A postmenopause-like model of ovariectomized Wistar rats to identify active principles of Erythrina lysistemon (Fabaceae).

abstract：:A sensitive and specific HPLC method was developed to analyze baicalin in rat plasma. The author had compared the pharmacokinetics of baicalin after oral administration of HLJDT decoction or pure baicalin in MCAO and sham-operated rats. All the rats were divided into two groups, MCAO and sham-operated rats. Each group...

journal_title：Fitoterapia

authors： Zeng MF,Pan LM,Zhu HX,Zhang QC,Guo LW

更新日期：2010-09-01 00:00:00

abstract：:The objective of this study was to evaluate potential hepatoprotective capabilities of quercetin in relation to its modulation of the HO-1 and NOS-2 activities in an experimental model of fulminant liver failure. Liver insult was induced by in vivo administration of D-galactosamine (d-GalN, 400 mg/kg, i.p.) and lipopo...

journal_title：Fitoterapia

authors： Lekić N,Canová NK,Hořínek A,Farghali H

更新日期：2013-06-01 00:00:00

abstract：:alpha(2)beta(1) and alpha(IIb)beta(3) integrins, that support platelet adhesion to collagen and fibrinogen, respectively, share common signaling molecules. The effect of quercetin on platelet static adhesion to collagen and fibrinogen was assessed and correlated with its kinase inhibitory activity. Quercetin strongly ...

journal_title：Fitoterapia

authors： Navarro-Núñez L,Lozano ML,Martínez C,Vicente V,Rivera J

更新日期：2010-03-01 00:00:00

abstract：:The effects of the aqueous extract of the leaf of Euphrasia officinale on blood glucose levels in normal and alloxan-diabetic rats were investigated. The treatment of alloxan-induced diabetic rats brought down the raised glucose levels, while the extract was devoid of hypoglycemic effect in normal rats. ...

journal_title：Fitoterapia

authors： Porchezhian E,Ansari SH,Shreedharan NK

更新日期：2000-09-01 00:00:00

abstract：:Alkaloids comprise one of the largest groups of plant secondary metabolites including vinca alkaloids. The ability of six alkaloids from Veratrum lobelianum, one from Veratrum nigrum and three from Peganum nigellastrum to modify transport activity of MDR1 was studied. Flow-cytometry in a multidrug-resistant human MDR1...

journal_title：Fitoterapia

authors： Ivanova A,Serly J,Christov V,Stamboliyska B,Molnar J

更新日期：2011-06-01 00:00:00

abstract：:Ten coumarins were isolated from Peucedanum luxurians. The rare coumarins stenocarpin, stenocarpin isobutyrate, officinalin, officinalin isobutyrate, 8-methoxypeucedanin and the known xanthotoxin, isoimperatorin, bergaptene, peucedanin and cnidilin were isolated. All isolated compound were identified by means of spect...

journal_title：Fitoterapia

authors： Chinou I,Widelski J,Fokialakis N,Magiatis P,Glowniak K

更新日期：2007-09-01 00:00:00

abstract：:Natural products chemistry is the discipline that lies at the heart of modern pharmacognosy. The field encompasses qualitative and quantitative analytical tools that range from spectroscopy and spectrometry to chromatography. Among other things, modern research on crude botanicals is engaged in the discovery of the ph...

journal_title：Fitoterapia

authors： Betz JM,Brown PN,Roman MC

更新日期：2011-01-01 00:00:00

abstract：:Five rare sesquiterpene lactone dimers, vlasouliolides E-I, were isolated from Vladimiria souliei. Their chemical structures were elucidated by spectroscopic analysis. Furthermore, 2 and 4 were unambiguously confirmed by Cu-Kα X-ray crystallographic analysis. Compounds 1, 2, 4 and 5 exhibited significant anti-inflamma...

journal_title：Fitoterapia

authors： Wu ZL,Wang JX,Chen LP,Dong HY,Li HL,Zhang WD

更新日期：2018-03-01 00:00:00

abstract：:Six new monoterpenoid indole alkaloids, 19(E)-9-demethoxy-16-dehydroxylchitosenine-17-O- β-d-glucopyranoside (1), 19(E)-9,10-didemethoxy-16-dehydroxylchitosenine-17-O-β-d-gluco-pyranoside (2), 19(E)-9,10-didemethoxy-16-dehydroxyl-11-methoxychitosenine (3), 19(E)-9,10-didemethoxy-16-dehydroxyl-11-methoxychitosenine-17-...

journal_title：Fitoterapia

authors： Yang WX,Chen YF,Yang J,Huang T,Wu LL,Xiao N,Hao XJ,Zhang YH

更新日期：2018-01-01 00:00:00

abstract：:Diketopiperazine is a natural products found from bacteria, fungi, marine sponges, gorgonian and red algae. They are cyclic dipeptides possessing relatively simple and rigid structures with chiral nature and various side chains. The compounds in this structure class have been known to possess diverse bioactivities inc...

journal_title：Fitoterapia

authors： Lee W,Ku SK,Choi H,Bae JS

更新日期：2016-04-01 00:00:00

abstract：:A series of novel myricetin derivatives containing benzimidazole skeleton were constructed. The structure of compound 4g was further corroborated via X-ray single crystal diffractometer. The antimicrobial bioassays showed that all compounds exhibited potent inhibitory activities against Xanthomonas axonopodis pv. Citr...

journal_title：Fitoterapia

authors： Chen M,Tang X,Liu T,Peng F,Zhou Q,Luo H,He M,Xue W

更新日期：2020-12-11 00:00:00

abstract：:Four pairs of racemic phenylpropanoids (1a/1b-4a/4b), including five new compounds (1a/1b, 2a, 3a, and 4a) were obtained from the root barks of Ailanthus altissima (Mill.) Swingle. Their structures were determined by comprehensive spectroscopic analyses. The absolute configurations of the enantiomers were determined b...

journal_title：Fitoterapia

authors： Yan ZY,Chen JJ,Duan ZK,Yao GD,Lin B,Wang XB,Huang XX,Song SJ

更新日期：2018-10-01 00:00:00

abstract：:Acteoside, which belongs to the family of phenylethanoid glycosides (PhGs), has extensive biological activities, including strong antioxidant, anti-inflammatory, hepatoprotect, and cell apoptosis regulation. Like other PhGs compounds, the fate of acteoside in the gut for both parent polyphenols and their degradation p...

journal_title：Fitoterapia

authors： Su D,Li W,Xu Q,Liu Y,Song Y,Feng Y

更新日期：2016-07-01 00:00:00

abstract：:The effects of the essential oil of Eucalyptus tereticornis (EOET), especially the effects of its constituents alpha- and beta-pinene, were studied on rat trachea in vitro. In tracheal rings, EOET, alpha- or beta-pinene potentiated the contractions induced by acetylcholine (ACh). Contractions induced by K(+) (60mM) we...

journal_title：Fitoterapia

authors： Lima FJ,Brito TS,Freire WB,Costa RC,Linhares MI,Sousa FC,Lahlou S,Leal-Cardoso JH,Santos AA,Magalhães PJ

更新日期：2010-09-01 00:00:00

abstract：:The therapeutic uses and methods of administration of 70 plants in the traditional medicine of Sarrabus (south-east Sardinia, Italy) are documented. Among these species, some were not reported previously for Sardinia, while others turn out to have an original therapeutic use. ...

journal_title：Fitoterapia

authors： Palmese MT,Uncini Manganelli RE,Tomei PE

更新日期：2001-08-01 00:00:00

abstract：:Four new aristolochic acid derivatives aristchamic A (1), aristchamic B (2), aristochamic C (3a), aristchamic D (3b) and one new aristolactam aristolactam-CV (4), together with 10 known compounds (5-14), were isolated from the rhizomes of Aristolochia championii. Their structures were assigned by detailed analysis of ...

journal_title：Fitoterapia

authors： Wang X,Shi GR,Liu YF,Li L,Chen RY,Yu DQ

更新日期：2017-04-01 00:00:00

abstract：:Smyrnium olusatrum (Apiaceae), well known as wild celery, is a biennal celery-scented plant used for many centuries as a vegetable, then abandoned after the introduction of celery. In the present work, the essential oil obtained from inflorescences and the amounts of its main constituents isofuranodiene, curzerene and...

journal_title：Fitoterapia

authors： Quassinti L,Maggi F,Barboni L,Ricciutelli M,Cortese M,Papa F,Garulli C,Kalogris C,Vittori S,Bramucci M

更新日期：2014-09-01 00:00:00

abstract：:Four new C18-diterpenoid alkaloids, weisaconitines A-D (1-4), were isolated from Aconitum weixiense. Based on extensive UV, IR, MS, 1D and 2D NMR analyses, their structures were elucidated as 8-O-ethyldolaconine (1), 4-demethylgenicunine B (2), 14-oxoaconosine (3), and 8-O-ethylaconosine (4). The analgesic activity of...

journal_title：Fitoterapia

authors： Zhao DK,Ai HL,Zi SH,Zhang LM,Yang SC,Guo HC,Shen Y,Chen YP,Chen JJ

更新日期：2013-12-01 00:00:00

abstract：:Aloe vera gel is a familiar ingredient in a range of widely available and advertisement healthcare and cosmetic products. As to date there are no documented reports on the standardization of A. vera gel and the following study is an attempt in this direction. A. vera gel was evaluated for its aloeverose content for th...

journal_title：Fitoterapia

authors： Lobo R,Prabhu KS,Shirwaikar A,Ballal M,Balachandran C,Shirwaikar A

更新日期：2010-06-01 00:00:00

abstract：:Calcium-activated chloride channels (CaCCs) as a kind of widely expressed ion channels play crucial roles in a variety of physiological regulation. TMEM16A has been identified as the molecular basis of CaCCs in numerous cell types and is considered a new drug target for many diseases. Regulating the function of TMEM16...

journal_title：Fitoterapia

authors： Zhu X,Zhang W,Jin L,Zhang G,Yang H,Yu B

更新日期：2020-11-01 00:00:00

abstract：:As a part of our ongoing search for plant-derived compounds that inhibit nitric oxide production, the methanol extract of the roots of Vladimiria souliei was found to show significant inhibitory effects on INF-γ-induced nitric oxide production in murine macrophage RAW264.7 cells. Bioactivity-guided isolation of the ex...

journal_title：Fitoterapia

authors： Xu J,Jin D,Shi D,Ma Y,Yang B,Zhao P,Guo Y

更新日期：2011-04-01 00:00:00

abstract：:Nineteen secolignans (1-19), including five new ones (1-5), were isolated from the whole plant of Peperomia dindygulensis. Their structures including stereochemistry were determined by spectroscopic methods, in particular NMR and electronic CD (ECD) analysis. All the isolates were evaluated for their inhibitory activi...

journal_title：Fitoterapia

authors： Sun RF,Zhu CC,Yang Y,Yu NJ

更新日期：2017-10-01 00:00:00

abstract：:Salvianolic acid B (Sal B) is the most abundant phenolic compound in Salvia miltiorrhiza, which has been widely used for the treatment of cardiovascular diseases in Oriental medicine. To elucidate structure of the converted compounds of Sal B by decoction in aqueous solution, Sal B (200 mg) was decocted in an aqueous ...

journal_title：Fitoterapia

authors： Lee HJ,Cho JY,Moon JH

更新日期：2012-10-01 00:00:00

abstract：:A fast and efficient method for the isolation of the C-glucosidated xanthones mangiferin and isomangiferin from the South-African plant Cyclopia genistoides was developed for the first time. The procedure involved extraction, liquid-liquid partitioning with ethyl acetate and subsequent precipitation of mangiferin and ...

journal_title：Fitoterapia

authors： Kokotkiewicz A,Luczkiewicz M,Pawlowska J,Luczkiewicz P,Sowinski P,Witkowski J,Bryl E,Bucinski A

更新日期：2013-10-01 00:00:00

abstract：:Four new sesquiterpene lactones, named artemargyinolides A-D (1-4), and seven known sesquiterpenoids (5-11) were isolated from Artemisia argyi. Their structures were elucidated based on the extensive analysis of spectroscopic data. The absolute configuration of 1 was assigned by X-ray crystallographic analysis. Compou...

journal_title：Fitoterapia

authors： Zhang LB,Lv JL

更新日期：2019-11-01 00:00:00

abstract：:A new cyclopeptide, pulvpeptin A (1), two pairs of norlignan lignanosides, tamariscinosides G and H (2, 3), together with five known compounds (4-8) were isolated from Selaginella pulvinata. The structures were elucidated by spectroscopic data and chemical degradation. The activity of tamariscinoside G (2) was evaluat...

journal_title：Fitoterapia

authors： Lv H,Li Y,Zhu M,Luo M,Qi J,Yu Z,Zhang H,Guo Y,Tong S,Li H,Yan J

更新日期：2020-06-01 00:00:00

abstract：:Chemical and biocatalytic synthesis of seven previously undescribed marchantin A ester derivatives has been presented. Chemical synthesis afforded three peresterified bisbibenzyl products (TE1-TE3), while enzymatic method, using lipase, produced regioselective monoester derivatives (ME1-ME4). The antiproliferative act...

journal_title：Fitoterapia

authors： Novakovic M,Simić S,Koračak L,Zlatović M,Ilic-Tomic T,Asakawa Y,Nikodinovic-Runic J,Opsenica I

更新日期：2020-04-01 00:00:00

abstract：:Chemical investigation of the cultured polyspore-derived mycobionts of a Pseudopyrenula subnudata lichen led to the isolation of two new compounds, subnudatones A and B (1 and 2), together with four known compounds, 1-(2-hydroxy-1,2,6-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)ethanone (3), libertalide C (4)...

journal_title：Fitoterapia

authors： Duong TH,Nguyen HH,Le TT,Tran TN,Sichaem J,Nguyen TT,Nguyen TP,Mai DT,Nguyen HH,Le HD

更新日期：2020-04-01 00:00:00

abstract：:In a two-microelectrode voltage clamp assay with Xenopus laevis oocytes, a petroleum ether extract (100 μg/mL) of the resin of Boswellia thurifera (Burseraceae) potentiated GABA-induced chloride currents (IGABA) through receptors of the subtype α₁β₂γ₂s by 319.8% ± 79.8%. With the aid of HPLC-based activity profiling, ...

journal_title：Fitoterapia

authors： Rueda DC,Raith M,De Mieri M,Schöffmann A,Hering S,Hamburger M

更新日期：2014-12-01 00:00:00

abstract：:One alkyl glycoside, saussurostelloside A (1), two phenolic glycosides, saussurostellosides B1 (2) and B2 (3), and 27 known compounds, including eleven flavonoids, seven phenolics, six lignans, one neolignan, one phenethyl glucoside and one fatty acid, were isolated from an ethanol extract of Saussurea stella (Asterac...

journal_title：Fitoterapia

authors： Wang TM,Wang RF,Chen HB,Shang MY,Cai SQ

更新日期：2013-07-01 00:00:00