当前位置： SCI文献检索 > FITOTERAPIA期刊下所有文献 > Antiproliferative effects of curcuphenol, a sesquiterpene phenol.

Antiproliferative effects of curcuphenol, a sesquiterpene phenol.

Abstract：

:Curcuphenol is a sesquiterpene isolated from sponges and plants having several significant biological activities. The present study explored its effect on cell proliferation and apoptosis in Caco-2 human colon cancer cells. It was demonstrated that curcuphenol in concentrations in the range of 29-116 µg/ml inhibited cell proliferation and DNA replication and induced cell death in a dose-dependent manner. The induction of apoptosis was associated with a stimulation of the activity of caspase-3. The findings presented here suggest that curcuphenol has antiproliferative and pro-apoptotic properties.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Rodrigo G,Almanza GR,Cheng Y,Peng J,Hamann M,Duan RD,Akesson B

doi

10.1016/j.fitote.2010.04.001

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

762-6

issue

7

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(10)00079-1

journal_volume

81

pub_type

杂志文章

相关文献

FITOTERAPIA文献大全
  • Cycloartane triterpenes from Beesia calthaefolia (Maxim.).

    abstract：:Three new cycloartane triterpenoids (1-3) and two known compounds (4, 5) were isolated from the whole plant of Beesia calthaefolia. Their structures were elucidated by 1D and 2D NMR, HRESIMS and optical rotation spectral data. All isolates were investigated for their inhibitory effects on the classical pathway of the ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2013.10.005

    authors： Mu LH,Li HJ,Guo DH,Zhao JY,Liu P

    更新日期：2014-01-01 00:00:00

  • Biological activity of some Patagonian plants.

    abstract：:Citotoxicity (inhibition of cell division in fertilized eggs of Loxechinus albus) and general toxicity (using embryos of Artemia salina) of plants belonging to the genera Senecio, Deschampsia, Alstroemeria, Anarthrophyllum, Chloraea and Geranium were investigated. ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2005.07.007

    authors： Cuadra P,Furrianca M,Oyarzún A,Yáñez E,Gallardo A,Fajardo V

    更新日期：2005-12-01 00:00:00

  • Triterpenoid saponins from the roots of Psammosilene tunicoides.

    abstract：:Seven oleanane-type triterpenoid saponins, tunicosaponins B-D (1-3), F-I (4-7), along with eight known triterpenoid saponins (8-15), were isolated from the roots of Psammosilene tunicoides. The structures of compounds 1-7 were determined by comprehensive spectroscopic analysis, including 1D and 2D NMR techniques, mass...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2020.104596

    authors： Wen B,Tian JM,Huang ZR,Xiao SJ,Yuan WL,Wang JX,Li HL,Xu XK,Shen YH

    更新日期：2020-07-01 00:00:00

  • Geranylated 2-arylbenzofurans from Morus alba var. tatarica and their α-glucosidase and protein tyrosine phosphatase 1B inhibitory activities.

    abstract：:Ten new geranylated 2-arylbenzofuran derivatives, including two monoterpenoid 2-arylbenzofurans (1 and 2), two geranylated 2-arylbenzofuran enantiomers (3a and 3b), and six geranylated 2-arylbenzofurans (4-9), along with four known 2-arylbenzofurans (10-13) were isolated from the root bark of Morus alba var. tatarica....

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2013.10.017

    authors： Zhang YL,Luo JG,Wan CX,Zhou ZB,Kong LY

    更新日期：2014-01-01 00:00:00

  • Five new sesquiterpenoids from Dalbergia odorifera.

    abstract：:Five new sesquiterpenes (1-5) along with ten known ones were isolated from the heartwood of Dalbergia odorifrea T. Chen. Their structures were determined by spectroscopic techniques including MS, UV, IR, 1D and 2D NMR. Bioassay results showed that compounds 1 and 9 had inhibitory effect on Candida albicans, and compou...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2014.02.013

    authors： Wang H,Dong WH,Zuo WJ,Liu S,Zhong HM,Mei WL,Dai HF

    更新日期：2014-06-01 00:00:00

  • Antifungal activity of the methanolic extract and alkaloids of Glaucium oxylobum.

    abstract：:The methanolic extract and total alkaloids of the aerial parts of Glaucium oxylobum exhibited good activity against Microsporum gypseum, Microsporum canis, Trichophyton mentagrophytes and Epidermophyton floccosum. Four alkaloids, dicentrine, glaucine, protopine, and alpha-allocryptopine, were identified as the compoun...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/s0367-326x(03)00113-8

    authors： Morteza-Semnani K,Amin G,Shidfar MR,Hadizadeh H,Shafiee A

    更新日期：2003-07-01 00:00:00

  • Sesquiterpenoids from Artemisia argyi and their COXs inhibitory activities.

    abstract：:Four new sesquiterpene lactones, named artemargyinolides A-D (1-4), and seven known sesquiterpenoids (5-11) were isolated from Artemisia argyi. Their structures were elucidated based on the extensive analysis of spectroscopic data. The absolute configuration of 1 was assigned by X-ray crystallographic analysis. Compou...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2019.104372

    authors： Zhang LB,Lv JL

    更新日期：2019-11-01 00:00:00

  • Tricycloalternarenes F-H: three new mixed terpenoids produced by an endolichenic fungus Ulocladium sp. using OSMAC method.

    abstract：:Three new mixed terpenoids, tricycloalternarenes (TCAs) F-H (1-3), together with ten known tricycloalternarenes (4-13), were isolated from the Czapek's culture of an endophytic fungus Ulocladium sp. Their structures were identified by extensive spectroscopic experiments (NMR and MS) and comparison with literature data...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2012.12.029

    authors： Wang QX,Bao L,Yang XL,Guo H,Ren B,Guo LD,Song FH,Wang WZ,Liu HW,Zhang LX

    更新日期：2013-03-01 00:00:00

  • New ursane-type triterpenoids from Clerodendranthus spicatus.

    abstract：:Five new ursane-type triterpenoids, spicatusoids A-E (1, 3-6), and three known ones (2, 7, and 8), and a known oleanane-type triterpenoid (9) were isolated from the aerial parts of Clerodendranthus spicatus. Their structures were elucidated by spectroscopic methods. In particular, the structure of 3 including its abso...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2017.04.001

    authors： Luo Y,Cheng LZ,Luo Q,Yan YM,Wang SM,Sun Q,Cheng YX

    更新日期：2017-06-01 00:00:00

  • A new coumestan with immunosuppressive activities from Flemingia philippinensis.

    abstract：:A new coumestan, 1,3,9-trihydroxy-8-methoxycoumestan, named flemicoumestan A 1 together with nine isoflavone-related compounds were isolated from the ethyl acetate extract of the roots of Flemingia philippinensis. Their structures were elucidated and confirmed by spectroscopic methods and literature data. Compounds 3 ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2011.01.019

    authors： Li L,Deng X,Zhang L,Shu P,Qin M

    更新日期：2011-06-01 00:00:00

  • Anti-nociceptive activity of the aqueous extract of Erythrina velutina leaves.

    abstract：:Anti-nociceptive and anti-oedematogenic effects of the aqueous extract from the leaves of Erythrina velutina were tested through experimental models of nociception in mice and paw oedema induced by carrageenin in rats. The extract (300 and 600 mg/kg) did not change the carrageenin-induced paw oedema. In the hot plate ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2005.07.002

    authors： Marchioro M,Blank Mde F,Mourão RH,Antoniolli AR

    更新日期：2005-12-01 00:00:00

  • New alkaloidal metabolites from cultures of entomopathogenic fungus Cordyceps takaomontana NBRC 101754.

    abstract：:Two new alkaloidal metabolites, cordytakaoamides A (1) and B (2), as well as, 2-[(2-hydroxyethyl) amino] benzoic acid (3) and 2E-decenamide (4), and three known compounds (5-7) were isolated from ethyl acetate and n-butanol soluble portions of the entomopathogenic fungus, Cordyceps takaomontana NBRC 101754. Compounds ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2019.104364

    authors： Hama M,Elshamy AI,Yoneyama T,Kasai Y,Yamamoto H,Tanigawa K,Oshiro A,Noji M,Ban S,Imagawa H,Umeyama A

    更新日期：2019-11-01 00:00:00

  • Steroidal saponins from the leaves of Agave macroacantha.

    abstract：:A new monodesmosidic spirostanol saponin, along with three known saponins was isolated from Agave macroacantha Zucc leaves. The structure of the new saponin was established as hecogenin-3-O-alpha-L-rhamnopyranosyl (1-->4) beta-D-xylopyranosyl (1-->3)[beta-D-glucopyranosyl (1-->2)] beta-D-glucopyranosyl (1-->4) beta-D-...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2009.11.002

    authors： Eskander J,Lavaud C,Harakat D

    更新日期：2010-07-01 00:00:00

  • A new flavan from Daphne odora var. atrocaulis.

    abstract：:The isolation of a new flavan, 5,7,4'-trihydroxy-8-ethoxycarbonylflavan (1), from the root of Daphne odora var. atrocaulis is reported. ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2004.09.014

    authors： Zhang W,Zhang W,Li T,Liu R,Li H,Chen H

    更新日期：2004-12-01 00:00:00

  • Alkaloids from Coptis chinensis root promote glucose uptake in C2C12 myotubes.

    abstract：:The root of Coptis chinensis Franch. (COCH) is regularly used for medicinal purposes, and has been prescribed alone or in combination with other traditional herbs for the treatment of diabetes. To investigate the effects of COCH on glucose utilization by skeletal muscles, we prepared an ethanol extract of COCH root (C...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2014.01.008

    authors： Yang TC,Chao HF,Shi LS,Chang TC,Lin HC,Chang WL

    更新日期：2014-03-01 00:00:00

  • Polyphenolic profile and biological activities of black carrot crude extract (Daucus carota L. ssp. sativus var. atrorubens Alef.).

    abstract：:Black carrot (Daucus carota L. ssp. sativus var. atrorubens Alef.) is a valuable source of carbohydrates, minerals and vitamins and contains also high amounts of anthocyanins giving the characteristic deep-purple color. These latter compounds are known as natural dyes used in the food and pharmaceutical industry that ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2017.10.006

    authors： Smeriglio A,Denaro M,Barreca D,D'Angelo V,Germanò MP,Trombetta D

    更新日期：2018-01-01 00:00:00

  • Acute toxicity and diuretic studies of Rungia repens aerial parts in rats.

    abstract：:Ethanolic extract of Rungia repens aerials parts (300 and 600 mg/kg p.o) showed diuretic activity in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg. ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2005.11.007

    authors： Basu SK,Arivukkarasu R

    更新日期：2006-02-01 00:00:00

  • Five new koumine-type alkaloids from the roots of Gelsemium elegans.

    abstract：:Five new koumine-type alkaloids (1-5) along with six known ones were isolated from the roots of Gelsemium elegans. Their structures with absolute configurations were elucidated on the basis of NMR spectroscopy and electronic circular dichroism spectral analyses. The inhibitory effects of compounds 1-11 on the viabilit...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2017.03.004

    authors： Zhang W,Zhang SY,Wang GY,Li NP,Chen MF,Gu JH,Zhang DM,Wang L,Ye WC

    更新日期：2017-04-01 00:00:00

  • Flavonoids and stilbenoids from Derris eriocarpa.

    abstract：:One new resveratrol analogue, 1-(3',4',5'-trimethoxyphenyl)-2-methoxy-2-(4″-methoxyphenyl)-ethane-1-ol (1), and two new prenylisoflavones, 4'-hydroxy-5,7-dimethoxy-6-(3-methyl-2-butenyl)-isoflavone (2), and derrubon 5-methyl ether (3), together with 17 known compounds including one new natural product, 5,7-dihydroxy-3...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2014.03.015

    authors： Zhang HX,Lunga PK,Li ZJ,Dai Q,Du ZZ

    更新日期：2014-06-01 00:00:00

  • Oleanene constituents of Lantana cujabensis.

    abstract：:A new compound, 3beta,25-epoxy-3alpha-hydroxy-22beta-isobutanoyloxyolean-12-ene-28-oic acid (1), and two known triterpenoids lantanilic acid (2) and camaric acid (3) were isolated from the stem and leaves of Lantana cujabensis. Their structures were elucidated by spectroscopic methods. The ethanol extracts did not sho...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2004.02.005

    authors： Okunade AL,Lewis WH

    更新日期：2004-06-01 00:00:00

  • Antimicrobial activity of Hymenodictyon parvifolium.

    abstract：:Methanol extract of the stem bark of Hymenodictyon parvifolium was tested for its antifungal and antibacterial activity. The extract was found to have inhibitory effect against all the pathogens tested. ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/s0367-326x(02)00176-4

    authors： Kariba RM

    更新日期：2002-10-01 00:00:00

  • Antinociceptive activity of Eupatorium buniifolium aqueous extract.

    abstract：:The antinociceptive properties of the aqueous extract of Eupatorium buniifolium aerial parts were investigated in chemical and thermal models of nociception in mice. Oral doses of 250 and 500 mg/kg produced an inhibition of 42.3% and 73.9%, respectively, of the abdominal writhes induced by acetic acid in mice. This an...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2004.10.009

    authors： Miño J,Muschietti L,Ferraro G,Martino V,Acevedo C

    更新日期：2005-01-01 00:00:00

  • Anti-inflammatory lignanamides from the roots of Solanum melongena L.

    abstract：:Four new lignanamides, melongenamides A-D (1-4), together with six known ones (5-10), were isolated from the roots of Solanum melongena L. Their structures were elucidated on the basis of 1D and 2D NMR experiments and by comparison of their spectroscopic and physical data with the literature values. Compounds 2-8 exhi...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2014.07.012

    authors： Sun J,Gu YF,Su XQ,Li MM,Huo HX,Zhang J,Zeng KW,Zhang Q,Zhao YF,Li J,Tu PF

    更新日期：2014-10-01 00:00:00

  • Lathyrane diterpenes from Euphorbia prolifera and their inhibitory activities on LPS-induced NO production.

    abstract：:A new lathyrane diterpene (1), an unreported spectroscopic data lathyrane diterpenene (2), and two known analaogues (3 and 4) have been isolated from Euphorbia prolifera. Their structures were elucidated as (12E,2S,3S,4R,5R,6S,9S,11S,15R)-3-butyryloxy-5,15-diacetoxy-6,17-epoxylathyra- 12-en-14-one (1), (12E,2S,3S,4R,5...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2012.06.014

    authors： Xu J,Jin DQ,Song H,Guo Y,He Y

    更新日期：2012-10-01 00:00:00

  • New isocoumarins and alkaloid from Chinese insect medicine, Eupolyphaga sinensis Walker.

    abstract：:Two new isocoumarins (1 and 2), a new alkaloid (3), and a known N-acetyldopamine dimer (4) were isolated from the ethyl acetate extract of Chinese insect medicine Eupolyphaga sinensis. Their structures were elucidated on the basis of detailed spectroscopic investigations, such as 1D- and 2D NMR spectroscopy, as well a...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2012.06.005

    authors： Jiang HL,Luo XH,Wang XZ,Yang JL,Yao XJ,Crews P,Valeriote FA,Wu QX

    更新日期：2012-10-01 00:00:00

  • Antibacterial and antifungal activities of Euroschinus papuanus.

    abstract：:The crude methanolic extracts of the leaves, stem bark, stem heart wood, root bark and root heart wood of Euroschinus papuanus and the fractions obtained on partitioning with petrol, dichloromethane (D), ethyl acetate (E) and butanol (B), exhibited a broad spectrum antibacterial activity. Fractionation drastically enh...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2004.03.002

    authors： Khan MR,Omoloso AD,Kihara M

    更新日期：2004-06-01 00:00:00

  • Berberine hydrochloride attenuates cyclooxygenase-2 expression in rat small intestinal mucosa during acute endotoxemia.

    abstract：:The effect of berberine hydrochloride (BBR) on inducible cyclooxygenase-2 (COX-2) in small intestinal mucosa and related mechanisms was investigated in a rat model of acute endotoxemia. The results showed that lipopolysaccharide (LPS) increased COX-2 expression, whereas SB202190 and BBR curtailed it. LPS increased pho...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2011.05.013

    authors： Feng AW,Yu C,Mao Q,Li N,Li QR,Li JS

    更新日期：2011-10-01 00:00:00

  • Diterpenoids from the seeds of Euphorbia lathyris and their effects on microglial nitric oxide production.

    abstract：:Four new lathyrane-type diterpenoids (1-4) and a novel macrocyclic diterpenoid (5) featuring a 5/7/7/4-fused ring system, together with seventeen known ones (6-22), were isolated from the seeds of Euphorbia lathyris. Their structures were elucidated by extensive spectroscopic analyses and single crystal X-ray crystall...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2021.104834

    authors： Zuo Q,Mu HY,Gong Q,Ding X,Wang W,Zhang HY,Zhao WM

    更新日期：2021-01-26 00:00:00

  • Antidepressant-like effects of cajaninstilbene acid and its related mechanisms in mice.

    abstract：:Cajaninstilbene acid (CSA), a bioactive constituent isolated from pigeon pea leaves, exhibited neuroprotective activities in previous studies. The present study aims to evaluate the antidepressant effects of CSA by using behavioral despair models of tail suspension test (TST) and forced swimming test (FST), and a chro...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2019.104450

    authors： Zhang MD,Tao X,Pan RL,Wang LS,Li CC,Zhou YF,Liao YH,Chen SG,Chang Q,Liu XM

    更新日期：2020-03-01 00:00:00

  • Steroidal glycosides from Reineckia carnea.

    abstract：:Three new steroidal glycosides (1-3) and a novel natural product 4 firstly obtained from a plant source, together with two known steroidal glycosides (5-6) have been isolated from the whole plant of Reineckia carnea. Their structures were determined by physicochemical properties and spectroscopic methods, and their cy...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2015.07.008

    authors： Song X,Zhang D,He H,Li Y,Yang X,Deng C,Tang Z,Cui J,Yue Z

    更新日期：2015-09-01 00:00:00