Abstract：
:Panax ginseng is an indigenous medicinal herb and has traditionally been used among Asian population for relief of many human ailments. We investigated the prophylactic role of Korean P. ginseng extract (KG) against X-ray irradiation-induced emesis in an acute rat pica model. Rats were treated with KG (12.5, 25, 50 mg/kg orally at -48, -24 and 0 h) prior to X-ray irradiation (6 Gy), and intake of kaolin and normal food and body weight changes examined as an index of the acute emetic stimulus. Levels of serotonin in small intestine tissue were assessed and histopathology of gastric tissue, small intestine and colon examined specific staining. Pre-treatment with KG (12.5 and 25 mg/kg) reduced X-ray irradiation-induced kaolin intake at 24h. Normal food intake was improved in rats treated with 25 mg/kg KG. The anti-emetic effect of KG was further confirmed on the basis of serotonin release, histopathological findings. Our findings collectively indicate that KG protects against X-ray irradiation-induced acute pica to a moderate extent, leading to improved feeding behavior in rats.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Balaji Raghavendran HR,Rekha S,Cho HK,Jang SS,Son CGdoi
10.1016/j.fitote.2012.04.008subject
Has Abstractpub_date
2012-09-01 00:00:00pages
1144-50issue
6eissn
0367-326Xissn
1873-6971pii
S0367-326X(12)00115-3journal_volume
83pub_type
杂志文章相关文献
FITOTERAPIA文献大全abstract：:The antimicrobial activity of ethanol, acetone and aqueous extracts of the aerial parts of Pseudognaphalium moritzianum was evaluated. Ethanol and acetone extracts showed activity against Staphlococcus aureus, Enterococcus faecalis and Pseudomonas aeruginosa. The aqueous extract was active against S. aureus and P. aer...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(02)00219-8
更新日期：2002-12-01 00:00:00
abstract：:Aloe vera gel is a familiar ingredient in a range of widely available and advertisement healthcare and cosmetic products. As to date there are no documented reports on the standardization of A. vera gel and the following study is an attempt in this direction. A. vera gel was evaluated for its aloeverose content for th...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2009.09.001
更新日期：2010-06-01 00:00:00
abstract：:The alpha7 nicotinic acetylcholine receptor (nAChR) is a potential target in neuroinflammation. Screening a plant extract library identified Solidago nemoralis as containing methyl-quercetin derivatives that are relatively selective ligands for the alpha7 nAChR. Flavonoids are not known for this activity, so we screen...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2014.06.012
更新日期：2014-10-01 00:00:00
abstract：:Pocahemiketals A and B (1 and 2), two novel hemiketal sesquiterpenoids with unprecedented skeletons, were isolated from the essential oil of the aerial parts of Pogostemon cablin. In addition to a bicyclo[3.2.1]-carbon core, 1 and 2 possessed a hemiketal α,β-unsaturated-γ-lactone moiety. Their structures were determin...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2017.05.013
更新日期：2017-07-01 00:00:00
abstract：:The effect of berberine hydrochloride (BBR) on inducible cyclooxygenase-2 (COX-2) in small intestinal mucosa and related mechanisms was investigated in a rat model of acute endotoxemia. The results showed that lipopolysaccharide (LPS) increased COX-2 expression, whereas SB202190 and BBR curtailed it. LPS increased pho...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2011.05.013
更新日期：2011-10-01 00:00:00
abstract：:Curcuminoids possess powerful antioxidant activity as demonstrated in many chemical in vitro tests and in several in vivo trials. Nevertheless, the mechanism of this activity is not completely elucidated and studies on the in vivo antioxidant effects are still needed. Metabolomics may be used as an attractive approach...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2015.12.013
更新日期：2016-03-01 00:00:00
abstract：:Picrasamide A (1), a new cinnamamide derivative, together with two new β-carboline alkaloids (2 and 3) and five known β-carboline alkaloids (4-8) were isolated from the stems of Picrasma quassioides (D. Don) Benn. Their structures were elucidated by detailed analyses of UV, IR, HRESIMS, and NMR data. Compound 1 was th...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2019.104375
更新日期：2019-11-01 00:00:00
abstract：:Five new cytochalasans (1-5) were isolated from the rice fermentation of fungus Xylaria longipes, along with seven known compounds cytochalasin P (6), cytochalasin D (7), zygosporin D (8), 7-O-acetylcytochalasin D (9), cytochalasin C (10), 6,7-dihydro-7-oxo-cytochalasin C (11), and 6,7-dihydro-7-oxo-deacetylcytochalas...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2019.104278
更新日期：2019-09-01 00:00:00
abstract：:A phytochemical study of an ethanol-soluble extract from the root barks of Daphne tangutica Maxim., a traditional Tibetan herb medicine, led to the isolation of 30 compounds, including eight daphnane diterpenes, nine coumarines, six lignans, five phenylpropanoid derivatives, beta-sitosterol and p-hydroxy benzonate. Tw...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2009.07.002
更新日期：2010-01-01 00:00:00
abstract：:Seventy-six plant species from 46 botanical families, traditionally used to treat intestinal diseases in Mbalmayo region are recorded. The local names and the way the plants are used are indicated. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(00)00288-4
更新日期：2001-03-01 00:00:00
abstract：:A chemical investigation of the 80% EtOH extract of the aerial plant of Alstonia rupestris afforded four new monoterpenoid indole alkaloids, 6,7-epoxy-8-oxo-vincadifformine (1), 11-acetyl-6,7-epoxy-8-oxo-vincadifformine (2), 11-hydroxy-14-chloro-15-hydroxy-vincadifformine (3), and perakine N1,N4-dioxide (4), together ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2014.05.018
更新日期：2014-09-01 00:00:00
abstract：:The antioxidant activity of Citrus paradisi (grapefruit) seeds glyceric extract dissolved in ethanol and in aqueous media was evaluated using three different methods: evaluation by DPPH assay, by 5-lipoxygenase assay and by luminol/xanthine/xanthine oxidase chemiluminescence assay. The total phenolic content was deter...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2003.12.010
更新日期：2004-03-01 00:00:00
abstract：:The antituberculosis activity of 14 natural azorellane and mulinane diterpenoids isolated from Azorella compacta, Azorella madreporica, Mulinum crassifolium, and Laretia acaulis, together with eight semisynthetic derivatives, was evaluated against two Mycobacterium tuberculosis strains. The natural azorellanes azorell...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2009.07.005
更新日期：2010-01-01 00:00:00
abstract：:Centella asiatica (L.) Urban is a medicinal herb traditionally used in Asiatic countries for its multiple therapeutic properties, essentially due to its accumulation of specific pentacylic triterpenoid saponins, mainly asiaticoside and madecassoside and the corresponding sapogenins. This review summarizes the updated ...
journal_title：Fitoterapia
pub_type： 杂志文章,评审
doi：10.1016/j.fitote.2016.07.011
更新日期：2016-10-01 00:00:00
abstract：:Rheum palmatum Linn has been widely applied in the clinical treatment of diabetes mellitus. It has been found that emodin as the major bioactive component of R. palmatum L exhibits the competency to activate peroxisomal proliferator-activated receptor-gamma (PPARgamma) in vitro. So the aim of this study was to evaluat...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2009.08.020
更新日期：2010-04-01 00:00:00
abstract：:The composition of the essential oil of Lindera neesiana Kurz fruit was examined by GC-MS, (1)H, (13)C and bidimensional NMR techniques (HMQC, HMBC, COSY, TOCSY). Forty compounds were identified, representing approximately 86% of the oil: Z-citral (15.08%), E-citral (11.89%), eucalyptol (8.75%), citronellal (6.72%), a...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2009.06.017
更新日期：2010-01-01 00:00:00
abstract：:Since the extract from berries of Aronia melanocarpa presents antioxidative properties in plasma and in blood platelets, not only from healthy group, but also from patients with benign breast diseases and in patients with invasive breast cancer before surgery, the aim of our present study was to evaluate the oxidative...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2011.11.007
更新日期：2012-03-01 00:00:00
abstract：:Phytochemical study on rhizomes of Beesia calthifolia resulted in the isolation of five new (1-5) and three known (6-8) cycloartane triterpenoids possessing a hemiketal or ketal group at C-24 from the EtOAc fraction of 95% ethanol extract. Their structures were determined by spectroscopic and chemical methods, especia...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2015.04.017
更新日期：2015-06-01 00:00:00
abstract：:The cytotoxic effects of seven constituents isolated from Duguetia glabriuscula were evaluated against Hep2 human larynx carcinoma cells. The cytotoxicity exhibited by beta-sitosterol was as strong as that of cis-platin. (+)-Alloaromadendran-10,14beta-diol caused inhibition of cellular growth with IC50 values lower th...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2006.01.013
更新日期：2006-04-01 00:00:00
abstract：:Three lignans, pinoresinol (1), 8-hydroxypinoresinol (2) and olivil (3) have been isolated from the leaves of Strophanthus gratus by reversed-phase HPLC. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(00)00240-9
更新日期：2001-01-01 00:00:00
abstract：:Three new mixed terpenoids, tricycloalternarenes (TCAs) F-H (1-3), together with ten known tricycloalternarenes (4-13), were isolated from the Czapek's culture of an endophytic fungus Ulocladium sp. Their structures were identified by extensive spectroscopic experiments (NMR and MS) and comparison with literature data...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2012.12.029
更新日期：2013-03-01 00:00:00
abstract：:Tithonia diversifolia (Asteraceae), is used as traditional medicine in tropical countries for the treatment of various diseases, including malaria. Although numerous studies have assessed the antimalarial properties, nothing is known about the effect of T. diversifolia extracts on trypanosomiasis. In this study extrac...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2017.11.002
更新日期：2018-01-01 00:00:00
abstract：:Before the design of brucine-containing transdermal formulations, the pharmacodynamics and pharmacokinetics of brucine following transdermal administration should be evaluated. In this study, the effect of addition of ethanol on solubility of bruicne was investigated and 20% ethanol was added into PBS to obtain 10mg/m...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.03.007
更新日期：2013-04-01 00:00:00
abstract：:Anti-nociceptive and anti-oedematogenic effects of the aqueous extract from the leaves of Erythrina velutina were tested through experimental models of nociception in mice and paw oedema induced by carrageenin in rats. The extract (300 and 600 mg/kg) did not change the carrageenin-induced paw oedema. In the hot plate ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2005.07.002
更新日期：2005-12-01 00:00:00
abstract：:The aqueous extract of the Cocculus hirsutus aerial parts (100 and 200 mg/kg, p.o.) showed significant diuretic activity and laxative effect in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(01)00345-8
更新日期：2002-02-01 00:00:00
abstract：:Four new aristolochic acid derivatives aristchamic A (1), aristchamic B (2), aristochamic C (3a), aristchamic D (3b) and one new aristolactam aristolactam-CV (4), together with 10 known compounds (5-14), were isolated from the rhizomes of Aristolochia championii. Their structures were assigned by detailed analysis of ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2017.01.006
更新日期：2017-04-01 00:00:00
abstract：:Five new ursane-type triterpenoids, spicatusoids A-E (1, 3-6), and three known ones (2, 7, and 8), and a known oleanane-type triterpenoid (9) were isolated from the aerial parts of Clerodendranthus spicatus. Their structures were elucidated by spectroscopic methods. In particular, the structure of 3 including its abso...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2017.04.001
更新日期：2017-06-01 00:00:00
abstract：:Two new alkaloids were isolated from the bark of Sarcomelicope megistophylla. Cyclomegistine B (1), a new quinolone alkaloid, that possesses a rare cyclobuta[b]quinoline ring system and sarcomejine B (2) which is a quinolone alkaloid with an unusual side chain. The structure of both compounds was elucidated on the bas...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2006.10.003
更新日期：2007-02-01 00:00:00
abstract：:Two new glycosides, 2-methyl-L-erythritol-4-O-(6-O-trans-sinapoyl)-β-D-glucopyranoside (1) and 2-methyl-L-erythritol-1-O-(6-O-trans-sinapoyl)-β-D-glucopyranoside (2), along with two known triterpenoids (3-4), four quinic acid derivatives (5-8) and one flavonoid (9) were isolated from the fruit of Gardenia jasminoides....
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.05.018
更新日期：2013-09-01 00:00:00
abstract：:alpha(2)beta(1) and alpha(IIb)beta(3) integrins, that support platelet adhesion to collagen and fibrinogen, respectively, share common signaling molecules. The effect of quercetin on platelet static adhesion to collagen and fibrinogen was assessed and correlated with its kinase inhibitory activity. Quercetin strongly ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2009.08.006
更新日期：2010-03-01 00:00:00
