Smoking attenuates increase in exhaled nitric oxide in atopic but not in nonatopic young adults with asthma.

abstract：BACKGROUND:Asthma is a major health problem worldwide, and the morbidity and mortality caused by asthma are on the rise. Corticosteroid therapies for asthma treatment frequently induce many side effects. Therefore, the development of new medicines that have both high efficacy and fewer side effects has been a scientifi...

journal_title：International archives of allergy and immunology

authors： Lim YJ,Na HS,Yun YS,Choi IS,Oh JS,Rhee JH,Cho BH,Lee HC

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Allergen molecule-based diagnosis has been suggested to facilitate the identification of disease-causing allergen sources and the prescription of allergen-specific immunotherapy (AIT). The aim of the current study was to compare allergen molecule-based IgE serology with allergen extract-based skin testing fo...

journal_title：International archives of allergy and immunology

authors： Saltabayeva U,Garib V,Morenko M,Rosenson R,Ispayeva Z,Gatauova M,Zulus L,Karaulov A,Gastager F,Valenta R

更新日期：2017-01-01 00:00:00

abstract：:Besides stem cell factor (SCF), additional fibroblast-derived mast cell growth factors have previously been described. Since keratinocytes have also been shown to produce SCF, we have studied the ability of culture supernatants from the human HaCaT keratinocyte cell line to induce SCF-independent mast cell differentia...

journal_title：International archives of allergy and immunology

authors： Welker P,Grabbe J,Czarnetzki BM

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Shellfish allergy is one of the major causes of life-threatening allergic reactions to food. The shrimp species Pandalus borealis is the commercially most important coldwater shrimp species, and its protein extract is commonly used in shrimp allergy diagnostics. However, the DNA sequence of its major allerge...

journal_title：International archives of allergy and immunology

authors： Myrset HR,Barletta B,Di Felice G,Egaas E,Dooper MM

更新日期：2013-01-01 00:00:00

abstract：:Phosphoinositide 3-kinases (PI3Ks) are known to be involved in a variety of cellular responses such as cell survival, proliferation, differentiation and cell migration. Recently, PI3Ks have been associated with the pathogenesis of asthma because various immune cells regulate allergic responses. Among the three classes...

journal_title：International archives of allergy and immunology

authors： Takeda M,Ito W,Tanabe M,Ueki S,Kihara J,Kato H,Tanigai T,Kayaba H,Sasaki T,Chihara J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DC) play a decisive role in the induction of allergen-induced Th1 and Th2 responses. Since the induction of allergen-specific Th1 responses has shown to inhibit allergen-induced Th2-type inflammation, in this study we investigated whether manipulated myeloid-derived DC pulsed with the specif...

journal_title：International archives of allergy and immunology

authors： Trujillo-Vargas CM,Ramirez-Pineda JR,Palmetshofer A,Grunewald S,Moll H,Berberich C,Erb KJ

更新日期：2005-07-01 00:00:00

abstract：RATIONALE:Evidence-based medicine represents the effort to highlight the best intervention for patients, clinicians, and policy makers, each from their respective viewpoint, to solve a particular health condition. According to a recently diffused grading system of evidence and recommendations for medical interventions,...

journal_title：International archives of allergy and immunology

authors： Compalati E,Baena-Cagnani R,Penagos M,Badellino H,Braido F,Gómez RM,Canonica GW,Baena-Cagnani CE

更新日期：2011-01-01 00:00:00

abstract：:Antibodies to specific autoantigens are serological hallmarks of systemic autoimmune diseases. These autoantibodies are thought to represent a consequence of immune dysregulation in these conditions, and, in part, have been shown to be involved in their pathologic consequences. However, the mechanisms that lead to the...

journal_title：International archives of allergy and immunology

authors： Hansen A,Dörner T,Lipsky PE

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Loss-of-function mutations of the filaggrin (FLG) gene cause an impaired skin barrier and increase the risk of atopic dermatitis. Interestingly, FLG mutations have also been found to be associated with a high risk of peanut allergy. OBJECTIVE:We investigated the association of FLG mutations with self-report...

journal_title：International archives of allergy and immunology

authors： Linneberg A,Fenger RV,Husemoen LL,Thuesen BH,Skaaby T,Gonzalez-Quintela A,Vidal C,Carlsen BC,Johansen JD,Menné T,Stender S,Melgaard M,Szecsi PB,Berg ND,Thyssen JP

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Modulating early immune response by application of bacteria and their by-products has been suggested as a preventive strategy against the development of allergic diseases. In light of this, the aim of the study was to test the effects of oral administration of bacterial lysates (BL) in a rat model of food al...

journal_title：International archives of allergy and immunology

authors： Ahrens B,Quarcoo D,Buhner S,Matricardi PM,Hamelmann E

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:L-selectin (CD62L) and Mac-1 (CD11b/CD18) play a crucial role in the infiltration of eosinophils. However, changes in CD62L and CD11b expression on eosinophils after stimulation with cytokines were little studied. METHODS:Eosinophils in peripheral blood of healthy volunteers were purified and cultured with ...

journal_title：International archives of allergy and immunology

authors： Momose T,Okubo Y,Horie S,Takashi S,Tsukadaira A,Suzuki J,Isobe M,Sekiguchi M

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The widespread house ant, Monomorium pharaonis (pharaoh ant, PA), was recently identified as a potential cause of respiratory allergies. However, there are no reports of the distribution of PA allergens in various environments. We developed specific ELISA inhibition assays and measured the distribution and a...

journal_title：International archives of allergy and immunology

authors： Kim CW,Song JS,Choi SY,Park JW,Hong CS

更新日期：2007-01-01 00:00:00

abstract：:HIV-1 RNA has become the standard for monitoring antiretroviral therapies. Dogma predicts, however, that a viral protein like p24 should be at least as good a marker of HIV disease activity, provided that it is measured with sufficient sensitivity and accuracy. Simple modifications including use of a more efficient vi...

journal_title：International archives of allergy and immunology

authors： Schüpbach J

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Allergic bronchopulmonary aspergillosis (ABPA) develops in the presence of predisposing conditions such as asthma and cystic fibrosis. Even ABPA accompanied by asthma is often complicated by chronic Pseudomonas aeruginosa or nontuberculous mycobacterial infection of the lower respiratory tract, rendering tre...

journal_title：International archives of allergy and immunology

authors： Tomomatsu K,Oguma T,Baba T,Toyoshima M,Komase Y,Taniguchi M,Asano K,Japan ABPM Research Program.

更新日期：2020-01-01 00:00:00

abstract：:The modulatory role of hormones in the regulation of the immune response has been well documented. Here, we present some thoughts on how sex hormones affect immunity, particularly at mucosal sites. We further discuss the possible pitfalls and difficulties associated with analysis of the data. ...

journal_title：International archives of allergy and immunology

authors： Stanisz AM,Kataeva G,Bienenstock J

更新日期：1994-01-01 00:00:00

abstract：:Monoclonal antibody 2F5 recognizing the ELDKWA epitope on HIV-1 gp41 has a significant neutralization potency against 90% of the investigated viruses of African, Asian, American, and European strains, but the antibody responses to the epitope 2F5 in HIV-1-infected individuals were very low. We attempted to induce high...

journal_title：International archives of allergy and immunology

authors： Xiao Y,Dong X,Chen Y

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Mugwort (Artemisia vulgaris) represents an important source of weed pollen allergens. The objectives of the present study were (i) to analyze the IgE binding profiles in a group of mugwort-allergic patients, (ii) to identify individual marker allergens crucial for the diagnosis of mugwort allergy and (iii) t...

journal_title：International archives of allergy and immunology

authors： Oberhuber C,Ma Y,Wopfner N,Gadermaier G,Dedic A,Niggemann B,Maderegger B,Gruber P,Ferreira F,Scheiner O,Hoffmann-Sommergruber K

更新日期：2008-01-01 00:00:00

abstract：:Cross-linking of FcepsilonRI on mast cells elicits positive signal transduction cascades that lead to the release of a variety of proinflammatory mediators. Mouse mast cells also express gp49B1 on their surface, an immunoglobulin superfamily member that bears two immunoreceptor tyrosine-based inhibitory motifs in its ...

journal_title：International archives of allergy and immunology

authors： Katz HR

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Patients with allergic rhinoconjunctivitis are susceptible to both nasal and ocular symptoms. The conjunctival provocation test (CPT) is an established diagnostic procedure used in allergic rhinoconjunctivitis, particularly to document a patient's current reactivity to allergens. To date, there are no intern...

journal_title：International archives of allergy and immunology

authors： Dogan S,Astvatsatourov A,Deserno TM,Bock F,Shah-Hosseini K,Michels A,Mösges R

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Th2 cell infiltration is a characteristic feature of allergic chronic sinusitis. However, the mechanisms that cause the predominance of Th2 cells in this disease have yet to be clarified. The airway is often exposed to not only Th2 cytokines but also bacterial products such as lipopolysaccharides (LPS). A CC...

journal_title：International archives of allergy and immunology

authors： Fukumoto A,Nonaka M,Ogihara N,Pawankar R

更新日期：2008-01-01 00:00:00

abstract：:In this study, we postulated that repeated cycles of IgE passive sensitisation and antigen challenge may play a role in up-regulating eosinophil response in allergic conditions. Antigen-mediated stimulation of the pleural cavity of rats passively sensitised with a single injection of IgE anti-DNP resulted in mast cell...

journal_title：International archives of allergy and immunology

authors： Calheiros AS,Aguiar Pires AL,Pereira da Silva J,Cordeiro RS,Martins MA,Lima MC

更新日期：2001-12-01 00:00:00

abstract：:Sera of 54 symptomatic workers showing sensitization to isocyanate-human serum albumin (HSA) conjugates were subjected to parallel enzyme allergosorbent test (EAST) and CAP measurements to determine IgE antibodies to diphenyl-methane diisocyanate-HSA, toluene diisocyanate-HSA and hexamethylene diisocyanate-HSA. Result...

journal_title：International archives of allergy and immunology

authors： Baur X,Chen Z,Flagge A,Posch A,Raulf-Heimsoth M

更新日期：1996-08-01 00:00:00

abstract：:There is a great need to develop a method for making an accurate and reliable in vitro diagnosis of adverse hypersensitivity reactions to drugs. We measured the amount of sulfidoleukotriene (sLT) released from the peripheral blood leukocytes obtained from 25 patients who developed hypersensitivity reactions following ...

journal_title：International archives of allergy and immunology

authors： Kubota Y,Imayama S,Toshitani A,Miyahara H,Tanahashi T,Uemura Y,Koga T,Sugawara N,Kurimoto F,Hata K

更新日期：1997-12-01 00:00:00

abstract：:The last decade has seen the rapid development of research investigating the mechanisms of apoptosis in a variety of experimental systems. Among the multitude of changes observed in apoptotic cells, chromatin cleavage is considered a biochemical hallmark of apoptosis. Chromatin fragmentation is an enzymatic process wh...

journal_title：International archives of allergy and immunology

authors： Zhivotovsky B,Wade D,Nicotera P,Orrenius S

更新日期：1994-12-01 00:00:00

abstract：:Based on in vitro findings with mouse mast cells and in vivo findings in mice, we report that dexamethasone or cyclosporin A can have at least three actions which interfere with the pathogenesis IgE-, mast-cell-, and cytokine-dependent inflammatory reactions: suppression of the IgE-dependent increase in tumor necrosis...

journal_title：International archives of allergy and immunology

authors： Wershil BK,Furuta GT,Lavigne JA,Choudhury AR,Wang ZS,Galli SJ

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Diagnosis and immunotherapy of house-dust mite (HDM) allergy is still based on natural allergen extracts. The aim of this study was to analyze commercially available Dermatophagoides pteronyssinus extracts from different manufacturers regarding allergen composition and content and whether variations may affe...

journal_title：International archives of allergy and immunology

authors： Casset A,Mari A,Purohit A,Resch Y,Weghofer M,Ferrara R,Thomas WR,Alessandri C,Chen KW,de Blay F,Valenta R,Vrtala S

更新日期：2012-01-01 00:00:00

abstract：:Ever since the realization that T lymphocytes are key players in the defense against pathogens and tumors, a major aim of immunologists has been to understand the relationship between the functional and migratory properties of antigen-specific T cells. The current paradigm proposes that T cells follow organ-specific t...

journal_title：International archives of allergy and immunology

authors： Iparraguirre A,Weninger W

更新日期：2003-12-01 00:00:00

abstract：:Mast cells are recognized not only as the major effector cells of type I hypersensitivity reactions but also as an important player of innate immune response against bacterial infection. Type I IFNs are also involved in the response against bacterial infection. However, the role of type I IFNs and their associated Jan...

journal_title：International archives of allergy and immunology

authors： Mori Y,Hirose K,Suzuki K,Nakajima H,Seto Y,Ikeda K,Shimoda K,Nakayama K,Saito Y,Iwamoto I

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Cross-sectional epidemiological studies have demonstrated that farm milk from traditional farm settings possesses allergoprotective properties. Up to now, it has not been clarified which milk ingredient is responsible for protection against allergic diseases. As farm milk is rich in conjugated linoleic acids...

journal_title：International archives of allergy and immunology

authors： Böcking C,Harb H,Ege MJ,Zehethofer N,Fischer K,Krauß J,Holst O,Nüsing RM,Lindner B,von Mutius E,Renz H,Garn H,Pfefferle PI

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Nonsteroidal anti-inflammatory drugs (NSAIDS) are among the most common causes of drug hypersensitivity (HS) reactions. The diagnosis is based on a careful clinical history, and provocation tests are considered the gold standard for diagnosis. Skin tests have some value to study reactions to pyrazolones. Lab...

journal_title：International archives of allergy and immunology

authors： Rebelo Gomes E,Geraldes L,Gaspar Â,Malheiro D,Cadinha S,Abreu C,Chambel M,Almeida E,Faria E,Portuguese Society of Allergology and Clinical Immunology (SPAIC) Drug Allergy Interest Group.

更新日期：2016-01-01 00:00:00