 1989. Grass aeropollen during all of 1988 accounted for 15.3% of total pollen captured during two major peaks, one in May and another during September and October. The remaining grass pollen, about one-quarter of the total, was fou...

journal_title：International archives of allergy and immunology

authors： Lewis WH,Dixit AB,Wedner HJ

更新日期：1992-01-01 00:00:00

abstract：:Peritoneal eosinophilia was induced in rats using Ascaris suum extract as an antigen, and characteristics of granule proteins of eosinophils collected from the peritoneal cavity were investigated. Peritoneal eosinophilia was induced by injection of the antigen solution into the peritoneal cavity of the immunized rats ...

journal_title：International archives of allergy and immunology

authors： Watanabe M,Nittoh T,Suzuki T,Kitoh A,Mue S,Ohuchi K

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Pollen are monitored in Europe by a network of about 400 pollen traps, all operated manually. To date, automated pollen monitoring has only been feasible in areas with limited variability in pollen species. There is a need for rapid reporting of airborne pollen as well as for alleviating the workload of manu...

journal_title：International archives of allergy and immunology

authors： Oteros J,Pusch G,Weichenmeier I,Heimann U,Möller R,Röseler S,Traidl-Hoffmann C,Schmidt-Weber C,Buters JT

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Natural rubber latex proteins have been implicated in severe allergy in individuals exposed to latex products, particularly health care workers. Until recently, only crude antigens were available to study the immune response in these patients. In recent years a number of relevant allergens have been purified...

journal_title：International archives of allergy and immunology

authors： Johnson BD,Kurup VP,Sussman GL,Arif SA,Kelly KJ,Beezhold DH,Fink JN

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Depression and smoking contribute to the prognosis of autoimmune rheumatoid arthritis (RA). Advanced glycation end products (AGEs) are also detected in RA patients. This study correlates RA in patients with various levels of depression and a history of smoking through the detection of antibodies against AGEs...

journal_title：International archives of allergy and immunology

authors： Alouffi S,Sherwani S,Al-Mogbel MS,Sherwani MKA,Ali Khan MW

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:High osmolal ionic radiocontrast media (RCM) cause vascular release of endothelin-1 (ET-1) and activate mast cells. Iomeprol, a nonionic RCM, has recently been reported not to activate cardiac mast cells. This coronary angiography study was performed to extend those findings using another nonionic RCM, iopro...

journal_title：International archives of allergy and immunology

authors： Simon MR,Reher RL,Long PM,Yellayi K

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Although allergy to local anesthetics (LA) is rare, patients often report unwanted reactions after their administration. A history of anaphylaxis or an atypical reaction related to LA is an indication for typing a safe anesthetic for future surgical or dental procedures. AIM:The aim of the study was to dete...

journal_title：International archives of allergy and immunology

authors： Specjalski K,Kita-Milczarska K,Jassem E

更新日期：2013-01-01 00:00:00

abstract：:We evaluated whether c-myc and ras P-21 oncogene expression could identify familial polyposis coli/Gardner's syndrome patients at risk for colon cancer. Monoclonal antibodies recognizing c-myc and ras P-21 proteins were used in immunohistochemistry to stain 26 paraffin-embedded tissue specimens collected over 12 years...

journal_title：International archives of allergy and immunology

authors： Yuwono M,Rossi TM,Fisher JE,Tjota A

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:In naive rodents, repeated exposure to aerosolized antigen induces suppression of the Th2 response to the antigen. We hypothesized that more prolonged exposure of established asthma model to antigen aerosols may downregulate asthmatic phenotype. METHODS:After establishing an ovalbumin (OVA)-induced asthma m...

journal_title：International archives of allergy and immunology

authors： Sakai K,Yokoyama A,Kohno N,Hamada H,Hiwada K

更新日期：2001-10-01 00:00:00

abstract：:Allergens from the pollen of Parthenium hysterophorus (American feverfew), responsible for high incidence of allergic rhinitis, were found by immunoprint analysis to be localized on the surface of the pollen grains. The allergens were released very rapidly when extracted in vitro. The allergenic activity of the rapid ...

journal_title：International archives of allergy and immunology

authors： Gupta N,Sriramarao P,Kori R,Rao PV

更新日期：1995-08-01 00:00:00

abstract：:A significant increase in the incidence of allergy and asthma has been observed during the past decades. The background of this phenomenon has not been well explained, but changes in lifestyle and habits are heavily discussed as contributing factors. Among these is a too clean environment, which may predispose individ...

journal_title：International archives of allergy and immunology

authors： Zaknun D,Schroecksnadel S,Kurz K,Fuchs D

更新日期：2012-01-01 00:00:00

abstract：:The peripheral blood mononuclear cells (PBMC) from humans allergic to grass pollens (GR+ subjects) show strong in vitro proliferative responses to purified allergens from Lolium perenne pollen Lol p 1, and to a lesser extent to Lol p 2 and Lol p 3. By contrast, PBMC from grass allergic patients undergoing immunotherap...

journal_title：International archives of allergy and immunology

authors： Baskar S,Hamilton RG,Norman PS,Ansari AA

更新日期：1997-02-01 00:00:00

abstract：:Bronchial epithelial cells play an important role in the pathogenesis of some inflammatory diseases of bronchial mucosa. Epithelial-cell-derived cytokines are important in the elucidation of the mechanism by which airway inflammation occurs, especially in respiratory virus infection, because these cells are the primar...

journal_title：International archives of allergy and immunology

authors： Adachi M,Matsukura S,Tokunaga H,Kokubu F

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Accumulating evidence indicates that eotaxin is the primary mediator of tissue eosinophilia. In the present study, we analyzed the mechanisms of eotaxin generation by Th1-/Th2-derived cytokines in vitro. METHODS:Human dermal fibroblasts, human umbilical vein endothelial cells and A549 human bronchial epithe...

journal_title：International archives of allergy and immunology

authors： Miyamasu M,Misaki Y,Yamaguchi M,Yamamoto K,Morita Y,Matsushima K,Nakajima T,Hirai K

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Farming has been widely reported to be associated with decreased risk of developing atopic disorders, but underlying immunomodulatory mechanisms are still not fully defined. We delineated T-cell functions after induction of mucosal tolerance in the context of intranasally delivered organic dust compounds, li...

journal_title：International archives of allergy and immunology

authors： Gerhold K,Avagyan A,Reichert E,Blumchen K,Wahn U,Hamelmann E

更新日期：2008-01-01 00:00:00

abstract：:Fourteen Brown-Norway rats were pretreated with physiological saline (n = 7) or 500 micrograms Sephadex (n = 7) intratracheally. 24 h later, a bronchial provocation test was performed under pentobarbital anaesthesia using increasing doses of acetylcholine aerosol and the degree of bronchospasm was measured using a mod...

journal_title：International archives of allergy and immunology

authors： Kubin R,Deschl U,Linssen M,Wilhelms OH

更新日期：1992-01-01 00:00:00

abstract：:We aimed to evaluate the therapeutic effect of nebulized beclomethasone dipropionate (nBDP) on both allergic asthma and rhinitis. In a randomized, double-blind, placebo-controlled study, 40 children (mean age 10.7 ± 2.1 years) with allergic asthma and rhinitis received either nBDP (daily dose of 800 µg, administered t...

journal_title：International archives of allergy and immunology

authors： Profita M,Riccobono L,Bonanno A,Chanez P,Gagliardo R,Montalbano AM,Albano GD,Liotta G,Gjomarkaj M,La Grutta S

更新日期：2013-01-01 00:00:00

abstract：:We isolated a major wheat flour allergen with a molecular weight of 15-kD. The 15-kD allergen was purified from an extract of wheat flour by ammonium sulfate precipitation followed by gel filtration. Using the immunoblot technique, IgE, specifically directed towards the single isolated allergen, was detectable in 50% ...

journal_title：International archives of allergy and immunology

authors： Fränken J,Stephan U,Meyer HE,König W

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Patients with chronic urticaria (CU) in the UK could be referred to health care professionals (HCPs) with diverse specialties using different guidelines. The aims of the present study were to determine which CU guidelines HCPs in the UK use, which tests they use for the diagnosis of CU, and how they manage C...

journal_title：International archives of allergy and immunology

authors： Wu CH,Ardern-Jones MR,Eren E,Venter C

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The classical clinical manifestation of untreated immunoglobulin deficiency comprises predominantly recurrent and complicated respiratory tract infections. Before the 1980s, little was known about the clinical manifestation of immunodeficiency in the general medical population, and also the availability of s...

journal_title：International archives of allergy and immunology

authors： Litzman J,Stikarovska D,Pikulova Z,Pavlik T,Pesak S,Thon V,Kuklinek P,Lokaj J

更新日期：2010-01-01 00:00:00

abstract：:Eosinophils participate in the inflammatory response seen in allergy and helminthic infestation. Their release of granule-bound cationic proteins may play a role in these diseases. Therefore, we investigated mechanisms involved in the release of eosinophil cationic protein (ECP). Serum-opsonized zymosan was phagocytos...

journal_title：International archives of allergy and immunology

authors： Egesten A,Blom M,Calafat J,Janssen H,Knol EF

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:The widespread house ant, Monomorium pharaonis (pharaoh ant, PA), was recently identified as a potential cause of respiratory allergies. However, there are no reports of the distribution of PA allergens in various environments. We developed specific ELISA inhibition assays and measured the distribution and a...

journal_title：International archives of allergy and immunology

authors： Kim CW,Song JS,Choi SY,Park JW,Hong CS

更新日期：2007-01-01 00:00:00

abstract：:Mercuric chloride (HgCl(2)) has been proposed to be a mitogen for human blood lymphocytes in vitro. In our previous study, we demonstrated that HgCl(2) preferentially stimulates the CD4+ T cell subset to blast transformation and DNA synthesis and that the reaction is dependent on CD14+ accessory cells. In order to cha...

journal_title：International archives of allergy and immunology

authors： Loftenius A,Ekstrand J,Möller E

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Pseudomonas aeruginosa phospholipase C (PLC) is a critical component in the pathogenesis of severe P. aeruginosa infections. However, P. aeruginosa can produce a hemolytic (PLC-H) as well as a nonhemolytic (PLC-N) variant, both having a MW of about 77 kD. In the past, studies did not distinguish between both...

journal_title：International archives of allergy and immunology

authors： König B,Vasil ML,König W

更新日期：1997-02-01 00:00:00

abstract：:Phosphoinositide 3-kinases (PI3Ks) are known to be involved in a variety of cellular responses such as cell survival, proliferation, differentiation and cell migration. Recently, PI3Ks have been associated with the pathogenesis of asthma because various immune cells regulate allergic responses. Among the three classes...

journal_title：International archives of allergy and immunology

authors： Takeda M,Ito W,Tanabe M,Ueki S,Kihara J,Kato H,Tanigai T,Kayaba H,Sasaki T,Chihara J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The European tick, Argas reflexus, is an urban pest parasitizing urban pigeons and may cause a wide range of allergic reactions. METHODS:Specific IgE to A. reflexus, SDS-PAGE and IgE immunoblotting, performed with tick extract, were carried out in the sera of 6 patients who reported allergic reactions after...

journal_title：International archives of allergy and immunology

authors： Rolla G,Nebiolo F,Marsico P,Guida G,Bigo P,Riva G,Zanotta S

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:In vivo, all blood vessels are lined by a single layer of flattened noncycling endothelial cells. We tested the hypothesis that the maintenance of such a quiescent endothelial monolayer depends on homotypic contacts between not yet defined growth-inhibitory molecules located at interendothelial junctions. M...

journal_title：International archives of allergy and immunology

authors： Halama T,Staffler G,Hoch S,Stockinger H,Wolff K,Petzelbauer P

更新日期：1999-11-01 00:00:00

abstract：:IgE responsiveness to Dermatophagoides farinae body extract was compared by immunoblotting among four groups of mite-sensitive asthmatic children: group I aged 0-3, group II aged 4-7, group III aged 8-11 and group IV aged 12-15. In the group I subjects, the 15-kD component was bound by 88% of sera and strongly by 56% ...

journal_title：International archives of allergy and immunology

authors： Shibasaki M,Isoyama S,Takita H

更新日期：1994-01-01 00:00:00