Abstract：
:Picrasamide A (1), a new cinnamamide derivative, together with two new β-carboline alkaloids (2 and 3) and five known β-carboline alkaloids (4-8) were isolated from the stems of Picrasma quassioides (D. Don) Benn. Their structures were elucidated by detailed analyses of UV, IR, HRESIMS, and NMR data. Compound 1 was the first case of cinnamamide derivative from genus Picrasma. The AChE inhibitory activity and the antimicrobial activity of 1-8 were assessed. In addition, preliminary structure-activity relationships of these β-carboline alkaloids on the AChE inhibitory activity and antimicrobial activity were proposed.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Zhang J,Wang CX,Song XJ,Li S,Fan CL,Chen GD,Hu D,Yao XS,Gao Hdoi
10.1016/j.fitote.2019.104375subject
Has Abstractpub_date
2019-11-01 00:00:00pages
104375eissn
0367-326Xissn
1873-6971pii
S0367-326X(19)31930-6journal_volume
139pub_type
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