Objectifying the conjunctival provocation test: photography-based rating and digital analysis.

abstract：:Thioredoxin (TRX) is a redox-active protein that regulates reactive oxidative metabolism and plays a crucial role in the antioxidant system in regulating the reduction/oxidation balance by scavenging reactive oxygen species, which is implicated in the mechanism of asthma. As for the mechanisms by which TRX exerts its ...

journal_title：International archives of allergy and immunology

authors： Ito W,Kobayashi N,Takeda M,Ueki S,Kayaba H,Nakamura H,Yodoi J,Chihara J

更新日期：2011-01-01 00:00:00

abstract：:The case of a 46-year-old man with a chronic cough with sputum eosinophilia (atopic cough) caused by Trichosporon cutaneum serotype II (Trichosporon asahii) is reported. The diagnosis was made with the inhalation challenge test with T. asahii antigen. He was admitted for the diagnosis and treatment of a severe nonprod...

journal_title：International archives of allergy and immunology

authors： Ogawa H,Fujimura M,Amaike S,Nishiura Y,Nakagawa-Yoshida K,Suga M,Ando M,Matsuda T

更新日期：1998-06-01 00:00:00

abstract：:CD95 (APO-1) is a member of the TNF/nerve growth factor receptor superfamily, which is expressed on the surface of different types of cells. Cross-linking of CD95 leads to the induction of apoptosis. This may be of importance in many physiological systems, but seems to play a special role for the maintenance of immuno...

journal_title：International archives of allergy and immunology

authors： Lechner H,Amort M,Steger MM,Maczek C,Grubeck-Loebenstein B

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Antiphospholipid antibodies (aPL) show great heterogeneity. Different phospholipids, with or without protein cofactor(s), and phospholipid binding proteins alone have been proposed as the target molecules for aPL. In order to determine the influence of phospholipid degradation products on the binding of aPL,...

journal_title：International archives of allergy and immunology

authors： Bozic B,Kveder T,Stegnar M,Morosini-Berus E,Kos-Golja M,Peternel P,Rozman B

更新日期：1997-01-01 00:00:00

abstract：:Elevated levels of ovine reaginic antibody were induced by immunization with Ascaris suum antigens. The PCA activity of this antibody persisted in the skin of sheep for 20 days and was abolished by heating to 56 degrees C, suggesting that it was immunoglobulin E. Attempts to isolate IgE from this hyperimmune serum by ...

journal_title：International archives of allergy and immunology

authors： Yilmaz H,Roe JM,Morgan KL

更新日期：1993-01-01 00:00:00

abstract：:Oxatomide (OXA), a histamine H1 receptor antagonist, is effective in the treatment of patients with allergic rhinitis, some allergic skin disorders, and bronchial asthma. We have characterized the effect of OXA on the immunologic release of preformed (histamine and tryptase) and de novo synthesized mediators (leukotri...

journal_title：International archives of allergy and immunology

authors： Patella V,de Crescenzo G,Marino O,Spadaro G,Genovese A,Marone G

更新日期：1996-09-01 00:00:00

abstract：:In the present study, we investigated the role of resident peritoneal cells as well as the mediators involved in the eosinophil migration induced by large volumes of physiological saline. Two consecutive intraperitoneal injections of saline given 48 h apart, induced a selective recruitment of eosinophils into the cavi...

journal_title：International archives of allergy and immunology

authors： Oliveira SH,Faccioli LH,Cunha FQ,Ferreira SH

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Exposure to the house dust mite Blomia tropicalis is increasingly being implicated as a major risk factor for asthma exacerbations in sensitized individuals. The objective of this study is to clone and characterize B. Tropicalis allergens in order to better define their role in allergic asthma. METHODS:A la...

journal_title：International archives of allergy and immunology

authors： Flores I,Mora C,Rivera E,Donnelly R,Montealegre F

更新日期：2003-01-01 00:00:00

abstract：:Mast cell hyperplasia is found in different pathologies such as chronic inflammatory processes, fibrotic disorders, wound healing or neoplastic tissue transformation. The functional significance of the accumulation of mast cells in these processes is largely unknown. It is now established that bone marrow-derived mast...

journal_title：International archives of allergy and immunology

authors： Bischoff SC,Sellge G

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Fusion proteins assembling multiple allergens can be engineered by recombinant DNA technologies in order to produce tools for diagnostic and immunotherapeutic purposes. Herein, we developed and characterized chimeras assembling Der p 1 and Der p 2 allergens as potential candidate vaccines against house dust ...

journal_title：International archives of allergy and immunology

authors： Bussières L,Bordas-Le Floch V,Bulder I,Chabre H,Nony E,Lautrette A,Berrouet C,Nguefeu Y,Horiot S,Baron-Bodo V,Van Overtvelt L,De Conti AM,Schlegel A,Maguet N,Mouz N,Lemoine P,Batard T,Moingeon P

更新日期：2010-01-01 00:00:00

abstract：:In studies designed to optimize the production and detection of anti-ovalbumin (anti-Oa) IgE in Ham/ICR mice, a range of doses of both Oa and pertussis toxin as the IgE adjuvant was explored. As determined by 48-hour passive cutaneous anaphylaxis (PCA) tests, the highest titre of anti-Oa IgE was obtained in a three-in...

journal_title：International archives of allergy and immunology

authors： Lindsay DS,Parton R,Wardlaw AC

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Exposure to Aspergillus fumigatus allergens results in the sensitization and the development of allergic bronchopulmonary aspergillosis in susceptible individuals. Aspergillus antigen consists of a number of chemically diverse components and their cumulative or synergistic effect may result in disease. When ...

journal_title：International archives of allergy and immunology

authors： Kurup VP,Xia JQ,Shen HD,Rickaby DA,Henderson JD Jr,Fink JN,Chou H,Kelly KJ,Dawson CA

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase (MMP)-2, MMP-9 and MMP-13 can degrade type IV collagen which is the major component of the basement membrane zone (BMZ). In bullous pemphigoid (BP), the separation occurs within the BMZ. OBJECTIVE:To evaluate the involvement of MMPs in the pathogenesis of BP, we examined the express...

journal_title：International archives of allergy and immunology

authors： Niimi Y,Pawankar R,Kawana S

更新日期：2006-01-01 00:00:00

abstract：:The present study has extended histochemical and functional investigations into rat mast cell heterogeneity using isolated mast cells from four connective tissue locations; the peritoneum, mesentery, lung and skin. On histological examination, mast cells from these locations displayed a range of phenotypes following f...

journal_title：International archives of allergy and immunology

authors： Tainsh KR,Pearce FL

更新日期：1992-01-01 00:00:00

abstract：:Fourteen Brown-Norway rats were pretreated with physiological saline (n = 7) or 500 micrograms Sephadex (n = 7) intratracheally. 24 h later, a bronchial provocation test was performed under pentobarbital anaesthesia using increasing doses of acetylcholine aerosol and the degree of bronchospasm was measured using a mod...

journal_title：International archives of allergy and immunology

authors： Kubin R,Deschl U,Linssen M,Wilhelms OH

更新日期：1992-01-01 00:00:00

abstract：:HIV-1 RNA has become the standard for monitoring antiretroviral therapies. Dogma predicts, however, that a viral protein like p24 should be at least as good a marker of HIV disease activity, provided that it is measured with sufficient sensitivity and accuracy. Simple modifications including use of a more efficient vi...

journal_title：International archives of allergy and immunology

authors： Schüpbach J

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Diethylhexyl phthalate (DEHP) and diisononyl phthalate (DINP), two commonly used plasticizers in flexible polyvinylchloride formulations, have potentially adverse effects on human health. However, the influence of these diphthalates on allergic responses remains unclear. In this study we examined the effects...

journal_title：International archives of allergy and immunology

authors： Lee MH,Park J,Chung SW,Kang BY,Kim SH,Kim TS

更新日期：2004-07-01 00:00:00

abstract：:Tyrosine phosphorylation of STAT1alpha in eosinophils after IFN-gamma stimulation has been shown, but the biological significance of eosinophil STAT1alpha activation in transmitting the signals through the IFN-gamma receptor remains unknown. The purpose of this study is to determine whether STAT1 is involved in the re...

journal_title：International archives of allergy and immunology

authors： Ochiai K,Otaka K,Ito M,Tomioka H

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:The presence of autoantibodies reacting with the high affinity IgE receptor (FcepsilonRIalpha) usually indicates a more severe form of chronic urticaria (CU). Previously, we showed an increased lymphocyte reactivity in CU patients; however, the relation between enhanced cellular immunity and the presence of ...

journal_title：International archives of allergy and immunology

authors： Hidvégi B,Nagy E,Szabó T,Temesvári E,Marschalkó M,Kárpáti S,Horváth A,Gergely P

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:The high-affinity IgE receptor, FcepsilonRI, is unresponsive on mast cells and basophils from people in several populations through an unknown mechanism. Similarly, FcepsilonRI-positive basophils from 'nonreleasers' are IgE-unresponsive and are deficient in the tyrosine kinase Syk. OBJECTIVE:To test the hyp...

journal_title：International archives of allergy and immunology

authors： Kepley CL

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Mast cell tryptase has recently been reported to be involved in atherosclerotic plaque destabilization. However, the results of these reports are conflicting. METHODS:The aim of this study was to characterize the role of tryptase as a prognostic marker of patient cardiovascular complexity in acute coronary ...

journal_title：International archives of allergy and immunology

authors： Pastorello EA,Morici N,Farioli L,Di Biase M,Losappio LM,Nichelatti M,Lupica L,Schroeder JW,Stafylaraki C,Klugmann S

更新日期：2014-01-01 00:00:00

abstract：:Nonspecific hyperreactivity to a number of physical, chemical and pharmacological agents in a common characteristics of allergic subjects, which is strictly related to the inflammatory events consequent to an allergic reaction. Hyperosmolar stimulus has previously been shown to cause an inflammatory response inducing ...

journal_title：International archives of allergy and immunology

authors： Ciprandi G,Buscaglia S,Pesce G,Lotti R,Rolando M,Bagnasco M,Canonica GW

更新日期：1994-05-01 00:00:00

abstract：:Ever since the realization that T lymphocytes are key players in the defense against pathogens and tumors, a major aim of immunologists has been to understand the relationship between the functional and migratory properties of antigen-specific T cells. The current paradigm proposes that T cells follow organ-specific t...

journal_title：International archives of allergy and immunology

authors： Iparraguirre A,Weninger W

更新日期：2003-12-01 00:00:00

abstract：:We evaluated whether c-myc and ras P-21 oncogene expression could identify familial polyposis coli/Gardner's syndrome patients at risk for colon cancer. Monoclonal antibodies recognizing c-myc and ras P-21 proteins were used in immunohistochemistry to stain 26 paraffin-embedded tissue specimens collected over 12 years...

journal_title：International archives of allergy and immunology

authors： Yuwono M,Rossi TM,Fisher JE,Tjota A

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Previous studies have indicated that colitis increases intestinal permeability to food antigens. This condition also generates an immunoreactive milieu in the gut, which may exacerbate or counteract allergy reactions. This, along with the fact that both colitis and allergy are being codiagnosed more frequent...

journal_title：International archives of allergy and immunology

authors： Cueto-Sola M,Bailon E,Utrilla P,Rodríguez-Ruiz J,Garrido-Mesa N,Zarzuelo A,Xaus J,Gálvez J,Comalada M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Cannabinoid (CB) 2 is expressed on immune and inflammatory cells. Identification of 2-arachidonyl glycerol (2-AG) and anandamide as endogenous CB2 ligands has allowed investigations of the roles of CB2 and its endogenous ligand system in inflammatory cells. However, the roles of this receptor-ligand system i...

journal_title：International archives of allergy and immunology

authors： Mimura T,Oka S,Koshimoto H,Ueda Y,Watanabe Y,Sugiura T

更新日期：2012-01-01 00:00:00

abstract：:IL-13 is a relatively novel cytokine produced by activated T cells. IL-13 inhibits the production of proinflammatory cytokines and chemokines by activated monocytes, induces B cell proliferation and differentiation, including IgE production, and the expression of certain adhesion molecules on endothelial cells. All th...

journal_title：International archives of allergy and immunology

authors： de Vries JE,Zurawski G

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:The digestive system of Dermatophagoides farinae remains poorly documented. METHODS:In this study, a three-dimensional (3-D) model of the alimentary canal of D. farinae was built for the first time based on hematoxylin-eosin staining, 76 cross-sections of the adult mite and 3-D reconstruction technology. R...

journal_title：International archives of allergy and immunology

authors： Zhang YY,Sun X,Liu ZG

更新日期：2008-01-01 00:00:00

abstract：:Hypersensitivity pneumonitis remains an important industrial disease in mushroom workers. It has a significant morbidity, and early diagnosis and removal from exposure to the antigen are critically important in its management. Recently, several new allergens have been described, particularly those from mushroom specie...

journal_title：International archives of allergy and immunology

authors： Moore JE,Convery RP,Millar BC,Rao JR,Elborn JS

更新日期：2005-01-01 00:00:00

abstract：:The inhibitory effects of a novel compound, 6-hydroxy-2-(4-sulfamoylbenzylamino)-4,5,7-trimethylbenzothiazo le hydrochloride (E6080) on IgE-mediated reactions in vitro and in vivo were determined in rhesus monkeys. E6080 inhibited both antigen- and anti-human IgE-induced leukotriene C4 generations from lung fragments ...

journal_title：International archives of allergy and immunology

authors： Katayama S,Sakuma Y,Abe S,Tsunoda H,Yamatsu I,Katayama K

更新日期：1993-01-01 00:00:00