Depletion of CD8+ T cells following primary immunization with ovalbumin results in a high and persistent IgE response.

abstract：BACKGROUND:ADAM (a disintegrin and metalloprotease) family members, characterized by a metalloprotease and a disintegrin domain, are membrane-anchored glycoproteins involved in proteolysis and cell adhesion. ADAM8 might have an important role in allergic inflammation. It can cleave a variety of substrates and is a shed...

journal_title：International archives of allergy and immunology

authors： Matsuno O,Miyazaki E,Nureki S,Ueno T,Ando M,Ito K,Kumamoto T,Higuchi Y

更新日期：2007-01-01 00:00:00

abstract：:To assess the role of infection in anti-DNA antibody production, the DNA-binding activity of sera from patients with Escherichia coli bacteremia was analyzed. Among 8 patients with bacteremia documented by blood culture, 5 demonstrated increased levels of antibodies to single-stranded DNA from E. coli as measured by e...

journal_title：International archives of allergy and immunology

authors： Robertson CR,Pisetsky DS

更新日期：1992-01-01 00:00:00

abstract：:Phosphoinositide 3-kinases (PI3Ks) are known to be involved in a variety of cellular responses such as cell survival, proliferation, differentiation and cell migration. Recently, PI3Ks have been associated with the pathogenesis of asthma because various immune cells regulate allergic responses. Among the three classes...

journal_title：International archives of allergy and immunology

authors： Takeda M,Ito W,Tanabe M,Ueki S,Kihara J,Kato H,Tanigai T,Kayaba H,Sasaki T,Chihara J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Cross-reactivity between aztreonam and β-lactams is poor, but tolerability of aztreonam has been assessed in a few groups of patients suffering from IgE-mediated allergy to β-lactams. The aim of this study was to assess the cross-reactivity of aztreonam with other β-lactams and its tolerability in patients w...

journal_title：International archives of allergy and immunology

authors： Buonomo A,Nucera E,De Pasquale T,Pecora V,Lombardo C,Sabato V,Colagiovanni A,Rizzi A,Aruanno A,Pascolini L,Patriarca G,Schiavino D

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Several studies have suggested that sublingual immunotherapy (SLIT) involves a dose-response relationship and inadequate dosage might not achieve a favorable clinical effect. OBJECTIVE:The aim of this prospective study was to investigate the efficacy and safety of increasing SLIT dosage at 6 months in patie...

journal_title：International archives of allergy and immunology

authors： Gao Y,Lin X,Ma J,Wei X,Wang Q,Wang M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Five to twenty percent of healthy, nonasthmatic individuals exhibit airway hyperreactivity. Because cytokines are important intermediates in airway responses, we investigated the relationship between serum cytokines and airway responsiveness in a well-characterized population of pregnant women. METHODS:We a...

journal_title：International archives of allergy and immunology

authors： Tsunoda M,Litonjua AA,Kuniak MP,Weiss ST,Satoh T,Guevarra L,Tollerud DJ

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:The digestive system of Dermatophagoides farinae remains poorly documented. METHODS:In this study, a three-dimensional (3-D) model of the alimentary canal of D. farinae was built for the first time based on hematoxylin-eosin staining, 76 cross-sections of the adult mite and 3-D reconstruction technology. R...

journal_title：International archives of allergy and immunology

authors： Zhang YY,Sun X,Liu ZG

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Data regarding the prevalence of chronic spontaneous urticaria (CSU) in childhood-onset systemic lupus erythematosus (cSLE) patients and possible associated factors are limited to a few case reports. The objectives of this study were to assess CSU in a large cSLE population, in order to evaluate the demograp...

journal_title：International archives of allergy and immunology

authors： Ferriani MP,Silva MF,Pereira RM,Terreri MT,Saad Magalhães C,Bonfá E,Pastorino AC,Carolina Dos Santos M,Appenzeller S,Ferriani VP,Len CA,Sallum AM,Libório J,Monteiro de Castro TC,Silva CA

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD) and food allergy (FA) are common childhood diseases, which may either be interrelated or be the result of skin barrier disruption and gut mucosal dysbiosis. Although some evidence suggests the efficacy of emollients and synbiotics, there is no conclusive evidence on the use of these in...

journal_title：International archives of allergy and immunology

authors： Dissanayake E,Tani Y,Nagai K,Sahara M,Mitsuishi C,Togawa Y,Suzuki Y,Nakano T,Yamaide F,Ohno H,Shimojo N

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The precise roles of T helper (Th)1-type and Th2-type cytokine responses in nickel (Ni)-induced allergic contact dermatitis have not yet been clearly defined. We investigated the involvement of Th2 cytokines in Ni-induced contact hypersensitivity reaction using GATA-3 transgenic (Tg) mice. METHODS:A Ni-tita...

journal_title：International archives of allergy and immunology

authors： Niiyama S,Tamauchi H,Amoh Y,Terashima M,Matsumura Y,Kanoh M,Habu S,Komotori J,Katsuoka K

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Mercury causes in mouse strains of the H-2s haplotype an autoimmune syndrome with antibodies to the nucleolar protein fibrillarin and systemic immune complex (IC) deposits. Other strains, like BALB/C (H-2d), develop only IC deposits, and most strains are resistant. However, mercury activates the murine immun...

journal_title：International archives of allergy and immunology

authors： Johansson U,Hansson-Georgiadis H,Hultman P

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:High antibiotic prescribing rates for adults with an asthma exacerbation have been reported in developed countries, but few studies have assessed the variation of antibiotic and adjunctive treatment in the routine care of children. OBJECTIVE:We evaluated the trends in health resource utilization for childre...

journal_title：International archives of allergy and immunology

authors： Okubo Y,Horimukai K,Michihata N,Morita K,Matsui H,Fushimi K,Yasunaga H

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Penicillium chrysogenum (Penicillium notatum) is a prevalent airborne Penicillium species. A 34-kD major IgE-reacting component from P. chrysogenum has been identified as an alkaline serine protease (Pen ch 13, also known as Pen n 13 before) by immunoblot and N-terminal amino acid sequence analysis. METHODS...

journal_title：International archives of allergy and immunology

authors： Chou H,Lai HY,Tam MF,Chou MY,Wang SR,Han SH,Shen HD

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Allergies and asthma exhibit a growing health problem in the world. Sparse data are available about the prevalence of allergic sensitization in Estonia and Eastern Europe as well. We studied the prevalence of allergic sensitization, the associations between respiratory symptoms and allergic sensitization, an...

journal_title：International archives of allergy and immunology

authors： Raukas-Kivioja A,Raukas ES,Meren M,Loit HM,Rönmark E,Lundbäck B

更新日期：2007-01-01 00:00:00

abstract：:In the last 40 years, the pathogenesis of transmissible spongiform encephalopathies of humans and animals have been the subject of exciting discoveries and also of passionate controversies. Although the human forms of these diseases are rare, the recent epidemics of bovine spongiform encephalopathy has most dramatical...

journal_title：International archives of allergy and immunology

authors： Aguzzi A

更新日期：1996-06-01 00:00:00

abstract：:Peritoneal eosinophilia was induced in rats using Ascaris suum extract as an antigen, and characteristics of granule proteins of eosinophils collected from the peritoneal cavity were investigated. Peritoneal eosinophilia was induced by injection of the antigen solution into the peritoneal cavity of the immunized rats ...

journal_title：International archives of allergy and immunology

authors： Watanabe M,Nittoh T,Suzuki T,Kitoh A,Mue S,Ohuchi K

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Studies have shown that serum total immunoglobulin E (IgE) levels are higher in asthmatics. However, the role of the serum total IgE level, independently from atopy, in adult asthma is not understood. We studied the associations between serum total IgE, the number of sensitizations and the sum of specific Ig...

journal_title：International archives of allergy and immunology

authors： Carsin AE,Zock JP,Jarvis D,Basagaña X,Heinrich J,Toren K,Janson C,Anto JM,Sunyer J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Hymenoptera venom allergy (HVA) has a prevalence of 3% in adults. Although patients have no ongoing symptoms, they often suffer from an impairment of their psychological well-being and quality of life. OBJECTIVE:The aim of this study was to analyze sex-specific differences regarding the psychological burden...

journal_title：International archives of allergy and immunology

authors： Schoeben LS,Bubak C,Schaarschmidt ML,Schmieder A

更新日期：2020-01-01 00:00:00

abstract：:Aims of the Monaco Charter: (1) to present the current evidence on the efficacy and safety of allergen-specific immunotherapy (SIT) and to address the reasons for its underuse in clinical practice; (2) to develop strategies to increase the awareness about the benefits and the hazards of SIT in allergic patients, lay p...

journal_title：International archives of allergy and immunology

authors： Canonica GW,Baena-Cagnani CE,Compalati E,Bohle B,Bonini S,Bousquet J,Cox L,Fink-Wagner AH,González Díaz S,Jacobsen L,Passalacqua G,Pawankar R,Vieths S,Yusuf O,Zuberbier T

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Diethylhexyl phthalate (DEHP) and diisononyl phthalate (DINP), two commonly used plasticizers in flexible polyvinylchloride formulations, have potentially adverse effects on human health. However, the influence of these diphthalates on allergic responses remains unclear. In this study we examined the effects...

journal_title：International archives of allergy and immunology

authors： Lee MH,Park J,Chung SW,Kang BY,Kim SH,Kim TS

更新日期：2004-07-01 00:00:00

abstract：:Many different mediators have been implicated in allergic responses and allergic diseases of the respiratory tract. The influence of several allergic inflammatory mediators on the ciliary activity has been well studied. However, ciliary responsiveness to platelet-activating factor (PAF) is yet to be established conclu...

journal_title：International archives of allergy and immunology

authors： Ohashi Y,Ohno Y,Sugiura Y,Okamoto H,Tanaka A,Kakinoki Y,Sakamoto H,Hayashi M,Nakai Y

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Sensitivity to the mite Blomia tropicalis is related to asthma in tropical climates, but correlates of sensitivity to B. tropicalis and its relationship to Dermatophagoides pteronyssinus sensitivity have not been widely examined in families with asthma. The main objective of this study was to determine preva...

journal_title：International archives of allergy and immunology

authors： Manolio TA,Barnes KC,Naidu RP,Levett PN,Beaty TH,Wilson AF

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:The classical clinical manifestation of untreated immunoglobulin deficiency comprises predominantly recurrent and complicated respiratory tract infections. Before the 1980s, little was known about the clinical manifestation of immunodeficiency in the general medical population, and also the availability of s...

journal_title：International archives of allergy and immunology

authors： Litzman J,Stikarovska D,Pikulova Z,Pavlik T,Pesak S,Thon V,Kuklinek P,Lokaj J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Chronic urticaria is associated with an immune dysregulation usually mediated by T lymphocytes. Recently, Th17 and Tc17 have been implicated in autoimmune diseases; however, their role in urticaria is not clear yet. METHODS:For the study we recruited 20 patients [10 of them had autoreactive chronic spontane...

journal_title：International archives of allergy and immunology

authors： Lopes A,Machado D,Pedreiro S,Henriques A,Silva I,Tavares B,Inácio MJ,Chieira C,Martinho A,Pais ML,Pereira C,Paiva A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:A role of bacterial superantigens in several chronic inflammatory diseases has previously been proposed. Many of these diseases are associated with an imbalance of the T helper cell subsets and their cytokine production. METHODS:Peripheral blood mononuclear cells from healthy donors were incubated with vari...

journal_title：International archives of allergy and immunology

authors： Weber AK,Wahn U,Renz H

更新日期：2000-03-01 00:00:00

abstract：:Microwave radiation from mobile phones enhanced skin wheal responses induced by house dust mite and Japanese cedar pollen while it had no effect on wheal responses induced by histamine in patients with atopic eczema/dermatitis syndrome (AEDS). Microwave radiation also increased plasma levels of substance P (SP) and va...

journal_title：International archives of allergy and immunology

authors： Kimata H

更新日期：2002-12-01 00:00:00

abstract：:Hypersensitivity pneumonitis remains an important industrial disease in mushroom workers. It has a significant morbidity, and early diagnosis and removal from exposure to the antigen are critically important in its management. Recently, several new allergens have been described, particularly those from mushroom specie...

journal_title：International archives of allergy and immunology

authors： Moore JE,Convery RP,Millar BC,Rao JR,Elborn JS

更新日期：2005-01-01 00:00:00

abstract：:We aimed to evaluate the therapeutic effect of nebulized beclomethasone dipropionate (nBDP) on both allergic asthma and rhinitis. In a randomized, double-blind, placebo-controlled study, 40 children (mean age 10.7 ± 2.1 years) with allergic asthma and rhinitis received either nBDP (daily dose of 800 µg, administered t...

journal_title：International archives of allergy and immunology

authors： Profita M,Riccobono L,Bonanno A,Chanez P,Gagliardo R,Montalbano AM,Albano GD,Liotta G,Gjomarkaj M,La Grutta S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:METHODS for predicting the clinical outcome of specific oral immunotherapy (OIT) would improve the safety of the therapy. METHODS:We investigated 40 children aged 6-17 years with IgE-mediated cow's milk allergy (CMA) who either successfully completed OIT (n = 32) or discontinued the therapy due to adverse r...

journal_title：International archives of allergy and immunology

authors： Savilahti EM,Kuitunen M,Savilahti E,Mäkelä MJ

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:We showed previously that treatment with an agonistic anti-4-1BB Ab during the induction phase of murine experimental allergic conjunctivitis (EC) suppresses the development of this model disease. It was reported that 4-1BB promotes the expansion of regulatory T cells. Here we asked whether the suppression o...

journal_title：International archives of allergy and immunology

authors： Sumi T,Ishida W,Mittler RS,Yagita H,Taguchi O,Fukushima A

更新日期：2009-01-01 00:00:00