Immediate Wheal Reactivity to Autologous Sweat in Atopic Dermatitis Is Associated with Clinical Severity, Serum Total and Specific IgE and Sweat Tryptase Activity.

abstract：BACKGROUND:Numerous strategies have been proposed for the treatment of peanut allergies, but despite the steady advancement in our understanding of atopic immune responses and the increasing number of deaths each year from peanut anaphylaxis, there is still no safe, effective, specific therapy for the peanut-sensitive ...

journal_title：International archives of allergy and immunology

authors： Bannon GA,Cockrell G,Connaughton C,West CM,Helm R,Stanley JS,King N,Rabjohn P,Sampson HA,Burks AW

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:The role of food allergens in the induction of allergic reactions in the airways is not completely understood. The aim of the present study was to evaluate fluorocytometric assays of the peripheral blood during food challenge tests in children with asthma and food allergy. PATIENTS AND METHODS:22 children w...

journal_title：International archives of allergy and immunology

authors： Krogulska A,Wasowska-Królikowska K,Polakowska E,Chrul S

更新日期：2009-01-01 00:00:00

abstract：:Monocytes and lymphocytes from human blood contain 0.043 +/- 0.007 and 0.053 +/- 0.014 pg histamine/cell, respectively, which can be released by a number of stimulants (A 23187, C5a, substance P, specific allergen). The release process takes 60-120 min to reach its end point, in contrast to tissue mast cells which com...

journal_title：International archives of allergy and immunology

authors： Schmutzler W,Bolsmann K,Zwadlo-Klarwasser G

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Assessing high-sensitivity C-reactive protein (hs-CRP) in relation to allergic endpoints can shed light on both the mechanisms of allergic disease development and early non-communicable disease prevention. However, only a few epidemiological studies so far have investigated the relationship in children and a...

journal_title：International archives of allergy and immunology

authors： Yang BY,Markevych I,Harris C,Standl M,Schikowski T,Koletzko S,Herberth G,Bauer CP,von Berg A,Berdel D,Dong GH,Heinrich J

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The allergenic dust mite species Dermatophagoides pteronyssinus and Dermatophagoides farinae generally inhabit warm moist environments. This study tested the hypothesis that these allergenic species may thrive in air conditioner filters. METHODS:A year-long investigation of the dust mite population densitie...

journal_title：International archives of allergy and immunology

authors： Liu Z,Bai Y,Ji K,Liu X,Cai C,Yu H,Li M,Bao Y,Lian Y,Gao B

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND AIM:Although still controversial, drug provocation tests (DPTs) are considered by many as the gold standard for diagnosis of drug hypersensitivity. No studies have addressed the opinion of patients submitted to DPT. We aimed to determine patient satisfaction with diagnostic DPT and their perception of it...

journal_title：International archives of allergy and immunology

authors： Gomes ER,Kvedariene V,Demoly P,Bousquet PJ

更新日期：2011-01-01 00:00:00

abstract：:The role of CD8+ T cells in the regulation of IgE was investigated by in vivo CD8+ T-cell depletion. Following intraperitoneal immunization with ovalbumin (OVA), OVA-specific T cell responses were first detected in the draining lymph nodes (LN) and subsequently in the spleen. In vitro depletion of LN CD8+ cells reduce...

journal_title：International archives of allergy and immunology

authors： Holmes BJ,MacAry PA,Kemeny DM

更新日期：1997-05-01 00:00:00

abstract：:Profilins are ubiquitous proteins, present in all eukaryotic cells and identified as allergens in pollen, latex and plant foods. The highly conserved structure justifies the cross-reactive nature of IgE antibodies against plant profilins and their designation as pan-allergens. Primary sensitization to profilin seems t...

journal_title：International archives of allergy and immunology

authors： Santos A,Van Ree R

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Sensitivity to Chenopodiaceae is a frequent cause of allergic respiratory diseases in geographic areas where sensitization to Salsola kali and Chenopodium album has been reported. The objective of this study was to evaluate the pattern of sensitization to 3 Salsola species in patients residing on the Mediter...

journal_title：International archives of allergy and immunology

authors： Ferrer A,Larramendi CH,Huertas AJ,Pagán JA,Andreu C,García-Abujeta JL,López-Matas MA,Carnés J

更新日期：2010-01-01 00:00:00

abstract：:Fibroblast-derived growth factors like SCF are able to upregulate the expression of mast cell characteristics in human multilineage hematopoietic progenitor cells. Other factors, like GM-CSF, have been reported to inhibit this process, probably by the competitive recruitment of cells not belonging to the mast cell lin...

journal_title：International archives of allergy and immunology

authors： Welker P,Grabbe J,Zuberbier T,Henz BM

更新日期：1997-05-01 00:00:00

abstract：:A prospective study was conducted on 73 allergic patients and 14 normal volunteers in order to measure the IgE concentration in both serum and saliva, and analyze salivary IgE according to the characteristics of the allergic disease. IgE was more frequently detected in saliva from allergic patients than from normal su...

journal_title：International archives of allergy and immunology

authors： Vernejoux JM,Tunon de Lara JM,Villanueva P,Vuillemin L,Taytard A

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV) infection in infants with Th2 predisposition is thought to increase the risk of allergic sensitization, recurrent wheezing, and bronchial asthma during childhood. We attempted to clarify the molecular mechanisms by which Th1/Th2 predisposition in the host alters RSV infectio...

journal_title：International archives of allergy and immunology

authors： Yamada Y,Matsumoto K,Hashimoto N,Saikusa M,Homma T,Yoshihara S,Saito H

更新日期：2011-01-01 00:00:00

abstract：:The clear recognition that asthma has an inflammatory basis has led to a search for genetic and environmental causes. Genetic linkage studies provide evidence for allelic association between polymorphic markers of interleukin-9 on chromosome 5 and a principal component of the allergic phenotype, log IgE. Further studi...

journal_title：International archives of allergy and immunology

authors： Holgate ST,Church MK,Howarth PH,Morton EN,Frew AJ,Djukanović R

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Prostaglandin D(2) (PGD(2)), a major prostanoid produced by activated mast cells, has long been implicated in allergic diseases. PGD(2) demonstrates its effects through two G-protein-coupled receptors, DP and CRTH2. The PGD(2)/CRTH2 system mediates chemotaxis of eosinophils, basophils, and Th2 cells, which a...

journal_title：International archives of allergy and immunology

authors： Chiba T,Kanda A,Ueki S,Ito W,Kamada Y,Oyamada H,Saito N,Kayaba H,Chihara J

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Mast cell-released chemical mediators such as histamine, leukotriene (LT) C(4) and prostaglandin (PG) D(2) lead to the onset of allergic disorders. ATP provided from glycolysis is essential for histamine release and LTC(4) secretion from mast cells upon Fc epsilon RI cross-linking, indicating that glucose is...

journal_title：International archives of allergy and immunology

authors： Kitahata Y,Nunomura S,Terui T,Ra C

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Microbial components in the environment are potent activators of the immune system with capacity to shift the active immune response towards priming of Th1 and/or Th2 cells. Lipopolysaccharide (LPS), a cell-wall component of Gram-negative bacteria, is extensively present in food products like cow's milk. It ...

journal_title：International archives of allergy and immunology

authors： Brix S,Kjaer TM,Barkholt V,Frøkiaer H

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Partially hydrolyzed cow's milk protein-based formula (pHF) possesses low allergenicity. Here, we investigate the safety and efficacy of oral immunotherapy using pHF for children with cow's milk protein allergy (CMPA). OBJECTIVES:A randomized, double-blind, controlled single-center trial was conducted to ev...

journal_title：International archives of allergy and immunology

authors： Inuo C,Tanaka K,Suzuki S,Nakajima Y,Yamawaki K,Tsuge I,Urisu A,Kondo Y

更新日期：2018-01-01 00:00:00

abstract：:Nitric oxide (NO) is a potent biological mediator, and has a regulatory role in a wide variety of cellular and tissue functions. In the upper and lower airways, NO has been suggested to be involved in different functions with regulatory, protective, defensive or damaging effects. It is obvious that NO plays an importa...

journal_title：International archives of allergy and immunology

authors： Sahin G,Klimek L,Mullol J,Hörmann K,Walther LE,Pfaar O

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Hymenoptera venom allergy (HVA) has a prevalence of 3% in adults. Although patients have no ongoing symptoms, they often suffer from an impairment of their psychological well-being and quality of life. OBJECTIVE:The aim of this study was to analyze sex-specific differences regarding the psychological burden...

journal_title：International archives of allergy and immunology

authors： Schoeben LS,Bubak C,Schaarschmidt ML,Schmieder A

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Allergic reactions occur rarely in patients with chronic helminth infections, although FcepsilonRI-bearing cells are sensitized with anti-parasite IgE and are exposed to antigen. The inhibition of allergic reactivity is due to 'blocking antibodies', predominantly IgG4. IgG4 antibodies represent 50-95% of ant...

journal_title：International archives of allergy and immunology

authors： Agresti A,Vercelli D

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:While searching for antigliadin and anticasein antibodies in sera from coeliac patients we investigated more than 20 persons suffering from this enteropathy. In some of sera, we registered antibodies against gliadin and in parallel the appearance of anticasein antibodies. A high percentage of glutamic acid h...

journal_title：International archives of allergy and immunology

authors： Paranos S,Nikolic G

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Immunoglobulin G4-related disease (IgG4-RD) is a systemic immunological disorder characterized by fibro-inflammatory conditions; however, the pathobiology of IgG4-RD has not been fully identified. OBJECTIVE:This study aimed to analyze systemic differences of innate and adaptive immune cells from healthy con...

journal_title：International archives of allergy and immunology

authors： Sohn KH,Ham J,Chung SJ,Kang HR,Kim HY

更新日期：2020-01-01 00:00:00

abstract：:Based on in vitro findings with mouse mast cells and in vivo findings in mice, we report that dexamethasone or cyclosporin A can have at least three actions which interfere with the pathogenesis IgE-, mast-cell-, and cytokine-dependent inflammatory reactions: suppression of the IgE-dependent increase in tumor necrosis...

journal_title：International archives of allergy and immunology

authors： Wershil BK,Furuta GT,Lavigne JA,Choudhury AR,Wang ZS,Galli SJ

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:In naive rodents, repeated exposure to aerosolized antigen induces suppression of the Th2 response to the antigen. We hypothesized that more prolonged exposure of established asthma model to antigen aerosols may downregulate asthmatic phenotype. METHODS:After establishing an ovalbumin (OVA)-induced asthma m...

journal_title：International archives of allergy and immunology

authors： Sakai K,Yokoyama A,Kohno N,Hamada H,Hiwada K

更新日期：2001-10-01 00:00:00

abstract：:The antigenic and allergenic characteristics of three bovine epithelial extracts, dander, skin scrapings and whole skin, were compared using IgE-ELISA inhibition and SDS-PAGE with immunoblotting. Cow dander extract was shown to contain more allergenic activity than skin scrapings or whole skin extracts which were need...

journal_title：International archives of allergy and immunology

authors： Ylönen J,Mäntyjärvi R,Taivainen A,Virtanen T

更新日期：1992-01-01 00:00:00

abstract：:Phosphoinositide 3-kinases (PI3Ks) are known to be involved in a variety of cellular responses such as cell survival, proliferation, differentiation and cell migration. Recently, PI3Ks have been associated with the pathogenesis of asthma because various immune cells regulate allergic responses. Among the three classes...

journal_title：International archives of allergy and immunology

authors： Takeda M,Ito W,Tanabe M,Ueki S,Kihara J,Kato H,Tanigai T,Kayaba H,Sasaki T,Chihara J

更新日期：2010-01-01 00:00:00

abstract：:Antibodies to rat Thy-1, and also to murine Thy-1, could provoke reverse passive cutaneous anaphylaxis-like (RPCA-like) reactions. The threshold amount of purified anti-Thy-1 antibodies for RPCA-like reactions was 12.5 microg/ml. No RPCA-like reactions were obtained with IgG1 F(ab')2 anti-Thy-1. Cross-linking the muri...

journal_title：International archives of allergy and immunology

authors： Yamaji C,Hirano T,Miyajima H,Hashimoto H,Okumura K,Ovary Z

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:In some subjects, specific foods trigger anaphylaxis when exercise follows ingestion (specific food-dependent exercise-induced anaphylaxis, FDEIAn). Skin test and/or RAST positivity to foods suggest an IgE-mediated pathogenic mechanism. Others suffer from anaphylaxis after all meals followed by exercise, reg...

journal_title：International archives of allergy and immunology

authors： Romano A,Di Fonso M,Giuffreda F,Papa G,Artesani MC,Viola M,Venuti A,Palmieri V,Zeppilli P

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Recent work indicates that subcutaneous specific immunotherapy induces specific T-cell anergy, a shift in the TH1/TH2 ratio, and antibody production in favor of IgG4. There are few data on sublingual immunotherapy (SLIT), especially in children. METHODS:We assessed the proliferation of peripheral blood mono...

journal_title：International archives of allergy and immunology

authors： Rolinck-Werninghaus C,Kopp M,Liebke C,Lange J,Wahn U,Niggemann B

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DC) play a decisive role in the induction of allergen-induced Th1 and Th2 responses. Since the induction of allergen-specific Th1 responses has shown to inhibit allergen-induced Th2-type inflammation, in this study we investigated whether manipulated myeloid-derived DC pulsed with the specif...

journal_title：International archives of allergy and immunology

authors： Trujillo-Vargas CM,Ramirez-Pineda JR,Palmetshofer A,Grunewald S,Moll H,Berberich C,Erb KJ

更新日期：2005-07-01 00:00:00