Estrogenic activity of a polyphenolic extract of the leaves of Epimedium brevicornum.

abstract：:A new diterpenoid ester, fritillahupehin (1) together with three known fatty acids: palmitic acid (2), lignoceric acid (3) and azelaic acid (4) were isolated from the bulbs of Fritillaria hupehensis Hsiao and K.C. Hsia. The structure of fritillahupehin has been established to be ent-kauran-16beta-yl lignocerate by mea...

journal_title：Fitoterapia

authors： Ruan H,Zhang Y,Wu J,Deng S,Sun H,Fujita T

更新日期：2002-07-01 00:00:00

abstract：:The antioxidant effect of aqueous methanolic herb extracts of Serratula coronata, S. wolffii and S. tinctoria was investigated using both enzyme-dependent and enzyme-independent systems. The extracts displayed concentration-dependent inhibition of lipid peroxidation. Flavonoids and ecdysteroids present in the extracts...

journal_title：Fitoterapia

authors： Báthori M,Zupkó I,Hunyadi A,Gácsné-Baitz E,Dinya Z,Forgó P

更新日期：2004-03-01 00:00:00

abstract：:Six new shionane-type triterpenes, astershionones A-F (1-6), were obtained from the roots and rhizomes of Aster tataricus. Their structures were elucidated on the basis of spectroscopic data, mainly NMR and MS data. The absolute configuration of 1 was determined by single crystal X-ray diffraction analysis and CD anal...

journal_title：Fitoterapia

authors： Zhou WB,Zeng GZ,Xu HM,He WJ,Zhang YM,Tan NH

更新日期：2014-03-01 00:00:00

abstract：:Different lines of experimental evidence indicate that treatment with extracts from and derivatives of Phaseolus vulgaris reduces intake of food, including highly palatable foods and beverages, in rats. The present study was designed to extend to mice these lines of evidence. To this end, CD1 mice were treated acutely...

journal_title：Fitoterapia

authors： Loi B,Fantini N,Colombo G,Gessa GL,Riva A,Bombardelli E,Morazzoni P,Carai MA

更新日期：2013-03-01 00:00:00

abstract：:In our previous study, RAPD (Random Amplified Polymorphic DNA) analysis revealed species-specific markers for three medicinal Echinacea species (Asteraceae): E. angustifolia DC., E. pallida (Nutt.) Nutt. and E. purpurea (L.) Moench. In the present work, we have converted a RAPD marker (750 bp) for E. purpurea into a S...

journal_title：Fitoterapia

authors： Adinolfi B,Chicca A,Martinotti E,Breschi MC,Nieri P

更新日期：2007-01-01 00:00:00

abstract：:Three new phenylpropanoid derivatives, dasymaroacid A (1), dasymaroesters B and C (2 and 3), and one new polyoxygenated 6H-dibenzo[b,d]pyran-6-one derivative dasymarolactone D (4), together with seven known compounds (5-11), were isolated from the stems of Dasymaschalon rostratum Merr. Compounds 1 and 2 are unusual ph...

journal_title：Fitoterapia

authors： Yu ZX,Niu ZG,Li XB,Zheng CJ,Song XM,Chen GY,Song XP,Han CR,Wu SX

更新日期：2017-04-01 00:00:00

abstract：:The cardioprotective effect of Prunella vulgaris ethylacetate fraction (PVEF) and its constituent rosmarinic acid (RA) was evaluated on isolated rat cardiomyocytes subjected to doxorubicin-induced oxidative stress. The cytoprotectivities of PVEF and RA were concentration-dependent in the range of 0.005 to 0.05 mg/ml a...

journal_title：Fitoterapia

authors： Psotová J,Chlopcíková S,Miketová P,Simánek V

更新日期：2005-09-01 00:00:00

abstract：:The gastrointestinal activity of hydroalcoholic extract (HE) of Salvia officinalis was evaluated in a model of ethanol-induced gastric lesion. HE showed excellent activity, with ID(50) 84.0 (54.8-128.9) mg/kg. The acetic acid-induced ulcer and the total acidity of the gastric secretion were also reduced by HE, and, in...

journal_title：Fitoterapia

authors： Mayer B,Baggio CH,Freitas CS,dos Santos AC,Twardowschy A,Horst H,Pizzolatti MG,Micke GA,Heller M,dos Santos EP,Otuki MF,Marques MC

更新日期：2009-10-01 00:00:00

abstract：:Investigation of the fruits of Khaya senegalensis resulted in the isolation of three new mexicanolide limonoids containing a rare conjugated diene lactone system named seneganolide A (1), 2-hydroxyseneganolide A (2) and 2-acetoxyseneganolide A (3). Two known limonoids, 3-deacetyl-7-deacetoxy-7-oxokhivorin (4) and meth...

journal_title：Fitoterapia

authors： Abdelgaleil SA,Iwagawa T,Doe M,Nakatani M

更新日期：2004-09-01 00:00:00

abstract：:Two new xanthones: mangostanaxanthones I (3) and II (5) were isolated from the pericarp of Garcinia mangostana, along with four known xanthones: 9-hydroxycalabaxanthone (1), parvifolixanthone C (2), α-mangostin (4), and rubraxanthone (6). Their structures were elucidated on the basis of IR, UV, 1D, 2D NMR, and MS spec...

journal_title：Fitoterapia

authors： Mohamed GA,Ibrahim SR,Shaaban MI,Ross SA

更新日期：2014-10-01 00:00:00

abstract：:Sarcandracoumarin (1), the first coumarin having a 1-phenylethyl substituent at the C-3 position, was isolated along with eleven known phenolic compounds from the water extract of Sarcandra glabra. Its structure was elucidated on the basis of spectroscopic data. Compound 1 exhibited moderate or weak cytotoxicity again...

journal_title：Fitoterapia

authors： Feng S,Xu L,Wu M,Hao J,Qiu SX,Wei X

更新日期：2010-09-01 00:00:00

abstract：:Caesalpinone A (1), a new type of gorgonane sesquiterpenoid containing an unprecedented 1,15-bridge, along with ten known sesquiterpenoids (2-11) were isolated from the pods of Caesalpinia spinosa Kuntze (Tara). The structure of caesalpinone A was elucidated based on its 1D and 2D NMR spectra. The absolute configurati...

journal_title：Fitoterapia

authors： Mu W,Tang H,Li Y,He D,Ma R,Wang L

更新日期：2016-07-01 00:00:00

abstract：:A new sesquiterpene coumarin with a novel sesquiterpene carbon framework, Sinkiangenorin D, and ten known sesquiterpene coumarins were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds, including the relative stereochemistry, were elucidated on the basis of spectroscopic data. All of t...

journal_title：Fitoterapia

authors： Li G,Li X,Cao L,Zhang L,Shen L,Zhu J,Wang J,Si J

更新日期：2015-06-01 00:00:00

abstract：:Pocahemiketals A and B (1 and 2), two novel hemiketal sesquiterpenoids with unprecedented skeletons, were isolated from the essential oil of the aerial parts of Pogostemon cablin. In addition to a bicyclo[3.2.1]-carbon core, 1 and 2 possessed a hemiketal α,β-unsaturated-γ-lactone moiety. Their structures were determin...

journal_title：Fitoterapia

authors： Zhu H,Zhou QM,Peng C,Chen MH,Li XN,Lin DS,Xiong L

更新日期：2017-07-01 00:00:00

abstract：:Four new sesquiterpene lactones, named artemargyinolides A-D (1-4), and seven known sesquiterpenoids (5-11) were isolated from Artemisia argyi. Their structures were elucidated based on the extensive analysis of spectroscopic data. The absolute configuration of 1 was assigned by X-ray crystallographic analysis. Compou...

journal_title：Fitoterapia

authors： Zhang LB,Lv JL

更新日期：2019-11-01 00:00:00

abstract：:Gossypol is a yellow polyphenol isolated from cotton seeds. It has the antitumor activity and it is being tested to treat prostate cancer. However, its underlying mechanisms are still not well understood. The present study investigated the inhibitory effects of gossypol acetate on rat 5α-reductase 1, 3α-hydroxysteroid...

journal_title：Fitoterapia

authors： Cao S,Wang G,Ge F,Li X,Zhu Q,Ge RS,Wang Y

更新日期：2019-03-01 00:00:00

abstract：:In a two-microelectrode voltage clamp assay with Xenopus laevis oocytes, a petroleum ether extract (100 μg/mL) of the resin of Boswellia thurifera (Burseraceae) potentiated GABA-induced chloride currents (IGABA) through receptors of the subtype α₁β₂γ₂s by 319.8% ± 79.8%. With the aid of HPLC-based activity profiling, ...

journal_title：Fitoterapia

authors： Rueda DC,Raith M,De Mieri M,Schöffmann A,Hering S,Hamburger M

更新日期：2014-12-01 00:00:00

abstract：:CTPS-01, a water-soluble polysaccharide, was obtained from the root of Cudrania tricuspidata and estimated to have an average molecular weight of 5.9 x 10(3) and to be composed of glucose residues, solely. It contains an average repeating unit of decasaccharide, having a backbone consisting of 1,4-linked alpha-D-gluco...

journal_title：Fitoterapia

authors： Shi L,Fu YL,Chen KS

更新日期：2007-06-01 00:00:00

abstract：:The plants of genus Toona are well known for diverse limonoid secondary metabolites, while polyacetylenes are rarely found from Toona species. In this work, six new polyacetylenes toonasindiynes A-F (1-6) and six known analogues (7-12) were isolated from the root bark of Toona sinensis. Their structures and absolute c...

journal_title：Fitoterapia

authors： Xu WJ,Li JH,Zhou MM,Luo J,Jian KL,Tian XM,Xia YZ,Yang L,Luo J,Kong LY

更新日期：2020-10-01 00:00:00

abstract：:Effects of protopanaxdiol (PDG) and protopanaxatriol (PTG) types of ginsenosides isolated from the leaves of American ginseng on porcine pancreatic lipase activity were determined in vitro. PDG inhibited the pancreatic lipase activity in a dose-dependent manner at the concentrations of 0.25-1mg/ml. It inhibited hydrol...

journal_title：Fitoterapia

authors： Liu R,Zhang J,Liu W,Kimura Y,Zheng Y

更新日期：2010-12-01 00:00:00

abstract：:Bioassay-directed separation of the chloroform extracts from the air-dried aerial part of Alhagi pseudalhagi (M.B.) led to the isolation of a new isoflavonolignan (1), together with five known isoflavones (2-6) (Fig. 1). Their structures were identified on the basis of spectral analysis of NMR, MS, IR, UV and CD spect...

journal_title：Fitoterapia

authors： Li N,Zhang G,Xiong Y,Makhabel B,Li X,Jia X

更新日期：2010-12-01 00:00:00

abstract：:Two new natural products, 5-O-[β-D-apiofuranosyl-(1→6)-β-d-glucopyranosyl]-1-isoindolinone (1) as well as N-(2E)-3-[(2S,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-yl]acryloylglycine (2), along with four known compounds (3-6), were isolated from the methanolic extract of Co...

journal_title：Fitoterapia

authors： Fouseki MM,Damianakos H,Karikas GA,Roussakis C,P Gupta M,Chinou I

更新日期：2016-12-01 00:00:00

abstract：:The antifungal activity of methanolic extract and alkaloidal fraction of Berberis aetnensis against Candida species was investigated. The crude extract was active against Candida species, this activity being higher than that of the alkaloidal fraction and berberine. ...

journal_title：Fitoterapia

authors： Iauk L,Costanzo R,Caccamo F,Rapisarda A,Musumeci R,Milazzo I,Blandino G

更新日期：2007-02-01 00:00:00

abstract：:The isolation of jusmicranthin (1), a novel lignan from Justicia neesii, is reported. Compound 1 represents a new class of angularly fused arylnaphthalides having a gamma-hydroxylactone unit. ...

journal_title：Fitoterapia

authors： Rajasekhar D,Subbaraju GV

更新日期：2000-09-01 00:00:00

abstract：:A stimulatory effect of apigenin-6-C-β-fucopyranoside (1) on glucose uptake was observed when rat soleus muscle was incubated with 1, 10 and 100 μM of this flavonoid glycoside. The presence of specific insulin signaling inhibitors, such as wortmannin, an inhibitor of phosphoinositide 3-kinase (PI3K), RO318220, an inhi...

journal_title：Fitoterapia

authors： Cazarolli LH,Kappel VD,Pereira DF,Moresco HH,Brighente IM,Pizzolatti MG,Silva FR

更新日期：2012-10-01 00:00:00

abstract：:The cytotoxic effects of seven constituents isolated from Duguetia glabriuscula were evaluated against Hep2 human larynx carcinoma cells. The cytotoxicity exhibited by beta-sitosterol was as strong as that of cis-platin. (+)-Alloaromadendran-10,14beta-diol caused inhibition of cellular growth with IC50 values lower th...

journal_title：Fitoterapia

authors： Matos MF,Leite LI,Brustolim D,de Siqueira JM,Carollo CA,Hellmann AR,Pereira NF,da Silva DB

更新日期：2006-04-01 00:00:00

abstract：:The methanol extracts of Clematis papuasica leaves and stem bark and of Nauclea obversifolia leaves, stem and root barks showed awide spectrum of antibacterial activity which was increased on fractionation (petrol, dichloromethane, ethyl acetate), the ethyl acetate fractions being in all cases the most effective. None...

journal_title：Fitoterapia

authors： Khan MR,Kihara M,Omoloso AD

更新日期：2001-06-01 00:00:00

abstract：:The inhibitory activity of alpha-amylase and the phytochemical composition of Cedrus libani essential oils obtained from wood, leaves and cones were investigated. The C. libani woods oil exhibit an IC(50) value of 0.14 mg/ml, whereas the leaves and cones oils were devoid of any significant activity. ...

journal_title：Fitoterapia

authors： Loizzo MR,Saab AM,Statti GA,Menichini F

更新日期：2007-06-01 00:00:00

abstract：:Herbal medicines are the most globally used type of medical drugs. Their high cultural acceptability is due to the experienced safety and efficiency over centuries of use. Many of them are still phytochemically less-investigated, and are used without standardization or quality control. Choosing SIROP KILMA, an authori...

journal_title：Fitoterapia

authors： Tshitenge DT,Ioset KN,Lami JN,Ndelo-di-Phanzu J,Mufusama JP,Bringmann G

更新日期：2016-04-01 00:00:00

abstract：:A series of 33 curcumin analogues was synthesized and tested on TRPA1, TRPM8, and TRPV1 channels. Twenty of them acted as good modulators of TRPA1 channels. None was able to significantly activate TRPM8 channels, while curcumin itself and six curcuminoids belonging to the 1,3-dicarbonyl and acyclic series behaved as '...

journal_title：Fitoterapia

authors： Nalli M,Ortar G,Schiano Moriello A,Di Marzo V,De Petrocellis L

更新日期：2017-10-01 00:00:00