Immediate-Type Hypersensitivity Cross-Reactions to Proton Pump Inhibitors: A Descriptive Study of Data from the French National Pharmacovigilance Database.

abstract：INTRODUCTION:Venom immunotherapy (VIT) is considered to be the gold-standard treatment for patients with Hymenoptera venom allergy. Data regarding VIT in bee venom (BV) allergic patients are scarce. AIM:The aim of this study was to evaluate the outcome of VIT in patients with exclusive BV allergy and to try to define ...

journal_title：International archives of allergy and immunology

authors： Rosman Y,Nashef F,Cohen-Engler A,Meir-Shafrir K,Lachover-Roth I,Confino-Cohen R

更新日期：2019-01-01 00:00:00

abstract：:CD40 is a surface antigen expressed on B cells. The CD40 ligand (CD40L) is expressed on activated T cells. Interaction between CD40 and CD40L is critical for proliferation and isotype switching in the context of a response to a T-cell-dependent antigen. Patients with X-linked hyper-IgM syndrome (HIGMX-1) in their CD40...

journal_title：International archives of allergy and immunology

authors： Castigli E,Fuleihan R,Ramesh N,Tsitsikov E,Tsytsykova A,Geha RS

更新日期：1995-05-01 00:00:00

abstract：:We studied the binding activities of IgE, IgG and IgA antibodies in patients with allergy to hen's egg white against two different ovalbumin (OVA) preparations, which were physically or chemically denatured OVA and enzyme-digested OVA fragments. The binding activities of IgE antibodies to these OVA preparations with t...

journal_title：International archives of allergy and immunology

authors： Honma K,Kohno Y,Saito K,Shimojo N,Tsunoo H,Niimi H

更新日期：1994-01-01 00:00:00

abstract：:Fibroblast-derived growth factors like SCF are able to upregulate the expression of mast cell characteristics in human multilineage hematopoietic progenitor cells. Other factors, like GM-CSF, have been reported to inhibit this process, probably by the competitive recruitment of cells not belonging to the mast cell lin...

journal_title：International archives of allergy and immunology

authors： Welker P,Grabbe J,Zuberbier T,Henz BM

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:The coexistence of asthma and allergic rhinitis (AR) and its distinct association with obesity have been reported. However, few studies have differentiated the two types of AR, i.e., perennial (PAR) and seasonal AR (SAR), with regard to their associations with asthma and obesity. The aim of this study was to...

journal_title：International archives of allergy and immunology

authors： Matsumoto M,Konno S,Kimura H,Takei N,Kimura H,Shimizu K,Goudarzi H,Suzuki M,Hashino S,Nishimura M

更新日期：2018-01-01 00:00:00

abstract：:We have systematically investigated the capacity of highly purified human peripheral CD8+ T cells to produce interleukin (IL)-4 and interferon (IFN)-gamma when triggered by different stimuli. CD8+ T cells were isolated from peripheral blood by positive selection to > 99% purity and stimulated with one of three differe...

journal_title：International archives of allergy and immunology

authors： Li Y,Richards D,Noble A,Kemeny DM

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Serum-derived hyaluronan (HA)-associated proteins (SHAPs), the heavy chains of inter-α-trypsin inhibitor, covalently bind to HA to form the SHAP-HA complex. The SHAP-HA complex is involved in the pathophysiology of inflammatory diseases, including rheumatoid arthritis. We investigated whether this complex is...

journal_title：International archives of allergy and immunology

authors： Zhu L,Zhuo L,Kimata K,Yamaguchi E,Watanabe H,Aronica MA,Hascall VC,Baba K

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Assessing high-sensitivity C-reactive protein (hs-CRP) in relation to allergic endpoints can shed light on both the mechanisms of allergic disease development and early non-communicable disease prevention. However, only a few epidemiological studies so far have investigated the relationship in children and a...

journal_title：International archives of allergy and immunology

authors： Yang BY,Markevych I,Harris C,Standl M,Schikowski T,Koletzko S,Herberth G,Bauer CP,von Berg A,Berdel D,Dong GH,Heinrich J

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:In naive rodents, repeated exposure to aerosolized antigen induces suppression of the Th2 response to the antigen. We hypothesized that more prolonged exposure of established asthma model to antigen aerosols may downregulate asthmatic phenotype. METHODS:After establishing an ovalbumin (OVA)-induced asthma m...

journal_title：International archives of allergy and immunology

authors： Sakai K,Yokoyama A,Kohno N,Hamada H,Hiwada K

更新日期：2001-10-01 00:00:00

abstract：AIM:To investigate the potential risk factors in patients who have experienced anaphylaxis from drugs. METHOD:The study included 281 adult patients (median age 40 years; 76.5% female) who experienced immediate types of hypersensitivity reaction to a drug. The patients were divided into an anaphylaxis group and a nonan...

journal_title：International archives of allergy and immunology

authors： Demir S,Erdenen F,Gelincik A,Unal D,Olgac M,Coskun R,Colakoglu B,Buyukozturk S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Natural rubber latex proteins have been implicated in severe allergy in individuals exposed to latex products, particularly health care workers. Until recently, only crude antigens were available to study the immune response in these patients. In recent years a number of relevant allergens have been purified...

journal_title：International archives of allergy and immunology

authors： Johnson BD,Kurup VP,Sussman GL,Arif SA,Kelly KJ,Beezhold DH,Fink JN

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Autoimmune disorders are considered to be associated with a Th1 immune response while allergic diseases with a Th2 response. We carried out a study to determine whether there is an inverse relationship between allergic diseases in IgE-sensitized children or positive skin-prick test reactions to allergens and...

journal_title：International archives of allergy and immunology

authors： Caffarelli C,Cavagni G,Pierdomenico R,Chiari G,Spattini A,Vanelli M

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:The fractional concentration of exhaled nitric oxide (FeNO) is a surrogate biomarker for Th2-dependent bronchial inflammation. The present study investigated whether FeNO may characterize allergic rhinitis (AR) patients. METHODS:A total of 553 AR patients (497 males, mean age 28.8 years) were evaluated. Tho...

journal_title：International archives of allergy and immunology

authors： Ciprandi G,Gallo F,Ricciardolo FL,Cirillo I

更新日期：2017-01-01 00:00:00

abstract：:Thymulin is a nonapeptide hormone isolated from the thymus gland. It has immunomodulatory effects which have not yet been well defined. Its major actions have been shown to be on T-cells and their immature precursors. In this study, thymulin was tested in vitro for its effect on the release of IL-1 alpha, IL-2, IL-6 a...

journal_title：International archives of allergy and immunology

authors： Safieh-Garabedian B,Ahmed K,Khamashta MA,Taub NA,Hughes GR

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Recently, the relationship between antigen contact via skin (skin sensitization) and the development of food allergies has gained increasing attention. However, few studies have examined the effects of skin sensitization on healthy skin. OBJECTIVE:To examine the effect of sensitization in healthy skin on Ig...

journal_title：International archives of allergy and immunology

authors： Koshiba R,Oba T,Fuwa A,Arai K,Sasaki N,Kitazawa G,Hattori M,Matsuda H,Yoshida T

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:Cry j 1 and Cry j 2 are thought to be the major allergens of Japanese cedar pollen. HLA class II types capable of presenting T-cell epitopes in both allergens and their role in induction of T-cell subsets are not well known. METHODS:CD4+ T (Th)-cell clones (TCCs) specific to either Cry j 1 or Cry j 2 were g...

journal_title：International archives of allergy and immunology

authors： Sone T,Morikubo K,Shimizu K,Komiyama N,Tsunoo H,Kino K

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Pre-clinical and clinical studies have evaluated the efficacy of probiotics in allergy. However, predictive in vitro systems for rational strain selection are still missing. METHODS:We developed a novel in vitro screening system for the characterization of probiotics with anti-allergic potential. In this mo...

journal_title：International archives of allergy and immunology

authors： Holvoet S,Zuercher AW,Julien-Javaux F,Perrot M,Mercenier A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Omalizumab, an anti-immunoglobulin E (IgE) monoclonal antibody, inhibits the binding of circulating IgE to mast cells and basophils, resulting in fewer episodes of airway inflammation, asthma symptoms and exacerbations in patients with severe allergic asthma. Treatment of patients with asthma using omalizuma...

journal_title：International archives of allergy and immunology

authors： Mizuma H,Tanaka A,Uchida Y,Fujiwara A,Manabe R,Furukawa H,Kuwahara N,Fukuda Y,Kimura T,Jinno M,Ohta S,Yamamoto M,Matsukura S,Adachi M,Sagara H

更新日期：2015-01-01 00:00:00

abstract：:IL-13 is a relatively novel cytokine produced by activated T cells. IL-13 inhibits the production of proinflammatory cytokines and chemokines by activated monocytes, induces B cell proliferation and differentiation, including IgE production, and the expression of certain adhesion molecules on endothelial cells. All th...

journal_title：International archives of allergy and immunology

authors： de Vries JE,Zurawski G

更新日期：1995-03-01 00:00:00

abstract：:Recent studies have demonstrated that pulmonary surfactant protein (SP)-A plays a potential role in modifying inflammation and immune function. To see whether SP-A could modify IL-8 production and release by eosinophils stimulated with ionomycin, SP-A purified from surfactant recovered from patients with alveolar prot...

journal_title：International archives of allergy and immunology

authors： Cheng G,Ueda T,Nakajima H,Nakajima A,Kinjyo S,Motojima S,Fukuda T

更新日期：1998-09-01 00:00:00

abstract：:A significant increase in the incidence of allergy and asthma has been observed during the past decades. The background of this phenomenon has not been well explained, but changes in lifestyle and habits are heavily discussed as contributing factors. Among these is a too clean environment, which may predispose individ...

journal_title：International archives of allergy and immunology

authors： Zaknun D,Schroecksnadel S,Kurz K,Fuchs D

更新日期：2012-01-01 00:00:00

abstract：:We investigated the in vitro adhesion of 51Cr-labeled lymphocytes to cultured brain endothelial cells and the in vivo expression of intercellular adhesion molecule-1 (ICAM-1) on cerebral endothelial cells in a rat model of experimental allergic encephalomyelitis (EAE) before and after treatment with lipopolysaccharide...

journal_title：International archives of allergy and immunology

authors： Matsuda M,Tsukada N,Miyagi K,Yanagisawa N

更新日期：1995-04-01 00:00:00

abstract：:In contrast to mast cells and basophils, the high affinity IgE receptor (FcepsilonRI) on antigen-presenting cells (APC) shows structural and functional differences. It consists only of a minimal structure of one alpha- and two gamma-chains and enables APC to efficiently take up and present antigen in IgE-mediated dela...

journal_title：International archives of allergy and immunology

authors： Kraft S,Katoh N,Novak N,Koch S,Bieber T

更新日期：2001-01-01 00:00:00

abstract：:Adhesion molecules of microvascular endothelial cells play a key role in the inflammatory processes involved in nonallergic sinusitis. We investigated the cytokine-regulated expression of intercellular adhesion molecule-1 (ICAM-1), E-selectin and vascular cell adhesion molecule-1 (VCAM-1), and the effect of dexamethas...

journal_title：International archives of allergy and immunology

authors： Yamamoto Y,Ikeda K,Watanabe M,Shimomura A,Suzuki H,Oshima T,Imamura Y,Ohuchi K,Takasaka T

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Recombinant dog allergens, rCan f 1 and rCan f 2, and their antibodies are good tools for the characterization of dog allergens in order to develop modern therapeutic and preventive methods for dog allergy. METHODS:In this study, cDNA was synthesized from the mRNA of dog salivary glands and cloned into the ...

journal_title：International archives of allergy and immunology

authors： Kamata Y,Miyanomae A,Nakayama E,Miyanomae T,Tajima T,Hoshi H

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Penicillins and cephalosporins are the most frequent causes of hypersensitivity reactions (HRs) to drugs in children. Among cephalosporins for intravenous use, ceftriaxone (CT) is the most frequently prescribed in Italy. The aims of this study were to evaluate the diagnostic methods for CT hypersensitivity...

journal_title：International archives of allergy and immunology

authors： Mori F,Liccioli G,Piccorossi A,Sarti L,Barni S,Giovannini M,Azzari C,Manfredi M,Novembre E

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:We reported on the constitutive interferon-gamma receptor (IFN-gammaR) expression on eosinophils. But signal transduction through IFN-gammaR on eosinophils remains to be elucidated. In this study, we examined the involvement of the Jak/Stat pathway in the signaling of eosinophils after IFN-gammaR conjugation...

journal_title：International archives of allergy and immunology

authors： Ochiai K,Ishihara C,Tomioka H

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Numerous strategies have been proposed for the treatment of peanut allergies, but despite the steady advancement in our understanding of atopic immune responses and the increasing number of deaths each year from peanut anaphylaxis, there is still no safe, effective, specific therapy for the peanut-sensitive ...

journal_title：International archives of allergy and immunology

authors： Bannon GA,Cockrell G,Connaughton C,West CM,Helm R,Stanley JS,King N,Rabjohn P,Sampson HA,Burks AW

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:A negative association has been observed between infections and allergy in several studies. The aim of the present study was to examine whether tuberculosis and leprosy patients have more or fewer allergies than healthy individuals. METHOD:Sera from tuberculosis patients, leprosy patients and healthy contro...

journal_title：International archives of allergy and immunology

authors： Ellertsen LK,Wiker HG,Egeberg NT,Hetland G

更新日期：2005-11-01 00:00:00

abstract：:Eosinophils participate in the inflammatory response seen in allergy and helminthic infestation. Their release of granule-bound cationic proteins may play a role in these diseases. Therefore, we investigated mechanisms involved in the release of eosinophil cationic protein (ECP). Serum-opsonized zymosan was phagocytos...

journal_title：International archives of allergy and immunology

authors： Egesten A,Blom M,Calafat J,Janssen H,Knol EF

更新日期：1998-02-01 00:00:00