Abstract:
:The tendency of DNA to form fibers upon condensation with counterions is reviewed. It is shown that chromatin fibers may acquire a relatively constant diameter of about 30 nm simply as an optimal size achieved upon neutralization of DNA, without requiring a repetitive internal structure. Thus the size of chromatin fibers would not be determined by any specific spatial interaction between DNA and histones. The driving force for the formation of fibers in chromatin would be similar to that found in proteins when they acquire a compact globular shape.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Subirana JAdoi
10.1016/0014-5793(92)80416-ekeywords:
subject
Has Abstractpub_date
1992-05-11 00:00:00pages
105-7issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(92)80416-Ejournal_volume
302pub_type
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