GM-CSF downregulates expression of tryptase, Fc epsilon RI and histamine in HMC-1 mast cells.

abstract：BACKGROUND:The purpose of this study was to investigate lymphocyte adhesion to Kupffer cells as a component of an immune-mediated mechanism for halothane hepatitis. METHODS:Kupffer cells were isolated from guinea pigs exposed to 1.0% halothane/40% oxygen and cultured with various synthetic antigens (trifluoroacetyl-pr...

journal_title：International archives of allergy and immunology

authors： Furst SM,Gandolfi AJ

更新日期：1997-09-01 00:00:00

abstract：:To determine whether the costimulatory signal via CD28/B7 interaction is required for causing allergic inflammation, we examined the effect of administration of CTLA4-Ig, a fusion protein of the extracellular domain of CTLA4 and human IgG1-constant region, at the time of sensitization, on antigen-induced eosinophil in...

journal_title：International archives of allergy and immunology

authors： Kasai M,Kumano K,Kurasawa K,Nakao A,Saito Y,Iwamoto I

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:High antibiotic prescribing rates for adults with an asthma exacerbation have been reported in developed countries, but few studies have assessed the variation of antibiotic and adjunctive treatment in the routine care of children. OBJECTIVE:We evaluated the trends in health resource utilization for childre...

journal_title：International archives of allergy and immunology

authors： Okubo Y,Horimukai K,Michihata N,Morita K,Matsui H,Fushimi K,Yasunaga H

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Hymenoptera venom allergy (HVA) has a prevalence of 3% in adults. Although patients have no ongoing symptoms, they often suffer from an impairment of their psychological well-being and quality of life. OBJECTIVE:The aim of this study was to analyze sex-specific differences regarding the psychological burden...

journal_title：International archives of allergy and immunology

authors： Schoeben LS,Bubak C,Schaarschmidt ML,Schmieder A

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori, the main cause of gastritis and peptic ulcer, has been associated with idiopathic chronic urticaria (ICU), an immunological skin disorder of unknown origin. Eosinophilic cationic protein (ECP) is a cytotoxic molecule secreted by the activated eosinophils involved in the pathogenesis of I...

journal_title：International archives of allergy and immunology

authors： Ojetti V,Armuzzi A,De Luca A,Nucera E,Franceschi F,Candelli M,Zannoni GF,Danese S,Di Caro S,Vastola M,Schiavino D,Gasbarrini G,Patriarca G,Pola P,Gasbarrini A

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:The role of food allergens in the induction of allergic reactions in the airways is not completely understood. The aim of the present study was to evaluate fluorocytometric assays of the peripheral blood during food challenge tests in children with asthma and food allergy. PATIENTS AND METHODS:22 children w...

journal_title：International archives of allergy and immunology

authors： Krogulska A,Wasowska-Królikowska K,Polakowska E,Chrul S

更新日期：2009-01-01 00:00:00

abstract：:IgE responsiveness to Dermatophagoides farinae body extract was compared by immunoblotting among four groups of mite-sensitive asthmatic children: group I aged 0-3, group II aged 4-7, group III aged 8-11 and group IV aged 12-15. In the group I subjects, the 15-kD component was bound by 88% of sera and strongly by 56% ...

journal_title：International archives of allergy and immunology

authors： Shibasaki M,Isoyama S,Takita H

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:The importance of fungal allergens in the development of allergic diseases in a desert environment is uncertain. This study evaluated the prevalence of IgE sensitization to moulds among patients with allergic respiratory diseases in Kuwait - a desert country. METHODS:A total of 810 patients (male:female rat...

journal_title：International archives of allergy and immunology

authors： Ezeamuzie CI,Al-Ali S,Khan M,Hijazi Z,Dowaisan A,Thomson MS,Georgi J

更新日期：2000-04-01 00:00:00

abstract：:At an international hereditary angioedema (HAE) expert meeting, results from a survey were used to guide discussion on how best to advise patients on self-administering intravenous C1 esterase inhibitor therapy. Treatment differences across Europe were highlighted, together with the practicalities of self-administrati...

journal_title：International archives of allergy and immunology

authors： Symons C,Rossi O,Magerl M,Andritschke K

更新日期：2013-01-01 00:00:00

abstract：:A 73-year-old man developed organized pneumonia with severe right-sided eosinophilic pleural effusion (PE). CD69+ and HLA-DR+ eosinophils in PE were 90 and 31%, respectively, but were undetectable in peripheral blood (PB). CD4+, CD45RA+ (naive) and CD4+, CD45RO+ (memory) cells in PB, PE and bronchoalveolar lavage (BAL...

journal_title：International archives of allergy and immunology

authors： Hossain M,Okubo Y,Yamaguchi S,Horie S,Itoh S,Sugii S,Takatsu K,Oguchi T,Sekiguchi M

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Numerous strategies have been proposed for the treatment of peanut allergies, but despite the steady advancement in our understanding of atopic immune responses and the increasing number of deaths each year from peanut anaphylaxis, there is still no safe, effective, specific therapy for the peanut-sensitive ...

journal_title：International archives of allergy and immunology

authors： Bannon GA,Cockrell G,Connaughton C,West CM,Helm R,Stanley JS,King N,Rabjohn P,Sampson HA,Burks AW

更新日期：2001-01-01 00:00:00

abstract：:We studied the binding activities of IgE, IgG and IgA antibodies in patients with allergy to hen's egg white against two different ovalbumin (OVA) preparations, which were physically or chemically denatured OVA and enzyme-digested OVA fragments. The binding activities of IgE antibodies to these OVA preparations with t...

journal_title：International archives of allergy and immunology

authors： Honma K,Kohno Y,Saito K,Shimojo N,Tsunoo H,Niimi H

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Common variable immunodeficiency (CVID) is the most common primary antibody deficiency syndrome in humans, but it remains a diagnosis of exclusion in most cases. Several genetically defined primary immunodeficiencies mimic CVID. Among them is the X-linked lymphoproliferative syndrome (XLP) which was shown to...

journal_title：International archives of allergy and immunology

authors： Salzer U,Hagena T,Webster DB,Grimbacher B

更新日期：2008-01-01 00:00:00

abstract：:Factors are discussed as potential diagnostic parameters of atopic disorders. The amounts of sCD23 in sera from newborn children (n = 4,329) were determined by radioimmunoassay with monoclonal antibodies specific for CD23. The sCD23 levels ranged between 0 and 81.5 ng/ml of CD23-specific mAb. Furthermore, the sera of ...

journal_title：International archives of allergy and immunology

authors： Bujanowski-Weber J,Knöller I,Wahn U,König W

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:A negative association has been observed between infections and allergy in several studies. The aim of the present study was to examine whether tuberculosis and leprosy patients have more or fewer allergies than healthy individuals. METHOD:Sera from tuberculosis patients, leprosy patients and healthy contro...

journal_title：International archives of allergy and immunology

authors： Ellertsen LK,Wiker HG,Egeberg NT,Hetland G

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:omega-5 gliadin is a major allergen in exercise-induced wheat allergy (EIWA), but it is also implicated in immediate-type reactions to wheat. An ImmunoCAP assay to measure omega-5 gliadin-specific IgE has become available. This study aimed to evaluate this new biological test in wheat allergy diagnosis and t...

journal_title：International archives of allergy and immunology

authors： Jacquenet S,Morisset M,Battais F,Denery-Papini S,Croizier A,Baudouin E,Bihain B,Moneret-Vautrin DA

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Asthma, allergic conditions, and COPD overlap, but the effect of them and their combinations on disease severity, need for drugs, use of healthcare, and costs is poorly known. OBJECTIVE:To study how different allergic diseases co-occur in asthma and allergy patients and evaluate the use of medication well a...

journal_title：International archives of allergy and immunology

authors： Jantunen J,Haahtela T,Salimäki J,Linna M,Mäkelä M,Pelkonen A,Kauppi P

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The hemagglutinin (HA) of influenza viruses is one of the major targets of the humoral response. The role of serum antibody to HA in the protection against infection has been demonstrated by long-standing observation. In previous studies, we suggested that an epitope vaccine might be a new strategy against t...

journal_title：International archives of allergy and immunology

authors： Lu Y,Ding J,Liu W,Chen YH

更新日期：2002-03-01 00:00:00

abstract：:In studies designed to optimize the production and detection of anti-ovalbumin (anti-Oa) IgE in Ham/ICR mice, a range of doses of both Oa and pertussis toxin as the IgE adjuvant was explored. As determined by 48-hour passive cutaneous anaphylaxis (PCA) tests, the highest titre of anti-Oa IgE was obtained in a three-in...

journal_title：International archives of allergy and immunology

authors： Lindsay DS,Parton R,Wardlaw AC

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:The coexistence of asthma and allergic rhinitis (AR) and its distinct association with obesity have been reported. However, few studies have differentiated the two types of AR, i.e., perennial (PAR) and seasonal AR (SAR), with regard to their associations with asthma and obesity. The aim of this study was to...

journal_title：International archives of allergy and immunology

authors： Matsumoto M,Konno S,Kimura H,Takei N,Kimura H,Shimizu K,Goudarzi H,Suzuki M,Hashino S,Nishimura M

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Pathologic accumulation and activation of mast cells and eosinophils are implicated in allergic and inflammatory diseases. Sialic acid-binding immunoglobulin-like lectin (Siglec)-8 is an inhibitory receptor selectively expressed on mast cells, eosinophils and, at a lower extent, basophils. When engaged wit...

journal_title：International archives of allergy and immunology

authors： Youngblood BA,Brock EC,Leung J,Falahati R,Bryce PJ,Bright J,Williams J,Shultz LD,Greiner DL,Brehm MA,Bebbington C,Tomasevic N

更新日期：2019-01-01 00:00:00

abstract：:Recent studies have demonstrated that pulmonary surfactant protein (SP)-A plays a potential role in modifying inflammation and immune function. To see whether SP-A could modify IL-8 production and release by eosinophils stimulated with ionomycin, SP-A purified from surfactant recovered from patients with alveolar prot...

journal_title：International archives of allergy and immunology

authors： Cheng G,Ueda T,Nakajima H,Nakajima A,Kinjyo S,Motojima S,Fukuda T

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Previous studies have shown a negative association between ACP1 *B/*C genotype and total IgE level. ACP1 (acid phosphatase locus 1) is a polymorphic phosphotyrosine phosphatase that interacts with IL4-RA and is involved in T cell receptor signaling. METHODS:In the present paper, we have studied the relation...

journal_title：International archives of allergy and immunology

authors： Greco E,Bottini N,Canu G,Maccari AM,Saccucci P,Gloria-Bottini F,Fontana L

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD) and food allergy (FA) are common childhood diseases, which may either be interrelated or be the result of skin barrier disruption and gut mucosal dysbiosis. Although some evidence suggests the efficacy of emollients and synbiotics, there is no conclusive evidence on the use of these in...

journal_title：International archives of allergy and immunology

authors： Dissanayake E,Tani Y,Nagai K,Sahara M,Mitsuishi C,Togawa Y,Suzuki Y,Nakano T,Yamaide F,Ohno H,Shimojo N

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Immunoglobulin G4-related disease (IgG4-RD) is a systemic immunological disorder characterized by fibro-inflammatory conditions; however, the pathobiology of IgG4-RD has not been fully identified. OBJECTIVE:This study aimed to analyze systemic differences of innate and adaptive immune cells from healthy con...

journal_title：International archives of allergy and immunology

authors： Sohn KH,Ham J,Chung SJ,Kang HR,Kim HY

更新日期：2020-01-01 00:00:00

abstract：:Human mononuclear leukocytes (MNL), probably OKT4-positive T cells, produced an eosinophil chemotactic factor (ECF) when they were cocultured with irradiated BALL-1, a B cell lymphoma line. Treatment of MNL, with anti-IL-2 antibody failed to suppress BALL-1-induced ECF production. Periodate-lysine-paraformaldehyde-fix...

journal_title：International archives of allergy and immunology

authors： Yoshida N,Ueno M,Saita N,Hirashima M

更新日期：1994-01-01 00:00:00

abstract：:The participation of platelets in the protection against larval Taenia taeniaeformis was studied. CB-17 SCID mice, susceptible to T. taeniaeformis, were protected against a challenge infection with T. taeniaeformis by the passive transfer of platelets from T. taeniaeformis-infected normal CB-17 mice, resistant to T. t...

journal_title：International archives of allergy and immunology

authors： Kakuda T,Ooi HK,Oku Y,Kamiya M

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Patients with allergic rhinoconjunctivitis are susceptible to both nasal and ocular symptoms. The conjunctival provocation test (CPT) is an established diagnostic procedure used in allergic rhinoconjunctivitis, particularly to document a patient's current reactivity to allergens. To date, there are no intern...

journal_title：International archives of allergy and immunology

authors： Dogan S,Astvatsatourov A,Deserno TM,Bock F,Shah-Hosseini K,Michels A,Mösges R

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:Venom immunotherapy (VIT) is considered to be the gold-standard treatment for patients with Hymenoptera venom allergy. Data regarding VIT in bee venom (BV) allergic patients are scarce. AIM:The aim of this study was to evaluate the outcome of VIT in patients with exclusive BV allergy and to try to define ...

journal_title：International archives of allergy and immunology

authors： Rosman Y,Nashef F,Cohen-Engler A,Meir-Shafrir K,Lachover-Roth I,Confino-Cohen R

更新日期：2019-01-01 00:00:00

abstract：:Partially purified commercial phospholipase D (PLD) was fractionated by dye-ligand affinity chromatography and nondenaturing polyacrylamide gel electrophoresis (PAGE). Active material migrated as three bands on SDS-PAGE. The two higher-abundance species were shown to have identical N-terminal sequences, while the thir...

journal_title：International archives of allergy and immunology

authors： Dinh TT,McClure GD,Kennerly DA

更新日期：1995-05-01 00:00:00