Flavonol glycosides from Aconitum vulparia.

abstract：:Bergamot juice produces hypolipemic activity in rats though the mechanism remains unclear. Here we investigated on the effect of bergamot extract (BPF) in diet-induced hyperlipemia in Wistar rats and in 237 patients suffering from hyperlipemia either associated or not with hyperglycaemia. BPF, given orally for 30 days...

journal_title：Fitoterapia

authors： Mollace V,Sacco I,Janda E,Malara C,Ventrice D,Colica C,Visalli V,Muscoli S,Ragusa S,Muscoli C,Rotiroti D,Romeo F

更新日期：2011-04-01 00:00:00

abstract：:Before the design of brucine-containing transdermal formulations, the pharmacodynamics and pharmacokinetics of brucine following transdermal administration should be evaluated. In this study, the effect of addition of ethanol on solubility of bruicne was investigated and 20% ethanol was added into PBS to obtain 10mg/m...

journal_title：Fitoterapia

authors： Chen J,Hu W,Qu YQ,Dong J,Gu W,Gao Y,Fang Y,Fang F,Chen ZP,Cai BC

更新日期：2013-04-01 00:00:00

abstract：:This paper reports the results of an ethnobotanical survey of medicinal plants used by the Thari people of the Nara Desert, Sindh, Pakistan. Fifty-one plant species distributed across 28 families and 43 genera were discovered to have medicinal uses by local inhabitants of the Nara Desert. Twenty-one of those species a...

journal_title：Fitoterapia

authors： Qureshi R,Raza Bhatti G

更新日期：2008-09-01 00:00:00

abstract：:The cardioprotective effect of Prunella vulgaris ethylacetate fraction (PVEF) and its constituent rosmarinic acid (RA) was evaluated on isolated rat cardiomyocytes subjected to doxorubicin-induced oxidative stress. The cytoprotectivities of PVEF and RA were concentration-dependent in the range of 0.005 to 0.05 mg/ml a...

journal_title：Fitoterapia

authors： Psotová J,Chlopcíková S,Miketová P,Simánek V

更新日期：2005-09-01 00:00:00

abstract：:Cassia occidentalis L. is an annual or perennial Ayurvedic plant which is used in several traditional medicines to cure various diseases. This weed has been known to possess antibacterial, antifungal, antidiabetic, anti-inflammatory, anticancerous, antimutagenic and hepatoprotective activity. A wide range of chemical ...

journal_title：Fitoterapia

authors： Yadav JP,Arya V,Yadav S,Panghal M,Kumar S,Dhankhar S

更新日期：2010-06-01 00:00:00

abstract：:Four new naphthylisoquinoline alkaloids, the 5,8'-coupled ancistroyafungines A-C (1-3) and the 5,1'-linked ancistroyafungine D (4), have been isolated from the stem bark of an as yet unidentified Ancistrocladus (Ancistrocladaceae) liana recently discovered near the village Yafunga, in the North-Central region of the D...

journal_title：Fitoterapia

authors： Kavatsurwa SM,Lombe BK,Feineis D,Dibwe DF,Maharaj V,Awale S,Bringmann G

更新日期：2018-10-01 00:00:00

abstract：:Biomass and secondary metabolite accumulation were assayed on a wide range of auxins, cytokinins and their combinations using Ecballium elaterium callus tissue. The best combination was that consisting of alpha-naphthalene acetic acid (NAA) and benzylamino purine (BAP) (1 mg/l of medium, each). NAA and BAP were set up...

journal_title：Fitoterapia

authors： Attard EG,Scicluna-Spiteri A

更新日期：2001-01-01 00:00:00

abstract：:Illicium verum is a well known spice in traditional Indian system for its therapeutic potential. The present study was aimed to evaluate the acetylcholinesterase (AChE) and butyrylcholinesterase inhibitory (BChE) activity of standardized extracts of I. verum and its oil. Present study confirmed that anethole contribut...

journal_title：Fitoterapia

authors： Bhadra S,Mukherjee PK,Kumar NS,Bandyopadhyay A

更新日期：2011-04-01 00:00:00

abstract：:The effect of basil oil on the phagocytic capability and respiratory burst response of mouse peritoneal macrophages was studied. The oil inhibited the phagocytosis of opsonized sheep erythrocytes. This inhibition was both dose- and time-dependent and reverted 24 h after removing the extract from the culture medium. On...

journal_title：Fitoterapia

authors： Courrèges MC,Benencia F

更新日期：2002-08-01 00:00:00

abstract：:The present study investigated the effects of isopulegol, a monoterpene alcohol, in PTZ-induced convulsions and verified possible involved mechanisms. Saline, isopulegol or diazepam were intraperitonealy injected 30 min before PTZ. The latency for development of convulsions and mortality, as well as the mortality prot...

journal_title：Fitoterapia

authors： Silva MI,Silva MA,de Aquino Neto MR,Moura BA,de Sousa HL,de Lavor EP,de Vasconcelos PF,Macêdo DS,de Sousa DP,Vasconcelos SM,de Sousa FC

更新日期：2009-12-01 00:00:00

abstract：:Phytochemical studies on the ethanol extract of the aerial parts of Ecdysanthera rosea led to the isolation of three new compounds, hydroquinone diglycoside acyl esters, ecdysanrosin A (1) and sesquiterpene, 5β-hydroperoxycostic acid (2) and apocarotenoid, 2, 4, 7-trimethyl-2, 4, 6, 8-tetraene-dialdehyde (3). Their st...

journal_title：Fitoterapia

authors： Zhu X,Zhang Q,Kong L,Wang F,Luo S

更新日期：2010-10-01 00:00:00

abstract：:Thuja occidentalis L. is indigenous for Northern America and commonly cultivated in Europe. Raw materials obtained from this tree are widely applied in the ethnomedicine and phytotherapy of numerous ailments, incl. scurvy, cystitis, rheumatism and cancer. Despite wide medicinal applications of Thuja occidentalis, stil...

journal_title：Fitoterapia

authors： Pudełek M,Catapano J,Kochanowski P,Mrowiec K,Janik-Olchawa N,Czyż J,Ryszawy D

更新日期：2019-04-01 00:00:00

abstract：:Calcium-activated chloride channels (CaCCs) as a kind of widely expressed ion channels play crucial roles in a variety of physiological regulation. TMEM16A has been identified as the molecular basis of CaCCs in numerous cell types and is considered a new drug target for many diseases. Regulating the function of TMEM16...

journal_title：Fitoterapia

authors： Zhu X,Zhang W,Jin L,Zhang G,Yang H,Yu B

更新日期：2020-11-01 00:00:00

abstract：:Diabetes is a worldwide healthy concern, which affects approximately 9% of the population. Tetrahydrocurcumin (THC) is the main metabolite of curcumin, which exerts the anti-diabetic activity. However, the underlying mechanism has not been clarified. In the research, we investigated whether THC could improve diabetes ...

journal_title：Fitoterapia

authors： Yuan T,Yin Z,Yan Z,Hao Q,Zeng J,Li L,Zhao J

更新日期：2020-10-01 00:00:00

abstract：:Callus and differentiated shoots initiated from Solanum tuberosum L. on MS media containing BA, IAA, and Kin. Glycoalkaloids are produced in callus and shoots in concentrations higher than original tubers using HPLC. Callus methanolic extract had promising anticancer activity with low IC(50) values against human carci...

journal_title：Fitoterapia

authors： Al-Ashaal HA

更新日期：2010-09-01 00:00:00

abstract：:Aqueous extract of the stem bark of Mangifera indica and ethanolic extract of the roots of Pluchea ovalis has been studied on rat tracheal smooth muscle in vitro. The extract of M. indica at 1, 2 and 4 mg/ml and that of P. ovalis at 0.25, 0.5 and 1 mg/ml relaxed, dose-dependently, the rat tracheal smooth muscle strip ...

journal_title：Fitoterapia

authors： Agbonon A,Eklu-Gadegbeku K,Aklikokou K,Essien K,Akpagana K,Gbeassor M

更新日期：2002-12-01 00:00:00

abstract：:Four new terpenoids, nemoralisins D-G (1-4), were isolated from the leaves and stems of Aphanamixis grandifolia, along with two known diterpenoids, nemoralisin C and nemoralisin. Among them, compound 1 is the first example of norsesquiterpenoid with δ-lactone moiety, and nemoralisins E-G (2-4), are a class of acyclic ...

journal_title：Fitoterapia

authors： Zhang R,He HP,Di YT,Li SL,Zuo GY,Zhang Y,Hao XJ

更新日期：2014-01-01 00:00:00

abstract：:Five new carboxymethyl flavonoids named 5-carboxymethyl-3', 4', 7-trihydroxyflavone (1), (2S)- 5-carboxymethyl-3', 4', 7-trihydroxyflavonone (2a), (2R)-5-carboxymethyl-3', 4', 7-trihydroxyflavonone (2b), (2S)-5-carboxymethyl-4', 7-dihydroxyflavonone (3), 5- carbomethoxymethyl-4', 7-dihydroxyflavone (4), and a new chro...

journal_title：Fitoterapia

authors： Zou Z,Xu P,Wu C,Zhu W,Zhu G,He X,Zhang G,Hu J,Liu S,Zeng W,Xu K,Tan G

更新日期：2016-06-01 00:00:00

abstract：:Bergenin, a major constituent of Caesalpinia digyna Rottler (Leguminosae) was isolated from its roots and was characterized by comparing its melting point and spectroscopic data (IR, (1)H, (13)C, Mass Spectra) with standard bergenin. Isolated bergenin was then evaluated for antidiabetic (Type 2) activity in streptozot...

journal_title：Fitoterapia

authors： Kumar R,Patel DK,Prasad SK,Laloo D,Krishnamurthy S,Hemalatha S

更新日期：2012-03-01 00:00:00

abstract：:Nagilactones are norditerpene dilactones isolated from the root bark of Podocarpus nagi. Although nagilactone E has been reported to show antifungal activities, its activity is weaker than that of antifungals on the market. Nagilactone E enhances the antifungal activity of phenylpropanoids such as anethole and isosafr...

journal_title：Fitoterapia

authors： Hayashi K,Yamaguchi Y,Ogita A,Tanaka T,Kubo I,Fujita KI

更新日期：2018-07-01 00:00:00

abstract：:A new coumestan, 1,3,9-trihydroxy-8-methoxycoumestan, named flemicoumestan A 1 together with nine isoflavone-related compounds were isolated from the ethyl acetate extract of the roots of Flemingia philippinensis. Their structures were elucidated and confirmed by spectroscopic methods and literature data. Compounds 3 ...

journal_title：Fitoterapia

authors： Li L,Deng X,Zhang L,Shu P,Qin M

更新日期：2011-06-01 00:00:00

abstract：:The antioxidant activity of Citrus paradisi (grapefruit) seeds glyceric extract dissolved in ethanol and in aqueous media was evaluated using three different methods: evaluation by DPPH assay, by 5-lipoxygenase assay and by luminol/xanthine/xanthine oxidase chemiluminescence assay. The total phenolic content was deter...

journal_title：Fitoterapia

authors： Giamperi L,Fraternale D,Bucchini A,Ricci D

更新日期：2004-03-01 00:00:00

abstract：:Two new alkaloidal metabolites, cordytakaoamides A (1) and B (2), as well as, 2-[(2-hydroxyethyl) amino] benzoic acid (3) and 2E-decenamide (4), and three known compounds (5-7) were isolated from ethyl acetate and n-butanol soluble portions of the entomopathogenic fungus, Cordyceps takaomontana NBRC 101754. Compounds ...

journal_title：Fitoterapia

authors： Hama M,Elshamy AI,Yoneyama T,Kasai Y,Yamamoto H,Tanigawa K,Oshiro A,Noji M,Ban S,Imagawa H,Umeyama A

更新日期：2019-11-01 00:00:00

abstract：:It has been reported that icariin and icariside II, two flavonoid glycosides coming from herba epimedii, which have a closely structural relationship, show some pharmacological effects such as preventing osteoporosis, cancer and depression. The content of natural icariside II is very low in herba epimedii, but it is t...

journal_title：Fitoterapia

authors： Xia Q,Xu D,Huang Z,Liu J,Wang X,Wang X,Liu S

更新日期：2010-07-01 00:00:00

abstract：:Lanaroflavone (1), a biflavonoid isolated from the methanol extract of the aerial part of Campnosperma panamense by bioguided fractionation, has been assessed for in vitro antiprotozoal activity. Lanaroflavone showed both antimalarial and leishmanicidal activities, but was inactive against Chagas disease vector, Trypa...

journal_title：Fitoterapia

authors： Weniger B,Vonthron-Sénécheau C,Arango GJ,Kaiser M,Brun R,Anton R

更新日期：2004-12-01 00:00:00

abstract：:Two new guaiane-type sesquiterpenoids containing an interesting epoxy unit, daucuside (1) and daucusol (2) were isolated from the fruits of Daucus carota L. Their chemical structures were elucidated on the basis of MS, NMR spectroscopic analyses coupled with chemical degradation and they were also evaluated for the cy...

journal_title：Fitoterapia

authors： Fu HW,Zhang L,Yi T,Feng YL,Tian JK

更新日期：2010-07-01 00:00:00

abstract：:A new triterpene glycoside (1) along with the known intercedenside B (2) was isolated from the sea cucumber Pseudocolochirus violaceus. Glycoside 1 was elucidated as 3-O-{6-O-sodiumsulfate-3-O-methyl-beta-D-glucopyranosyl-(1-->3)-beta-D-xylopyranosyl-(1-->4)-[beta-D-xylopyranosyl(1-->2)]-beta-D-quinovopyranosyl-(1-->2...

journal_title：Fitoterapia

authors： Zhang SY,Tang HF,Yi YH

更新日期：2007-06-01 00:00:00

abstract：:Two new isocoumarins (1 and 2), a new alkaloid (3), and a known N-acetyldopamine dimer (4) were isolated from the ethyl acetate extract of Chinese insect medicine Eupolyphaga sinensis. Their structures were elucidated on the basis of detailed spectroscopic investigations, such as 1D- and 2D NMR spectroscopy, as well a...

journal_title：Fitoterapia

authors： Jiang HL,Luo XH,Wang XZ,Yang JL,Yao XJ,Crews P,Valeriote FA,Wu QX

更新日期：2012-10-01 00:00:00

abstract：:Two new alkaloids were isolated from the bark of Sarcomelicope megistophylla. Cyclomegistine B (1), a new quinolone alkaloid, that possesses a rare cyclobuta[b]quinoline ring system and sarcomejine B (2) which is a quinolone alkaloid with an unusual side chain. The structure of both compounds was elucidated on the bas...

journal_title：Fitoterapia

authors： Mitaku S,Fokialakis N,Magiatis P,Tillequin F

更新日期：2007-02-01 00:00:00

abstract：:Five new 8-9' linked neolignans conchigeranals A-E (1-5), together with three known compounds galanganal (6), galanganols A (7) and B (8), were isolated from the whole plant of Alpinia conchigera. Their structures were established by spectroscopic analysis, including 2D-NMR spectroscopic techniques. Cytotoxicities of ...

journal_title：Fitoterapia

authors： Xu JJ,Zeng GZ,Yang SC,Shen Y,Tan NH

更新日期：2013-12-01 00:00:00