Abstract：
:Four new aristolochic acid derivatives aristchamic A (1), aristchamic B (2), aristochamic C (3a), aristchamic D (3b) and one new aristolactam aristolactam-CV (4), together with 10 known compounds (5-14), were isolated from the rhizomes of Aristolochia championii. Their structures were assigned by detailed analysis of MS and NMR spectroscopic data. All of the isolated compounds were evaluated for their cytotoxic activities against HCT-116, HepG2, BGC-823, NCI-H1650, and A2780 cell. Compound 1 exhibited significant cytotoxic activity against HCT-116, HepG2, BGC-823, and NCI-H1650, with IC50 values of 0.50, 7.37, 2.66, and 0.75μM, respectively.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Wang X,Shi GR,Liu YF,Li L,Chen RY,Yu DQdoi
10.1016/j.fitote.2017.01.006subject
Has Abstractpub_date
2017-04-01 00:00:00pages
63-68eissn
0367-326Xissn
1873-6971pii
S0367-326X(16)31022-Xjournal_volume
118pub_type
杂志文章相关文献
FITOTERAPIA文献大全abstract：:Traditional Indonesian medicinal plants were screened for their inhibitory effects on the nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages and for the antioxidant activity through the evaluation of free radical scavenging effect and reducing power. The results of screening indic...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2004.11.010
更新日期：2005-03-01 00:00:00
abstract：:Five new benzylphenanthrenes, cremaphenanthrenes L-P (1-5) were isolated from the EtOAc-soluble extract of the tubers of Cremastra appendiculata. Their structures were elucidated based on the spectroscopic data and chemical methods. Compounds 1-5 were tested in vitro for their cytotoxic effects against colon (HCT-116)...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2015.03.003
更新日期：2015-06-01 00:00:00
abstract：:Phytochemical studies on the ethanol extract of the aerial parts of Ecdysanthera rosea led to the isolation of three new compounds, hydroquinone diglycoside acyl esters, ecdysanrosin A (1) and sesquiterpene, 5β-hydroperoxycostic acid (2) and apocarotenoid, 2, 4, 7-trimethyl-2, 4, 6, 8-tetraene-dialdehyde (3). Their st...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2010.06.001
更新日期：2010-10-01 00:00:00
abstract：:Activity-guided fractionation of the methanol extract of Vitis vinifera bark led to the isolation of epsilon-viniferin, ampelopcin A, vitisin A and vitisin B. Vitisin A and vitisin B showed a remarkable inhibitory activity against 3-hydroxy-3-methylglutaryl-Coenzyme A (HMG-CoA) reductase with IC50 value of 42.1 microM...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2007.11.005
更新日期：2008-04-01 00:00:00
abstract：:Eight new dihydrobenzofuran neolignans, pinnatifidanin C I-VIII (1-8), together with two known analogs (9-10) were isolated from the seeds of Crataegus pinnatifida. Their structures were elucidated by spectroscopic analyses, especially 1D, 2D NMR and CD spectra. The cytotoxic activities of all isolates against human c...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.09.011
更新日期：2013-12-01 00:00:00
abstract：:A new lathyrane diterpene (1), an unreported spectroscopic data lathyrane diterpenene (2), and two known analaogues (3 and 4) have been isolated from Euphorbia prolifera. Their structures were elucidated as (12E,2S,3S,4R,5R,6S,9S,11S,15R)-3-butyryloxy-5,15-diacetoxy-6,17-epoxylathyra- 12-en-14-one (1), (12E,2S,3S,4R,5...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2012.06.014
更新日期：2012-10-01 00:00:00
abstract：:Two new 7,6'-coupled naphthylisoquinolines, namely ancistrotectorines A (1) and B (2), two new 5,3'-coupled naphthylisoquinolines, namely ancistrotectorines C (3) and D (4), and one new 7,8-coupled naphthylisoquinoline, namely ancistrotectorine E (5), together with 9 known naphthylisoquinoline alkaloids, hamatine (6),...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.09.010
更新日期：2013-12-01 00:00:00
abstract：:Zuo-Jin-Wan (ZJW) has been used to treat hepatocellular carcinoma in Asia. This study was to determine whether ZJW and its components blocked activator protein 1 (AP-1) and nuclear factor-κB (NF-κB) activities as well as tumor promotion in hepatoblastoma HepG2 cells. ZJW and its components, Coptis chinensis and Evodia...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2011.02.009
更新日期：2011-06-01 00:00:00
abstract：:Oplopanax horridus or devil's club is a herbal medicine distributed in North America. The constituents and pharmacological activities of O. horridus (OPH) are largely unknown. In this study, we assayed OPH stem and berry extracts using high performance liquid chromatography (HPLC). The anticancer potentials of extract...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2009.08.003
更新日期：2010-03-01 00:00:00
abstract：:Nineteen secolignans (1-19), including five new ones (1-5), were isolated from the whole plant of Peperomia dindygulensis. Their structures including stereochemistry were determined by spectroscopic methods, in particular NMR and electronic CD (ECD) analysis. All the isolates were evaluated for their inhibitory activi...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2017.08.018
更新日期：2017-10-01 00:00:00
abstract：:A fast and efficient method for the isolation of the C-glucosidated xanthones mangiferin and isomangiferin from the South-African plant Cyclopia genistoides was developed for the first time. The procedure involved extraction, liquid-liquid partitioning with ethyl acetate and subsequent precipitation of mangiferin and ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.07.020
更新日期：2013-10-01 00:00:00
abstract：:The flavonoid fraction of Tephrosia purpurea (FFTP) was studied for its effect on cellular and humoral functions and on macrophage phagocytosis in mice. Oral administration of FFTP (10-40 mg/kg) significantly inhibited sheep red blood cells (SRBC)-induced delayed-type hypersensitivity reactions. It also produced a sig...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(03)00042-x
更新日期：2003-04-01 00:00:00
abstract：:7-O-methylvariecolortide A (1), variecolortide B (2), and variecolortide C (3), the rare variecolortides existing in racemic manner, were isolated from an endolichenic fungal strain Eurotium sp. (No. 17-11-8-1). With the chiral HPLC technology, (-)-(S)-7-O-methylvariecolortide A (1a), (+)-(R)-7-O-methylvariecolortide ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.11.012
更新日期：2014-01-01 00:00:00
abstract：:Extracts of roots of Rumex nepalensis, Berberis aristata, Arnebia benthamii, bark of Taxus wallichiana, Juglans regia and petals of Jacquinia ruscifolia were tested for their antifungal activity against twelve different fungal pathogens. Ethanolic extracts of R. nepalensis and J. ruscifolia extracts showed a broad spe...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2008.06.004
更新日期：2008-12-01 00:00:00
abstract：:Before the design of brucine-containing transdermal formulations, the pharmacodynamics and pharmacokinetics of brucine following transdermal administration should be evaluated. In this study, the effect of addition of ethanol on solubility of bruicne was investigated and 20% ethanol was added into PBS to obtain 10mg/m...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.03.007
更新日期：2013-04-01 00:00:00
abstract：:Epiberberine, a natural protoberberine from Coptis chinensis Franch., is a potential alkaloid for the treatment of a variety of chronic diseases. The aim of this study is to summarize recent advances in the multiple and potential therapeutic effects of epiberberine. High-quality researches published in last two decade...
journal_title：Fitoterapia
pub_type： 杂志文章,评审
doi：10.1016/j.fitote.2020.104771
更新日期：2020-11-01 00:00:00
abstract：:Psychotria is a complex genus whose neotropical species are known by the presence of glucosidic monoterpene indole alkaloids. These compounds are able to display a large range of effects on the central nervous system, such as anxiolytic, antidepressant, analgesic, and impairment of learning and memory acquisition. The...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2012.04.013
更新日期：2012-09-01 00:00:00
abstract：:A new altersolanol derivative, 4-dehydroxyaltersolanol A (9), along with two known sesquiterpenoids, (S)-7'-hydroxyabscisic acid (7) and (S)-abscisic acid (8) were obtained from the endophytic fungus, Nigrospora oryzae, isolated from leaves of Combretum dolichopetalum. The host plant yielded six known compounds includ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2015.06.018
更新日期：2015-09-01 00:00:00
abstract：:Successive petroleum ether, dichloromethane and methanol extracts of Ajuga remota aerial parts were tested in vitro for their antifungal activity. The petroleum ether fraction was found to be the most effective against the tested pathogens. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(00)00280-x
更新日期：2001-02-01 00:00:00
abstract：:Two new guaiane-type sesquiterpenoids containing an interesting epoxy unit, daucuside (1) and daucusol (2) were isolated from the fruits of Daucus carota L. Their chemical structures were elucidated on the basis of MS, NMR spectroscopic analyses coupled with chemical degradation and they were also evaluated for the cy...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2009.12.008
更新日期：2010-07-01 00:00:00
abstract：:The effect of schisandrin B (Sch B) on long-term ethanol-induced oxidative stress in various rat tissues was investigated. Long-term ethanol treatment increased reactive oxygen metabolites (ROM) level in plasma. The ethanol-induced oxidative stress was assessed by mitochondrial glutathione and α-tocopherol levels, ant...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2010.08.010
更新日期：2010-12-01 00:00:00
abstract：:A new cardenolide, 16,17-dihydroneridienone 3-O-beta-D-glucopyranosyl-(1-->6)-O-beta-D-galactopyranoside (1), was isolated from the roots of Terminalia arjuna. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(00)00337-3
更新日期：2001-05-01 00:00:00
abstract：:Largely widespread in tropical countries, Ocimum gratissimum has been claimed for many uses in folk medicine. Recent research on its essential oils showed five chemotypes. An Indian chemotype, with a high level of ethyl cinnamate, presents, in vitro, an interesting spectrum of antifungal properties. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(00)00206-9
更新日期：2000-09-01 00:00:00
abstract：:Diterpene alkaloids neoline (1), napelline (2), isotalatizidine (3), karakoline (4), senbusine A (5), senbusine C (6), aconitine (7) and taurenine (8) were identified from Aconitum napellus L. subsp. firmum, four (2-4, 6) of which are reported for the first time from this plant. The structures were determined by means...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.07.010
更新日期：2013-10-01 00:00:00
abstract：:Four new C18-diterpenoid alkaloids, weisaconitines A-D (1-4), were isolated from Aconitum weixiense. Based on extensive UV, IR, MS, 1D and 2D NMR analyses, their structures were elucidated as 8-O-ethyldolaconine (1), 4-demethylgenicunine B (2), 14-oxoaconosine (3), and 8-O-ethylaconosine (4). The analgesic activity of...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.09.013
更新日期：2013-12-01 00:00:00
abstract：:The alkaloidal fraction obtained from an ethanolic extract of the leaves of Mikania cordata exhibited significant in vivo antiulcer activity in diclofenac sodium-induced gastric erosions in Long Evans rats. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(00)00216-1
更新日期：2000-12-01 00:00:00
abstract：:Four new sesquiterpenes (1-2, 6-7), a new pyranone glycoside (10) along with six known compounds, were isolated from the whole plant of Erigeron breviscapus. Their planar structures were elucidated using extensive spectroscopic analyses. Brevisterpene A (1) and brevisterpene B (2) were proved to be a pair of diastereo...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2019.104288
更新日期：2019-10-01 00:00:00
abstract：:The isolation of five flavonol glycosides (1-5) from the flowers of Aconitum vulparia is reported, together with the 1H- and 13C-NMR spectral data in CD(3)OD of compound 3 and 5. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(03)00045-5
更新日期：2003-06-01 00:00:00
abstract：:Sauruchinenols A (1) and B (2), two novel monocyclic diterpenes with unique carbon skeleton, as well as two new structurally related diterpenes, sauruchinenols C (3) and D (4), were isolated from the aerial part of Saururus chinensis. Their structures were elucidated based on the analysis of spectroscopic data. A hypo...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2016.11.018
更新日期：2017-01-01 00:00:00
abstract：:A different type of biologically active compound from Kuji amber (Late Cretaceous, Japan) before the K-Pg boundary [65 million years ago (Ma)] was isolated based on the growth-restoring activity of a mutant yeast involving Ca2+ signal transduction. It was identified as a spirolactone norditerpenoid, (4R*, 5S*, 8R*, 9R...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2019.02.027
更新日期：2019-04-01 00:00:00
