Participation of platelets in protection against larval Taenia taeniaeformis infection in mice.

abstract：BACKGROUND:It has been reported that protein tyrosine phosphorylation is essential for cytokine production in mouse Th1 cells but not in Th2 cells. However, little is known about the difference of signal transduction between human antigen-specific Th1 and Th2 cell clones. METHODS:Purified protein derivative-specific T...

journal_title：International archives of allergy and immunology

authors： Minoguchi K,Yamashita N,Oda N,Takeno M,Kaneoka H,Sakane T

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The human IgE response is associated with allergy and with host defence against parasitic worms. A response to Sm22.6, the dominant IgE antigen in adult Schistosoma mansoni worms, correlates with resistance to re-infection after treatment. Sm22.6 is one of a family of EF-hand containing parasite proteins wit...

journal_title：International archives of allergy and immunology

authors： Fitzsimmons CM,McBeath R,Joseph S,Jones FM,Walter K,Hoffmann KF,Kariuki HC,Mwatha JK,Kimani G,Kabatereine NB,Vennervald BJ,Ouma JH,Dunne DW

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The aim was to determine the clinical characteristics of patients with seasonal rhinitis (SR) and to disclose differences in the treatment of SR between an adult allergy clinic and other clinics over time. METHODS:A retrospective study was conducted based on clinical records of 774 out of 955 patients diagn...

journal_title：International archives of allergy and immunology

authors： Bozkurt B,Karakaya G,Kalyoncu AF

更新日期：2005-09-01 00:00:00

abstract：:In the classical Pavlovian conditioning paradigm, a stimulus that unconditionally elicits a physiological response is repeatedly paired with a neutral stimulus that does not elicit that same response. Eventually, the neutral stimulus becomes a conditioned stimulus in that it elicits the physiological response in the a...

journal_title：International archives of allergy and immunology

authors： Cohen N,Moynihan JA,Ader R

更新日期：1994-10-01 00:00:00

abstract：:We studied the binding activities of IgE, IgG and IgA antibodies in patients with allergy to hen's egg white against two different ovalbumin (OVA) preparations, which were physically or chemically denatured OVA and enzyme-digested OVA fragments. The binding activities of IgE antibodies to these OVA preparations with t...

journal_title：International archives of allergy and immunology

authors： Honma K,Kohno Y,Saito K,Shimojo N,Tsunoo H,Niimi H

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Asthma is a common co-morbidity of allergic rhinitis (AR). The prevalence of these two allergic diseases has increased in China and has been shown to cluster in families independently. This study evaluated the association between maternal AR (presenting with or without asthma) and the allergic conditions in ...

journal_title：International archives of allergy and immunology

authors： Wang QP,Wu KM,Li ZQ,Xue F,Chen W,Ji H,Wang BL

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Hymenoptera venom allergy (HVA) has a prevalence of 3% in adults. Although patients have no ongoing symptoms, they often suffer from an impairment of their psychological well-being and quality of life. OBJECTIVE:The aim of this study was to analyze sex-specific differences regarding the psychological burden...

journal_title：International archives of allergy and immunology

authors： Schoeben LS,Bubak C,Schaarschmidt ML,Schmieder A

更新日期：2020-01-01 00:00:00

abstract：:Transforming growth factor-beta 1 (TGF-beta(1)) is a key regulator of immune tolerance. TGF-beta(1) controls T lymphocyte activation and is involved in the immunosuppressive function and generation of regulatory T lymphocytes. Connective tissue growth factor (CTGF) has an essential role in the formation of connective ...

journal_title：International archives of allergy and immunology

authors： Kunzmann S,Seher A,Kramer BW,Schenk R,Schütze N,Jakob F,Sebald W,Speer CP

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:In developed countries, increasing food allergy prevalence and concern regarding food allergies have been reported. Although the use of complementary and alternative medicine (CAM) for the treatment of allergic diseases has increased in some Western countries, the actual proportion and patterns of CAM use fo...

journal_title：International archives of allergy and immunology

authors： Nakano T,Shimojo N,Okamoto Y,Ebisawa M,Kurihara K,Hoshioka A,Yamaguchi K,Ito K,Fujisawa T,Kameda M,Suehiro Y,Ogura H,Shibata R,Suzuki S,Takahashi Y,Ikeda M,Kohno Y

更新日期：2012-01-01 00:00:00

abstract：:Oxatomide (OXA), a histamine H1 receptor antagonist, is effective in the treatment of patients with allergic rhinitis, some allergic skin disorders, and bronchial asthma. We have characterized the effect of OXA on the immunologic release of preformed (histamine and tryptase) and de novo synthesized mediators (leukotri...

journal_title：International archives of allergy and immunology

authors： Patella V,de Crescenzo G,Marino O,Spadaro G,Genovese A,Marone G

更新日期：1996-09-01 00:00:00

abstract：:Increased serum IgE and enhanced susceptibility to viral infections, decreased levels of interferons, lymphocytic skin infiltrates and IgE-bearing epidermal Langerhans cells are striking features in patients with atopic eczema (AE). Since the hyper-IgE syndrome is known to improve under alpha-interferon (alpha-IFN) th...

journal_title：International archives of allergy and immunology

authors： Gruschwitz MS,Peters KP,Heese A,Stosiek N,Koch HU,Hornstein OP

更新日期：1993-01-01 00:00:00

abstract：:Eosinophils used to be thought of as regulators of allergic inflammation, but there is now evidence to the contrary; eosinophils have been found to be the major effector cells responsible for the late asthmatic response (LAR), airway hyperresponsiveness (AHR) and, at least in part, airway remodeling by releasing leuko...

journal_title：International archives of allergy and immunology

authors： Matsumoto K,Saito H

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:The hemagglutinin (HA) of influenza viruses is one of the major targets of the humoral response. The role of serum antibody to HA in the protection against infection has been demonstrated by long-standing observation. In previous studies, we suggested that an epitope vaccine might be a new strategy against t...

journal_title：International archives of allergy and immunology

authors： Lu Y,Ding J,Liu W,Chen YH

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Mercury causes in mouse strains of the H-2s haplotype an autoimmune syndrome with antibodies to the nucleolar protein fibrillarin and systemic immune complex (IC) deposits. Other strains, like BALB/C (H-2d), develop only IC deposits, and most strains are resistant. However, mercury activates the murine immun...

journal_title：International archives of allergy and immunology

authors： Johansson U,Hansson-Georgiadis H,Hultman P

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Interleukin (IL)-33, a new member of the IL-1 cytokine family, has been recognized as a key cytokine that enhances T helper 2-balanced immune regulation through its receptor ST2; however, the function and relationship of the IL-33 and ST2 pathways in bronchial asthma are still unclear. We investigated the ce...

journal_title：International archives of allergy and immunology

authors： Kurokawa M,Matsukura S,Kawaguchi M,Ieki K,Suzuki S,Odaka M,Watanabe S,Homma T,Sato M,Yamaguchi M,Takeuchi H,Adachi M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Sweating can worsen atopic dermatitis (AD). The purpose of this work was to study the associations between reactivity to autologous sweat and the clinical severity of AD as well as investigate the possible wheal-inducing factors of sweat. METHODS:Intracutaneous skin tests with autologous sweat were performe...

journal_title：International archives of allergy and immunology

authors： Ilves T,Virolainen A,Harvima IT

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is a multifaceted disease with a significant genetic component. The importance of taste receptor signaling has recently been highlighted in CRS; single nucleotide polymorphisms (SNPs) of bitter tastant-responsive G-protein-coupled receptors have been linked with CRS and with alte...

journal_title：International archives of allergy and immunology

authors： Purnell PR,Addicks BL,Zalzal HG,Shapiro S,Wen S,Ramadan HH,Setola V,Siderovski DP

更新日期：2019-01-01 00:00:00

abstract：:The present study has extended histochemical and functional investigations into rat mast cell heterogeneity using isolated mast cells from four connective tissue locations; the peritoneum, mesentery, lung and skin. On histological examination, mast cells from these locations displayed a range of phenotypes following f...

journal_title：International archives of allergy and immunology

authors： Tainsh KR,Pearce FL

更新日期：1992-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to evaluate the effectiveness of specific immunotherapy (SIT) management with allergoids in children with allergic asthma by monitoring changes in clinical parameters and inflammatory markers in exhaled breath. METHODS:The study population included 43 patients (24 males) of 6-14 ...

journal_title：International archives of allergy and immunology

authors： Lozano J,Cruz MJ,Piquer M,Giner MT,Plaza AM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:We showed previously that treatment with an agonistic anti-4-1BB Ab during the induction phase of murine experimental allergic conjunctivitis (EC) suppresses the development of this model disease. It was reported that 4-1BB promotes the expansion of regulatory T cells. Here we asked whether the suppression o...

journal_title：International archives of allergy and immunology

authors： Sumi T,Ishida W,Mittler RS,Yagita H,Taguchi O,Fukushima A

更新日期：2009-01-01 00:00:00

abstract：:Asthmatic individuals in the general population appear to be susceptible to disease exacerbation during summertime 'smog' episodes (ambient air pollution containing other pollutants in addition to ozone). Although controlled exposure to ozone causes acute decrements in lung function, asthmatic subjects are only margin...

journal_title：International archives of allergy and immunology

authors： Koren HS,Bromberg PA

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Clustered severe adverse reactions to immunotherapy with olive pollen extracts have been occasionally reported in areas where olive trees are extensively grown. Allergic patients from these areas, in addition to the major olive pollen allergen Ole e 1, frequently recognize a recently described allergen, Ole ...

journal_title：International archives of allergy and immunology

authors： Duffort O,Palomares O,Lombardero M,Villalba M,Barber D,Rodríguez R,Polo F

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The cytokine transforming growth factor-beta(TGF-beta) has important regulatory roles in the immune system. To investigate the role of intact TGF-beta signaling during the contact hypersensitivity (CHS) response to a respiratory allergen, we exposed Smad3-/- mice to topical trimellitic anhydride (TMA). METH...

journal_title：International archives of allergy and immunology

authors： Anthoni M,Fyhrquist N,Lehtimäki S,Alenius H,Wolff H,Lauerma A

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:IgE-mediated hypersensitivity to latex has been recognized as an increasing health problem with far-reaching consequences for patients, regarding both their occupational situation and safety in medical care. Therefore, a correct diagnosis of natural rubber latex (NRL) allergy is essential. The purpose of the...

journal_title：International archives of allergy and immunology

authors： Kütting B,Weber B,Brehler R

更新日期：2001-11-01 00:00:00

abstract：:We investigated the effects of KW-4679, an antiallergic drug, on the development of bronchial hyperresponsiveness, airway inflammation and early and late asthmatic responses following aerosol antigen challenge in guinea pigs actively sensitized by the inhalation of aerosolized ovalbumin. Pretreatment with KW-4679 (10 ...

journal_title：International archives of allergy and immunology

authors： Ohmori K,Ishii H,Sasaki Y,Ikemura T,Manabe H,Kitamura S

更新日期：1996-05-01 00:00:00

abstract：:Nitric oxide (NO) is a potent biological mediator, and has a regulatory role in a wide variety of cellular and tissue functions. In the upper and lower airways, NO has been suggested to be involved in different functions with regulatory, protective, defensive or damaging effects. It is obvious that NO plays an importa...

journal_title：International archives of allergy and immunology

authors： Sahin G,Klimek L,Mullol J,Hörmann K,Walther LE,Pfaar O

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The coexistence of asthma and allergic rhinitis (AR) and its distinct association with obesity have been reported. However, few studies have differentiated the two types of AR, i.e., perennial (PAR) and seasonal AR (SAR), with regard to their associations with asthma and obesity. The aim of this study was to...

journal_title：International archives of allergy and immunology

authors： Matsumoto M,Konno S,Kimura H,Takei N,Kimura H,Shimizu K,Goudarzi H,Suzuki M,Hashino S,Nishimura M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:While searching for antigliadin and anticasein antibodies in sera from coeliac patients we investigated more than 20 persons suffering from this enteropathy. In some of sera, we registered antibodies against gliadin and in parallel the appearance of anticasein antibodies. A high percentage of glutamic acid h...

journal_title：International archives of allergy and immunology

authors： Paranos S,Nikolic G

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:The importance of fungal allergens in the development of allergic diseases in a desert environment is uncertain. This study evaluated the prevalence of IgE sensitization to moulds among patients with allergic respiratory diseases in Kuwait - a desert country. METHODS:A total of 810 patients (male:female rat...

journal_title：International archives of allergy and immunology

authors： Ezeamuzie CI,Al-Ali S,Khan M,Hijazi Z,Dowaisan A,Thomson MS,Georgi J

更新日期：2000-04-01 00:00:00

abstract：:At an international hereditary angioedema (HAE) expert meeting, results from a survey were used to guide discussion on how best to advise patients on self-administering intravenous C1 esterase inhibitor therapy. Treatment differences across Europe were highlighted, together with the practicalities of self-administrati...

journal_title：International archives of allergy and immunology

authors： Symons C,Rossi O,Magerl M,Andritschke K

更新日期：2013-01-01 00:00:00