Abstract:
:Hypersensitivity pneumonitis remains an important industrial disease in mushroom workers. It has a significant morbidity, and early diagnosis and removal from exposure to the antigen are critically important in its management. Recently, several new allergens have been described, particularly those from mushroom species originating in the Far East, which are of clinical significance to workers occupationally exposed to such allergens in cultivation, picking, and packing of commercial mushroom crops. Importing of exotic mushrooms including Shiitake is common in EU countries, and some of the exotic species of mushrooms are cultivated for local markets. This practice may contribute to an increase in clinical cases of mushroom hypersensitivity pneumonitis. This update reviews the recent literature and examines changing trends of mushroom worker's lung, with increased movement of commercial product and labour markets worldwide.
journal_name
Int Arch Allergy Immunoljournal_title
International archives of allergy and immunologyauthors
Moore JE,Convery RP,Millar BC,Rao JR,Elborn JSdoi
10.1159/000083298keywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
98-102issue
1eissn
1018-2438issn
1423-0097pii
83298journal_volume
136pub_type
杂志文章,评审abstract:BACKGROUND:The aetiology of chronic urticaria is heterogeneous. Physical urticaria (PU) is estimated at around 35%, autoimmune urticaria (AIU) at 25% and chronic idiopathic urticaria (CIU) at 35% of all chronic urticaria cases. METHODS:Differences in clinical and laboratory parameters among AIU, PU and CIU groups were...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000103995
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:The Notch signaling pathway plays an important role in regulating human immune function, but the relationship between allergic rhinitis (AR) and Notch signaling remains unclear. OBJECTIVE:To investigate the role of Notch signaling in the pathogenesis of AR and its regulation on Foxp3-Treg cells. METHOD:The...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000493328
更新日期:2019-01-01 00:00:00
abstract::We examined the capacity of interleukin-4 (IL) production from lymphocytes and basophils, isolated from the peripheral blood of allergic patients sensitive to house dust mite, after stimulation with mite extract. IL-4 production was measured by a sensitive bioassay based on coculture with CT.h4S (a human IL-4-responsi...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000237375
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:Aspirin-intolerant asthma (AIA) is a clinical syndrome characterized by acute bronchoconstriction following the ingestion of aspirin. Solute carrier family 22, member 2 (SLC22A2), also known as organic cation transporter 2 (OCT2), is predominantly expressed in the luminal membrane of airway epithelial cells ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000321267
更新日期:2011-01-01 00:00:00
abstract::We studied the effect of NZ-107 in a number of animal models of anaphylactic bronchoconstriction. In conscious guinea pigs, pretreated with indomethacin, pyrilamine and propranolol, passively sensitized with heterologous anti serum, NZ-107 in doses of 10-30 mg/kg per os inhibited the aerosolized antigen-induced cough ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000236103
更新日期:1992-01-01 00:00:00
abstract::IL-13 is a relatively novel cytokine produced by activated T cells. IL-13 inhibits the production of proinflammatory cytokines and chemokines by activated monocytes, induces B cell proliferation and differentiation, including IgE production, and the expression of certain adhesion molecules on endothelial cells. All th...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章,评审
doi:10.1159/000236842
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:It has been shown that antigen presentation by resting B cells can induce tolerance to intravenously administered protein antigens, but the role of resting B cells in the induction of oral tolerance is unclear. METHODS:Mice continuously treated since birth with rabbit anti-mouse IgM serum for 5 weeks were d...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000024394
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:Galectin-9 was recently identified as a ligand for Tim-3, which negatively regulates Th1 cells. Here, we investigated whether administration of anti-galectin-9 antibodies (Abs) affects the development of murine experimental allergic conjunctivitis (EC), a Th2-mediated disease. METHODS:EC was induced in BALB...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000112501
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Natural rubber latex proteins have been implicated in severe allergy in individuals exposed to latex products, particularly health care workers. Until recently, only crude antigens were available to study the immune response in these patients. In recent years a number of relevant allergens have been purified...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000024279
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:A new lateral flow test (LFT) for office use provides information about sensitisation to common allergens. Concordance between LFT and skin-prick test (SPT) has not been assessed in epidemiological studies. The aim of this study is to determine LFT-SPT concordance in this field. METHODS:Plasma samples (n = ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000288291
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:beta2-Adrenergic agonists play a pivotal role in the management of bronchial asthma. Although the major effect of short-acting beta2-agonists on the airway is relaxation of smooth muscles, they may also have several effects on surrounding immunomodulatory cells. METHODS:We examined whether widely used short...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000089516
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Cry j 1 and Cry j 2 are thought to be the major allergens of Japanese cedar pollen. HLA class II types capable of presenting T-cell epitopes in both allergens and their role in induction of T-cell subsets are not well known. METHODS:CD4+ T (Th)-cell clones (TCCs) specific to either Cry j 1 or Cry j 2 were g...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000024194
更新日期:1999-07-01 00:00:00
abstract:BACKGROUND:Mouse models have been established mirroring key features of human bronchial asthma including airway hyperresponsiveness (AHR). Acute airway obstruction in response to an allergen challenge, however, remains to be demonstrated in these models. OBJECTIVE:A mouse model of allergic lung inflammation was employ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000024298
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:One hundred years ago, Noon [Lancet 1911;1:1572-1573], using conjunctival provocation testing (CPT), was the first to demonstrate the effectiveness of subcutaneous immunotherapy (SCIT) in grass-allergic subjects with hay fever. In this centenary year, we present data that, by use of CPT and allergen-specific...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000330649
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Disturbed cytokine production is thought to govern inflammation in asthma, which, in its turn, may lead to uncontrolled disease. The aim of this study was to assess the relationship between cytokine production from blood leucocytes and the level of asthma control. METHODS:We compared the production of inter...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000329858
更新日期:2012-01-01 00:00:00
abstract::To determine the variation of antigenic water soluble proteins in white birch (Betula pendula) pollen, extracts of pollen from different sides of individual trees were analyzed by isoelectric focusing (IEF), crossed immunoelectrophoresis, and crossed radioimmunoelectrophoresis. IgE-antibody-binding patterns were also ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000237184
更新日期:1995-12-01 00:00:00
abstract::To determine whether the costimulatory signal via CD28/B7 interaction is required for causing allergic inflammation, we examined the effect of administration of CTLA4-Ig, a fusion protein of the extracellular domain of CTLA4 and human IgG1-constant region, at the time of sensitization, on antigen-induced eosinophil in...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000053564
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:The association of pollinosis with allergy to plant foods occurs in up to 70% of tree pollen-allergic patients. In recent years, some of the relevant cross-reacting proteins have been characterized at the molecular and immunological level. Api g 1 has been identified as the celery homologue of the major birc...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000024367
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Cross-reactivity between aztreonam and β-lactams is poor, but tolerability of aztreonam has been assessed in a few groups of patients suffering from IgE-mediated allergy to β-lactams. The aim of this study was to assess the cross-reactivity of aztreonam with other β-lactams and its tolerability in patients w...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000318844
更新日期:2011-01-01 00:00:00
abstract::Most subjects without IgE to Dermatophagoides pteronyssinus do not have IgG to Der p 1 or Der p 2 (as measured by RIA). However, by immunoblot or ELISA, IgG reactivity (mostly IgG1) to mite components is easily detectable. This discrepancy is caused largely by immune reactivity to mite components with a high molecular...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000053712
更新日期:2001-01-01 00:00:00
abstract::For each medicinal product quality, safety and efficacy have to be proven to obtain a marketing authorisation. The national competent health authorities and the European Medicines Agency (EMEA) with support of the Heads of Medicines Agencies (HMA) work together to grant marketing authorisations for medicinal products....
journal_title:International archives of allergy and immunology
pub_type: 杂志文章,评审
doi:10.1159/000146074
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Mast cell tryptase has recently been reported to be involved in atherosclerotic plaque destabilization. However, the results of these reports are conflicting. METHODS:The aim of this study was to characterize the role of tryptase as a prognostic marker of patient cardiovascular complexity in acute coronary ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000360164
更新日期:2014-01-01 00:00:00
abstract::Der f2 protein in a highly antigenic form was directly expressed in bacteria. Plasmid pFLU11 derived from pKK233-2 was designed to express methionyl-Der f2 under the control of the trc promoter and it has the replication origin of pUC118 instead of its original to increase the copy number. This expression plasmid dire...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000237263
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND:Although allergy to local anesthetics (LA) is rare, patients often report unwanted reactions after their administration. A history of anaphylaxis or an atypical reaction related to LA is an indication for typing a safe anesthetic for future surgical or dental procedures. AIM:The aim of the study was to dete...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000350763
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The 2S albumins are a group of storage proteins that occur widely in seeds of dicotyledonous plants. The widespread distribution and stability to digestion of allergenic 2S albumins raise the question of why some members of this family present in important food sources, such as soybean, are not regarded as m...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000094535
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Pseudomonas aeruginosa phospholipase C (PLC) is a critical component in the pathogenesis of severe P. aeruginosa infections. However, P. aeruginosa can produce a hemolytic (PLC-H) as well as a nonhemolytic (PLC-N) variant, both having a MW of about 77 kD. In the past, studies did not distinguish between both...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000237441
更新日期:1997-02-01 00:00:00
abstract:BACKGROUND:The aim was to determine the clinical characteristics of patients with seasonal rhinitis (SR) and to disclose differences in the treatment of SR between an adult allergy clinic and other clinics over time. METHODS:A retrospective study was conducted based on clinical records of 774 out of 955 patients diagn...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000087360
更新日期:2005-09-01 00:00:00
abstract::Bed bugs may cause mild to severe cutaneous reactions. We studied the ability of bed bug salivary extract (SGE) to induce inflammatory reactions responsible for cutaneous manifestations and found that SGE stimulated the production of several potent chemokines and cytokines from macrophages. Chemokines induced by SGE i...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000345134
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Th17 is a subset of T-helper lymphocytes that produce proinflammatory cytokines, mainly IL-17. Serum IL-17 is increased in allergic patients and relates to clinical severity. Recently, it has been reported that CD161 is a highly upregulated gene in Th17 clones and all IL-17-producing cells are contained in C...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000330903
更新日期:2012-01-01 00:00:00
abstract::We investigated the effects of KW-4679, an antiallergic drug, on the development of bronchial hyperresponsiveness, airway inflammation and early and late asthmatic responses following aerosol antigen challenge in guinea pigs actively sensitized by the inhalation of aerosolized ovalbumin. Pretreatment with KW-4679 (10 ...
journal_title:International archives of allergy and immunology
pub_type: 杂志文章
doi:10.1159/000237312
更新日期:1996-05-01 00:00:00