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Triterpenoids of Ganoderma theaecolum and their hepatoprotective activities.

Abstract：

:Five new lanostane triterpenoids, ganoderic acid XL1 (1), ganoderic acid XL2 (2), 20-hydroxy-ganoderic acid AM1 (3), ganoderenic acid AM1 (4) and ganoderesin C (5), together with five known triterpenoids (6-10) were isolated from the fruiting bodies of Ganoderma theaecolum. Chemical structures were elucidated on the basis of spectroscopic evidence, including 1D, 2D NMR, mass spectrometric data and circular dichroism spectra. Compounds 1, 4, 5, 8, 9 and 10 (10 μM) exhibited hepatoprotective activities against DL-galactosamine-induced cell damage in HL-7702 cells.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Liu LY,Chen H,Liu C,Wang HQ,Kang J,Li Y,Chen RY

doi

10.1016/j.fitote.2014.08.004

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

254-9

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(14)00218-4

journal_volume

98

pub_type

杂志文章

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