Abstract:
:Escin exerts potent glucocorticoid-like anti-inflammatory effects. The aim of this study was to investigate whether the anti-inflammatory effect of escin is through the up-regulation of glucocorticoids and if escin induces pathological changes in immune organs. Mice were administrated with escin intravenously for 7 days before observing the relevant parameters. The results showed that escin exhibits a potent anti-inflammatory effect, but does not increase corticosterone secretion in mice, and does not increase immune cell apoptosis in the spleen and thymus of mice. These findings suggest that the anti-inflammatory effect of escin is not dependent on the release of corticosterone.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Zhang L,Wang H,Fan H,Wang T,Jiang N,Yu P,Fu Fdoi
10.1016/j.fitote.2011.04.004subject
Has Abstractpub_date
2011-09-01 00:00:00pages
861-7issue
6eissn
0367-326Xissn
1873-6971pii
S0367-326X(11)00103-1journal_volume
82pub_type
杂志文章相关文献
FITOTERAPIA文献大全abstract::Caper (Capparis L.), a shrub plant with a large natural distribution, is used in traditional medicines to cure various illnesses. Phytochemicals studies have shown the presence of many beneficial compounds such as spermidine, rutin, quercetin, kaempferol, stigmasterol, campesterol, tocopherols, and carotenoids. Biolog...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2010.09.006
更新日期:2011-03-01 00:00:00
abstract::Investigators and sponsors of dietary supplement research need to know the relevant regulatory requirements and how to comply with them. This brief review describes how research on dietary supplements is regulated by FDA. In general, whether an FDA sanctioned Investigational New Drug (IND) application is required for ...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2010.11.011
更新日期:2011-01-01 00:00:00
abstract::The plant derived camptothecin (CPT) is a pentacyclic pyrroloquinoline alkaloid with unique antitumor activity. Successive discoveries of new CPT-producing plants occurred in recent years due to market demands. The scattered distribution among angiosperms drew researchers' attention. The aim of this review is to appra...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2019.02.014
更新日期:2019-04-01 00:00:00
abstract::Seven compounds were isolated from the roots of Eurycoma longifolia, and characterized by comprehensive analysis of 1D and 2D NMR experiments along with single crystal X-ray diffraction. Among them, four new quassinoids were identified and three of them were diastereomers for each other. Compounds 1-7 were evaluated f...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.10.009
更新日期:2014-01-01 00:00:00
abstract::A new cardenolide, 16,17-dihydroneridienone 3-O-beta-D-glucopyranosyl-(1-->6)-O-beta-D-galactopyranoside (1), was isolated from the roots of Terminalia arjuna. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(00)00337-3
更新日期:2001-05-01 00:00:00
abstract::From the roots of Smilax bockii a new compound, 7-hydroxymethyl-1, 4, 5-trihydroxynaphthalene-4-O-beta-D-xylopyranosyl(1-->6)-beta-D-glucopyranoside, was isolated. The structure of the new compound was elucidated on the basis of spectroscopic methods. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2008.03.009
更新日期:2008-09-01 00:00:00
abstract::This investigation focuses on the in vitro neuroactive properties of pinostrobin, a substituted flavanone from Cajanus cajan (L.) Millsp. of the Fabaceae family. We demonstrate that pinostrobin inhibits voltage-gated sodium channels of mammalian brain (IC(50)=23 µM) based on the ability of this substance to suppress t...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2010.05.005
更新日期:2010-10-01 00:00:00
abstract::Three new cycloartane triterpenoids (1-3) and two known compounds (4, 5) were isolated from the whole plant of Beesia calthaefolia. Their structures were elucidated by 1D and 2D NMR, HRESIMS and optical rotation spectral data. All isolates were investigated for their inhibitory effects on the classical pathway of the ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.10.005
更新日期:2014-01-01 00:00:00
abstract::Human carboxylesterase 1 (CES1), primarily expressed in the liver and adipocytes, is responsible for the hydrolysis of endogenous esters (such as cholesteryl esters and triacylglycerols) and the metabolism of xenobiotic esters (such as clopidogrel and oseltamivir), thus participates in physiological and pathological p...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2019.104199
更新日期:2019-09-01 00:00:00
abstract::Ganoderma cochlear, as edible and medicinal fungus, has long been used to prevent and treat various diseases. As our continuously phytochemical investigation of this fungus, a HPLC-UV-guided method led to the isolation of nine previously undescribed aromatic meroterpenoids with different ring systems, including six pa...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2018.03.005
更新日期:2018-06-01 00:00:00
abstract::Seven new lignans, cleistonkinins A- E (1-5), cleistonkisides A and B (6-7) were isolated from the fruits of Cleistanthus tonkinensis (Euphorbiaceae), together with five known aryltetralin lignans, cleisindoside B (8), cleistantoxin (9), cleisindoside D (10), neocleistantoxin (11) and polygamain (12). Their structures...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2019.104432
更新日期:2020-01-01 00:00:00
abstract::This paper reports the results of an ethnobotanical survey of medicinal plants used by the Thari people of the Nara Desert, Sindh, Pakistan. Fifty-one plant species distributed across 28 families and 43 genera were discovered to have medicinal uses by local inhabitants of the Nara Desert. Twenty-one of those species a...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2008.03.010
更新日期:2008-09-01 00:00:00
abstract::The phytochemical profile, antioxidant activity and α-glucosidase inhibitory activity of Hypericum scruglii Bacchetta, Brullo et Salmeri and Hypericum hircinum L. were analyzed and compared to those of the best-known Hypericum perforatum L. Samples were prepared using three different extraction methods (maceration in ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2017.06.020
更新日期:2017-07-01 00:00:00
abstract::Three new phloroglucinols, baeckenones D-F (1-3), were obtained from the leaves of Indonesian Baeckea frutescens, along with the known unusual endoperoxide, phloroglucinol (4). The structures of the isolated compounds were elucidated by 1D and 2D NMR and HREIMS spectra. Furthermore, the stereochemistry of baeckenone D...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.01.013
更新日期:2016-03-01 00:00:00
abstract::Five new 2-(2-phenylethyl)chromone derivatives (1-5), along with eleven known compounds (6-16) were isolated from Chinese agarwood. Their structures were elucidated by spectroscopic data (NMR, UV, IR, and MS) analyses and comparison of their spectroscopic and physical data with the literature values. The absolute conf...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2017.02.009
更新日期:2017-04-01 00:00:00
abstract::Hepatitis C virus (HCV) infection is highly prevalent among global populations, with an estimated number of infected patients being 170 million. Approximately 70-80% of patients acutely infected with HCV will progress to chronic liver disease, such as liver cirrhosis and hepatocellular carcinoma, which is a substantia...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2014.10.011
更新日期:2014-12-01 00:00:00
abstract::Dragon's blood is a rare and precious traditional medicine used by different cultures since ancient times. However, studies on enhancing the rapid accumulation of dragon's blood in Dracaena cambodiana and determining its formation mechanism are unavailable. In this study, the activities of two fungi, namely, BJDC01 an...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.03.012
更新日期:2013-06-01 00:00:00
abstract::A new arylnaphthalene lignan, named furfuracin, was isolated from the leaves of Knema furfuracea (Myristicaceae), whereas 7 known compounds including (+)-trans-1,2-dihydrodehydroguaiaretic acid, fragransin A(2), biochanin A, gingkolic acid, anarcardic acid, 2-hydroxy-6-(12-phenyldodecyl)-benzoic acid and 2-hydroxy-6-(...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2009.05.005
更新日期:2009-09-01 00:00:00
abstract::7-O-methylvariecolortide A (1), variecolortide B (2), and variecolortide C (3), the rare variecolortides existing in racemic manner, were isolated from an endolichenic fungal strain Eurotium sp. (No. 17-11-8-1). With the chiral HPLC technology, (-)-(S)-7-O-methylvariecolortide A (1a), (+)-(R)-7-O-methylvariecolortide ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.11.012
更新日期:2014-01-01 00:00:00
abstract::A series of 33 curcumin analogues was synthesized and tested on TRPA1, TRPM8, and TRPV1 channels. Twenty of them acted as good modulators of TRPA1 channels. None was able to significantly activate TRPM8 channels, while curcumin itself and six curcuminoids belonging to the 1,3-dicarbonyl and acyclic series behaved as '...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2017.09.007
更新日期:2017-10-01 00:00:00
abstract::Hydroxysafflor yellow A (HSYA) is an active ingredient obtained from the flower of Carthamus tinctorius L. The present study investigated the effects of HSYA on lipopolysaccharide (LPS)-induced inflammatory signal transduction in human alveolar epithelial A549 cells. A549 cells stimulated with LPS were incubated with ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.11.004
更新日期:2013-01-01 00:00:00
abstract::Eighteen alkaloids were detected in the bark, leaves, wood and roots of Peumus boldus, including traces of secoboldine, N-methylsecoboldine (boldine methine), glaucine and norreticuline, not reported previously as constituents of this species. Using appropriate standards, we quantified thirteen of them by UHPLC-MS/MS....
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2018.02.020
更新日期:2018-06-01 00:00:00
abstract::Combinations of thyme, cowslip and liquorice roots are often used in the treatment of upper respiratory tract infections. Therefore the volatile fraction of herbal teas prepared from thyme (Thymus vulgaris) and the effect of combining with cowslip (Primula veris/P. elatior) and liquorice roots (Glycyrrhiza glabra) on ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2011.05.006
更新日期:2011-09-01 00:00:00
abstract::The last few decades have seen an alarming rise in fungal infections, which currently represent a global health threat. Despite extensive research towards the development of new antifungal agents, only a limited number of antifungal drugs are available in the market. The routinely used polyene agents and many azole an...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2016.05.016
更新日期:2016-07-01 00:00:00
abstract::Diabetes is a worldwide healthy concern, which affects approximately 9% of the population. Tetrahydrocurcumin (THC) is the main metabolite of curcumin, which exerts the anti-diabetic activity. However, the underlying mechanism has not been clarified. In the research, we investigated whether THC could improve diabetes ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2020.104665
更新日期:2020-10-01 00:00:00
abstract::Ethanolic extract of Rungia repens aerials parts (300 and 600 mg/kg p.o) showed diuretic activity in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2005.11.007
更新日期:2006-02-01 00:00:00
abstract::Extracts of the leaves of Securinega leucopyrus exhibited a broad spectrum of antimicrobial activity. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(01)00341-0
更新日期:2001-12-01 00:00:00
abstract::Two new neo-clerodane diterpenoids have been isolated from the whole plant of Scutellaria barbata D. Don, and their structures were established by detailed spectral analyses as scutehenanine H (1) and 6-(2,3-epoxy-2-isopropyl-n-propoxyl)barbatin C (2). In vitro, the isolated two new compounds showed significant cytoto...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2010.01.001
更新日期:2010-10-01 00:00:00
abstract::Different lines of experimental evidence indicate that treatment with extracts from and derivatives of Phaseolus vulgaris reduces intake of food, including highly palatable foods and beverages, in rats. The present study was designed to extend to mice these lines of evidence. To this end, CD1 mice were treated acutely...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.12.015
更新日期:2013-03-01 00:00:00
abstract::Two new isocoumarins (1 and 2), a new alkaloid (3), and a known N-acetyldopamine dimer (4) were isolated from the ethyl acetate extract of Chinese insect medicine Eupolyphaga sinensis. Their structures were elucidated on the basis of detailed spectroscopic investigations, such as 1D- and 2D NMR spectroscopy, as well a...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.06.005
更新日期:2012-10-01 00:00:00