Anti-inflammatory lignanamides from the roots of Solanum melongena L.

Abstract:

:Four new lignanamides, melongenamides A-D (1-4), together with six known ones (5-10), were isolated from the roots of Solanum melongena L. Their structures were elucidated on the basis of 1D and 2D NMR experiments and by comparison of their spectroscopic and physical data with the literature values. Compounds 2-8 exhibited inhibitions of nitric oxide production in lipopolysaccharide-induced RAW 264.7 macrophages with IC50 values ranging from 16.2 to 58.5 μM.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Sun J,Gu YF,Su XQ,Li MM,Huo HX,Zhang J,Zeng KW,Zhang Q,Zhao YF,Li J,Tu PF

doi

10.1016/j.fitote.2014.07.012

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

110-6

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(14)00192-0

journal_volume

98

pub_type

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