Seasonal rhinitis, clinical characteristics and risk factors for asthma.

Abstract:

BACKGROUND:The aim was to determine the clinical characteristics of patients with seasonal rhinitis (SR) and to disclose differences in the treatment of SR between an adult allergy clinic and other clinics over time. METHODS:A retrospective study was conducted based on clinical records of 774 out of 955 patients diagnosed with SR in an adult allergy clinic between 1 January 1991 and 31 December 2003. RESULTS:The mean age of the patients was 29.1 +/- 9.29 years and 62.7% were female. The most common major complaints of the patients were nasal symptoms in 82.3%. The mean duration of the disease was 6.76 +/- 6.8 years. The patients were symptomatic with a mean of 3.5 +/- 1.7 months a year, mostly during the period between April and July. Skin prick tests were positive in 685 patients (90.3%), where the most common sensitivity was against timothy grass (85.1%). The most common accompanying allergic diseases were food hypersensitivity in 14%, bronchial asthma in 13.4%, and drug allergy and/or intolerance in 9.6%. Although the use of specific immunotherapy and short-acting sedative antihistamines decreased over time, the use of nasal steroids and long-acting nonsedative antihistamines tended to increase before admission to our clinic. Older age (OR: 1.77, 95% CI: 1.06-2.94), presence of familial atopy (OR: 1.72, 95% CI: 1.04-2.85), respiratory symptoms (OR: 2.10, 95% CI: 1.75-2.50), ocular symptoms (OR: 0.77, 95% CI: 0.61-0.98) and metal allergy (OR: 0.25, 95% CI: 0.07-0.89) were associated with the development of asthma in patients with SR. CONCLUSION:SR lasts approximately 3.5 months and the main cause in Ankara, Turkey is grass pollen sensitivity. Patients with any other allergic conditions make up 39.8% of the patients. SR patients are referred to allergy clinics quite late, which might be due to SR not being considered as a serious disease.

authors

Bozkurt B,Karakaya G,Kalyoncu AF

doi

10.1159/000087360

keywords:

subject

Has Abstract

pub_date

2005-09-01 00:00:00

pages

73-9

issue

1

eissn

1018-2438

issn

1423-0097

pii

87360

journal_volume

138

pub_type

杂志文章
  • Interaction of lymphocytes with Kupffer cells from halothane-exposed guinea pigs.

    abstract:BACKGROUND:The purpose of this study was to investigate lymphocyte adhesion to Kupffer cells as a component of an immune-mediated mechanism for halothane hepatitis. METHODS:Kupffer cells were isolated from guinea pigs exposed to 1.0% halothane/40% oxygen and cultured with various synthetic antigens (trifluoroacetyl-pr...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000237642

    authors: Furst SM,Gandolfi AJ

    更新日期:1997-09-01 00:00:00

  • N-terminus of a major allergen, Alt a I, of Alternaria alternata defined to be an epitope.

    abstract::A 20mer peptide representing the N-terminus of a major allergen, Alt a I, of Alternaria alternata was synthesized and examined for its antibody binding and antibody induction activities. Alt a I peptide-BSA conjugate reacted with both human IgE and rabbit anti-Alt a I IgG in ELISA, albeit the binding of the peptide to...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000237161

    authors: Zhang L,Curran IH,Muradia G,De Vouge MW,Rode H,Vijay HM

    更新日期:1995-11-01 00:00:00

  • On the existence of suppressor cells.

    abstract::Immunological suppression is one of the important aspects which govern the regulation of the immune response. Clonal deletion, clonal anergy and the activity of suppressor cells were proposed as mechanisms leading to this phenomenon. In this review we provide evidence for the existence of suppressor (Ts) cells and the...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章,评审

    doi:10.1159/000236379

    authors: Arnon R,Teitelbaum D

    更新日期:1993-01-01 00:00:00

  • Anti-Thy-1 antibody provokes reverse passive cutaneous anaphylaxis-like reactions.

    abstract::Antibodies to rat Thy-1, and also to murine Thy-1, could provoke reverse passive cutaneous anaphylaxis-like (RPCA-like) reactions. The threshold amount of purified anti-Thy-1 antibodies for RPCA-like reactions was 12.5 microg/ml. No RPCA-like reactions were obtained with IgG1 F(ab')2 anti-Thy-1. Cross-linking the muri...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000237662

    authors: Yamaji C,Hirano T,Miyajima H,Hashimoto H,Okumura K,Ovary Z

    更新日期:1997-10-01 00:00:00

  • The regulatory system in europe with special emphasis on allergen products.

    abstract::For each medicinal product quality, safety and efficacy have to be proven to obtain a marketing authorisation. The national competent health authorities and the European Medicines Agency (EMEA) with support of the Heads of Medicines Agencies (HMA) work together to grant marketing authorisations for medicinal products....

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章,评审

    doi:10.1159/000146074

    authors: Lorenz AR,Luttkopf D,Seitz R,Vieths S

    更新日期:2008-01-01 00:00:00

  • Enhancement of interleukin-4 production in activated CD4+ T cells by diphthalate plasticizers via increased NF-AT binding activity.

    abstract:BACKGROUND:Diethylhexyl phthalate (DEHP) and diisononyl phthalate (DINP), two commonly used plasticizers in flexible polyvinylchloride formulations, have potentially adverse effects on human health. However, the influence of these diphthalates on allergic responses remains unclear. In this study we examined the effects...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000078768

    authors: Lee MH,Park J,Chung SW,Kang BY,Kim SH,Kim TS

    更新日期:2004-07-01 00:00:00

  • Characterization of api g 1.0201, a new member of the Api g 1 family of celery allergens.

    abstract:BACKGROUND:The association of pollinosis with allergy to plant foods occurs in up to 70% of tree pollen-allergic patients. In recent years, some of the relevant cross-reacting proteins have been characterized at the molecular and immunological level. Api g 1 has been identified as the celery homologue of the major birc...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000024367

    authors: Hoffmann-Sommergruber K,Ferris R,Pec M,Radauer C,O'Riordain G,Laimer Da Camara Machado M,Scheiner O,Breiteneder H

    更新日期:2000-06-01 00:00:00

  • Deficiency in the serum-derived hyaluronan-associated protein-hyaluronan complex enhances airway hyperresponsiveness in a murine model of asthma.

    abstract:BACKGROUND:Serum-derived hyaluronan (HA)-associated proteins (SHAPs), the heavy chains of inter-α-trypsin inhibitor, covalently bind to HA to form the SHAP-HA complex. The SHAP-HA complex is involved in the pathophysiology of inflammatory diseases, including rheumatoid arthritis. We investigated whether this complex is...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000314362

    authors: Zhu L,Zhuo L,Kimata K,Yamaguchi E,Watanabe H,Aronica MA,Hascall VC,Baba K

    更新日期:2010-01-01 00:00:00

  • Immunotherapy is allergen-specific: a double-blind trial of mite or timothy extract in mite and grass dual-allergic patients.

    abstract:BACKGROUND:One hundred years ago, Noon [Lancet 1911;1:1572-1573], using conjunctival provocation testing (CPT), was the first to demonstrate the effectiveness of subcutaneous immunotherapy (SCIT) in grass-allergic subjects with hay fever. In this centenary year, we present data that, by use of CPT and allergen-specific...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000330649

    authors: Dreborg S,Lee TH,Kay AB,Durham SR

    更新日期:2012-01-01 00:00:00

  • Role of the IgE-mediated system in eosinophil recruitment triggered by two consecutive cycles of sensitisation and challenge in rats.

    abstract::In this study, we postulated that repeated cycles of IgE passive sensitisation and antigen challenge may play a role in up-regulating eosinophil response in allergic conditions. Antigen-mediated stimulation of the pleural cavity of rats passively sensitised with a single injection of IgE anti-DNP resulted in mast cell...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000049530

    authors: Calheiros AS,Aguiar Pires AL,Pereira da Silva J,Cordeiro RS,Martins MA,Lima MC

    更新日期:2001-12-01 00:00:00

  • Circadian patterns in histamine concentrations and mast cell number in the rat thyroid gland.

    abstract::We carried out a cross-sectional chronobiological investigation on blood histamine, thyroid histamine and thyroid mast cell number in Wistar rats. Daily, blood histamine varied from 0.38 +/- 0.01 (12.00 h) to 0.60 +/- 0.01 mg/g wet weight (20.00 h) and thyroid histamine from 21.2 +/- 1.19 (04.00 h) to 38.3 +/- 1.54 mg...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000236788

    authors: Catini C,Miliani A,Macchi C

    更新日期:1994-12-01 00:00:00

  • Regulation of human eotaxin generation by Th1-/Th2-derived cytokines.

    abstract:BACKGROUND:Accumulating evidence indicates that eotaxin is the primary mediator of tissue eosinophilia. In the present study, we analyzed the mechanisms of eotaxin generation by Th1-/Th2-derived cytokines in vitro. METHODS:Human dermal fibroblasts, human umbilical vein endothelial cells and A549 human bronchial epithe...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000053634

    authors: Miyamasu M,Misaki Y,Yamaguchi M,Yamamoto K,Morita Y,Matsushima K,Nakajima T,Hirai K

    更新日期:2000-05-01 00:00:00

  • An Observational Study of the Diagnosis and Management of Chronic Urticaria in the UK.

    abstract:BACKGROUND:Patients with chronic urticaria (CU) in the UK could be referred to health care professionals (HCPs) with diverse specialties using different guidelines. The aims of the present study were to determine which CU guidelines HCPs in the UK use, which tests they use for the diagnosis of CU, and how they manage C...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000430442

    authors: Wu CH,Ardern-Jones MR,Eren E,Venter C

    更新日期:2015-01-01 00:00:00

  • Molecular and cellular biology of mast cells and basophils.

    abstract::In all mammalian species investigated so far, mast cells and basophils are the only cells that synthesize histamine and express plasma membrane receptors that bind IgE with high affinity (Fc epsilonRI). Human basophils and mast cells derive from distinct precursors that originate in the bone marrow and fetal liver and...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章,评审

    doi:10.1159/000237670

    authors: Marone G,Casolaro V,Patella V,Florio G,Triggiani M

    更新日期:1997-11-01 00:00:00

  • Studies on avian spinal cord chimeras. II. Immune response of the chicken host to the graft of quail tissue.

    abstract::A previous study described clinical and pathological manifestations observed in 49 chimeras produced by replacing a small fragment of the neural tube of a chicken embryo by a similar fragment from a Japanese quail embryo. Predominant antibodies in sera of these birds were directed against xenogeneic antigens which are...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000236097

    authors: Yang G,Albini B,Milgrom F

    更新日期:1992-01-01 00:00:00

  • Peripheral blood T lymphocytes and basophils, freshly isolated from house-dust-mite-sensitive patients, produce interleukin-4 in response to allergen-specific stimulation.

    abstract::We examined the capacity of interleukin-4 (IL) production from lymphocytes and basophils, isolated from the peripheral blood of allergic patients sensitive to house dust mite, after stimulation with mite extract. IL-4 production was measured by a sensitive bioassay based on coculture with CT.h4S (a human IL-4-responsi...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000237375

    authors: Ochi H,Tanaka T,Katada Y,Naka T,Aitani M,Hashimoto S,Maeda K,Toyoshima K,Igarashi T,Suemura M,Kishimoto T

    更新日期:1996-11-01 00:00:00

  • Effect of Th1/Th2 cytokine pretreatment on RSV-induced gene expression in airway epithelial cells.

    abstract:BACKGROUND:Respiratory syncytial virus (RSV) infection in infants with Th2 predisposition is thought to increase the risk of allergic sensitization, recurrent wheezing, and bronchial asthma during childhood. We attempted to clarify the molecular mechanisms by which Th1/Th2 predisposition in the host alters RSV infectio...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000321105

    authors: Yamada Y,Matsumoto K,Hashimoto N,Saikusa M,Homma T,Yoshihara S,Saito H

    更新日期:2011-01-01 00:00:00

  • Modulation of atopy patch test and skin prick test by pretreatment with 1% pimecrolimus cream.

    abstract:BACKGROUND:In a subgroup of patients with atopic eczema (AE), aeroallergens are relevant eliciting factors. The atopy patch test (APT) was proposed as inflammation model for AE. OBJECTIVE:It was the aim of this study to investigate the effect of pretreatment with 1% pimecrolimus cream (Elidel) on the APT and skin pric...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000093249

    authors: Weissenbacher S,Traidl-Hoffmann C,Eyerich K,Katzer K,Braeutigam M,Loeffler H,Hofmann H,Behrendt H,Ring J,Darsow U

    更新日期:2006-01-01 00:00:00

  • The role of immune response to Staphylococcus aureus superantigens and disease severity in relation to the sensitivity to tacrolimus in atopic dermatitis.

    abstract:BACKGROUND:Staphylococcus aureus-producing superantigens (SAgs), such as staphylococcal enterotoxin B (SEB) or toxic shock syndrome toxin-1 (TSST-1), are frequently observed in atopic dermatitis (AD). However, little has been done to establish the association of immune responses to SAgs and the therapeutic response to ...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000095298

    authors: Fukushima H,Hirano T,Shibayama N,Miwa K,Ito T,Saito M,Sumida H,Oyake S,Tsuboi R,Oka K

    更新日期:2006-01-01 00:00:00

  • The synthetic PPARgamma agonist troglitazone inhibits eotaxin-enhanced eosinophil adhesion to ICAM-1-coated plates.

    abstract::Accumulation and activation of eosinophils in tissue are critical events in the allergic inflammatory response and adhesion molecules play important roles in this process. We previously demonstrated that human eosinophils expressed a nuclear receptor, peroxisome proliferator-activated receptor gamma (PPARgamma), and t...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000126054

    authors: Hirasawa H,Chiba T,Ueki S,Kamada Y,Ito W,Takeda M,Fujita M,Kato H,Kayaba H,Chihara J

    更新日期:2008-01-01 00:00:00

  • Classification of Drug Hypersensitivity into Allergic, p-i, and Pseudo-Allergic Forms.

    abstract::Drug hypersensitivity reactions (DHR) are clinically and functionally heterogeneous. Different subclassifications based on timing of symptom appearance or type of immune mechanism have been proposed. Here, we show that the mode of action of drugs leading to immune/inflammatory cell stimulation is a further decisive fa...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章,评审

    doi:10.1159/000453265

    authors: Pichler WJ,Hausmann O

    更新日期:2016-01-01 00:00:00

  • Chronic Spontaneous Urticaria: A Survey of 852 Cases of Childhood-Onset Systemic Lupus Erythematosus.

    abstract:BACKGROUND:Data regarding the prevalence of chronic spontaneous urticaria (CSU) in childhood-onset systemic lupus erythematosus (cSLE) patients and possible associated factors are limited to a few case reports. The objectives of this study were to assess CSU in a large cSLE population, in order to evaluate the demograp...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000438723

    authors: Ferriani MP,Silva MF,Pereira RM,Terreri MT,Saad Magalhães C,Bonfá E,Pastorino AC,Carolina Dos Santos M,Appenzeller S,Ferriani VP,Len CA,Sallum AM,Libório J,Monteiro de Castro TC,Silva CA

    更新日期:2015-01-01 00:00:00

  • Molecular and immunological characteristics of latex allergens.

    abstract::Natural rubber latex proteins are a well-recognized cause of type-I allergic reactions that increasingly afflict health-care workers, housekeeping personnel, and other persons using latex gloves or latex products. More than a dozen individual latex allergens have been identified of which eight have received an interna...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章,评审

    doi:10.1159/000023930

    authors: Breiteneder H,Scheiner O

    更新日期:1998-06-01 00:00:00

  • Unexpected functions of FcepsilonRI on antigen-presenting cells.

    abstract::In contrast to mast cells and basophils, the high affinity IgE receptor (FcepsilonRI) on antigen-presenting cells (APC) shows structural and functional differences. It consists only of a minimal structure of one alpha- and two gamma-chains and enables APC to efficiently take up and present antigen in IgE-mediated dela...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章,评审

    doi:10.1159/000053662

    authors: Kraft S,Katoh N,Novak N,Koch S,Bieber T

    更新日期:2001-01-01 00:00:00

  • The human IgE repertoire.

    abstract::IgE is a key mediator in allergic diseases. However, in strong contrast to other antibody isotypes, many details of the composition of the human IgE repertoire are poorly defined. The low levels of human IgE in the circulation and the rarity of IgE-producing B cells are important reasons for this lack of knowledge. In...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章,评审

    doi:10.1159/000355947

    authors: Gadermaier E,Levin M,Flicker S,Ohlin M

    更新日期:2014-01-01 00:00:00

  • CD44 expression on blood eosinophils is a novel marker of bronchial asthma.

    abstract::Bronchial asthma is characterized by infiltration of the respiratory tracts by eosinophils. A wide variety of adhesion molecules expressed by eosinophils have been proposed to be involved in binding of eosinophils to the vascular endothelium and subsequent transmigration from the circulation to the airways, while litt...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000237722

    authors: Sano K,Yamauchi K,Hoshi H,Honma M,Tamura G,Shirato K

    更新日期:1997-10-01 00:00:00

  • The intestinal intraepithelial lymphocytes with t cell receptor alphabeta express toll-like receptor 4 and are responsive to lipopolysaccharide.

    abstract:BACKGROUND:Intestinal intraepithelial lymphocytes (iIELs) play an important role in intestinal innate immunity and oral immune tolerance. To compare the differences in gene expression between murine iIELs and splenic T lymphocytes, we established the cDNA subtractive library of iIELs and analyzed the iIELs special gene...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000095468

    authors: Ma C,Xu C,Duan L,He W

    更新日期:2006-01-01 00:00:00

  • Soluble CD23 levels are inversely associated with atopy and parasite-specific IgE levels but not with polyclonal IgE levels in people exposed to helminth infection.

    abstract:BACKGROUND:Protective acquired immunity against helminths and allergic sensitisation are both characterised by high IgE antibody levels. Levels of IgE antibodies are naturally tightly regulated by several mechanisms including binding of the CD23 receptor. Following observations that helminth infections and allergic sen...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000346545

    authors: Rujeni N,Nausch N,Midzi N,Gwisai R,Mduluza T,Taylor DW,Mutapi F

    更新日期:2013-01-01 00:00:00

  • Presence of bronchoalveolar lavage fluid necessary for platelet activating factor-induced ciliary depression.

    abstract::Many different mediators have been implicated in allergic responses and allergic diseases of the respiratory tract. The influence of several allergic inflammatory mediators on the ciliary activity has been well studied. However, ciliary responsiveness to platelet-activating factor (PAF) is yet to be established conclu...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000236681

    authors: Ohashi Y,Ohno Y,Sugiura Y,Okamoto H,Tanaka A,Kakinoki Y,Sakamoto H,Hayashi M,Nakai Y

    更新日期:1994-07-01 00:00:00

  • Optimizing the use of a skin prick test device on children.

    abstract:BACKGROUND:Studies comparing skin prick test (SPT) devices have revealed varying results in performance and there is little known about their use on children. METHODS:We performed 2 complementary studies to test the sensitivity, reproducibility and acceptability of commercially available SPT devices (Stallerpoint, Ant...

    journal_title:International archives of allergy and immunology

    pub_type: 杂志文章

    doi:10.1159/000350788

    authors: Buyuktiryaki B,Sahiner UM,Karabulut E,Cavkaytar O,Tuncer A,Sekerel BE

    更新日期:2013-01-01 00:00:00