Abstract：
:Oil production from the seeds of Camellia oleifera Abel. causes a great waste of shells which contain a lot of bioactive components. The aim of this research was to isolate flavonoid from the shells of C. oleifera Abel. and evaluate its uses. The shells were extracted by 70% methanol, hydrolyzed by 2M hydrochloric acid, and further crystallized in acetone, the corresponding yield of flavonoid was up to 2.1% (purity: 93.8%). The procedure is concise, quick and proper for industrial utilization of the shells. Flavonoid was identified as bimolecular kaempferol structure by UV, MS, (1)H NMR and (13)C NMR spectra, which is a new biflavonoid and first found in C. oleifera Abel. It showed stronger scavenging activity of DPPH and ABTS radicals than kaempferol. MDA decreased, and SOD and GSH-Px activities increased significantly in serum (P<0.01) and brain tissue (P<0.05) of mice after intragastric administration of biflavonoid at 200mg/kg/d for 30d. Its effects in vivo are superior to vitamin C and similar to kaempferol. Thus biflavonoid can be used as a prospective antioxidant to protect brain cells against damage from free radicals.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Ye Y,Guo Y,Luo YT,Wang YFdoi
10.1016/j.fitote.2012.09.006subject
Has Abstractpub_date
2012-12-01 00:00:00pages
1585-9issue
8eissn
0367-326Xissn
1873-6971pii
S0367-326X(12)00253-5journal_volume
83pub_type
杂志文章相关文献
FITOTERAPIA文献大全abstract：:Four new lignanamides, melongenamides A-D (1-4), together with six known ones (5-10), were isolated from the roots of Solanum melongena L. Their structures were elucidated on the basis of 1D and 2D NMR experiments and by comparison of their spectroscopic and physical data with the literature values. Compounds 2-8 exhi...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2014.07.012
更新日期：2014-10-01 00:00:00
abstract：:The antifungal activity of methanolic extract and alkaloidal fraction of Berberis aetnensis against Candida species was investigated. The crude extract was active against Candida species, this activity being higher than that of the alkaloidal fraction and berberine. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2006.10.007
更新日期：2007-02-01 00:00:00
abstract：:Three new secoiridoid aglycones of (-)-swermusic acid A (1) and B (3), and (-)-swerimuslatone A (2), and four new secoiridoid glycosides of 6'-O-formylsweroside (4), 6'-O-formylgentiopicroside (5), 6'-O-acetylamarogentin (6) and 6'-O-acetylamaronitidin (7), along with 40 known compounds (8-47) were isolated from Swert...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2015.01.020
更新日期：2015-04-01 00:00:00
abstract：:Phytochemical study on rhizomes of Beesia calthifolia resulted in the isolation of five new (1-5) and three known (6-8) cycloartane triterpenoids possessing a hemiketal or ketal group at C-24 from the EtOAc fraction of 95% ethanol extract. Their structures were determined by spectroscopic and chemical methods, especia...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2015.04.017
更新日期：2015-06-01 00:00:00
abstract：:The plant derived camptothecin (CPT) is a pentacyclic pyrroloquinoline alkaloid with unique antitumor activity. Successive discoveries of new CPT-producing plants occurred in recent years due to market demands. The scattered distribution among angiosperms drew researchers' attention. The aim of this review is to appra...
journal_title：Fitoterapia
pub_type： 杂志文章,评审
doi：10.1016/j.fitote.2019.02.014
更新日期：2019-04-01 00:00:00
abstract：:Successive petroleum ether, dichloromethane and methanol extracts of Ajuga remota aerial parts were tested in vitro for their antifungal activity. The petroleum ether fraction was found to be the most effective against the tested pathogens. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(00)00280-x
更新日期：2001-02-01 00:00:00
abstract：:The pharmacological active genus Thymus L. comprises over 200 species. Besides its traditional pharmacological use, thyme may reduce the risk of caries disease, however, there is very little respective literature. The pharmacological effects can be attributed to the secondary plant metabolites. The composition of the ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2017.07.005
更新日期：2017-09-01 00:00:00
abstract：:Bergenin, a major constituent of Caesalpinia digyna Rottler (Leguminosae) was isolated from its roots and was characterized by comparing its melting point and spectroscopic data (IR, (1)H, (13)C, Mass Spectra) with standard bergenin. Isolated bergenin was then evaluated for antidiabetic (Type 2) activity in streptozot...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2011.12.008
更新日期：2012-03-01 00:00:00
abstract：:One new Euphane-type triterpenoid 3β-hydroxytirucalla-5, 24-dien-21-oic acid (1), and ten known compounds (2-11) were isolated from Melia azedarach L. through bioassay-guided chemical analysis. The structures of the isolated compounds were established by means of 1D and 2D NMR spectroscopic ((1)H, (13)C, DEPT, COSY, H...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2014.07.014
更新日期：2014-10-01 00:00:00
abstract：:Although the bioactive compounds in goji have been thoroughly identified and quantified, little information is available on the bitter compounds in the berries, and no systematic works on the substances responsible for their bitterness have been performed. Herein, the substances contributing to the bitterness of berri...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2020.104543
更新日期：2020-06-01 00:00:00
abstract：:Tunicyclin L (1), cyclo (L-Pro1-Gly-L-Phe1-L-Ile-L-Pro2-L-Phe2 -L-Thr-L-Val), and 11 known compounds, including one cyclic peptide (2), eight carboline alkaloids (3 -10), one lignan (11) and one flavone (12) were isolated from the roots of Psammosilene tunicoides. Their structures were elucidated on the basis of exten...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2020.104628
更新日期：2020-09-01 00:00:00
abstract：:Five rare sesquiterpene lactone dimers, vlasouliolides E-I, were isolated from Vladimiria souliei. Their chemical structures were elucidated by spectroscopic analysis. Furthermore, 2 and 4 were unambiguously confirmed by Cu-Kα X-ray crystallographic analysis. Compounds 1, 2, 4 and 5 exhibited significant anti-inflamma...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2018.01.002
更新日期：2018-03-01 00:00:00
abstract：:The antioxidant effect of aqueous methanolic herb extracts of Serratula coronata, S. wolffii and S. tinctoria was investigated using both enzyme-dependent and enzyme-independent systems. The extracts displayed concentration-dependent inhibition of lipid peroxidation. Flavonoids and ecdysteroids present in the extracts...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2003.12.009
更新日期：2004-03-01 00:00:00
abstract：:More attention was paid to the anti-tumor activity of Rhizoma Paridis (RP) recently, of which the wild resource was decreased significantly. This study was aimed to elucidate the chemical characteristics of Paris fargesii var. brevipetala (PFB) that may be administrated as alternate resource of legal RP. A HPLC-ELSD m...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2012.01.003
更新日期：2012-06-01 00:00:00
abstract：:Seven compounds were isolated from the roots of Eurycoma longifolia, and characterized by comprehensive analysis of 1D and 2D NMR experiments along with single crystal X-ray diffraction. Among them, four new quassinoids were identified and three of them were diastereomers for each other. Compounds 1-7 were evaluated f...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.10.009
更新日期：2014-01-01 00:00:00
abstract：:A sensitive and specific HPLC method was developed to analyze baicalin in rat plasma. The author had compared the pharmacokinetics of baicalin after oral administration of HLJDT decoction or pure baicalin in MCAO and sham-operated rats. All the rats were divided into two groups, MCAO and sham-operated rats. Each group...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2010.01.004
更新日期：2010-09-01 00:00:00
abstract：:Goniothalamus macrophyllus (Blume) Hook. f. & Thoms. is a plant widely distributed in Malaysia. The aim of this study is to identify compounds from the roots of G. macrophyllus. The ground roots were extracted with aqueous methanol and partitioned sequentially with n-hexane, chloroform and butanol. Purification from t...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.03.028
更新日期：2013-07-01 00:00:00
abstract：:Two spiro paclitaxel-mimics consisting only of an oxetane D-ring and a C-13 side chain were designed and synthesized on the basis of analysis of structure-activity relationships (SAR) of paclitaxel. In vitro microtubule-stabilizing and antiproliferative assays indicated a moderate weaker activity of the mimics than pa...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.10.015
更新日期：2014-01-01 00:00:00
abstract：:A new flavone, 4'-hydroxy-6,7-methylenedioxy-3-methoxyflavone 1, and two other nucleosides, ribavirin 2 and adenosine 3, were isolated from the leaves of Dulacia egleri. The nucleosides were identified by spectroscopic techniques (1D, 2D-NMR) while the structure of the flavonoid was established by 1D, 2D-NMR analysis,...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2018.08.005
更新日期：2019-01-01 00:00:00
abstract：:A screening was conducted with 26 plants collected in the Brazilian southeast region, to identify plant extracts with antibacterial properties against Aeromonas hydrophila, Bacillus subtilis, Pseudomonas aeruginosa and Staphylococcus aureus. Initially, the agar diffusion method was employed. Then, those extracts prese...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2006.09.027
更新日期：2007-02-01 00:00:00
abstract：:Three new phloroglucinols, baeckenones D-F (1-3), were obtained from the leaves of Indonesian Baeckea frutescens, along with the known unusual endoperoxide, phloroglucinol (4). The structures of the isolated compounds were elucidated by 1D and 2D NMR and HREIMS spectra. Furthermore, the stereochemistry of baeckenone D...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2016.01.013
更新日期：2016-03-01 00:00:00
abstract：:A new cyclopeptide, pulvpeptin A (1), two pairs of norlignan lignanosides, tamariscinosides G and H (2, 3), together with five known compounds (4-8) were isolated from Selaginella pulvinata. The structures were elucidated by spectroscopic data and chemical degradation. The activity of tamariscinoside G (2) was evaluat...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2020.104562
更新日期：2020-06-01 00:00:00
abstract：:Malaria is one of the most devastating infectious diseases in the developing world. Until now, only one candidate malaria vaccine RTS,S/AS01 has shown modest protection in phase 3 trial in African infants. Hence the treatment of malaria still depends on the current chemotherapeutic drugs. Considering the resistance of...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2014.01.017
更新日期：2014-04-01 00:00:00
abstract：:The methanol extracts of Clematis papuasica leaves and stem bark and of Nauclea obversifolia leaves, stem and root barks showed awide spectrum of antibacterial activity which was increased on fractionation (petrol, dichloromethane, ethyl acetate), the ethyl acetate fractions being in all cases the most effective. None...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(01)00258-1
更新日期：2001-06-01 00:00:00
abstract：:Beyond its role in the activation of protein C, the endothelial cell protein C receptor (EPCR) plays an important role in the cytoprotective pathway. EPCR can be shed from the cell surface, which is mediated by tumor necrosis factor-α converting enzyme (TACE). Polyozellin, a major constituent of a Korea edible mushroo...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2015.11.005
更新日期：2016-01-01 00:00:00
abstract：:Investigation of the dichloromethane extract of the stem of Filicium decipiens yielded a new natural product, 24-norneohopa-4(23),22(29)-diene-3beta,6beta,7beta-triol 7-caffeate (1). ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(01)00296-9
更新日期：2001-11-01 00:00:00
abstract：:Five new sesquiterpenes (1-5) along with ten known ones were isolated from the heartwood of Dalbergia odorifrea T. Chen. Their structures were determined by spectroscopic techniques including MS, UV, IR, 1D and 2D NMR. Bioassay results showed that compounds 1 and 9 had inhibitory effect on Candida albicans, and compou...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2014.02.013
更新日期：2014-06-01 00:00:00
abstract：:In a two-microelectrode voltage clamp assay with Xenopus laevis oocytes, a petroleum ether extract (100 μg/mL) of the resin of Boswellia thurifera (Burseraceae) potentiated GABA-induced chloride currents (IGABA) through receptors of the subtype α₁β₂γ₂s by 319.8% ± 79.8%. With the aid of HPLC-based activity profiling, ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2014.09.002
更新日期：2014-12-01 00:00:00
abstract：:StAPs are potato aspartic proteases with cytotoxic activity against plant pathogens and spermatozoa. StAPs cytotoxic activity is selective, since these proteins do not exert toxic effect on plant cells and erythrocytes. In this work, we investigated the capacity of StAPs to exert cytotoxicity on human leukaemia cells....
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2009.10.004
更新日期：2010-07-01 00:00:00
abstract：:Thirty-five crude extracts from 11 Panamanian plants, distributed in 10 genera and five families, were evaluated for their in vitro cytotoxicity. Four extracts exhibited an inhibition of cellular growth at IC(50) values lower than 25 microg/ml which was considered a significant activity. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(03)00052-2
更新日期：2003-06-01 00:00:00
