Abstract:
:A weak estrogenicity of puerarin on reproductive organs was addressed in female rats. In short-term treatment, immature ovariectomized rats were injected with 0.7 mg/kg BW/day of puerarin, for 14 days. Puerarin did not increase uterus weights, endometrium and myometrium areas, and the percent of cornified cells (%Co), but it increased the number of uterine glands. In long-term treatment, mature rats were injected with 7.0mg/kg BW/day of puerarin for 140 days. Puerarin did not increase uterus weights, endometrium and myometrium areas, and the number of uterine glands, but a significant increase in the %Co was observed from day 98 onwards.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Malaivijitnond S,Tungmunnithum D,Gittarasanee S,Kawin K,Limjunyawong Ndoi
10.1016/j.fitote.2010.01.019subject
Has Abstractpub_date
2010-09-01 00:00:00pages
569-76issue
6eissn
0367-326Xissn
1873-6971pii
S0367-326X(10)00036-5journal_volume
81pub_type
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