Potential role of antioxidant food supplements, preservatives and colorants in the pathogenesis of allergy and asthma.

abstract：:Fibroblast-derived growth factors like SCF are able to upregulate the expression of mast cell characteristics in human multilineage hematopoietic progenitor cells. Other factors, like GM-CSF, have been reported to inhibit this process, probably by the competitive recruitment of cells not belonging to the mast cell lin...

journal_title：International archives of allergy and immunology

authors： Welker P,Grabbe J,Zuberbier T,Henz BM

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Measurement of fractional exhaled nitric oxide (FENO) is useful in assessing eosinophilic airway inflammation. Smoking may modify airway inflammation and reduce FENO levels, compromising the diagnostic value of FENO in smokers. How smoking influences FENO in atopic versus nonatopic asthmatics is unknown. The...

journal_title：International archives of allergy and immunology

authors： Rouhos A,Ekroos H,Karjalainen J,Sarna S,Haahtela T,Sovijärvi AR

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:DNA immunization and protein immunization with CpG motifs as adjuvants represent promising approaches in allergen-specific immunotherapy. OBJECTIVE:We investigated the effect of coinjection or prepriming with CpG-ODN on Th2-type responses induced by gene gun and protein immunization. METHODS:BALB/c mice we...

journal_title：International archives of allergy and immunology

authors： Hochreiter R,Hartl A,Freund J,Valenta R,Ferreira F,Thalhamer J

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Antiphospholipid antibodies (aPL) show great heterogeneity. Different phospholipids, with or without protein cofactor(s), and phospholipid binding proteins alone have been proposed as the target molecules for aPL. In order to determine the influence of phospholipid degradation products on the binding of aPL,...

journal_title：International archives of allergy and immunology

authors： Bozic B,Kveder T,Stegnar M,Morosini-Berus E,Kos-Golja M,Peternel P,Rozman B

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Mast cell tryptase has recently been reported to be involved in atherosclerotic plaque destabilization. However, the results of these reports are conflicting. METHODS:The aim of this study was to characterize the role of tryptase as a prognostic marker of patient cardiovascular complexity in acute coronary ...

journal_title：International archives of allergy and immunology

authors： Pastorello EA,Morici N,Farioli L,Di Biase M,Losappio LM,Nichelatti M,Lupica L,Schroeder JW,Stafylaraki C,Klugmann S

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Five to twenty percent of healthy, nonasthmatic individuals exhibit airway hyperreactivity. Because cytokines are important intermediates in airway responses, we investigated the relationship between serum cytokines and airway responsiveness in a well-characterized population of pregnant women. METHODS:We a...

journal_title：International archives of allergy and immunology

authors： Tsunoda M,Litonjua AA,Kuniak MP,Weiss ST,Satoh T,Guevarra L,Tollerud DJ

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:A number of different molecules are known to be involved in the signal pathway to release histamine from mast cells, among which arachidonic acid (AA) is one of the key mediators. On the other hand, we found that the application of compound 48/80, a typical histamine liberator, generated superoxide in mast c...

journal_title：International archives of allergy and immunology

authors： Sakaguchi M,Fukuishi N,Teramoto K,Miyazaki M,Huh NH,Namba M,Akagi M

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Exposure to the house dust mite Blomia tropicalis is increasingly being implicated as a major risk factor for asthma exacerbations in sensitized individuals. The objective of this study is to clone and characterize B. Tropicalis allergens in order to better define their role in allergic asthma. METHODS:A la...

journal_title：International archives of allergy and immunology

authors： Flores I,Mora C,Rivera E,Donnelly R,Montealegre F

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:IgE mediates immediate-type hypersensitivity reactions responsible for various allergic symptoms. It is secreted by IgE-producing plasma cells, which differentiate from B cells expressing membrane-bound IgE (mIgE) on their surface. The epsilon-chain of human mIgE contains a membrane-anchoring peptide and an ...

journal_title：International archives of allergy and immunology

authors： Chen HY,Liu FT,Hou CM,Huang JS,Sharma BB,Chang TW

更新日期：2002-08-01 00:00:00

abstract：:Human colostrum and a high molecular weight colostrum fraction (HMWF; > 14,000 D) prevented the adhesion of localized adherent (LA+) O111:H-enteropathogenic Escherichia coli (EPEC) to HeLa cells. This effect was abolished after absorption with an O111:H-LA + EPEC strain, but absorption with a LA- strain of same seroty...

journal_title：International archives of allergy and immunology

authors： Camara LM,Carbonare SB,Silva ML,Carneiro-Sampaio MM

更新日期：1994-01-01 00:00:00

abstract：:Microwave radiation from mobile phones enhanced skin wheal responses induced by house dust mite and Japanese cedar pollen while it had no effect on wheal responses induced by histamine in patients with atopic eczema/dermatitis syndrome (AEDS). Microwave radiation also increased plasma levels of substance P (SP) and va...

journal_title：International archives of allergy and immunology

authors： Kimata H

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Subcutaneous immunotherapy for respiratory allergy has shown a long lasting efficacy after its discontinuation, whereas evidence in the case of sublingual immunotherapy (SLIT) is weak. This retrospective study evaluates whether SLIT exerts a long-lasting effect and whether it relates to its duration. METHOD...

journal_title：International archives of allergy and immunology

authors： Marogna M,Bruno M,Massolo A,Falagiani P

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Specific immunotherapy for respiratory allergy, a seasonal disease, significantly reduces the inflammatory process, attenuating the clinical symptoms. The mechanism for the clinical beneficial effect of immunotherapy has not yet been clarified. Melatonin shows a circadian and seasonal variation and together ...

journal_title：International archives of allergy and immunology

authors： Girón-Caro F,Muñoz-Hoyos A,Ruiz-Cosano C,Bonillo-Perales A,Molina-Carballo A,Escames G,Macías M,Acuña-Castroviejo D

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:High osmolal ionic radiocontrast media (RCM) cause vascular release of endothelin-1 (ET-1) and activate mast cells. Iomeprol, a nonionic RCM, has recently been reported not to activate cardiac mast cells. This coronary angiography study was performed to extend those findings using another nonionic RCM, iopro...

journal_title：International archives of allergy and immunology

authors： Simon MR,Reher RL,Long PM,Yellayi K

更新日期：2003-05-01 00:00:00

abstract：:Cross-linking of FcepsilonRI on mast cells elicits positive signal transduction cascades that lead to the release of a variety of proinflammatory mediators. Mouse mast cells also express gp49B1 on their surface, an immunoglobulin superfamily member that bears two immunoreceptor tyrosine-based inhibitory motifs in its ...

journal_title：International archives of allergy and immunology

authors： Katz HR

更新日期：1999-02-01 00:00:00

abstract：:Because of a unique combination of challenges facing human immunodeficiency virus vaccine developers, a number of traditional and novel vaccine designs are being evaluated essentially in parallel. Monomeric proteins, poxvirus vectors, peptides, and particle-based candidate vaccines have entered or will soon enter huma...

journal_title：International archives of allergy and immunology

authors： Johnston MI

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Little information is available on eosinophil activation and the cytokine profile in virus-induced acute exacerbation of bronchial asthma; therefore, we examined the effects of treatments that included systemic corticosteroids on serum eosinophil cationic protein (ECP) and 17 cytokines/chemokines in rhinovir...

journal_title：International archives of allergy and immunology

authors： Kato M,Yamada Y,Maruyama K,Hayashi Y

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Severe asthma is a heterogeneous disease, which is characterized by airway damage and remodeling. All triggers of asthma, such as allergens, bacteria, viruses, and pollutants, interact with the airway epithelial cells, which drive the airway inflammatory response through the release of cytokines, particularl...

journal_title：International archives of allergy and immunology

authors： Boita M,Heffler E,Omedè P,Bellocchia M,Bussolino C,Solidoro P,Giorgis V,Guerrera F,Riva G,Brussino L,Bucca C,Rolla G

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Hereditary angioedema (HAE) with C1 inhibitor (C1-INH) deficiency is a rare autosomal dominant disease. Although the first symptoms can appear in childhood, the diagnosis's delay has a strong impact on the patient's quality of life. We analyzed clinical and laboratory characteristics and the drug therapy o...

journal_title：International archives of allergy and immunology

authors： Araújo-Simões J,Boanova AGP,Constantino-Silva RN,Fragnan NTML,Pinto JA,Minafra FG,Gonçalves RF,Valle SRD,Alonso MLO,Dortas SD,Goudouris ES,Rêgo-Silva AM,Marques MM,Serpa FS,Chong-Neto HJ,Nelson RF,Mansour E,Moreira IF,

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:Assessing high-sensitivity C-reactive protein (hs-CRP) in relation to allergic endpoints can shed light on both the mechanisms of allergic disease development and early non-communicable disease prevention. However, only a few epidemiological studies so far have investigated the relationship in children and a...

journal_title：International archives of allergy and immunology

authors： Yang BY,Markevych I,Harris C,Standl M,Schikowski T,Koletzko S,Herberth G,Bauer CP,von Berg A,Berdel D,Dong GH,Heinrich J

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Cow's milk protein allergy (CMA) is the most common type of food allergy in childhood and exclusion diet is a challenge for patients. OBJECTIVE:The study aim was to investigate the frequency of tolerance to baked foods containing milk and evaluate immediate skin prick test (SPT) and specific IgEs for diff...

journal_title：International archives of allergy and immunology

authors： Vilar LK,Araújo FA,Santos TP,Menezes TT,Cheik MF,Segundo GRS

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND AND AIM:Although still controversial, drug provocation tests (DPTs) are considered by many as the gold standard for diagnosis of drug hypersensitivity. No studies have addressed the opinion of patients submitted to DPT. We aimed to determine patient satisfaction with diagnostic DPT and their perception of it...

journal_title：International archives of allergy and immunology

authors： Gomes ER,Kvedariene V,Demoly P,Bousquet PJ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:It has been shown that antigen presentation by resting B cells can induce tolerance to intravenously administered protein antigens, but the role of resting B cells in the induction of oral tolerance is unclear. METHODS:Mice continuously treated since birth with rabbit anti-mouse IgM serum for 5 weeks were d...

journal_title：International archives of allergy and immunology

authors： Peng HJ,Chang ZN,Kuo SW,Lee CC,Tzau YY

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:The role of food allergens in the induction of allergic reactions in the airways is not completely understood. The aim of the present study was to evaluate fluorocytometric assays of the peripheral blood during food challenge tests in children with asthma and food allergy. PATIENTS AND METHODS:22 children w...

journal_title：International archives of allergy and immunology

authors： Krogulska A,Wasowska-Królikowska K,Polakowska E,Chrul S

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Omalizumab, an anti-immunoglobulin E (IgE) monoclonal antibody, inhibits the binding of circulating IgE to mast cells and basophils, resulting in fewer episodes of airway inflammation, asthma symptoms and exacerbations in patients with severe allergic asthma. Treatment of patients with asthma using omalizuma...

journal_title：International archives of allergy and immunology

authors： Mizuma H,Tanaka A,Uchida Y,Fujiwara A,Manabe R,Furukawa H,Kuwahara N,Fukuda Y,Kimura T,Jinno M,Ohta S,Yamamoto M,Matsukura S,Adachi M,Sagara H

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:15-Deoxy-Delta(12,14)-prostaglandin J2 (15d-PGJ2), a major prostanoid metabolized from prostaglandin D2 (PGD2), plays an important role in various biological processes including inflammatory responses. 15d-PGJ2 exerts its effects through two major receptors, chemoattractant receptor- homologous molecule expr...

journal_title：International archives of allergy and immunology

authors： Chiba T,Ueki S,Ito W,Kato H,Takeda M,Kayaba H,Furue M,Chihara J

更新日期：2009-01-01 00:00:00

abstract：:Peritoneal mast cells of Syrian hamsters release histamine to the action of concanavalin A (Con A) in dose-dependent fashion. The rate of release was very rapid in the first seconds of cell activation and completed in 60 s after the challenge. Morphological changes concomitant to the lectin treatment, followed by elec...

journal_title：International archives of allergy and immunology

authors： Wyczolkowska J,Rydzynski K,Prouvost-Danon A

更新日期：1992-01-01 00:00:00

abstract：:Bronchial epithelial cells play an important role in the pathogenesis of some inflammatory diseases of bronchial mucosa. Epithelial-cell-derived cytokines are important in the elucidation of the mechanism by which airway inflammation occurs, especially in respiratory virus infection, because these cells are the primar...

journal_title：International archives of allergy and immunology

authors： Adachi M,Matsukura S,Tokunaga H,Kokubu F

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Both oral and intravenous inhibitors of cyclic nucleotide phosphodiesterase (PDE) 3 and PDE4 have been shown to have bronchodilator and/or pulmonary antiallergic effects but their adverse effects limit the clinical use. The purpose of the present study was to assess the bronchoprotective effect of intrabronc...

journal_title：International archives of allergy and immunology

authors： Fujimura M,Tachibana H,Myou S,Kita T,Matsuda T

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Farming has been widely reported to be associated with decreased risk of developing atopic disorders, but underlying immunomodulatory mechanisms are still not fully defined. We delineated T-cell functions after induction of mucosal tolerance in the context of intranasally delivered organic dust compounds, li...

journal_title：International archives of allergy and immunology

authors： Gerhold K,Avagyan A,Reichert E,Blumchen K,Wahn U,Hamelmann E

更新日期：2008-01-01 00:00:00