Studies on avian spinal cord chimeras. II. Immune response of the chicken host to the graft of quail tissue.

abstract：BACKGROUND:Serum-derived hyaluronan (HA)-associated proteins (SHAPs), the heavy chains of inter-α-trypsin inhibitor, covalently bind to HA to form the SHAP-HA complex. The SHAP-HA complex is involved in the pathophysiology of inflammatory diseases, including rheumatoid arthritis. We investigated whether this complex is...

journal_title：International archives of allergy and immunology

authors： Zhu L,Zhuo L,Kimata K,Yamaguchi E,Watanabe H,Aronica MA,Hascall VC,Baba K

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Over the past years, dust of green coffee beans has become known to be a relevant cause for occupational type I allergies. Up to now, allergy diagnostics is based on native green coffee bean extract which exhibits insufficient specificity due to interfering substances as well as batch-to-batch variations. No...

journal_title：International archives of allergy and immunology

authors： Manavski N,Peters U,Brettschneider R,Oldenburg M,Baur X,Bittner C

更新日期：2012-01-01 00:00:00

abstract：:There is increasing evidence that the asthma process is 'driven' and maintained by persistence of a subset of chronically activated T memory cells, sensitized against allergenic, occupational or viral antigens which 'home' to the lung after antigen exposure or viral infection. In general, allergens induce a CD4 T help...

journal_title：International archives of allergy and immunology

authors： Kon OM,Kay AB

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Th17 is a subset of T-helper lymphocytes that produce proinflammatory cytokines, mainly IL-17. Serum IL-17 is increased in allergic patients and relates to clinical severity. Recently, it has been reported that CD161 is a highly upregulated gene in Th17 clones and all IL-17-producing cells are contained in C...

journal_title：International archives of allergy and immunology

authors： Poggi A,Canevali P,Contatore M,Ciprandi G

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Lactobacillus casei is a nonpathogenic gram-positive bacterium widely used in dairy products and has been shown to enhance the cellular immunity of the host. METHODS:To examine the inhibitory effect of L. casei on IgE production, splenocytes obtained from ovalbumin (OVA)-primed BALB/c mice were restimulated...

journal_title：International archives of allergy and immunology

authors： Shida K,Makino K,Morishita A,Takamizawa K,Hachimura S,Ametani A,Sato T,Kumagai Y,Habu S,Kaminogawa S

更新日期：1998-04-01 00:00:00

abstract：:Guinea pigs were sensitized with 2,4-toluene diisocyanate (TDI) by a repetitive application onto the bilateral nasal vestibules once a day for 5 consecutive days. When these animals were further treated with TDI for additional 9 weeks, a number of these animals exhibited external symptoms similar to those in human ast...

journal_title：International archives of allergy and immunology

authors： Sugawara Y,Okamoto Y,Sawahata T,Tanaka K

更新日期：1993-01-01 00:00:00

abstract：UNLABELLED:T-bet is crucially implicated in Th1 differentiation due to its strong promoting activity for IFN-gamma gene transcription. However, the regulatory role of T-bet in Th2 cytokines is not fully delineated. METHODS:The effect of T-bet on mRNA expression as well as the promoter activity of IL-4 in human T cells...

journal_title：International archives of allergy and immunology

authors： Kitamura N,Kitamura F,Kaminuma O,Miyatake S,Tatsumi H,Nemoto S,Mori A

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:House dust mite (HDM)-sensitive allergic rhinitis is a perennial rhinitis with persistent nasal inflammation. Currently, there are no reliable parameters to monitor the severity of perennial allergic rhinitis. The purpose of this study was to evaluate correlations between clinical and laboratory parameters i...

journal_title：International archives of allergy and immunology

authors： Klaewsongkram J,Ruxrungtham K,Wannakrairot P,Ruangvejvorachai P,Phanupak P

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:We have previously shown that the allergic sensitization to ovalbumin does not represent a superantigen-like immune response. In gene-targeted mice (ΔD-iD) with a single modified Diversity gene segment (D(H)) of the immunoglobulin heavy chain, enriched for charged amino acids, the asthma phenotype in a murin...

journal_title：International archives of allergy and immunology

authors： Kerzel S,Rogosch T,Wagner J,Preisser K,Yildirim AÖ,Fehrenbach H,Garn H,Maier RF,Schroeder HW Jr,Zemlin M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The cytokine transforming growth factor-beta(TGF-beta) has important regulatory roles in the immune system. To investigate the role of intact TGF-beta signaling during the contact hypersensitivity (CHS) response to a respiratory allergen, we exposed Smad3-/- mice to topical trimellitic anhydride (TMA). METH...

journal_title：International archives of allergy and immunology

authors： Anthoni M,Fyhrquist N,Lehtimäki S,Alenius H,Wolff H,Lauerma A

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Egg allergy is one of the most common food allergies in children. The standard therapy for egg allergy is strict avoidance. Yet, there is considerable clinical and scientific interest in primary or secondary prevention. A major drawback of oral tolerance (OT) induction protocols, however, is the possibility ...

journal_title：International archives of allergy and immunology

authors： Hacini-Rachinel F,Vissers YM,Doucet-Ladevéze R,Blanchard C,Demont A,Perrot M,Panchaud A,Prioult G,Mercenier A,Nutten S

更新日期：2014-01-01 00:00:00

abstract：:We isolated a major wheat flour allergen with a molecular weight of 15-kD. The 15-kD allergen was purified from an extract of wheat flour by ammonium sulfate precipitation followed by gel filtration. Using the immunoblot technique, IgE, specifically directed towards the single isolated allergen, was detectable in 50% ...

journal_title：International archives of allergy and immunology

authors： Fränken J,Stephan U,Meyer HE,König W

更新日期：1994-01-01 00:00:00

abstract：:IgE responsiveness to Dermatophagoides farinae body extract was compared by immunoblotting among four groups of mite-sensitive asthmatic children: group I aged 0-3, group II aged 4-7, group III aged 8-11 and group IV aged 12-15. In the group I subjects, the 15-kD component was bound by 88% of sera and strongly by 56% ...

journal_title：International archives of allergy and immunology

authors： Shibasaki M,Isoyama S,Takita H

更新日期：1994-01-01 00:00:00

abstract：:Two cDNA clones named P9* and P1* of 794 and 631 bp, respectively, were isolated from a lambda ZAP cDNA expression library using Parietaria judaica (Pj) pollen-specific IgE antibodies from a pool of sera (n = 23) of patients allergic to Pj. Sequence analysis showed open reading frames of 176 and 138 amino acids. Both ...

journal_title：International archives of allergy and immunology

authors： Duro G,Colombo P,Assunta Costa M,Izzo V,Porcasi R,Di Fiore R,Locorotondo G,Cocchiara R,Geraci D

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Allergic reactions occur rarely in patients with chronic helminth infections, although FcepsilonRI-bearing cells are sensitized with anti-parasite IgE and are exposed to antigen. The inhibition of allergic reactivity is due to 'blocking antibodies', predominantly IgG4. IgG4 antibodies represent 50-95% of ant...

journal_title：International archives of allergy and immunology

authors： Agresti A,Vercelli D

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Patients with allergic rhinoconjunctivitis are susceptible to both nasal and ocular symptoms. The conjunctival provocation test (CPT) is an established diagnostic procedure used in allergic rhinoconjunctivitis, particularly to document a patient's current reactivity to allergens. To date, there are no intern...

journal_title：International archives of allergy and immunology

authors： Dogan S,Astvatsatourov A,Deserno TM,Bock F,Shah-Hosseini K,Michels A,Mösges R

更新日期：2014-01-01 00:00:00

abstract：:Microwave radiation from mobile phones enhanced skin wheal responses induced by house dust mite and Japanese cedar pollen while it had no effect on wheal responses induced by histamine in patients with atopic eczema/dermatitis syndrome (AEDS). Microwave radiation also increased plasma levels of substance P (SP) and va...

journal_title：International archives of allergy and immunology

authors： Kimata H

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Allergen molecule-based diagnosis has been suggested to facilitate the identification of disease-causing allergen sources and the prescription of allergen-specific immunotherapy (AIT). The aim of the current study was to compare allergen molecule-based IgE serology with allergen extract-based skin testing fo...

journal_title：International archives of allergy and immunology

authors： Saltabayeva U,Garib V,Morenko M,Rosenson R,Ispayeva Z,Gatauova M,Zulus L,Karaulov A,Gastager F,Valenta R

更新日期：2017-01-01 00:00:00

abstract：:Peritoneal mast cells of Syrian hamsters release histamine to the action of concanavalin A (Con A) in dose-dependent fashion. The rate of release was very rapid in the first seconds of cell activation and completed in 60 s after the challenge. Morphological changes concomitant to the lectin treatment, followed by elec...

journal_title：International archives of allergy and immunology

authors： Wyczolkowska J,Rydzynski K,Prouvost-Danon A

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Protective acquired immunity against helminths and allergic sensitisation are both characterised by high IgE antibody levels. Levels of IgE antibodies are naturally tightly regulated by several mechanisms including binding of the CD23 receptor. Following observations that helminth infections and allergic sen...

journal_title：International archives of allergy and immunology

authors： Rujeni N,Nausch N,Midzi N,Gwisai R,Mduluza T,Taylor DW,Mutapi F

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Evidence regarding sublingual immunotherapy (SLIT) efficacy and its good safety profile has been demonstrated with pollen and house dust mite (HDM) allergens in the treatment of airway allergies. In addition, the use of grass pollen presents a SLIT disease-modifying treatment for respiratory allergies. OBJE...

journal_title：International archives of allergy and immunology

authors： Hagner S,Rask C,Brimnes J,Andersen PS,Raifer H,Renz H,Garn H

更新日期：2016-01-01 00:00:00

abstract：:Preferential eosinophil accumulation is characteristic of airway inflammation in asthma. Although little is known about its mechanism, the effect of a sialyl Lewis X analog on airway eosinophilia was examined in a guinea-pig model of asthma. Guinea-pigs were sensitized by repeated inhalation of ovalbumin. After a sing...

journal_title：International archives of allergy and immunology

authors： Sagara H,Ra C,Okada T,Shinohara S,Fukuda T,Okumura K,Makino S

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Patients with atopic dermatitis (AD) are frequently colonized with α-toxin-producing Staphylococcus aureus which is in turn positively correlated with the severity of eczema. METHODS:IN this study we addressed T cell proliferation and T cell as well as monocyte cytokine secretion upon α-toxin stimulation in...

journal_title：International archives of allergy and immunology

authors： Niebuhr M,Mamerow D,Heratizadeh A,Satzger I,Werfel T

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Airway closure is frequently observed in human asthma. However, limited information exists on the factors that cause this condition. In this study, an allergic cynomolgus monkey model was used to characterize the condition of airway closure and assess the contribution of histamine H1 receptors to this respon...

journal_title：International archives of allergy and immunology

authors： Skeans S,Lamca JE,House A,Celly CS,Hey JA,Chapman RW

更新日期：2005-05-01 00:00:00

abstract：:Aerosolized monoclonal antibodies (mAbs) specific for T-cell receptors (TCR) were used to manipulate T-cell function in airways of ovalbumin (OVA)-sensitized and -challenged mice with airway hyperresponsiveness (AHR). The inhaled mAbs were found to be effective at low doses, had little or no systemic effect and specif...

journal_title：International archives of allergy and immunology

authors： Lahn M,Kanehiro A,Hahn YS,Wands JM,Aydintug MK,O'Brien RL,Gelfand EW,Born WK

更新日期：2004-05-01 00:00:00

abstract：:Eosinophils are pleiotropic multi-functional leukocytes involved in initiation and propagation of diverse inflammatory responses. Recent studies examining eosinophil biology have focused on delineating the molecular basis of FIP1L1/PDGRFalpha-fusion gene induced HES, the molecular steps involved in eosinophil recruitm...

journal_title：International archives of allergy and immunology

authors： Hogan SP

更新日期：2007-01-01 00:00:00

abstract：:The morbidity and mortality of elderly onset asthma have recently been on the increase. To evaluate the allergic status of the elderly onset asthmatics, we performed skin tests for allergens and estimated serum total IgE levels of the patients. The proportion of the skin-test-positive patients among the elderly onset ...

journal_title：International archives of allergy and immunology

authors： Atsuta R,Akiyama K,Shirasawa T,Okumura K,Fukuchi Y,Ra C

更新日期：1999-01-01 00:00:00

abstract：:Delayed drug allergy reactions (DDAR) are potentially fatal. Certain human leukocyte antigen (HLA) alleles have been associated with delayed allergy reactions following the administration of particular drugs. Examples are HLA-B*57:01 (abacavir), HLA-B*15:02/HLA-A*31:01 (carbamazepine), and HLA-B*58:01 (allopurinol). B...

journal_title：International archives of allergy and immunology

authors： Sousa-Pinto B,Correia C,Gomes L,Gil-Mata S,Araújo L,Correia O,Delgado L

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Clustered severe adverse reactions to immunotherapy with olive pollen extracts have been occasionally reported in areas where olive trees are extensively grown. Allergic patients from these areas, in addition to the major olive pollen allergen Ole e 1, frequently recognize a recently described allergen, Ole ...

journal_title：International archives of allergy and immunology

authors： Duffort O,Palomares O,Lombardero M,Villalba M,Barber D,Rodríguez R,Polo F

更新日期：2006-01-01 00:00:00

abstract：:CD95 (APO-1) is a member of the TNF/nerve growth factor receptor superfamily, which is expressed on the surface of different types of cells. Cross-linking of CD95 leads to the induction of apoptosis. This may be of importance in many physiological systems, but seems to play a special role for the maintenance of immuno...

journal_title：International archives of allergy and immunology

authors： Lechner H,Amort M,Steger MM,Maczek C,Grubeck-Loebenstein B

更新日期：1996-07-01 00:00:00