New neo-clerodane diterpenoids from Scutellaria barbata with cytotoxic activities.

abstract：:Four new cycloartane triterpenoids, 1α,3β-dihydroxy-16-keto-24(31)-en-cycloartane (1), 31-methoxyl-passifloic acid (2), cyclopassifloside XIV (3), and cyclopassifloside XV (4), together with six known compounds (5-10) were isolated from Passiflora edulis Sims. Their structures were elucidated on the basis of extensive...

journal_title：Fitoterapia

authors： Xu FQ,Wang N,Fan WW,Zi CT,Zhao HS,Hu JM,Zhou J

更新日期：2016-12-01 00:00:00

abstract：:The flavonoids are a heterogeneous group of ubiquitous plant polyphenols that abound in the human diet and are endowed with several biological activities, including immunomodulating and antioxidant activities. The bioactivity of flavonoids is tightly correlated with their chemical structure and action mechanisms, most...

journal_title：Fitoterapia

authors： Ielpo MT,Basile A,Miranda R,Moscatiello V,Nappo C,Sorbo S,Laghi E,Ricciardi MM,Ricciardi L,Vuotto ML

更新日期：2000-08-01 00:00:00

abstract：:Five new steroids, colebrin A-E (1-5) were isolated from the aerial parts of Clerodendrum colebrookianum. The structures of the new compounds were elucidated on the basis of spectral evidence. ...

journal_title：Fitoterapia

authors： Yang H,Wang J,Hou AJ,Guo YP,Lin ZW,Sun HD

更新日期：2000-12-01 00:00:00

abstract：:The alkaloidal fraction obtained from an ethanolic extract of the leaves of Mikania cordata exhibited significant in vivo antiulcer activity in diclofenac sodium-induced gastric erosions in Long Evans rats. ...

journal_title：Fitoterapia

authors： Paul RK,Jabbar A,Rashid MA

更新日期：2000-12-01 00:00:00

abstract：:Since the extract from berries of Aronia melanocarpa presents antioxidative properties in plasma and in blood platelets, not only from healthy group, but also from patients with benign breast diseases and in patients with invasive breast cancer before surgery, the aim of our present study was to evaluate the oxidative...

journal_title：Fitoterapia

authors： Kedzierska M,Olas B,Wachowicz B,Glowacki R,Bald E,Czernek U,Szydłowska-Pazera K,Potemski P,Piekarski J,Jeziorski A

更新日期：2012-03-01 00:00:00

abstract：:A phytochemical fractionation of the methanol extract of the Morus alba leaves led to the isolation of eleven flavonoids (1-11). The structure of the new 3'-geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone (1) was elucidated by means of spectroscopic methods. The cytotoxicity of the isolated compounds against human cerv...

journal_title：Fitoterapia

authors： Dat NT,Binh PT,Quynh le TP,Van Minh C,Huong HT,Lee JJ

更新日期：2010-12-01 00:00:00

abstract：:Fractions prepared from the methanol extract of Buchholzia coriacea stem bark exhibited a high concentration-dependent antibacterial and antifungal activity compared to the standard antibiotics, ampicillin and tioconazole. In the brine shrimp lethality (BSL) assay, the methanol extract was found to be non-toxic with a...

journal_title：Fitoterapia

authors： Ajaiyeoba EO,Onocha PA,Nwozo SO,Sama W

更新日期：2003-12-01 00:00:00

abstract：:Two new dimeric diarylheptanoids, named Alpinin C (1) and D (2), a new natural product of diarylheptanoid (3) along with three known diarylheptanoids (4-6) were isolated from the rhizomes of Alpinia officinarum Hance. Their structures were elucidated based on extensive spectroscopic analyses (1D and 2D NMR, HRTOFMS, I...

journal_title：Fitoterapia

authors： Liu D,Liu YW,Guan FQ,Liang JY

更新日期：2014-07-01 00:00:00

abstract：:The antioxidant properties of six medical herbs used in the traditional Paraguayan medicine were studied using free radical-generating systems. The methanol extracts from Aristolochia giberti, Cecropia pachystachya, Eugenia uniflora, Piper fulvescens, Schinus weinmannifolia and Schinus terebinthifolia protected agains...

journal_title：Fitoterapia

authors： Velázquez E,Tournier HA,Mordujovich de Buschiazzo P,Saavedra G,Schinella GR

更新日期：2003-02-01 00:00:00

abstract：:Biomass and secondary metabolite accumulation were assayed on a wide range of auxins, cytokinins and their combinations using Ecballium elaterium callus tissue. The best combination was that consisting of alpha-naphthalene acetic acid (NAA) and benzylamino purine (BAP) (1 mg/l of medium, each). NAA and BAP were set up...

journal_title：Fitoterapia

authors： Attard EG,Scicluna-Spiteri A

更新日期：2001-01-01 00:00:00

abstract：:Two novel 2-arylbenzofuran dimers, shandougenines A (1) and B (2), and two new polyisoprenylated flavanones 3 (shandougenine C) and 4 (shandougenine D) were isolated from the 95% EtOH extract of Sophora tonkinensis, together with 18 known compounds. Their structures were determined on the basis of spectral data interp...

journal_title：Fitoterapia

authors： Luo G,Yang Y,Zhou M,Ye Q,Liu Y,Gu J,Zhang G,Luo Y

更新日期：2014-12-01 00:00:00

abstract：:Calcium-activated chloride channels (CaCCs) as a kind of widely expressed ion channels play crucial roles in a variety of physiological regulation. TMEM16A has been identified as the molecular basis of CaCCs in numerous cell types and is considered a new drug target for many diseases. Regulating the function of TMEM16...

journal_title：Fitoterapia

authors： Zhu X,Zhang W,Jin L,Zhang G,Yang H,Yu B

更新日期：2020-11-01 00:00:00

abstract：:Tithonia diversifolia (Asteraceae), is used as traditional medicine in tropical countries for the treatment of various diseases, including malaria. Although numerous studies have assessed the antimalarial properties, nothing is known about the effect of T. diversifolia extracts on trypanosomiasis. In this study extrac...

journal_title：Fitoterapia

authors： Sut S,Dall'Acqua S,Baldan V,Ngahang Kamte SL,Ranjbarian F,Biapa Nya PC,Vittori S,Benelli G,Maggi F,Cappellacci L,Hofer A,Petrelli R

更新日期：2018-01-01 00:00:00

abstract：:Two new glycosides, 2-methyl-L-erythritol-4-O-(6-O-trans-sinapoyl)-β-D-glucopyranoside (1) and 2-methyl-L-erythritol-1-O-(6-O-trans-sinapoyl)-β-D-glucopyranoside (2), along with two known triterpenoids (3-4), four quinic acid derivatives (5-8) and one flavonoid (9) were isolated from the fruit of Gardenia jasminoides....

journal_title：Fitoterapia

authors： Yang L,Peng K,Zhao S,Zhao F,Chen L,Qiu F

更新日期：2013-09-01 00:00:00

abstract：:A new sesquiterpene coumarin with a novel sesquiterpene carbon framework, Sinkiangenorin D, and ten known sesquiterpene coumarins were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds, including the relative stereochemistry, were elucidated on the basis of spectroscopic data. All of t...

journal_title：Fitoterapia

authors： Li G,Li X,Cao L,Zhang L,Shen L,Zhu J,Wang J,Si J

更新日期：2015-06-01 00:00:00

abstract：:Two new natural products, 5-O-[β-D-apiofuranosyl-(1→6)-β-d-glucopyranosyl]-1-isoindolinone (1) as well as N-(2E)-3-[(2S,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-yl]acryloylglycine (2), along with four known compounds (3-6), were isolated from the methanolic extract of Co...

journal_title：Fitoterapia

authors： Fouseki MM,Damianakos H,Karikas GA,Roussakis C,P Gupta M,Chinou I

更新日期：2016-12-01 00:00:00

abstract：:Cranberry procyanidins and quercetin derivatives are considered possible active compounds against urinary tract infections (UTIs). In this paper a small group (n=6) of healthy subjects consumed a product containing 360mg of cranberry extract (42.6% w/w of PAC-A and 14.6% w/w of PAC-B) and 200mg of quercetin. Urine sam...

journal_title：Fitoterapia

authors： Peron G,Sut S,Pellizzaro A,Brun P,Voinovich D,Castagliuolo I,Dall'Acqua S

更新日期：2017-10-01 00:00:00

abstract：:Curcuphenol is a sesquiterpene isolated from sponges and plants having several significant biological activities. The present study explored its effect on cell proliferation and apoptosis in Caco-2 human colon cancer cells. It was demonstrated that curcuphenol in concentrations in the range of 29-116 µg/ml inhibited c...

journal_title：Fitoterapia

authors： Rodrigo G,Almanza GR,Cheng Y,Peng J,Hamann M,Duan RD,Akesson B

更新日期：2010-10-01 00:00:00

abstract：:Four new taraxerane triterpenoids, 1β,3β-dihydroxy-11α,12α-oxidotaraxerane (1), 28-hydroxy-11α,12α-oxidotaraxerane-3-one (2), 3β-hydroxy-11α,12α-oxidotaraxerane-28-al (3), and 3-O-acetyl-11α,12α-oxidotaraxerane-28-al (4), together with three known compounds 3β-hydroxy-11α,12α-oxidotaraxerane (5), 3β,28-dihydroxy-11α,1...

journal_title：Fitoterapia

authors： Hu J,Shi X,Chen J,Huang H,Zhao C

更新日期：2012-01-01 00:00:00

abstract：:The estrogenicity of different batches of red clover (Trifolium pratense L., Fabaceae; RCL) extracts and its relationship with the isoflavone content were assessed by measuring MCF-7 cell proliferation by flow cytometry and propidium iodide staining. RCL extracts were compared to estradiol (E2) and to the main RCL iso...

journal_title：Fitoterapia

authors： Spagnuolo P,Rasini E,Luini A,Legnaro M,Luzzani M,Casareto E,Carreri M,Paracchini S,Marino F,Cosentino M

更新日期：2014-04-01 00:00:00

abstract：:The fruits of Piper tuberculatum Jacq yielded piperine S (1) and N-(12,13,14-trimethoxydihydrocinnamoyl)-delta(3)-piperidin-2-one (2). Their complete NMR analysis based on one- and two-dimensional experiments is reported. ...

journal_title：Fitoterapia

authors： de O Chaves MC,de F Júnior AG,de O Santos BV

更新日期：2003-02-01 00:00:00

abstract：:Phytochemical study on rhizomes of Cimicifuga dahurica resulted in the isolation of nine new neolignan and phenylpropanoid glycosides, cimicifugasides A-E (1, 2, 7-9), cimicifugamides B-D (3-5), shomaside G (6) along with four known compounds (10-13). Their structures were identified by extensive spectroscopic analyse...

journal_title：Fitoterapia

authors： Lu Q,Zhang WY,Pan DB,Shi DF,Pang QQ,Li HB,Yao XJ,Yao ZH,Yu Y,Yao XS

更新日期：2019-04-01 00:00:00

abstract：:Oplopanax horridus or devil's club is a herbal medicine distributed in North America. The constituents and pharmacological activities of O. horridus (OPH) are largely unknown. In this study, we assayed OPH stem and berry extracts using high performance liquid chromatography (HPLC). The anticancer potentials of extract...

journal_title：Fitoterapia

authors： Wang CZ,Aung HH,Mehendale SR,Shoyama Y,Yuan CS

更新日期：2010-03-01 00:00:00

abstract：:Besides the unquestionable positive effects of solar exposure for human health, UV rays have been widely investigated for toxicology aspects related to excessive UVB and UVA doses, which involve sunburns, skin aging, DNA skin damage and tumorigenesis. At present, synthetic and mineral sunscreens are used to protect ag...

journal_title：Fitoterapia

authors： Radice M,Manfredini S,Ziosi P,Dissette V,Buso P,Fallacara A,Vertuani S

更新日期：2016-10-01 00:00:00

abstract：:Dragon's blood is a rare and precious traditional medicine used by different cultures since ancient times. However, studies on enhancing the rapid accumulation of dragon's blood in Dracaena cambodiana and determining its formation mechanism are unavailable. In this study, the activities of two fungi, namely, BJDC01 an...

journal_title：Fitoterapia

authors： Cui JL,Wang CL,Guo SX,Xiao PG,Wang ML

更新日期：2013-06-01 00:00:00

abstract：:Herbal medicines are the most globally used type of medical drugs. Their high cultural acceptability is due to the experienced safety and efficiency over centuries of use. Many of them are still phytochemically less-investigated, and are used without standardization or quality control. Choosing SIROP KILMA, an authori...

journal_title：Fitoterapia

authors： Tshitenge DT,Ioset KN,Lami JN,Ndelo-di-Phanzu J,Mufusama JP,Bringmann G

更新日期：2016-04-01 00:00:00

abstract：:Oral treatment with the water extracts of Scoparia dulcis whole aerial parts, at doses of 50, 100 and 200 mg/kg, dose dependently inhibited the indomethacin-induced gastric damages in rats. ...

journal_title：Fitoterapia

authors： Babincová M,Schronerová K,Sourivong P

更新日期：2008-12-01 00:00:00

abstract：:The antioxidant activity of Citrus paradisi (grapefruit) seeds glyceric extract dissolved in ethanol and in aqueous media was evaluated using three different methods: evaluation by DPPH assay, by 5-lipoxygenase assay and by luminol/xanthine/xanthine oxidase chemiluminescence assay. The total phenolic content was deter...

journal_title：Fitoterapia

authors： Giamperi L,Fraternale D,Bucchini A,Ricci D

更新日期：2004-03-01 00:00:00

abstract：:Nagilactones are norditerpene dilactones isolated from the root bark of Podocarpus nagi. Although nagilactone E has been reported to show antifungal activities, its activity is weaker than that of antifungals on the market. Nagilactone E enhances the antifungal activity of phenylpropanoids such as anethole and isosafr...

journal_title：Fitoterapia

authors： Hayashi K,Yamaguchi Y,Ogita A,Tanaka T,Kubo I,Fujita KI

更新日期：2018-07-01 00:00:00

abstract：:A new coumestan, 1,3,9-trihydroxy-8-methoxycoumestan, named flemicoumestan A 1 together with nine isoflavone-related compounds were isolated from the ethyl acetate extract of the roots of Flemingia philippinensis. Their structures were elucidated and confirmed by spectroscopic methods and literature data. Compounds 3 ...

journal_title：Fitoterapia

authors： Li L,Deng X,Zhang L,Shu P,Qin M

更新日期：2011-06-01 00:00:00