Impact of Allergy and Eosinophils on the Morbidity of Chronic Rhinosinusitis with Nasal Polyps in Northwest China.

abstract：BACKGROUND:A subset of drug-intolerant patients show a marked propensity to react to several chemically unrelated antibacterial drugs. This condition is termed multiple drug allergy syndrome (MDAS). The pathogenesis of MDAS is still unclear. A possible mechanism is that a nonspecific patient-related factor leading to d...

journal_title：International archives of allergy and immunology

authors： Asero R,Tedeschi A,Lorini M,Caldironi G,Barocci F

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Patients with atopic dermatitis (AD) are frequently colonized with α-toxin-producing Staphylococcus aureus which is in turn positively correlated with the severity of eczema. METHODS:IN this study we addressed T cell proliferation and T cell as well as monocyte cytokine secretion upon α-toxin stimulation in...

journal_title：International archives of allergy and immunology

authors： Niebuhr M,Mamerow D,Heratizadeh A,Satzger I,Werfel T

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:We previously showed that immunization of mice with plasmid DNA (pDNA) encoding the Escherichia coli beta-galactosidase gene (pCMV-LacZ) induces a Th1 response, whereas beta-galactosidase (beta-gal) in saline or alum induces a Th2 response. Furthermore, the Th1 response dominates over the Th2 response and do...

journal_title：International archives of allergy and immunology

authors： Lee DJ,Tighe H,Corr M,Roman M,Carson DA,Spiegelberg HL,Raz E

更新日期：1997-05-01 00:00:00

abstract：:Recent studies have demonstrated that pulmonary surfactant protein (SP)-A plays a potential role in modifying inflammation and immune function. To see whether SP-A could modify IL-8 production and release by eosinophils stimulated with ionomycin, SP-A purified from surfactant recovered from patients with alveolar prot...

journal_title：International archives of allergy and immunology

authors： Cheng G,Ueda T,Nakajima H,Nakajima A,Kinjyo S,Motojima S,Fukuda T

更新日期：1998-09-01 00:00:00

abstract：:Antibody response after immunization with surface-coupled ovalbumin (OVA) of liposomes was investigated in mice. OVA was coupled to the surface of liposome via amino groups using glutaraldehyde. OVA-liposome conjugate induced a significant anti-OVA IgG antibody production in mice. However, no IgE antibody production s...

journal_title：International archives of allergy and immunology

authors： Naito S,Horino A,Nakayama M,Nakano Y,Nagai T,Mizuguchi J,Komuro K,Uchida T

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:The presence of autoantibodies reacting with the high affinity IgE receptor (FcepsilonRIalpha) usually indicates a more severe form of chronic urticaria (CU). Previously, we showed an increased lymphocyte reactivity in CU patients; however, the relation between enhanced cellular immunity and the presence of ...

journal_title：International archives of allergy and immunology

authors： Hidvégi B,Nagy E,Szabó T,Temesvári E,Marschalkó M,Kárpáti S,Horváth A,Gergely P

更新日期：2003-10-01 00:00:00

abstract：:A case of anaphylaxis following a bite from a Siberian hamster (SH; Phodopus sungorus) is described. Skin prick tests with hair, urine and salivary gland extracts from SH were positive, while the tests were negative for hair extracts from other rodents. IgE immunoblotting with the patient serum revealed 3 IgE-binding ...

journal_title：International archives of allergy and immunology

authors： Torres JA,Pastor-Vargas C,de las Heras M,Vivanco F,Cuesta J,Sastre J

更新日期：2012-01-01 00:00:00

abstract：:Fourteen Brown-Norway rats were pretreated with physiological saline (n = 7) or 500 micrograms Sephadex (n = 7) intratracheally. 24 h later, a bronchial provocation test was performed under pentobarbital anaesthesia using increasing doses of acetylcholine aerosol and the degree of bronchospasm was measured using a mod...

journal_title：International archives of allergy and immunology

authors： Kubin R,Deschl U,Linssen M,Wilhelms OH

更新日期：1992-01-01 00:00:00

abstract：:Guinea pigs were sensitized with 2,4-toluene diisocyanate (TDI) by a repetitive application onto the bilateral nasal vestibules once a day for 5 consecutive days. When these animals were further treated with TDI for additional 9 weeks, a number of these animals exhibited external symptoms similar to those in human ast...

journal_title：International archives of allergy and immunology

authors： Sugawara Y,Okamoto Y,Sawahata T,Tanaka K

更新日期：1993-01-01 00:00:00

abstract：:We examined the capacity of interleukin-4 (IL) production from lymphocytes and basophils, isolated from the peripheral blood of allergic patients sensitive to house dust mite, after stimulation with mite extract. IL-4 production was measured by a sensitive bioassay based on coculture with CT.h4S (a human IL-4-responsi...

journal_title：International archives of allergy and immunology

authors： Ochi H,Tanaka T,Katada Y,Naka T,Aitani M,Hashimoto S,Maeda K,Toyoshima K,Igarashi T,Suemura M,Kishimoto T

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:It is not known why some foods sensitizing via the gastrointestinal tract are prevalent allergenic foods and others are not. Eating habits, processing, and the food matrix have been suggested to influence the allergenicity of a given food. Factors related to protein structure, such as stability to digestion,...

journal_title：International archives of allergy and immunology

authors： Kroghsbo S,Bøgh KL,Rigby NM,Mills EN,Rogers A,Madsen CB

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:In a subgroup of patients with atopic eczema (AE), aeroallergens are relevant eliciting factors. The atopy patch test (APT) was proposed as inflammation model for AE. OBJECTIVE:It was the aim of this study to investigate the effect of pretreatment with 1% pimecrolimus cream (Elidel) on the APT and skin pric...

journal_title：International archives of allergy and immunology

authors： Weissenbacher S,Traidl-Hoffmann C,Eyerich K,Katzer K,Braeutigam M,Loeffler H,Hofmann H,Behrendt H,Ring J,Darsow U

更新日期：2006-01-01 00:00:00

abstract：UNLABELLED:T-bet is crucially implicated in Th1 differentiation due to its strong promoting activity for IFN-gamma gene transcription. However, the regulatory role of T-bet in Th2 cytokines is not fully delineated. METHODS:The effect of T-bet on mRNA expression as well as the promoter activity of IL-4 in human T cells...

journal_title：International archives of allergy and immunology

authors： Kitamura N,Kitamura F,Kaminuma O,Miyatake S,Tatsumi H,Nemoto S,Mori A

更新日期：2007-01-01 00:00:00

abstract：:A 73-year-old man developed organized pneumonia with severe right-sided eosinophilic pleural effusion (PE). CD69+ and HLA-DR+ eosinophils in PE were 90 and 31%, respectively, but were undetectable in peripheral blood (PB). CD4+, CD45RA+ (naive) and CD4+, CD45RO+ (memory) cells in PB, PE and bronchoalveolar lavage (BAL...

journal_title：International archives of allergy and immunology

authors： Hossain M,Okubo Y,Yamaguchi S,Horie S,Itoh S,Sugii S,Takatsu K,Oguchi T,Sekiguchi M

更新日期：1996-10-01 00:00:00

abstract：:Increased serum IgE and enhanced susceptibility to viral infections, decreased levels of interferons, lymphocytic skin infiltrates and IgE-bearing epidermal Langerhans cells are striking features in patients with atopic eczema (AE). Since the hyper-IgE syndrome is known to improve under alpha-interferon (alpha-IFN) th...

journal_title：International archives of allergy and immunology

authors： Gruschwitz MS,Peters KP,Heese A,Stosiek N,Koch HU,Hornstein OP

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Wheat is known as the most widely consumed food all over the world. Although many types of wheat allergy have been recognized, their treatment still has a long way to go due to the complex pathogenesis. Oral immunotherapy (OIT) is under investigation for the treatment of wheat allergies. Previous studies hav...

journal_title：International archives of allergy and immunology

authors： Li X,Miyakawa T,Takano T,Nakajima-Adachi H,Tanokura M,Hachimura S

更新日期：2020-01-01 00:00:00

abstract：:Immunological suppression is one of the important aspects which govern the regulation of the immune response. Clonal deletion, clonal anergy and the activity of suppressor cells were proposed as mechanisms leading to this phenomenon. In this review we provide evidence for the existence of suppressor (Ts) cells and the...

journal_title：International archives of allergy and immunology

authors： Arnon R,Teitelbaum D

更新日期：1993-01-01 00:00:00

abstract：:Based on in vitro findings with mouse mast cells and in vivo findings in mice, we report that dexamethasone or cyclosporin A can have at least three actions which interfere with the pathogenesis IgE-, mast-cell-, and cytokine-dependent inflammatory reactions: suppression of the IgE-dependent increase in tumor necrosis...

journal_title：International archives of allergy and immunology

authors： Wershil BK,Furuta GT,Lavigne JA,Choudhury AR,Wang ZS,Galli SJ

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) is an acute, systemic vasculitis in children, with an etiology that is not completely understood. It is assumed that the development of KD is mediated by an immunologic response. Several reports from East Asia have found a higher prevalence of atopic diseases among patients with KD, but...

journal_title：International archives of allergy and immunology

authors： Hassidim A,Merdler I,Chorin O,Merdler-Rabinowicz R,Dallal I,Perlman M,Chorin E

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Subcutaneous immunotherapy for respiratory allergy has shown a long lasting efficacy after its discontinuation, whereas evidence in the case of sublingual immunotherapy (SLIT) is weak. This retrospective study evaluates whether SLIT exerts a long-lasting effect and whether it relates to its duration. METHOD...

journal_title：International archives of allergy and immunology

authors： Marogna M,Bruno M,Massolo A,Falagiani P

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Omalizumab, an anti-immunoglobulin E (IgE) monoclonal antibody, inhibits the binding of circulating IgE to mast cells and basophils, resulting in fewer episodes of airway inflammation, asthma symptoms and exacerbations in patients with severe allergic asthma. Treatment of patients with asthma using omalizuma...

journal_title：International archives of allergy and immunology

authors： Mizuma H,Tanaka A,Uchida Y,Fujiwara A,Manabe R,Furukawa H,Kuwahara N,Fukuda Y,Kimura T,Jinno M,Ohta S,Yamamoto M,Matsukura S,Adachi M,Sagara H

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Sweating can worsen atopic dermatitis (AD). The purpose of this work was to study the associations between reactivity to autologous sweat and the clinical severity of AD as well as investigate the possible wheal-inducing factors of sweat. METHODS:Intracutaneous skin tests with autologous sweat were performe...

journal_title：International archives of allergy and immunology

authors： Ilves T,Virolainen A,Harvima IT

更新日期：2016-01-01 00:00:00

abstract：:Monocytes and lymphocytes from human blood contain 0.043 +/- 0.007 and 0.053 +/- 0.014 pg histamine/cell, respectively, which can be released by a number of stimulants (A 23187, C5a, substance P, specific allergen). The release process takes 60-120 min to reach its end point, in contrast to tissue mast cells which com...

journal_title：International archives of allergy and immunology

authors： Schmutzler W,Bolsmann K,Zwadlo-Klarwasser G

更新日期：1995-05-01 00:00:00

abstract：RATIONALE:Evidence-based medicine represents the effort to highlight the best intervention for patients, clinicians, and policy makers, each from their respective viewpoint, to solve a particular health condition. According to a recently diffused grading system of evidence and recommendations for medical interventions,...

journal_title：International archives of allergy and immunology

authors： Compalati E,Baena-Cagnani R,Penagos M,Badellino H,Braido F,Gómez RM,Canonica GW,Baena-Cagnani CE

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The allergenic potential of chicken egg white ovomucoid (OVM) is thought to depend on its stability to heat treatment and digestion. Pepsin-digested fragments have been speculated to continue to exert an allergenic potential. OVM was digested in simulated gastric fluid (SGF) to examine the reactivity of the ...

journal_title：International archives of allergy and immunology

authors： Takagi K,Teshima R,Okunuki H,Itoh S,Kawasaki N,Kawanishi T,Hayakawa T,Kohno Y,Urisu A,Sawada J

更新日期：2005-01-01 00:00:00

abstract：:We describe an HLA-B8, DR3-positive patient with localized morphea after silicone gel breast implantation for cosmetic reasons. We believe that this case suggests that a genetic background, i.e. HLA-B8, DR3 haplotype, is involved in the autoimmune response to silicone. ...

journal_title：International archives of allergy and immunology

authors： Di Lorenzo G,Mansueto P,Melluso M,Sangiorgi GB,Cigna D,Candore G,Caruso C

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The Notch signaling pathway plays an important role in regulating human immune function, but the relationship between allergic rhinitis (AR) and Notch signaling remains unclear. OBJECTIVE:To investigate the role of Notch signaling in the pathogenesis of AR and its regulation on Foxp3-Treg cells. METHOD:The...

journal_title：International archives of allergy and immunology

authors： Jiao WE,Wei JF,Kong YG,Xu Y,Tao ZZ,Chen SM

更新日期：2019-01-01 00:00:00

abstract：:Antibodies to specific autoantigens are serological hallmarks of systemic autoimmune diseases. These autoantibodies are thought to represent a consequence of immune dysregulation in these conditions, and, in part, have been shown to be involved in their pathologic consequences. However, the mechanisms that lead to the...

journal_title：International archives of allergy and immunology

authors： Hansen A,Dörner T,Lipsky PE

更新日期：2000-09-01 00:00:00

abstract：:Transforming growth factor-beta 1 (TGF-beta(1)) is a key regulator of immune tolerance. TGF-beta(1) controls T lymphocyte activation and is involved in the immunosuppressive function and generation of regulatory T lymphocytes. Connective tissue growth factor (CTGF) has an essential role in the formation of connective ...

journal_title：International archives of allergy and immunology

authors： Kunzmann S,Seher A,Kramer BW,Schenk R,Schütze N,Jakob F,Sebald W,Speer CP

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Pseudomonas aeruginosa phospholipase C (PLC) is a critical component in the pathogenesis of severe P. aeruginosa infections. However, P. aeruginosa can produce a hemolytic (PLC-H) as well as a nonhemolytic (PLC-N) variant, both having a MW of about 77 kD. In the past, studies did not distinguish between both...

journal_title：International archives of allergy and immunology

authors： König B,Vasil ML,König W

更新日期：1997-02-01 00:00:00