A cyclic peptide and two pairs of norlignan lignanoside epimers from Selaginella pulvinata.

abstract：:Zuojinwan, which consists of Rhizoma coptidis-Evodia rutaecarpa powder (6:1,g/g), is a traditional Chinese medicine (TCM) prescription, clinically used for the treatment of gastro-intestinal disorders. This study compared the pharmacokinetics of dehydroevodiamine and coptisine, the main active ingredients in Zuojinwan...

journal_title：Fitoterapia

authors： Yan R,Wang Y,Shen W,Liu Y,Di X

更新日期：2011-12-01 00:00:00

abstract：:Investigation of the bioactive secondary metabolites of the marine actinomycetes Rubrobacter radiotolerans led to the isolation and characterization of two naturally rare dimeric indole derivatives (1 and 2). The structures of these new compounds were elucidated by spectroscopic data interpretation, and the absolute c...

journal_title：Fitoterapia

authors： Li JL,Huang L,Liu J,Song Y,Gao J,Jung JH,Liu Y,Chen G

更新日期：2015-04-01 00:00:00

abstract：:Four new sesquiterpenes (1-2, 6-7), a new pyranone glycoside (10) along with six known compounds, were isolated from the whole plant of Erigeron breviscapus. Their planar structures were elucidated using extensive spectroscopic analyses. Brevisterpene A (1) and brevisterpene B (2) were proved to be a pair of diastereo...

journal_title：Fitoterapia

authors： Han S,Liu Y,Hou Z,Sun X,Yao G,Gao P,Li L,Song S

更新日期：2019-10-01 00:00:00

abstract：:Four new C18-diterpenoid alkaloids, weisaconitines A-D (1-4), were isolated from Aconitum weixiense. Based on extensive UV, IR, MS, 1D and 2D NMR analyses, their structures were elucidated as 8-O-ethyldolaconine (1), 4-demethylgenicunine B (2), 14-oxoaconosine (3), and 8-O-ethylaconosine (4). The analgesic activity of...

journal_title：Fitoterapia

authors： Zhao DK,Ai HL,Zi SH,Zhang LM,Yang SC,Guo HC,Shen Y,Chen YP,Chen JJ

更新日期：2013-12-01 00:00:00

abstract：:One new phenanthrene, aphyllone A (1) and four new bibenzyl derivatives, aphyllone B (2) and aphyllals C-D (3-5), together with nine known compounds (6-14), were isolated from the stems of Dendrobium aphyllum (Roxb.) C. E. Fischer. The structures of these new compounds were elucidated by means of extensive spectroscop...

journal_title：Fitoterapia

authors： Yang D,Liu LY,Cheng ZQ,Xu FQ,Fan WW,Zi CT,Dong FW,Zhou J,Ding ZT,Hu JM

更新日期：2015-01-01 00:00:00

abstract：:Investigators and sponsors of dietary supplement research need to know the relevant regulatory requirements and how to comply with them. This brief review describes how research on dietary supplements is regulated by FDA. In general, whether an FDA sanctioned Investigational New Drug (IND) application is required for ...

journal_title：Fitoterapia

authors： Chen ST

更新日期：2011-01-01 00:00:00

abstract：:Three undescribed polycyclic polyprenylated acylphloroglucinols (PPAPs) and three tocotrienols derivatives, named as paucinochymol A-F (1-3 and 10-12), together with six known PPAPs, were isolated from the fruits of Garcinia paucinervis. Their structures and absolute configurations were determined by extensive NMR ana...

journal_title：Fitoterapia

authors： Tan X,Zhong F,Teng H,Li Q,Li Y,Mei Z,Chen Y,Yang G

更新日期：2020-10-01 00:00:00

abstract：:Three new secoiridoids, swermacrolactones A-C (1-3), together with fourteen known compounds were isolated from Swertia macrosperma. Their structures were elucidated based on extensive spectroscopic analyses (IR, UV, MS, 1D and 2D NMR). By anti-HBV assay on the Hep G 2.2.15 cell line in vitro, the most active compound,...

journal_title：Fitoterapia

authors： Wang HL,Geng CA,Ma YB,Zhang XM,Chen JJ

更新日期：2013-09-01 00:00:00

abstract：:Phytochemical investigations on Physalis. alkekengi L. var. franchetii, a widespread traditional Chinese medicine, led to the isolation and identification of three new sesquiterpenoids physalisitins A-C (1-3). Their structures were elucidated by NMR and HRESIMS analysis, and their absolute configurations were determin...

journal_title：Fitoterapia

authors： Zhang JL,Zhou FF,Li YZ,Feng T,Jiang LL,Jiang RW,Zhang XX,Li XD

更新日期：2020-03-01 00:00:00

abstract：:Effects of protopanaxdiol (PDG) and protopanaxatriol (PTG) types of ginsenosides isolated from the leaves of American ginseng on porcine pancreatic lipase activity were determined in vitro. PDG inhibited the pancreatic lipase activity in a dose-dependent manner at the concentrations of 0.25-1mg/ml. It inhibited hydrol...

journal_title：Fitoterapia

authors： Liu R,Zhang J,Liu W,Kimura Y,Zheng Y

更新日期：2010-12-01 00:00:00

abstract：:Phytochemical studies on the ethanol extract of the aerial parts of Ecdysanthera rosea led to the isolation of three new compounds, hydroquinone diglycoside acyl esters, ecdysanrosin A (1) and sesquiterpene, 5β-hydroperoxycostic acid (2) and apocarotenoid, 2, 4, 7-trimethyl-2, 4, 6, 8-tetraene-dialdehyde (3). Their st...

journal_title：Fitoterapia

authors： Zhu X,Zhang Q,Kong L,Wang F,Luo S

更新日期：2010-10-01 00:00:00

abstract：:Two new steroidal esters with an unusual framework, Sinkiangenorin A and B, a new organic acid glycoside, Sinkiangenorin C, and four known lignin compounds were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds were established by spectroscopic analysis and single-crystal X-ray diffrac...

journal_title：Fitoterapia

authors： Li G,Li X,Cao L,Shen L,Zhu J,Zhang J,Wang J,Zhang L,Si J

更新日期：2014-09-01 00:00:00

abstract：:6,7-Dimethylesculetin (D), geniposide (G) and rhein (R) are the three major active ingredients of Yin-Chen-Hao-Tang (YCHT), a famous Chinese herbal formula, which has been shown to be clinically effective for treating hepatic injury (HI) syndrome. The present study was conducted to investigate the therapeutic and syne...

journal_title：Fitoterapia

authors： Zhang A,Sun H,Yuan Y,Sun W,Jiao G,Wang X

更新日期：2011-12-01 00:00:00

abstract：:Infusions of Picrolemma sprucei roots, stems and leaves are used in traditional medicine throughout the Amazon region from the Guianas to Brazil and Peru in the treatment of gastritis, intestinal helminths and malaria. As there are no studies describing its mode of action in providing a gastroprotective effect, we det...

journal_title：Fitoterapia

authors： Vieira SM,Silva RL,Lemos HP,Amorim RC,Silva EC,Reinach PS,Cunha FQ,Pohlit AM,Cunha TM

更新日期：2014-06-01 00:00:00

abstract：:The isolation of cinchonicine-derived alkaloids epicinchonicinol (1), cinchonidicinol (2) and a mixture of dihydrocinchonicinol and dihydrocinchonidicinol (3) from the dried bark of Ladenbergia oblongifolia, is reported along with (1)H and (13)C-NMR data. ...

journal_title：Fitoterapia

authors： Okunade AL,Lewis WH,Elvin-Lewis MP,Casper SJ,Goldberg DE

更新日期：2001-08-01 00:00:00

abstract：:Glabridin, a prenylated isoflavonoid of G. glabra L. roots (European licorice, Fabaceae), has been associated with a wide range of biological properties such as antioxidant, anti-inflammatory, anti-atherogenic, regulation of energy metabolism, estrogenic, neuroprotective, anti-osteoporotic, and skin-whitening. While g...

journal_title：Fitoterapia

authors： Simmler C,Pauli GF,Chen SN

更新日期：2013-10-01 00:00:00

abstract：:Six new flavonoids, seladoeflavones A-F (1-6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroi...

journal_title：Fitoterapia

authors： Zou Z,Xu K,Xu P,Li X,Cheng F,Li J,Yu X,Cao D,Li D,Zeng W,Zhang G,Tan G

更新日期：2017-01-01 00:00:00

abstract：:Natural products chemistry is the discipline that lies at the heart of modern pharmacognosy. The field encompasses qualitative and quantitative analytical tools that range from spectroscopy and spectrometry to chromatography. Among other things, modern research on crude botanicals is engaged in the discovery of the ph...

journal_title：Fitoterapia

authors： Betz JM,Brown PN,Roman MC

更新日期：2011-01-01 00:00:00

abstract：:This review reports the last decade acquisitions on grapefruit. New coumarins and limonoids were isolated and characterised. The bioavailability of many drugs was tested with grapefruit juice (GJ) coadministration; the inhibition on cytochrome P450 seems due to a synergic action between flavonoids and coumarins. Antim...

journal_title：Fitoterapia

authors： Tirillini B

更新日期：2000-08-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is highly prevalent among global populations, with an estimated number of infected patients being 170 million. Approximately 70-80% of patients acutely infected with HCV will progress to chronic liver disease, such as liver cirrhosis and hepatocellular carcinoma, which is a substantia...

journal_title：Fitoterapia

authors： Wahyuni TS,Widyawaruyanti A,Lusida MI,Fuad A,Soetjipto,Fuchino H,Kawahara N,Hayashi Y,Aoki C,Hotta H

更新日期：2014-12-01 00:00:00

abstract：:Four new triterpenoids, sweriyunnangenin A (1), sweriyunnanosides A (2), B (3) and C (4), along with nineteen known compounds (5-23) were isolated from Swertia yunnanensis. Based on extensive spectroscopic analyses (1D- and 2D-NMR, HRESIMS, UV, IR, [α]D), the structures of sweriyunnangenin A (1), sweriyunnanosides A (...

journal_title：Fitoterapia

authors： Cao TW,Geng CA,Jiang FQ,Ma YB,He K,Zhou NJ,Zhang XM,Zhou J,Chen JJ

更新日期：2013-09-01 00:00:00

abstract：:Seventy-six plant species from 46 botanical families, traditionally used to treat intestinal diseases in Mbalmayo region are recorded. The local names and the way the plants are used are indicated. ...

journal_title：Fitoterapia

authors： Noumi E,Yomi A

更新日期：2001-03-01 00:00:00

abstract：:Glucocorticoids (GCs) are usually used to treat inflammatory diseases. However, they cause severe and irreversible side effects, which limit the use of these compounds. Ginsenoside Rg1 had been demonstrated to possess anti-inflammatory and anti-cancer effects. The present study was designed to investigate whether Rg1 ...

journal_title：Fitoterapia

authors： Song Y,Zhao F,Zhang L,Du Y,Wang T,Fu F

更新日期：2013-12-01 00:00:00

abstract：:Diterpene alkaloids neoline (1), napelline (2), isotalatizidine (3), karakoline (4), senbusine A (5), senbusine C (6), aconitine (7) and taurenine (8) were identified from Aconitum napellus L. subsp. firmum, four (2-4, 6) of which are reported for the first time from this plant. The structures were determined by means...

journal_title：Fitoterapia

authors： Kiss T,Orvos P,Bánsághi S,Forgo P,Jedlinszki N,Tálosi L,Hohmann J,Csupor D

更新日期：2013-10-01 00:00:00

abstract：:Cinnamon is the dried bark of Cinnamomum cassia Presl, and its main component is cinnamaldehyde (CA). Decades of synthetic pesticide use to control parasitic nematodes that can harm plants has seriously polluted the environment and poses a risk to soil ecology, highlighting the need to develop natural biological pesti...

journal_title：Fitoterapia

authors： Lu L,Shu C,Chen L,Yang Y,Ma S,Zhu K,Shi B

更新日期：2020-10-01 00:00:00

abstract：:Five new sesquiterpenoids, including two linderanes (1-2) and three eudesmanes (3-5) were isolated from the seeds of Sarcandra glabra. Their structures and relative configurations were established by spectroscopic data analysis. 1 was a rare linderane derivative having an 18-membered triester ring which is a common ch...

journal_title：Fitoterapia

authors： Yaermaimaiti S,Wang P,Luo J,Li RJ,Kong LY

更新日期：2016-06-01 00:00:00

abstract：:European Hawthorn species (Crataegus spp.) are traditionally used for their demonstrated cardioprotective benefits. Most products are based on the compendial leaf and flower drug (LFD), which is standardised on the total flavonoid content (TF). In order to reduce variability associated with the wild plant origin and t...

journal_title：Fitoterapia

authors： Peschel W,Bohr C,Plescher A

更新日期：2008-01-01 00:00:00

abstract：:A phytochemical fractionation of the methanol extract of the Morus alba leaves led to the isolation of eleven flavonoids (1-11). The structure of the new 3'-geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone (1) was elucidated by means of spectroscopic methods. The cytotoxicity of the isolated compounds against human cerv...

journal_title：Fitoterapia

authors： Dat NT,Binh PT,Quynh le TP,Van Minh C,Huong HT,Lee JJ

更新日期：2010-12-01 00:00:00

abstract：:Four new lathyrane-type diterpenoids (1-4) and a novel macrocyclic diterpenoid (5) featuring a 5/7/7/4-fused ring system, together with seventeen known ones (6-22), were isolated from the seeds of Euphorbia lathyris. Their structures were elucidated by extensive spectroscopic analyses and single crystal X-ray crystall...

journal_title：Fitoterapia

authors： Zuo Q,Mu HY,Gong Q,Ding X,Wang W,Zhang HY,Zhao WM

更新日期：2021-01-26 00:00:00

abstract：:Lanaroflavone (1), a biflavonoid isolated from the methanol extract of the aerial part of Campnosperma panamense by bioguided fractionation, has been assessed for in vitro antiprotozoal activity. Lanaroflavone showed both antimalarial and leishmanicidal activities, but was inactive against Chagas disease vector, Trypa...

journal_title：Fitoterapia

authors： Weniger B,Vonthron-Sénécheau C,Arango GJ,Kaiser M,Brun R,Anton R

更新日期：2004-12-01 00:00:00