Abstract:
:Antiparaoxon immune sera were employed in a new immunoassay based on competition between acetylcholinesterase and antibodies for the binding of paraoxon. Unlike radioimmunoassay, the new assay described herein can be extended to predict the feasibility of antibodies to confer in vivo protection of acetylcholinesterase against organophosphate poisoning. The toxicity of paraoxon was reduced in mice which were preinjected with the immune sera.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Heldman E,Balan A,Horowitz O,Ben-Zion S,Torten Mdoi
10.1016/0014-5793(85)81079-6subject
Has Abstractpub_date
1985-01-28 00:00:00pages
243-8issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(85)81079-6journal_volume
180pub_type
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