Abstract:
:Complete [1H]NMR resonance assignments are presented for the second of the three zinc fingers from SW15 as it appears in both 1- and 2-finger constructs. Signals from finger 2 are unaffected by the presence or absence of finger 1, showing that the protein has a modular construction. The structure of finger 2 comprises a helix running from N56 to Q67, and a region approximating to an anti-parallel beta-sheet running from Y42 to F53. These features combine to produce a hydrophobic core in the structure involving the invariant residues Y42, F53, L59 and H62.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Neuhaus D,Nakaseko Y,Nagai K,Klug Adoi
10.1016/0014-5793(90)80184-ksubject
Has Abstractpub_date
1990-03-26 00:00:00pages
179-84issue
2eissn
0014-5793issn
1873-3468journal_volume
262pub_type
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