Seladoeflavones A-F, six novel flavonoids from Selaginella doederleinii.

abstract：:In a two-microelectrode voltage clamp assay with Xenopus laevis oocytes, a petroleum ether extract (100 μg/mL) of the resin of Boswellia thurifera (Burseraceae) potentiated GABA-induced chloride currents (IGABA) through receptors of the subtype α₁β₂γ₂s by 319.8% ± 79.8%. With the aid of HPLC-based activity profiling, ...

journal_title：Fitoterapia

authors： Rueda DC,Raith M,De Mieri M,Schöffmann A,Hering S,Hamburger M

更新日期：2014-12-01 00:00:00

abstract：:Combinations of thyme, cowslip and liquorice roots are often used in the treatment of upper respiratory tract infections. Therefore the volatile fraction of herbal teas prepared from thyme (Thymus vulgaris) and the effect of combining with cowslip (Primula veris/P. elatior) and liquorice roots (Glycyrrhiza glabra) on ...

journal_title：Fitoterapia

authors： Tschiggerl C,Bucar F

更新日期：2011-09-01 00:00:00

abstract：:The present study was aimed to investigate the possible interaction of the standardized extract of Acorus calamus (AC) with Cytochrome P450 enzyme, quantitative determination of the α-asarone in the AC rhizome was performed by RP-HPLC method. In vitro interaction of the plant extract was evaluated by CYP450-carbon mon...

journal_title：Fitoterapia

authors： Pandit S,Mukherjee PK,Ponnusankar S,Venkatesh M,Srikanth N

更新日期：2011-04-01 00:00:00

abstract：:Sarcandracoumarin (1), the first coumarin having a 1-phenylethyl substituent at the C-3 position, was isolated along with eleven known phenolic compounds from the water extract of Sarcandra glabra. Its structure was elucidated on the basis of spectroscopic data. Compound 1 exhibited moderate or weak cytotoxicity again...

journal_title：Fitoterapia

authors： Feng S,Xu L,Wu M,Hao J,Qiu SX,Wei X

更新日期：2010-09-01 00:00:00

abstract：:Five new lanostane triterpenoids, ganoderic acid XL1 (1), ganoderic acid XL2 (2), 20-hydroxy-ganoderic acid AM1 (3), ganoderenic acid AM1 (4) and ganoderesin C (5), together with five known triterpenoids (6-10) were isolated from the fruiting bodies of Ganoderma theaecolum. Chemical structures were elucidated on the b...

journal_title：Fitoterapia

authors： Liu LY,Chen H,Liu C,Wang HQ,Kang J,Li Y,Chen RY

更新日期：2014-10-01 00:00:00

abstract：:European Hawthorn species (Crataegus spp.) are traditionally used for their demonstrated cardioprotective benefits. Most products are based on the compendial leaf and flower drug (LFD), which is standardised on the total flavonoid content (TF). In order to reduce variability associated with the wild plant origin and t...

journal_title：Fitoterapia

authors： Peschel W,Bohr C,Plescher A

更新日期：2008-01-01 00:00:00

abstract：:Five new phthalides (1-4, 6), two new natural products (5, 7) and five known phthalides (8-12) were isolated from the aerial parts of Ligusticum sinense Oliv cv. Chaxiong. Their structures were elucidated by HR-ESI-MS, UV, IR, 1D and 2D NMR (HSQC, HMBC, (1)H-(1)H COSY, NOESY) methods. The absolute configurations were ...

journal_title：Fitoterapia

authors： Wei Q,Yang J,Ren J,Wang A,Ji T,Su Y

更新日期：2014-03-01 00:00:00

abstract：:A new compound, 3beta,25-epoxy-3alpha-hydroxy-22beta-isobutanoyloxyolean-12-ene-28-oic acid (1), and two known triterpenoids lantanilic acid (2) and camaric acid (3) were isolated from the stem and leaves of Lantana cujabensis. Their structures were elucidated by spectroscopic methods. The ethanol extracts did not sho...

journal_title：Fitoterapia

authors： Okunade AL,Lewis WH

更新日期：2004-06-01 00:00:00

abstract：:Aqueous extract of Pteris multifida showed scavenging activities on DPPH, hydroxyl radicals and reducing power. ...

journal_title：Fitoterapia

authors： Wang TC,Ti MC,Lo SC,Yang CC

更新日期：2007-04-01 00:00:00

abstract：:Three undescribed polycyclic polyprenylated acylphloroglucinols (PPAPs) and three tocotrienols derivatives, named as paucinochymol A-F (1-3 and 10-12), together with six known PPAPs, were isolated from the fruits of Garcinia paucinervis. Their structures and absolute configurations were determined by extensive NMR ana...

journal_title：Fitoterapia

authors： Tan X,Zhong F,Teng H,Li Q,Li Y,Mei Z,Chen Y,Yang G

更新日期：2020-10-01 00:00:00

abstract：:The crude ethanol extract from the leaves of Zanthoxylum liebmannianum exhibited inhibitory effect on the reproduction of trophozoites of Entamoeba histolytica (IC(50)=3.48 microg/ml) and Giardia lamblia (IC(50)=58.00 microg/ml). From this extract, asarinin, hyperin, beta-sitosterol, and beta-sitosterol glucoside were...

journal_title：Fitoterapia

authors： Arrieta J,Reyes B,Calzada F,Cedillo-Rivera R,Navarrete A

更新日期：2001-03-01 00:00:00

abstract：:Two new dimeric diarylheptanoids, named Alpinin C (1) and D (2), a new natural product of diarylheptanoid (3) along with three known diarylheptanoids (4-6) were isolated from the rhizomes of Alpinia officinarum Hance. Their structures were elucidated based on extensive spectroscopic analyses (1D and 2D NMR, HRTOFMS, I...

journal_title：Fitoterapia

authors： Liu D,Liu YW,Guan FQ,Liang JY

更新日期：2014-07-01 00:00:00

abstract：:Two new compounds, 6-oxo-20-hydroxy-20-epi-tingenol (1) and 2R*,3R*,5S*-trihydroxy-6R*-nonadecyltetrahydropyran-4-one (2), were isolated from the pericarp of Glyptopetalum sclerocarpum along with other 10 constituents. ...

journal_title：Fitoterapia

authors： Sotanaphun U,Lipipun V,Bavovada R

更新日期：2004-09-01 00:00:00

abstract：:Four new dihydrophenanthrenofuran, bleochranols A-D (1-4), along with 21 known compounds including phenanthrenes (5-14) and bibenzyls (15-25) were isolated and elucidated from the rhizomes of Bletilla ochracea. Combination of 1D/2D NMR techniques and the Electronic Circular Dichroism (ECD) spectroscopy based on the em...

journal_title：Fitoterapia

authors： Li JY,Kuang MT,Yang L,Kong QH,Hou B,Liu ZH,Chi XQ,Yuan MY,Hu JM,Zhou J

更新日期：2018-06-01 00:00:00

abstract：:In the last 20 years, wine phenolic compounds have received increasing interest since several epidemiological studies have suggested associations between regular consumption of moderate amount of wine and prevention of certain chronic pathologies, such as neurodegenerative diseases. This study was aimed to investigate...

journal_title：Fitoterapia

authors： Giacoppo S,Galuppo M,Lombardo GE,Ulaszewska MM,Mattivi F,Bramanti P,Mazzon E,Navarra M

更新日期：2015-06-01 00:00:00

abstract：:The irritant potential of total methanolic extract and five triterpenoids newly isolated from the leaves of Ficus carica investigated by open mouse ear assay. Total methanolic extract, calotropenyl acetate, methyl maslinate and lupeol acetate showed potent and persistent irritant effects. ...

journal_title：Fitoterapia

authors： Saeed MA,Sabir AW

更新日期：2002-08-01 00:00:00

abstract：:Ganoderma cochlear, as edible and medicinal fungus, has long been used to prevent and treat various diseases. As our continuously phytochemical investigation of this fungus, a HPLC-UV-guided method led to the isolation of nine previously undescribed aromatic meroterpenoids with different ring systems, including six pa...

journal_title：Fitoterapia

authors： Peng X,Wang X,Chen L,Yang H,Li L,Lu S,Zhou L,Qiu M

更新日期：2018-06-01 00:00:00

abstract：:The pharmacological active genus Thymus L. comprises over 200 species. Besides its traditional pharmacological use, thyme may reduce the risk of caries disease, however, there is very little respective literature. The pharmacological effects can be attributed to the secondary plant metabolites. The composition of the ...

journal_title：Fitoterapia

authors： Schött G,Liesegang S,Gaunitz F,Gleß A,Basche S,Hannig C,Speer K

更新日期：2017-09-01 00:00:00

abstract：:Three new cycloartane triterpenoids (1-3) and two known compounds (4, 5) were isolated from the whole plant of Beesia calthaefolia. Their structures were elucidated by 1D and 2D NMR, HRESIMS and optical rotation spectral data. All isolates were investigated for their inhibitory effects on the classical pathway of the ...

journal_title：Fitoterapia

authors： Mu LH,Li HJ,Guo DH,Zhao JY,Liu P

更新日期：2014-01-01 00:00:00

abstract：:NAtural Deep Eutectic Solvents (NADES) are chemically simple but physiologically important plant constituents that exhibit unique solubilizing properties of other metabolites, including bioactive constituents. The high polarity of NADES introduces a challenge in the ability of conventional solid-support based chromato...

journal_title：Fitoterapia

authors： Liu Y,Garzon J,Friesen JB,Zhang Y,McAlpine JB,Lankin DC,Chen SN,Pauli GF

更新日期：2016-07-01 00:00:00

abstract：:A new coumestan, 1,3,9-trihydroxy-8-methoxycoumestan, named flemicoumestan A 1 together with nine isoflavone-related compounds were isolated from the ethyl acetate extract of the roots of Flemingia philippinensis. Their structures were elucidated and confirmed by spectroscopic methods and literature data. Compounds 3 ...

journal_title：Fitoterapia

authors： Li L,Deng X,Zhang L,Shu P,Qin M

更新日期：2011-06-01 00:00:00

abstract：:The effect of asiaticoside isolated from Hydrocotyle sibthorpioides (AHS) on the promotion of cognition in senescence-accelerated mice (SAMP) was evaluated. Six-month old male SAMP8 mice were orally administered 20, 40 or 80 mg/kg AHS daily for three months. SAMR1 mice were used as a "normal aging" control. The result...

journal_title：Fitoterapia

authors： Lin X,Huang R,Zhang S,Wei L,Zhuo L,Wu X,Tang A,Huang Q

更新日期：2013-06-01 00:00:00

abstract：:Aqueous extract of the stem bark of Mangifera indica and ethanolic extract of the roots of Pluchea ovalis has been studied on rat tracheal smooth muscle in vitro. The extract of M. indica at 1, 2 and 4 mg/ml and that of P. ovalis at 0.25, 0.5 and 1 mg/ml relaxed, dose-dependently, the rat tracheal smooth muscle strip ...

journal_title：Fitoterapia

authors： Agbonon A,Eklu-Gadegbeku K,Aklikokou K,Essien K,Akpagana K,Gbeassor M

更新日期：2002-12-01 00:00:00

abstract：:The flavonoid baicalein has been demonstrated to be an activator of the transcription factor Nrf2 in mammalian cell lines. We show that it further modulates the Nrf2 homolog SKN-1 in Caenorhabditis elegans and by this pathway mediates beneficial effects in the nematode: baicalein enhances the resistance of C. elegans ...

journal_title：Fitoterapia

authors： Havermann S,Humpf HU,Wätjen W

更新日期：2016-09-01 00:00:00

abstract：:Three new clerodane type diterpenoids (2-4), together with one known analogues (1), were isolated from the tuberous roots of Tinospora sagittata (Oliv.) Gagnep. Compound 3 is an unusual clerodane diterpenoid with the carbonyl functionality at C-3, which represents the first example from this diterpenoid compounds clas...

journal_title：Fitoterapia

authors： Zhang G,Ma H,Hu S,Xu H,Yang B,Yang Q,Xue Y,Cheng L,Jiang J,Zhang J,Wang F,Zhang Y

更新日期：2016-04-01 00:00:00

abstract：:The furanocoumarin imperatorin has been reported to have hypotensive effect, and we have investigated its activity on myocardial hypertrophy. Imperatorin displayed similar chromatographic retention peak to verapamil in the model of cardiac muscle/cell membrane chromatography, and could reduce in a concentration-depend...

journal_title：Fitoterapia

authors： Zhang Y,Cao Y,Zhan Y,Duan H,He L

更新日期：2010-12-01 00:00:00

abstract：:6,7-Dimethylesculetin (D), geniposide (G) and rhein (R) are the three major active ingredients of Yin-Chen-Hao-Tang (YCHT), a famous Chinese herbal formula, which has been shown to be clinically effective for treating hepatic injury (HI) syndrome. The present study was conducted to investigate the therapeutic and syne...

journal_title：Fitoterapia

authors： Zhang A,Sun H,Yuan Y,Sun W,Jiao G,Wang X

更新日期：2011-12-01 00:00:00

abstract：:A sensitive and specific HPLC method was developed to analyze baicalin in rat plasma. The author had compared the pharmacokinetics of baicalin after oral administration of HLJDT decoction or pure baicalin in MCAO and sham-operated rats. All the rats were divided into two groups, MCAO and sham-operated rats. Each group...

journal_title：Fitoterapia

authors： Zeng MF,Pan LM,Zhu HX,Zhang QC,Guo LW

更新日期：2010-09-01 00:00:00

abstract：:Cassia occidentalis L. is an annual or perennial Ayurvedic plant which is used in several traditional medicines to cure various diseases. This weed has been known to possess antibacterial, antifungal, antidiabetic, anti-inflammatory, anticancerous, antimutagenic and hepatoprotective activity. A wide range of chemical ...

journal_title：Fitoterapia

authors： Yadav JP,Arya V,Yadav S,Panghal M,Kumar S,Dhankhar S

更新日期：2010-06-01 00:00:00

abstract：:A new triterpene, 3beta-19alpha-dihydroxy-30-norurs-12-ene (1), has been isolated from the methanolic extract of Debregeasia salicifolia stems. Its structure has been elucidated with the help of one- and two-dimensional NMR and NOE studies. Lupeol, beta-sitosterol, stigmasterol and oleanolic acid are also reported for...

journal_title：Fitoterapia

authors： Akbar E,Riaz M,Malik A

更新日期：2001-05-01 00:00:00