Sesquiterpenoids from the seeds of Sarcandra glabra and the potential anti-inflammatory effects.

Abstract:

:Five new sesquiterpenoids, including two linderanes (1-2) and three eudesmanes (3-5) were isolated from the seeds of Sarcandra glabra. Their structures and relative configurations were established by spectroscopic data analysis. 1 was a rare linderane derivative having an 18-membered triester ring which is a common characteristic in linderane dimers. Compounds 1-5 were investigated for their inhibitory effects on NO production in LPS-induced macrophages and 1 showed moderate bioactivity.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Yaermaimaiti S,Wang P,Luo J,Li RJ,Kong LY

doi

10.1016/j.fitote.2016.03.020

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

7-11

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(16)30063-6

journal_volume

111

pub_type

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