Abstract:
:Five new sesquiterpenoids, including two linderanes (1-2) and three eudesmanes (3-5) were isolated from the seeds of Sarcandra glabra. Their structures and relative configurations were established by spectroscopic data analysis. 1 was a rare linderane derivative having an 18-membered triester ring which is a common characteristic in linderane dimers. Compounds 1-5 were investigated for their inhibitory effects on NO production in LPS-induced macrophages and 1 showed moderate bioactivity.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Yaermaimaiti S,Wang P,Luo J,Li RJ,Kong LYdoi
10.1016/j.fitote.2016.03.020subject
Has Abstractpub_date
2016-06-01 00:00:00pages
7-11eissn
0367-326Xissn
1873-6971pii
S0367-326X(16)30063-6journal_volume
111pub_type
杂志文章相关文献
FITOTERAPIA文献大全abstract::With the goal of unravelling antimicrobial agents and mixtures inspired by plant defences, we investigated the antibacterial and antifungal efficacy of Hirtellina lobelii DC. essential oil (EO), both alone and in combination with antimicrobial drugs. Hirtellina lobelii DC. EO was analysed by GC, GC-MS and partial frac...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2019.01.001
更新日期:2019-03-01 00:00:00
abstract::Commiphoins A-C (1-3), three new cadinane-type sesquiterpenes, together with two known cadinane-type sesquiterpenes (4 and 5) were isolated from the resinous exudates of Commiphora myrrha. Their structures and relative configurations were established on the basis of comprehensive spectroscopic methods, including HRESI...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2020.104536
更新日期:2020-04-01 00:00:00
abstract::Curcuphenol is a sesquiterpene isolated from sponges and plants having several significant biological activities. The present study explored its effect on cell proliferation and apoptosis in Caco-2 human colon cancer cells. It was demonstrated that curcuphenol in concentrations in the range of 29-116 µg/ml inhibited c...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2010.04.001
更新日期:2010-10-01 00:00:00
abstract::A weak estrogenicity of puerarin on reproductive organs was addressed in female rats. In short-term treatment, immature ovariectomized rats were injected with 0.7 mg/kg BW/day of puerarin, for 14 days. Puerarin did not increase uterus weights, endometrium and myometrium areas, and the percent of cornified cells (%Co),...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2010.01.019
更新日期:2010-09-01 00:00:00
abstract::A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to identify and quantify the camptothecin quaternary derivative CPT8 for application in pharmacokinetics and tissue distribution studies. Rat plasma and tissue samples were extracted with methanol by using camptothecin as the internal sta...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.06.012
更新日期:2013-10-01 00:00:00
abstract::Three new phenylpropanoid derivatives, dasymaroacid A (1), dasymaroesters B and C (2 and 3), and one new polyoxygenated 6H-dibenzo[b,d]pyran-6-one derivative dasymarolactone D (4), together with seven known compounds (5-11), were isolated from the stems of Dasymaschalon rostratum Merr. Compounds 1 and 2 are unusual ph...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2017.02.003
更新日期:2017-04-01 00:00:00
abstract::Five new lanostane triterpenoids, ganoderic acid XL1 (1), ganoderic acid XL2 (2), 20-hydroxy-ganoderic acid AM1 (3), ganoderenic acid AM1 (4) and ganoderesin C (5), together with five known triterpenoids (6-10) were isolated from the fruiting bodies of Ganoderma theaecolum. Chemical structures were elucidated on the b...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2014.08.004
更新日期:2014-10-01 00:00:00
abstract::The last few decades have seen an alarming rise in fungal infections, which currently represent a global health threat. Despite extensive research towards the development of new antifungal agents, only a limited number of antifungal drugs are available in the market. The routinely used polyene agents and many azole an...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2016.05.016
更新日期:2016-07-01 00:00:00
abstract::One new Euphane-type triterpenoid 3β-hydroxytirucalla-5, 24-dien-21-oic acid (1), and ten known compounds (2-11) were isolated from Melia azedarach L. through bioassay-guided chemical analysis. The structures of the isolated compounds were established by means of 1D and 2D NMR spectroscopic ((1)H, (13)C, DEPT, COSY, H...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2014.07.014
更新日期:2014-10-01 00:00:00
abstract::Two novel 2-arylbenzofuran dimers, shandougenines A (1) and B (2), and two new polyisoprenylated flavanones 3 (shandougenine C) and 4 (shandougenine D) were isolated from the 95% EtOH extract of Sophora tonkinensis, together with 18 known compounds. Their structures were determined on the basis of spectral data interp...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2014.08.019
更新日期:2014-12-01 00:00:00
abstract::The isolation of a new flavan, 5,7,4'-trihydroxy-8-ethoxycarbonylflavan (1), from the root of Daphne odora var. atrocaulis is reported. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2004.09.014
更新日期:2004-12-01 00:00:00
abstract::8,2'-Diprenylquercetin 3-methyl ether, a natural product with prominent anti-breast cancer activity, is the main active constituent of Sinopodophylli Fructus. A high-performance liquid chromatography with a diode array detector coupled with electrospray ionization ion trap time-of-flight multistage mass spectrometry (...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2019.104191
更新日期:2019-09-01 00:00:00
abstract::Chemical investigation of the n-butanol extract from the methanol extract of the root bark of Artocarpus nobilis furnished four new prenylated flavonoids together with artonin E 2'-methylether (4), isoartonin E 2'-methylether (5), dihydroisoartonin E 2'-methylether (6), artonin V 2'-methylether (7), artobiloxanthone (...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2007.07.014
更新日期:2008-01-01 00:00:00
abstract::Four new terpenoids, nemoralisins D-G (1-4), were isolated from the leaves and stems of Aphanamixis grandifolia, along with two known diterpenoids, nemoralisin C and nemoralisin. Among them, compound 1 is the first example of norsesquiterpenoid with δ-lactone moiety, and nemoralisins E-G (2-4), are a class of acyclic ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.10.014
更新日期:2014-01-01 00:00:00
abstract::The aerial parts of the endemic Australian plant Eremophila debilis (Myoporaceae) contain 3% dry weight of the biologically active 5,6,7,3',4',5'-hexamethoxyflavone, which had its structured confirmed using X-ray crystal crystallography. The presence of significant levels of the polypharmacologically active 5,6,7,3',4...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2017.07.014
更新日期:2018-04-01 00:00:00
abstract::Five rare sesquiterpene lactone dimers, vlasouliolides E-I, were isolated from Vladimiria souliei. Their chemical structures were elucidated by spectroscopic analysis. Furthermore, 2 and 4 were unambiguously confirmed by Cu-Kα X-ray crystallographic analysis. Compounds 1, 2, 4 and 5 exhibited significant anti-inflamma...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2018.01.002
更新日期:2018-03-01 00:00:00
abstract::The leaf essential oil of Filipendula vulgaris, consisting mainly of salicylaldehyde (68.6%), was screened for its antimicrobial activity by the disk diffusion and microdilution broth assays. The essential oil remarkably inhibited the growth of all of the tested bacteria and fungi. It seems that the antimicrobial natu...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2007.03.022
更新日期:2007-12-01 00:00:00
abstract::The present study was designed to verify whether frutalin (FTL) affords gastroprotection against the ethanol-induced gastric damage and to examine the underlying mechanism(s). Gastric damage was induced by intragastric administration of 0.2 ml of ethanol (96%). Mice in groups were pretreated with FTL (0.25, 0.5 and 1 ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.01.005
更新日期:2012-04-01 00:00:00
abstract::Diterpene alkaloids neoline (1), napelline (2), isotalatizidine (3), karakoline (4), senbusine A (5), senbusine C (6), aconitine (7) and taurenine (8) were identified from Aconitum napellus L. subsp. firmum, four (2-4, 6) of which are reported for the first time from this plant. The structures were determined by means...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.07.010
更新日期:2013-10-01 00:00:00
abstract::Salvianolic acid B (Sal B) is the most abundant phenolic compound in Salvia miltiorrhiza, which has been widely used for the treatment of cardiovascular diseases in Oriental medicine. To elucidate structure of the converted compounds of Sal B by decoction in aqueous solution, Sal B (200 mg) was decocted in an aqueous ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.06.015
更新日期:2012-10-01 00:00:00
abstract::Chiratone (1), a rare new chiratane type triterpenoid, together with five known triterpenoids were isolated from the rhizomes of Drynaria fortunei (Kunze) J. Sm. The structure was characterized as 20β-hydroxychiratan-22-one on the basis of extensive 1D and 2D NMR, and MS spectroscopic analyses, and was further confirm...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2010.06.013
更新日期:2010-12-01 00:00:00
abstract::One new resveratrol analogue, 1-(3',4',5'-trimethoxyphenyl)-2-methoxy-2-(4″-methoxyphenyl)-ethane-1-ol (1), and two new prenylisoflavones, 4'-hydroxy-5,7-dimethoxy-6-(3-methyl-2-butenyl)-isoflavone (2), and derrubon 5-methyl ether (3), together with 17 known compounds including one new natural product, 5,7-dihydroxy-3...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2014.03.015
更新日期:2014-06-01 00:00:00
abstract::Glabridin, a prenylated isoflavonoid of G. glabra L. roots (European licorice, Fabaceae), has been associated with a wide range of biological properties such as antioxidant, anti-inflammatory, anti-atherogenic, regulation of energy metabolism, estrogenic, neuroprotective, anti-osteoporotic, and skin-whitening. While g...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2013.07.003
更新日期:2013-10-01 00:00:00
abstract::Six previously undescribed compounds, named monaxanthones A and B, monaphenol A, monathioamide A, monaprenylindole A, and monavalerolactone A, were isolated from the culture of a marine-sourced bacterium Pseudomonas sp. ZZ820R in rice medium. Their structures were elucidated based on the HRESIMS data, NMR and MS-MS sp...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2020.104555
更新日期:2020-06-01 00:00:00
abstract::The species from Alangium have been used as folk medicine to treat rheumatism, skin diseases, diabetes by the people of Southeast Asia. Previous phytochemical studies have shown this genus are rich sources of alkaloids, glycosides, and terpenoids, which have attracted considerable attention of many researchers due to ...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2020.104773
更新日期:2020-11-01 00:00:00
abstract::The fruit rind of Garcinia gummi-gutta, commonly known as Garcinia cambogia (syn.), is extensively used traditionally as a flavourant in fish curries due to its sharp sour taste. Additional ethnobotanical uses include its use as a digestive and a traditional remedy to treat bowel complaints, intestinal parasites and r...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2015.02.012
更新日期:2015-04-01 00:00:00
abstract::European Hawthorn species (Crataegus spp.) are traditionally used for their demonstrated cardioprotective benefits. Most products are based on the compendial leaf and flower drug (LFD), which is standardised on the total flavonoid content (TF). In order to reduce variability associated with the wild plant origin and t...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2007.06.010
更新日期:2008-01-01 00:00:00
abstract:AIM:The current study was designed to explore the mechanism of the prokinetic activity of Gentiopicroside (Ge), from Gentiana macrophylla Pall which is widely used to strengthen gastric motility in clinic. METHODS:Gastrointestinal motility disorder rats were induced by stress stimulation and the rats were treated with...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.04.015
更新日期:2015-06-01 00:00:00
abstract::Antibacterial screening of petroleum ether, chloroform, ethyl acetate, methanol and aqueous extracts of Eupatorium glandulosum leaves exhibited a broad spectrum of inhibitory activity against Gram (+) and Gram (-) pathogenic bacteria. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2004.12.001
更新日期:2005-03-01 00:00:00
abstract::The present study investigates the effect of in vivo administration of alcoholic extract of Tinospora cordifolia whole plant (ALTC) on the proliferation and myeloid differentiation of bone marrow hematopoietic precursor cells in mice bearing a transplantable T cell lymphoma of spontaneous origin designated as Dalton's...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2005.05.002
更新日期:2006-01-01 00:00:00