Modulation of atopy patch test and skin prick test by pretreatment with 1% pimecrolimus cream.

abstract：BACKGROUND:Epinephrine autoinjector (EAI) is prescribed to prevent a fatal outcome in the case of a repeated anaphylactic reactions. We wanted to determine how adult patients who received their first prescription as part of an urgent treatment of an anaphylactic reaction or at their family physician were instructed on ...

journal_title：International archives of allergy and immunology

authors： Kadivec S,Košnik M

更新日期：2021-01-22 00:00:00

abstract：BACKGROUND:The so-called 'latex-fruit syndrome' is a well-documented phenomenon in cross-reactive allergies. By contrast, there is a lack of information about allergy to exotic fruits in patients with a predominant pollen sensitization. Since the ubiquitous protein profilin has been identified as an allergen in natural...

journal_title：International archives of allergy and immunology

authors： Reindl J,Rihs HP,Scheurer S,Wangorsch A,Haustein D,Vieths S

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Asthma is a major health problem worldwide, and the morbidity and mortality caused by asthma are on the rise. Corticosteroid therapies for asthma treatment frequently induce many side effects. Therefore, the development of new medicines that have both high efficacy and fewer side effects has been a scientifi...

journal_title：International archives of allergy and immunology

authors： Lim YJ,Na HS,Yun YS,Choi IS,Oh JS,Rhee JH,Cho BH,Lee HC

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori, the main cause of gastritis and peptic ulcer, has been associated with idiopathic chronic urticaria (ICU), an immunological skin disorder of unknown origin. Eosinophilic cationic protein (ECP) is a cytotoxic molecule secreted by the activated eosinophils involved in the pathogenesis of I...

journal_title：International archives of allergy and immunology

authors： Ojetti V,Armuzzi A,De Luca A,Nucera E,Franceschi F,Candelli M,Zannoni GF,Danese S,Di Caro S,Vastola M,Schiavino D,Gasbarrini G,Patriarca G,Pola P,Gasbarrini A

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Severe asthma is a heterogeneous disease, which is characterized by airway damage and remodeling. All triggers of asthma, such as allergens, bacteria, viruses, and pollutants, interact with the airway epithelial cells, which drive the airway inflammatory response through the release of cytokines, particularl...

journal_title：International archives of allergy and immunology

authors： Boita M,Heffler E,Omedè P,Bellocchia M,Bussolino C,Solidoro P,Giorgis V,Guerrera F,Riva G,Brussino L,Bucca C,Rolla G

更新日期：2018-01-01 00:00:00

abstract：:Owing to the proposed role of Fc epsilon RII/CD23 in allergic diseases, we analyzed the expression of this receptor on peripheral blood lymphocytes (pan-B, pan-T and CD4+ or CD8+ T cells) and its autoproteolytic product sCD23 in serum. This was done in 10 asthmatic children allergic to Dermatophagoides pteronyssinus (...

journal_title：International archives of allergy and immunology

authors： Gagro A,Rabatić S,Tresćec A,Dekaris D,Medar-Lasić M

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:T(H)2 inflammation and bronchial smooth muscle cell (BSMC) hyperplasia are characteristic features of asthma, but whether these phenomena are linked remains unknown. This study aims to define the effect of the T(H)2 cytokines IL-4 and IL-13 on human BSMC proliferation when administered alone or in combinatio...

journal_title：International archives of allergy and immunology

authors： Bossé Y,Thompson C,Audette K,Stankova J,Rola-Pleszczynski M

更新日期：2008-01-01 00:00:00

abstract：:Oxatomide (OXA), a histamine H1 receptor antagonist, is effective in the treatment of patients with allergic rhinitis, some allergic skin disorders, and bronchial asthma. We have characterized the effect of OXA on the immunologic release of preformed (histamine and tryptase) and de novo synthesized mediators (leukotri...

journal_title：International archives of allergy and immunology

authors： Patella V,de Crescenzo G,Marino O,Spadaro G,Genovese A,Marone G

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Nitrosative and acid stress play an important role in the pathogenesis of asthma. The aim of this study was to evaluate whether, in asthmatics, a link exists between the concentrations of nitrite/nitrate, ammonia and pH values in exhaled breath condensate (EBC) and asthma severity, lung function, exhaled nit...

journal_title：International archives of allergy and immunology

authors： Tomasiak-Lozowska MM,Zietkowski Z,Przeslaw K,Tomasiak M,Skiepko R,Bodzenta-Lukaszyk A

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Jellyfish stings cause painful, papular-urticarial eruptions due to the immediate allergic, acute toxic and persistent inflammatory responses. In spite of many marine accidents and their economic impact, modes of first-aid treatment remain conventional and specific allergen and medical treatment are not yet ...

journal_title：International archives of allergy and immunology

authors： Horiike T,Nagai H,Kitani S

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:A growing body of evidence suggests that proinflammatory cytokines play a role in allergic inflammation by attracting and activating inflammatory cells. In this study, we have investigated the relationship between interleukin-8 (IL-8) in nasal lavage fluid and the local activation of eosinophils and neutroph...

journal_title：International archives of allergy and immunology

authors： Jacobi HH,Poulsen LK,Reimert CM,Skov PS,Ulfgren AK,Jones I,Elfman LB,Malling HJ,Mygind N

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Serum-derived hyaluronan (HA)-associated proteins (SHAPs), the heavy chains of inter-α-trypsin inhibitor, covalently bind to HA to form the SHAP-HA complex. The SHAP-HA complex is involved in the pathophysiology of inflammatory diseases, including rheumatoid arthritis. We investigated whether this complex is...

journal_title：International archives of allergy and immunology

authors： Zhu L,Zhuo L,Kimata K,Yamaguchi E,Watanabe H,Aronica MA,Hascall VC,Baba K

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Human leukocyte antigen G (HLA-G) is a nonclassical major histocompatibility complex class I gene. HLA-G stimulates Th2 cytokine secretion by peripheral blood mononuclear cells. The role of soluble HLA-G (sHLA-G) in bronchial asthma is incompletely understood and the plasma level of sHLA-G in asthmatic child...

journal_title：International archives of allergy and immunology

authors： Tahan F,Patiroglu T

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Oxidants including reactive oxygen species have been indicated to play an important role in the pathogenesis of asthma. OBJECTIVE:We investigated oxidative status in patients with acute exacerbations of asthma and evaluated the therapeutic response using the D-ROM test which is simple to use and quick. MET...

journal_title：International archives of allergy and immunology

authors： Suzuki S,Matsukura S,Takeuchi H,Kawaguchi M,Ieki K,Odaka M,Watanabe S,Homma T,Dohi K,Aruga T,Sato M,Kurokawa M,Kokubu F,Adachi M

更新日期：2008-01-01 00:00:00

abstract：:The present study has extended histochemical and functional investigations into rat mast cell heterogeneity using isolated mast cells from four connective tissue locations; the peritoneum, mesentery, lung and skin. On histological examination, mast cells from these locations displayed a range of phenotypes following f...

journal_title：International archives of allergy and immunology

authors： Tainsh KR,Pearce FL

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Recently, the relationship between antigen contact via skin (skin sensitization) and the development of food allergies has gained increasing attention. However, few studies have examined the effects of skin sensitization on healthy skin. OBJECTIVE:To examine the effect of sensitization in healthy skin on Ig...

journal_title：International archives of allergy and immunology

authors： Koshiba R,Oba T,Fuwa A,Arai K,Sasaki N,Kitazawa G,Hattori M,Matsuda H,Yoshida T

更新日期：2020-11-11 00:00:00

abstract：:Thymulin is a nonapeptide hormone isolated from the thymus gland. It has immunomodulatory effects which have not yet been well defined. Its major actions have been shown to be on T-cells and their immature precursors. In this study, thymulin was tested in vitro for its effect on the release of IL-1 alpha, IL-2, IL-6 a...

journal_title：International archives of allergy and immunology

authors： Safieh-Garabedian B,Ahmed K,Khamashta MA,Taub NA,Hughes GR

更新日期：1993-01-01 00:00:00

abstract：:It has been well documented that environmental factors such as antigen-presenting cells and related cytokines can affect the development of T-helper cells. The purpose of this study was to investigate the role of different antigen-presenting cells on T-cell development. Ovalbumin (OVA) combined with complete Freud's a...

journal_title：International archives of allergy and immunology

authors： Chuang YH,Chiang BL,Chou CC,Hsieh KH

更新日期：1996-12-01 00:00:00

abstract：:Aerosolized monoclonal antibodies (mAbs) specific for T-cell receptors (TCR) were used to manipulate T-cell function in airways of ovalbumin (OVA)-sensitized and -challenged mice with airway hyperresponsiveness (AHR). The inhaled mAbs were found to be effective at low doses, had little or no systemic effect and specif...

journal_title：International archives of allergy and immunology

authors： Lahn M,Kanehiro A,Hahn YS,Wands JM,Aydintug MK,O'Brien RL,Gelfand EW,Born WK

更新日期：2004-05-01 00:00:00

abstract：:Phosphoinositide 3-kinases (PI3Ks) are known to be involved in a variety of cellular responses such as cell survival, proliferation, differentiation and cell migration. Recently, PI3Ks have been associated with the pathogenesis of asthma because various immune cells regulate allergic responses. Among the three classes...

journal_title：International archives of allergy and immunology

authors： Takeda M,Ito W,Tanabe M,Ueki S,Kihara J,Kato H,Tanigai T,Kayaba H,Sasaki T,Chihara J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Exposure and sensitization to indoor allergens have been associated with the development of asthma and other allergic diseases in many parts of the world. It is important to establish the degree of exposure, and to evaluate whether allergen control measures are effective in a particular area. METHODS:Concen...

journal_title：International archives of allergy and immunology

authors： Tobias KR,Ferriani VP,Chapman MD,Arruda LK

更新日期：2004-04-01 00:00:00

abstract：:The inhibitory effects of a novel compound, 6-hydroxy-2-(4-sulfamoylbenzylamino)-4,5,7-trimethylbenzothiazo le hydrochloride (E6080) on IgE-mediated reactions in vitro and in vivo were determined in rhesus monkeys. E6080 inhibited both antigen- and anti-human IgE-induced leukotriene C4 generations from lung fragments ...

journal_title：International archives of allergy and immunology

authors： Katayama S,Sakuma Y,Abe S,Tsunoda H,Yamatsu I,Katayama K

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:We have previously shown that human monocyte-derived dendritic cells (moDCs) may participate in immune system-mediated hypercoagulable state through enhanced tissue factor (TF) expression and that the complement system may be involved in this process. OBJECTIVES:The aim of this study was to explore the role...

journal_title：International archives of allergy and immunology

authors： Kasuda S,Sakurai Y,Tatsumi K,Takeda T,Kudo R,Yuui K,Hatake K

更新日期：2019-01-01 00:00:00

abstract：AIM:We evaluated the effect of the 45-kD protein of Trichinella spiralis (gp45), purified by affinity chromatography, on random migration and chemotaxis, the oxidative metabolism of human neutrophils and on the CD11b upregulation induced by formyl-methionyl-leucyl-phenylalanine (f-MLP). METHODS:Donor neutrophils incub...

journal_title：International archives of allergy and immunology

authors： Bruschi F,Carulli G,Azzarà A,Homan W,Minnucci S,Rizzuti-Gullaci A,Sbrana S,Angiolini C

更新日期：2000-05-01 00:00:00

abstract：:Molecular mimicry between streptococci and heart components has been proposed as the triggering factor leading to autoimmunity in rheumatic heart disease (RHD). In this review, we present data from cellular autoimmune responses, focusing on the interactions between HLA class II molecules, streptococcal peptides and he...

journal_title：International archives of allergy and immunology

authors： Guilherme L,Kalil J

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Studies comparing skin prick test (SPT) devices have revealed varying results in performance and there is little known about their use on children. METHODS:We performed 2 complementary studies to test the sensitivity, reproducibility and acceptability of commercially available SPT devices (Stallerpoint, Ant...

journal_title：International archives of allergy and immunology

authors： Buyuktiryaki B,Sahiner UM,Karabulut E,Cavkaytar O,Tuncer A,Sekerel BE

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Autoimmune disorders are considered to be associated with a Th1 immune response while allergic diseases with a Th2 response. We carried out a study to determine whether there is an inverse relationship between allergic diseases in IgE-sensitized children or positive skin-prick test reactions to allergens and...

journal_title：International archives of allergy and immunology

authors： Caffarelli C,Cavagni G,Pierdomenico R,Chiari G,Spattini A,Vanelli M

更新日期：2004-08-01 00:00:00

abstract：:Thioredoxin (TRX) is a redox-active protein that regulates reactive oxidative metabolism and plays a crucial role in the antioxidant system in regulating the reduction/oxidation balance by scavenging reactive oxygen species, which is implicated in the mechanism of asthma. As for the mechanisms by which TRX exerts its ...

journal_title：International archives of allergy and immunology

authors： Ito W,Kobayashi N,Takeda M,Ueki S,Kayaba H,Nakamura H,Yodoi J,Chihara J

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Adoptive transfer of helper T (Th) cells conferred a late asthmatic response upon antigen challenge. A possible production of a contractile activity for bronchial smooth muscle (BSM) by activated Th cells was examined. METHOD:Murine Th clones were stimulated with immobilized anti-CD3 antibody in the presenc...

journal_title：International archives of allergy and immunology

authors： Abe A,Koyama S,Ohtomo T,Kitamura N,Kaminuma O,Mori A

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to evaluate the effectiveness of specific immunotherapy (SIT) management with allergoids in children with allergic asthma by monitoring changes in clinical parameters and inflammatory markers in exhaled breath. METHODS:The study population included 43 patients (24 males) of 6-14 ...

journal_title：International archives of allergy and immunology

authors： Lozano J,Cruz MJ,Piquer M,Giner MT,Plaza AM

更新日期：2014-01-01 00:00:00