Jusmicranthin, a new arylnaphthalide lignan from Justicia neesii.

abstract：:Four new C18-diterpenoid alkaloids, weisaconitines A-D (1-4), were isolated from Aconitum weixiense. Based on extensive UV, IR, MS, 1D and 2D NMR analyses, their structures were elucidated as 8-O-ethyldolaconine (1), 4-demethylgenicunine B (2), 14-oxoaconosine (3), and 8-O-ethylaconosine (4). The analgesic activity of...

journal_title：Fitoterapia

authors： Zhao DK,Ai HL,Zi SH,Zhang LM,Yang SC,Guo HC,Shen Y,Chen YP,Chen JJ

更新日期：2013-12-01 00:00:00

abstract：:The gastrointestinal activity of hydroalcoholic extract (HE) of Salvia officinalis was evaluated in a model of ethanol-induced gastric lesion. HE showed excellent activity, with ID(50) 84.0 (54.8-128.9) mg/kg. The acetic acid-induced ulcer and the total acidity of the gastric secretion were also reduced by HE, and, in...

journal_title：Fitoterapia

authors： Mayer B,Baggio CH,Freitas CS,dos Santos AC,Twardowschy A,Horst H,Pizzolatti MG,Micke GA,Heller M,dos Santos EP,Otuki MF,Marques MC

更新日期：2009-10-01 00:00:00

abstract：:The pharmacological active genus Thymus L. comprises over 200 species. Besides its traditional pharmacological use, thyme may reduce the risk of caries disease, however, there is very little respective literature. The pharmacological effects can be attributed to the secondary plant metabolites. The composition of the ...

journal_title：Fitoterapia

authors： Schött G,Liesegang S,Gaunitz F,Gleß A,Basche S,Hannig C,Speer K

更新日期：2017-09-01 00:00:00

abstract：:The antinociceptive properties of the aqueous extract of Eupatorium buniifolium aerial parts were investigated in chemical and thermal models of nociception in mice. Oral doses of 250 and 500 mg/kg produced an inhibition of 42.3% and 73.9%, respectively, of the abdominal writhes induced by acetic acid in mice. This an...

journal_title：Fitoterapia

authors： Miño J,Muschietti L,Ferraro G,Martino V,Acevedo C

更新日期：2005-01-01 00:00:00

abstract：:Four meroterpenoids, applanatumols F (1), H (3), I (2), and lingzhiol (4) were isolated from the 95% EtOH extract of the fruiting bodies of Ganoderma sinense. Their structures were established on the basis of NMR spectroscopic analyses, optical rotatory dispersion data, ECD spectra, and X-ray crystallography. Compound...

journal_title：Fitoterapia

authors： Gao S,Zhang P,Zhang C,Bao F,Li H,Chen L

更新日期：2018-11-01 00:00:00

abstract：:Anti-nociceptive and anti-oedematogenic effects of the aqueous extract from the leaves of Erythrina velutina were tested through experimental models of nociception in mice and paw oedema induced by carrageenin in rats. The extract (300 and 600 mg/kg) did not change the carrageenin-induced paw oedema. In the hot plate ...

journal_title：Fitoterapia

authors： Marchioro M,Blank Mde F,Mourão RH,Antoniolli AR

更新日期：2005-12-01 00:00:00

abstract：:Gossypol is a yellow polyphenol isolated from cotton seeds. It has the antitumor activity and it is being tested to treat prostate cancer. However, its underlying mechanisms are still not well understood. The present study investigated the inhibitory effects of gossypol acetate on rat 5α-reductase 1, 3α-hydroxysteroid...

journal_title：Fitoterapia

authors： Cao S,Wang G,Ge F,Li X,Zhu Q,Ge RS,Wang Y

更新日期：2019-03-01 00:00:00

abstract：:A new sulfur-containing iridoid glucoside, named paederoside B, was isolated from the stems of Paederia scandens. The structure of the new compound was elucidated as paederosidyl paederosidate by spectral evidence. ...

journal_title：Fitoterapia

authors： Zou X,Peng S,Liu X,Bai B,Ding L

更新日期：2006-07-01 00:00:00

abstract：:Epiberberine, a natural protoberberine from Coptis chinensis Franch., is a potential alkaloid for the treatment of a variety of chronic diseases. The aim of this study is to summarize recent advances in the multiple and potential therapeutic effects of epiberberine. High-quality researches published in last two decade...

journal_title：Fitoterapia

authors： Liu L,Li J,He Y

更新日期：2020-11-01 00:00:00

abstract：:Isothiocyanates (ITCs), the breakdown products of glucosinolates found primarily in species of Brassicaceae (Cruciferae), are potential anti-cancer compounds. This review compiles data on how through different modes of action ITCs and their synthetic counterparts target leukemia. ...

journal_title：Fitoterapia

authors： Prashar A,Siddiqui F,Singh AK

更新日期：2012-03-01 00:00:00

abstract：:Bakuchicin is a furanocoumarin isolated from the seeds of Psoralea corylifolia, which is used in oriental medicine. However, limited information on the pharmacokinetics of bakuchicin is available and in addition, no determined method has been devised to quantify bakuchicin levels in the plasma. In the present study, w...

journal_title：Fitoterapia

authors： Jo JH,Kim JH,Lee HS,Jeong GS,Lee JM,Lee S

更新日期：2017-07-01 00:00:00

abstract：:Although the nature-identical chemical compounds are cheaper, they not always repeat biological activity of plant origin natural chemical compounds, often react allergies and resistance of microorganisms. The aim of this study was to investigate effects of Juniperus communis origin α-pinene with different enantiomeric...

journal_title：Fitoterapia

authors： Ložienė K,Švedienė J,Paškevičius A,Raudonienė V,Sytar O,Kosyan A

更新日期：2018-06-01 00:00:00

abstract：:The cytotoxic effects of seven constituents isolated from Duguetia glabriuscula were evaluated against Hep2 human larynx carcinoma cells. The cytotoxicity exhibited by beta-sitosterol was as strong as that of cis-platin. (+)-Alloaromadendran-10,14beta-diol caused inhibition of cellular growth with IC50 values lower th...

journal_title：Fitoterapia

authors： Matos MF,Leite LI,Brustolim D,de Siqueira JM,Carollo CA,Hellmann AR,Pereira NF,da Silva DB

更新日期：2006-04-01 00:00:00

abstract：:The isolation of a new flavan, 5,7,4'-trihydroxy-8-ethoxycarbonylflavan (1), from the root of Daphne odora var. atrocaulis is reported. ...

journal_title：Fitoterapia

authors： Zhang W,Zhang W,Li T,Liu R,Li H,Chen H

更新日期：2004-12-01 00:00:00

abstract：:Three new xanthones, cylindroxanthones A-C (1-3), were isolated from the stem bark of Garcinia cylindrocarpa. The structures were established on the basis of spectroscopic analysis. The molecular structure of 1 was unequivocally confirmed by single-crystal X-ray diffraction analysis. These three xanthones were evaluat...

journal_title：Fitoterapia

authors： Sukandar ER,Ersam T,Fatmawati S,Siripong P,Aree T,Tip-pyang S

更新日期：2016-01-01 00:00:00

abstract：:Two new triterpenoid estersaponins (1, 2) were isolated from the leaves of Pittosporum tobira 'Variegata' (Thunb.) W. T. Aiton, along with one known saponin (3) and one known flavonoid glycoside (4). Their structures were established by different spectroscopic methods including 1D and 2D NMR, UV, as well as ESI-MS ana...

journal_title：Fitoterapia

authors： El Dib RA,Eskander J,Mohamed MA,Mohammed NM

更新日期：2015-10-01 00:00:00

abstract：:The purpose of this investigation was to study the modulator and efflux pump inhibitor activity of coumarins isolated from Mesua ferrea against clinical strains as well as NorA-over expressed strain of Staphylococcus aureus 1199B. Seven coumarins were tested for modulator activity using ethidium bromide (EtBr) as a su...

journal_title：Fitoterapia

authors： Roy SK,Kumari N,Pahwa S,Agrahari UC,Bhutani KK,Jachak SM,Nandanwar H

更新日期：2013-10-01 00:00:00

abstract：:Five rare sesquiterpene lactone dimers, vlasouliolides E-I, were isolated from Vladimiria souliei. Their chemical structures were elucidated by spectroscopic analysis. Furthermore, 2 and 4 were unambiguously confirmed by Cu-Kα X-ray crystallographic analysis. Compounds 1, 2, 4 and 5 exhibited significant anti-inflamma...

journal_title：Fitoterapia

authors： Wu ZL,Wang JX,Chen LP,Dong HY,Li HL,Zhang WD

更新日期：2018-03-01 00:00:00

abstract：:Escin exerts potent glucocorticoid-like anti-inflammatory effects. The aim of this study was to investigate whether the anti-inflammatory effect of escin is through the up-regulation of glucocorticoids and if escin induces pathological changes in immune organs. Mice were administrated with escin intravenously for 7 da...

journal_title：Fitoterapia

authors： Zhang L,Wang H,Fan H,Wang T,Jiang N,Yu P,Fu F

更新日期：2011-09-01 00:00:00

abstract：:Three new monoterpene glycosides named 4-O-methyl-paeoniflorin (1), isopaeoniflorin (2), and isobenzoylpaeoniflorin (3), together with two known monoterpene glycosides, paeoniflorin (4) and benzoylpaeoniflorin (5), were isolated from the roots of Paeonia lactiflora. Their structures were established on the basis of sp...

journal_title：Fitoterapia

authors： Braca A,Kiem PV,Yen PH,Nhiem NX,Quang TH,Cuong NX,Minh CV

更新日期：2008-02-01 00:00:00

abstract：:The root of Coptis chinensis Franch. (COCH) is regularly used for medicinal purposes, and has been prescribed alone or in combination with other traditional herbs for the treatment of diabetes. To investigate the effects of COCH on glucose utilization by skeletal muscles, we prepared an ethanol extract of COCH root (C...

journal_title：Fitoterapia

authors： Yang TC,Chao HF,Shi LS,Chang TC,Lin HC,Chang WL

更新日期：2014-03-01 00:00:00

abstract：:Hydroxysafflor yellow A (HSYA) is an active ingredient obtained from the flower of Carthamus tinctorius L. The present study investigated the effects of HSYA on lipopolysaccharide (LPS)-induced inflammatory signal transduction in human alveolar epithelial A549 cells. A549 cells stimulated with LPS were incubated with ...

journal_title：Fitoterapia

authors： Song L,Zhu Y,Jin M,Zang B

更新日期：2013-01-01 00:00:00

abstract：:Four new naphthylisoquinoline alkaloids, the 5,8'-coupled ancistroyafungines A-C (1-3) and the 5,1'-linked ancistroyafungine D (4), have been isolated from the stem bark of an as yet unidentified Ancistrocladus (Ancistrocladaceae) liana recently discovered near the village Yafunga, in the North-Central region of the D...

journal_title：Fitoterapia

authors： Kavatsurwa SM,Lombe BK,Feineis D,Dibwe DF,Maharaj V,Awale S,Bringmann G

更新日期：2018-10-01 00:00:00

abstract：:The effect of schisandrin B (Sch B) on long-term ethanol-induced oxidative stress in various rat tissues was investigated. Long-term ethanol treatment increased reactive oxygen metabolites (ROM) level in plasma. The ethanol-induced oxidative stress was assessed by mitochondrial glutathione and α-tocopherol levels, ant...

journal_title：Fitoterapia

authors： Lam PY,Chiu PY,Leung HY,Chen N,Leong PK,Ko KM

更新日期：2010-12-01 00:00:00

abstract：:Three new glucosides, namely, (-)-7R8S-7',8'-dihydroxy-dihydrodehydroconiferyl alcohol-9-O-β-D-glucopyranoside (1), (+)-7S8R-7',8'-dihydroxy-dihydrodehydroconiferyl alcohol-9-O-β-D-glucopyranoside (2) and 4-hydroxy-2-methoxyphenyl 1-O-[6-(hydrogen 3-hydroxy-3-methylpentanedioate)]-β-D-glucopyranoside (3), along with 6...

journal_title：Fitoterapia

authors： Hu J,Zhao J,Khan SI,Liu Q,Liu Y,Ali Z,Li XC,Zhang SH,Cai X,Huang HY,Wang W,Khan IA

更新日期：2014-12-01 00:00:00

abstract：:The fruit rind of Garcinia gummi-gutta, commonly known as Garcinia cambogia (syn.), is extensively used traditionally as a flavourant in fish curries due to its sharp sour taste. Additional ethnobotanical uses include its use as a digestive and a traditional remedy to treat bowel complaints, intestinal parasites and r...

journal_title：Fitoterapia

authors： Semwal RB,Semwal DK,Vermaak I,Viljoen A

更新日期：2015-04-01 00:00:00

abstract：:A new cardenolide, 16,17-dihydroneridienone 3-O-beta-D-glucopyranosyl-(1-->6)-O-beta-D-galactopyranoside (1), was isolated from the roots of Terminalia arjuna. ...

journal_title：Fitoterapia

authors： Yadav RN,Rathore K

更新日期：2001-05-01 00:00:00

abstract：:CTPS-01, a water-soluble polysaccharide, was obtained from the root of Cudrania tricuspidata and estimated to have an average molecular weight of 5.9 x 10(3) and to be composed of glucose residues, solely. It contains an average repeating unit of decasaccharide, having a backbone consisting of 1,4-linked alpha-D-gluco...

journal_title：Fitoterapia

authors： Shi L,Fu YL,Chen KS

更新日期：2007-06-01 00:00:00

abstract：:A phytochemical investigation on the leaves of Tripterygium wilfordii Hook. F. was conducted, leading to the isolation of five undescribed dihydro-β-agarofuran sesquiterpenoids (1-5) and one known analogue (6). Their structures were determined by comprehensive spectroscopic analyses. The absolute configurations of the...

journal_title：Fitoterapia

authors： Zhao P,Lin B,Hou ZL,Zhou L,He QJ,Yao GD,Huang XX,Song SJ

更新日期：2020-04-01 00:00:00

abstract：:Fourteen pregnane-type steroidal alkaloids were isolated from the ethanolic extracts of whole Sarcococca hookeriana var. digyna plants. Their structures were elucidated on the basis of spectral data. Three of them were identified as new steroidal alkaloids: (S)-20-(N,N-dimethylamino)-16α,17α-epoxy-3β-methoxy-pregn-5-e...

journal_title：Fitoterapia

authors： Zhang PZ,Wang F,Yang LJ,Zhang GL

更新日期：2013-09-01 00:00:00