Immunoregulatory properties of IL-13: its potential role in atopic disease.

abstract：BACKGROUND:Allergic bronchopulmonary aspergillosis (ABPA) develops in the presence of predisposing conditions such as asthma and cystic fibrosis. Even ABPA accompanied by asthma is often complicated by chronic Pseudomonas aeruginosa or nontuberculous mycobacterial infection of the lower respiratory tract, rendering tre...

journal_title：International archives of allergy and immunology

authors： Tomomatsu K,Oguma T,Baba T,Toyoshima M,Komase Y,Taniguchi M,Asano K,Japan ABPM Research Program.

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis (ACD) is an inflammatory skin disease caused by repeated skin exposure to contact allergens. The goal of this pilot study was to identify inflammatory proteins which can serve as biomarkers for ACD. METHODS:We measured levels of 102 cytokines, chemokines, and growth factors in th...

journal_title：International archives of allergy and immunology

authors： Zinkevičienė A,Kainov D,Lastauskienė E,Kvedarienė V,Bychkov D,Byrne M,Girkontaitė I

更新日期：2015-01-01 00:00:00

abstract：:Mast cell hyperplasia is found in different pathologies such as chronic inflammatory processes, fibrotic disorders, wound healing or neoplastic tissue transformation. The functional significance of the accumulation of mast cells in these processes is largely unknown. It is now established that bone marrow-derived mast...

journal_title：International archives of allergy and immunology

authors： Bischoff SC,Sellge G

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Recombinant dog allergens, rCan f 1 and rCan f 2, and their antibodies are good tools for the characterization of dog allergens in order to develop modern therapeutic and preventive methods for dog allergy. METHODS:In this study, cDNA was synthesized from the mRNA of dog salivary glands and cloned into the ...

journal_title：International archives of allergy and immunology

authors： Kamata Y,Miyanomae A,Nakayama E,Miyanomae T,Tajima T,Hoshi H

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Penicillium chrysogenum (Penicillium notatum) is a prevalent airborne Penicillium species. A 34-kD major IgE-reacting component from P. chrysogenum has been identified as an alkaline serine protease (Pen ch 13, also known as Pen n 13 before) by immunoblot and N-terminal amino acid sequence analysis. METHODS...

journal_title：International archives of allergy and immunology

authors： Chou H,Lai HY,Tam MF,Chou MY,Wang SR,Han SH,Shen HD

更新日期：2002-01-01 00:00:00

abstract：:The last decade has seen the rapid development of research investigating the mechanisms of apoptosis in a variety of experimental systems. Among the multitude of changes observed in apoptotic cells, chromatin cleavage is considered a biochemical hallmark of apoptosis. Chromatin fragmentation is an enzymatic process wh...

journal_title：International archives of allergy and immunology

authors： Zhivotovsky B,Wade D,Nicotera P,Orrenius S

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Omalizumab, an anti-immunoglobulin E (IgE) monoclonal antibody, inhibits the binding of circulating IgE to mast cells and basophils, resulting in fewer episodes of airway inflammation, asthma symptoms and exacerbations in patients with severe allergic asthma. Treatment of patients with asthma using omalizuma...

journal_title：International archives of allergy and immunology

authors： Mizuma H,Tanaka A,Uchida Y,Fujiwara A,Manabe R,Furukawa H,Kuwahara N,Fukuda Y,Kimura T,Jinno M,Ohta S,Yamamoto M,Matsukura S,Adachi M,Sagara H

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:IgE mediates immediate-type hypersensitivity reactions responsible for various allergic symptoms. It is secreted by IgE-producing plasma cells, which differentiate from B cells expressing membrane-bound IgE (mIgE) on their surface. The epsilon-chain of human mIgE contains a membrane-anchoring peptide and an ...

journal_title：International archives of allergy and immunology

authors： Chen HY,Liu FT,Hou CM,Huang JS,Sharma BB,Chang TW

更新日期：2002-08-01 00:00:00

abstract：:Patients with atopic dermatitis (AD) are frequently colonized with Staphylococcus aureus strains secreting exotoxins such as the staphylococcal enterotoxin B (SEB) and A (SEA). Nonetheless the role of SEB and SEA in AD is yet unknown. We analyzed the responsiveness of peripheral blood mononuclear cells (PBMCs) and iso...

journal_title：International archives of allergy and immunology

authors： König B,Neuber K,König W

更新日期：1995-02-01 00:00:00

abstract：:A significant increase in the incidence of allergy and asthma has been observed during the past decades. The background of this phenomenon has not been well explained, but changes in lifestyle and habits are heavily discussed as contributing factors. Among these is a too clean environment, which may predispose individ...

journal_title：International archives of allergy and immunology

authors： Zaknun D,Schroecksnadel S,Kurz K,Fuchs D

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Patients with chronic urticaria (CU) in the UK could be referred to health care professionals (HCPs) with diverse specialties using different guidelines. The aims of the present study were to determine which CU guidelines HCPs in the UK use, which tests they use for the diagnosis of CU, and how they manage C...

journal_title：International archives of allergy and immunology

authors： Wu CH,Ardern-Jones MR,Eren E,Venter C

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Data regarding the prevalence of chronic spontaneous urticaria (CSU) in childhood-onset systemic lupus erythematosus (cSLE) patients and possible associated factors are limited to a few case reports. The objectives of this study were to assess CSU in a large cSLE population, in order to evaluate the demograp...

journal_title：International archives of allergy and immunology

authors： Ferriani MP,Silva MF,Pereira RM,Terreri MT,Saad Magalhães C,Bonfá E,Pastorino AC,Carolina Dos Santos M,Appenzeller S,Ferriani VP,Len CA,Sallum AM,Libório J,Monteiro de Castro TC,Silva CA

更新日期：2015-01-01 00:00:00

abstract：:Superoxide (O2-) and nitric oxide (NO) production by polymorphonuclear leukocyte (PMNs) and monocytes in patients with liver cirrhosis were evaluated. PMNs obtained from cirrhotic patients were less effective than those from controls in producing O2- after stimulation with opsonized zymosan, while they were more effec...

journal_title：International archives of allergy and immunology

authors： Masini E,Mugnai L,Foschi M,Laffi G,Gentilini P,Mannaioni PF

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:We reported on the constitutive interferon-gamma receptor (IFN-gammaR) expression on eosinophils. But signal transduction through IFN-gammaR on eosinophils remains to be elucidated. In this study, we examined the involvement of the Jak/Stat pathway in the signaling of eosinophils after IFN-gammaR conjugation...

journal_title：International archives of allergy and immunology

authors： Ochiai K,Ishihara C,Tomioka H

更新日期：1999-02-01 00:00:00

abstract：:A quantitative determination of the inflammatory mediators was performed and correlated with complaints and the measurement of the inflammatory cells in nasal secretions of 18 seasonal allergic rhinitis patients (group 1) outside the pollen season and 40 symptomatic patients (group 2) with seasonal allergic rhinitis d...

journal_title：International archives of allergy and immunology

authors： Wang D,Clement P,Smitz J,De Waele M,Derde MP

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Pollen are monitored in Europe by a network of about 400 pollen traps, all operated manually. To date, automated pollen monitoring has only been feasible in areas with limited variability in pollen species. There is a need for rapid reporting of airborne pollen as well as for alleviating the workload of manu...

journal_title：International archives of allergy and immunology

authors： Oteros J,Pusch G,Weichenmeier I,Heimann U,Möller R,Röseler S,Traidl-Hoffmann C,Schmidt-Weber C,Buters JT

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The clinical significance and efficacy of treating patients who have immunoglobulin (Ig) G subclass deficiency and/or antibody deficiency with Ig-replacement therapy has been debated. There are no clear guidelines to recommend intravenous gammaglobulin (IgIV) in these patients as there are few published stud...

journal_title：International archives of allergy and immunology

authors： Abdou NI,Greenwell CA,Mehta R,Narra M,Hester JD,Halsey JF

更新日期：2009-01-01 00:00:00

abstract：:Antibodies to rat Thy-1, and also to murine Thy-1, could provoke reverse passive cutaneous anaphylaxis-like (RPCA-like) reactions. The threshold amount of purified anti-Thy-1 antibodies for RPCA-like reactions was 12.5 microg/ml. No RPCA-like reactions were obtained with IgG1 F(ab')2 anti-Thy-1. Cross-linking the muri...

journal_title：International archives of allergy and immunology

authors： Yamaji C,Hirano T,Miyajima H,Hashimoto H,Okumura K,Ovary Z

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:The precise roles of T helper (Th)1-type and Th2-type cytokine responses in nickel (Ni)-induced allergic contact dermatitis have not yet been clearly defined. We investigated the involvement of Th2 cytokines in Ni-induced contact hypersensitivity reaction using GATA-3 transgenic (Tg) mice. METHODS:A Ni-tita...

journal_title：International archives of allergy and immunology

authors： Niiyama S,Tamauchi H,Amoh Y,Terashima M,Matsumura Y,Kanoh M,Habu S,Komotori J,Katsuoka K

更新日期：2010-01-01 00:00:00

abstract：:Molecular mimicry between streptococci and heart components has been proposed as the triggering factor leading to autoimmunity in rheumatic heart disease (RHD). In this review, we present data from cellular autoimmune responses, focusing on the interactions between HLA class II molecules, streptococcal peptides and he...

journal_title：International archives of allergy and immunology

authors： Guilherme L,Kalil J

更新日期：2004-05-01 00:00:00

abstract：:Ovalbumin (OVA)-pullulan conjugates were made using four different conjugation methods and eight different molecular weights of pullulan ranging from 4,200 to 600,000. Pretreatment of mice by the administration of conjugates made by using cyanulic chloride or cyanogen bromide and pullulan of molecular weight 40,000 or...

journal_title：International archives of allergy and immunology

authors： Uchida T,Ikegami H,Ando S,Kurimoto M,Mitsuhashi M,Naito S,Usui M,Matuhasi T

更新日期：1993-01-01 00:00:00

abstract：:There is a great need to develop a method for making an accurate and reliable in vitro diagnosis of adverse hypersensitivity reactions to drugs. We measured the amount of sulfidoleukotriene (sLT) released from the peripheral blood leukocytes obtained from 25 patients who developed hypersensitivity reactions following ...

journal_title：International archives of allergy and immunology

authors： Kubota Y,Imayama S,Toshitani A,Miyahara H,Tanahashi T,Uemura Y,Koga T,Sugawara N,Kurimoto F,Hata K

更新日期：1997-12-01 00:00:00

abstract：INTRODUCTION:Pathologic accumulation and activation of mast cells and eosinophils are implicated in allergic and inflammatory diseases. Sialic acid-binding immunoglobulin-like lectin (Siglec)-8 is an inhibitory receptor selectively expressed on mast cells, eosinophils and, at a lower extent, basophils. When engaged wit...

journal_title：International archives of allergy and immunology

authors： Youngblood BA,Brock EC,Leung J,Falahati R,Bryce PJ,Bright J,Williams J,Shultz LD,Greiner DL,Brehm MA,Bebbington C,Tomasevic N

更新日期：2019-01-01 00:00:00

abstract：:Nitric oxide (NO) is a potent biological mediator, and has a regulatory role in a wide variety of cellular and tissue functions. In the upper and lower airways, NO has been suggested to be involved in different functions with regulatory, protective, defensive or damaging effects. It is obvious that NO plays an importa...

journal_title：International archives of allergy and immunology

authors： Sahin G,Klimek L,Mullol J,Hörmann K,Walther LE,Pfaar O

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Although common variable immunodeficiency (CVID) is associated with sinopulmonary disease, there are no previous systematic evaluations comparing computed tomographic (CT) sinus imaging with immunoglobulin measurements in patients with this condition. METHODS:We performed a retrospective review by a blinded...

journal_title：International archives of allergy and immunology

authors： Hagan JB,Park MA,Kita H,Campeau NG

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Lactation is associated with an inhibited hypothalamic-pituitary-adrenal axis response to physical and psychological stress in women and female rats. However, suckling also improved mood and calmness in nonatopic lactating women. Relaxation by humor reduced allergen-induced skin wheal responses, while variou...

journal_title：International archives of allergy and immunology

authors： Kimata H

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Jellyfish stings cause painful, papular-urticarial eruptions due to the immediate allergic, acute toxic and persistent inflammatory responses. In spite of many marine accidents and their economic impact, modes of first-aid treatment remain conventional and specific allergen and medical treatment are not yet ...

journal_title：International archives of allergy and immunology

authors： Horiike T,Nagai H,Kitani S

更新日期：2015-01-01 00:00:00

abstract：:Bronchial epithelial cells play an important role in the pathogenesis of some inflammatory diseases of bronchial mucosa. Epithelial-cell-derived cytokines are important in the elucidation of the mechanism by which airway inflammation occurs, especially in respiratory virus infection, because these cells are the primar...

journal_title：International archives of allergy and immunology

authors： Adachi M,Matsukura S,Tokunaga H,Kokubu F

更新日期：1997-05-01 00:00:00

abstract：:We investigated the effects of KW-4679, an antiallergic drug, on the development of bronchial hyperresponsiveness, airway inflammation and early and late asthmatic responses following aerosol antigen challenge in guinea pigs actively sensitized by the inhalation of aerosolized ovalbumin. Pretreatment with KW-4679 (10 ...

journal_title：International archives of allergy and immunology

authors： Ohmori K,Ishii H,Sasaki Y,Ikemura T,Manabe H,Kitamura S

更新日期：1996-05-01 00:00:00

abstract：:Recent data suggest that stem cell factor (SCF or c-kit ligand, KL) is a major regulator of human mast cells (MCs). In the present study, MCs derived from the lung (n = 8), uterus (n = 14) and heart (n = 4) were analyzed for expression of c-kit receptor and for responses to recombinant SCF. MCs of all organs tested we...

journal_title：International archives of allergy and immunology

authors： Sperr WR,Czerwenka K,Mundigler G,Müller MR,Semper H,Klappacher G,Glogar HD,Lechner K,Valent P

更新日期：1993-01-01 00:00:00