Abstract:
:The cardioprotective effect of Prunella vulgaris ethylacetate fraction (PVEF) and its constituent rosmarinic acid (RA) was evaluated on isolated rat cardiomyocytes subjected to doxorubicin-induced oxidative stress. The cytoprotectivities of PVEF and RA were concentration-dependent in the range of 0.005 to 0.05 mg/ml and the effect of PVEF correlated with the RA content. Dexrazoxan (DE), used as positive control, was less effective than PVEF or RA.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Psotová J,Chlopcíková S,Miketová P,Simánek Vdoi
10.1016/j.fitote.2005.04.019keywords:
subject
Has Abstractpub_date
2005-09-01 00:00:00pages
556-61issue
6eissn
0367-326Xissn
1873-6971pii
S0367-326X(05)00112-7journal_volume
76pub_type
杂志文章相关文献
FITOTERAPIA文献大全abstract::Panax ginseng is an indigenous medicinal herb and has traditionally been used among Asian population for relief of many human ailments. We investigated the prophylactic role of Korean P. ginseng extract (KG) against X-ray irradiation-induced emesis in an acute rat pica model. Rats were treated with KG (12.5, 25, 50 mg...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.04.008
更新日期:2012-09-01 00:00:00
abstract::The fruit rind of Garcinia gummi-gutta, commonly known as Garcinia cambogia (syn.), is extensively used traditionally as a flavourant in fish curries due to its sharp sour taste. Additional ethnobotanical uses include its use as a digestive and a traditional remedy to treat bowel complaints, intestinal parasites and r...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2015.02.012
更新日期:2015-04-01 00:00:00
abstract::Cyperenoic acid (1) is one of the major sesquiterpenes isolated from Croton crassifolius, which exhibited potent anti-angiogenic activity. Traditional structural modification of 1 is difficult to perform by chemical technology due to the remarkable stability of the patchoulane skeleton. In order to overcome chemical s...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2017.02.004
更新日期:2017-04-01 00:00:00
abstract::Ten new highly oxygenated lanostane triterpenoids, stereinones A-J (1-10), were isolated from the fruiting bodies of the basidiomycete Stereum sp. Compounds 3 and 4 are structurally characterized as intact lanostane-type triterpenoids containing unusual 1,2-diketone functionality at C-11 and C-12, while compound 10 is...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2017.11.020
更新日期:2018-03-01 00:00:00
abstract::6,7-Dimethylesculetin (D), geniposide (G) and rhein (R) are the three major active ingredients of Yin-Chen-Hao-Tang (YCHT), a famous Chinese herbal formula, which has been shown to be clinically effective for treating hepatic injury (HI) syndrome. The present study was conducted to investigate the therapeutic and syne...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2011.07.014
更新日期:2011-12-01 00:00:00
abstract::Piper laetispicum C.DC. (Piperaceae), is an endemic climbing, glabrous plant distributed in the southern part of China. A novel alkaloid amide, Laetispicine, from it has been proven to possess antidepressant activity. In this present study, antidepressant and antinociceptive effects of the ethyl acetate extract (EAE) ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2011.07.006
更新日期:2011-10-01 00:00:00
abstract::A new steroidal alkaloid, (-)-veranigrine (1) was isolated from the roots and rhizomes of Veratrum nigrum L. By means of spectroscopic methods its structure was established as (20S, 25S)-iminocholesta-5,22(N)-diene-1beta,3beta-diol. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2008.09.003
更新日期:2009-01-01 00:00:00
abstract::The crude methanolic extracts of the leaves, stem bark, stem heart wood, root bark and root heart wood of Euroschinus papuanus and the fractions obtained on partitioning with petrol, dichloromethane (D), ethyl acetate (E) and butanol (B), exhibited a broad spectrum antibacterial activity. Fractionation drastically enh...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2004.03.002
更新日期:2004-06-01 00:00:00
abstract::The effect of Cyclovirobuxine D, an active ingredient from Buxus microphylla, was investigated in the potential prevention of cardiac dysfunction in rats with congestive heart failure. Heart failure was induced by left coronary artery occlusion and verified using echocardiography. Cyclovirobuxine D was administered fo...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2011.04.016
更新日期:2011-09-01 00:00:00
abstract::Goldenseal (Hydrastis canadensis) has emerged as one of the top five herbal supplements in the world-wide market. A convenient method for the determination of the quality and possible adulteration of goldenseal products is thin-layer chromatography (TLC). TLC analysis of 10 goldenseal samples using two solvent systems...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(99)00162-8
更新日期:2000-06-01 00:00:00
abstract::Seven new lignan glycosides (1-3, 8-10, and 14) and 17 known compounds were isolated from the branches of Alangium kurzii Craib var. laxifolium. Their structures were established by spectroscopic analysis and circular dichroism (CD) and X-ray analysis. The isolated compounds were evaluated for their antibacterial acti...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2017.07.009
更新日期:2017-09-01 00:00:00
abstract::8,2'-Diprenylquercetin 3-methyl ether, a natural product with prominent anti-breast cancer activity, is the main active constituent of Sinopodophylli Fructus. A high-performance liquid chromatography with a diode array detector coupled with electrospray ionization ion trap time-of-flight multistage mass spectrometry (...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2019.104191
更新日期:2019-09-01 00:00:00
abstract::Epiberberine, a natural protoberberine from Coptis chinensis Franch., is a potential alkaloid for the treatment of a variety of chronic diseases. The aim of this study is to summarize recent advances in the multiple and potential therapeutic effects of epiberberine. High-quality researches published in last two decade...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2020.104771
更新日期:2020-11-01 00:00:00
abstract::Human carboxylesterase 1 (CES1), primarily expressed in the liver and adipocytes, is responsible for the hydrolysis of endogenous esters (such as cholesteryl esters and triacylglycerols) and the metabolism of xenobiotic esters (such as clopidogrel and oseltamivir), thus participates in physiological and pathological p...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2019.104199
更新日期:2019-09-01 00:00:00
abstract::Four new terpenoids, nemoralisins D-G (1-4), were isolated from the leaves and stems of Aphanamixis grandifolia, along with two known diterpenoids, nemoralisin C and nemoralisin. Among them, compound 1 is the first example of norsesquiterpenoid with δ-lactone moiety, and nemoralisins E-G (2-4), are a class of acyclic ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.10.014
更新日期:2014-01-01 00:00:00
abstract::This manuscript reports on the first CE-method suitable for analyzing twelve pharmacologically relevant compounds (flavonoids, caffeic acids and leontopodic acid) in the aerial parts of Leontopodium alpinum. By using a 60mM borax buffer containing 25mM SDS and 35% acetonitrile the analytes could be well resolved in 25...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.09.023
更新日期:2012-12-01 00:00:00
abstract::20(R)-25-hydroxyprotopanaxadiol (25-OH-PPD) is a natural compound showing a variety of anti-tumor effects. In an attempt to search for a new anti-cancer compound with higher antitumor activities, we designed and synthesized a series of 25-OH-PPD derivatives. Cytotoxicity assay of these derivatives towards MCF-7, A549,...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2019.104279
更新日期:2019-09-01 00:00:00
abstract::The crude ethanol extract from the leaves of Zanthoxylum liebmannianum exhibited inhibitory effect on the reproduction of trophozoites of Entamoeba histolytica (IC(50)=3.48 microg/ml) and Giardia lamblia (IC(50)=58.00 microg/ml). From this extract, asarinin, hyperin, beta-sitosterol, and beta-sitosterol glucoside were...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(00)00297-5
更新日期:2001-03-01 00:00:00
abstract::The isolation of 14 known triterpenoids and phytosterols from the trunk bark of Maquira coriacea, and complete spectral data of a cardenolide, k-strophanthin-beta (1), are reported. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(01)00317-3
更新日期:2001-11-01 00:00:00
abstract::Extracts of Lantana camara var. aculeata leaves were studied for their phytochemical constituents and termiticidal effects against adult termite workers. The 5% chloroform extract was found to be significantly effective against termite workers. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2006.05.014
更新日期:2006-09-01 00:00:00
abstract::Three new xanthones, cylindroxanthones A-C (1-3), were isolated from the stem bark of Garcinia cylindrocarpa. The structures were established on the basis of spectroscopic analysis. The molecular structure of 1 was unequivocally confirmed by single-crystal X-ray diffraction analysis. These three xanthones were evaluat...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.11.017
更新日期:2016-01-01 00:00:00
abstract::The alkaloidic fraction of the methanol extract of Peganum harmala seeds was tested in vitro on three tumoral cell-lines: UCP-Med and Med-mek carcinoma, and UCP-Med sarcoma. Proliferation was significantly reduced at all tested concentrations (20-120 micrograms/ml) during the first 24 h of contact. A cell lysis effect...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(99)00117-3
更新日期:2000-02-01 00:00:00
abstract::Bioassay-guided fractionation of the dichloromethane extract of the fungus Neofusicoccum austral SYSU-SKS024 led to the isolation of three new ethylnaphthoquinone derivatives, neofusnaphthoquinone A (1), 6-(1-methoxylethy1)-2,7-dimethoxyjuglone (2), (3R,4R)-3-methoxyl-botryosphaerone D (6), together with six known ana...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2018.01.014
更新日期:2018-03-01 00:00:00
abstract::Ten new tricyclic prezizaane types sesquiterpenoids (1-10) were isolated from ethyl ether extract of agarwood originated from Aquilaria sp. Their structures were unambiguously elucidated on the basis of 1D and 2D NMR spectra as well as by HRESIMS data. The absolute configuration of the new prezizaenes 1, 2 and 4 was d...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2019.104301
更新日期:2019-10-01 00:00:00
abstract::Silymarin, a standardised extract of Silybum marianum (milk thistle), comprises mainly of silybin, with dehydrosilybin (DHSB), quercetin, taxifolin, silychristin and a number of other compounds which are known to possess a range of salutary effects. Indeed, there is evidence for their role in reducing tumour growth, p...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2014.05.016
更新日期:2014-09-01 00:00:00
abstract::Three new xanthones, oblongixanthone F-H (1-3), along with eight known xanthones (4-11), were isolated from an EtOAc extract of the twigs of Garcinia oblongifolia. Their structures were elucidated by spectroscopic analysis including 1D- and 2D-NMR spectroscopy and mass spectrometry. The antidiabetic effects of all iso...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2017.03.003
更新日期:2017-04-01 00:00:00
abstract::Two new minor cyclopeptides, named japonicin A (1), japonicin B (2), were isolated from the whole plants of Sagina japonica (Caryophyllaceae). Their structures were determined as cyclo-(Pro(1)-Pro(2)-Leu(2)-Leu(1)-Phe(2)-Pro(3)-Gly-Ser-Phe(1)) (1) and cyclo-(Pro(1)-Ile-Tyr-Asp-Pro(2)-Phe(2)-Pro(3)-Phe(1)) (2) on the b...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2009.01.004
更新日期:2009-04-01 00:00:00
abstract::Salvianolic acid B (Sal B) is the most abundant phenolic compound in Salvia miltiorrhiza, which has been widely used for the treatment of cardiovascular diseases in Oriental medicine. To elucidate structure of the converted compounds of Sal B by decoction in aqueous solution, Sal B (200 mg) was decocted in an aqueous ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.06.015
更新日期:2012-10-01 00:00:00
abstract::Four new sesquiterpenoids, phellinignins A-D (1-4), together with four known ones (5-8), were isolated from cultures of the fungus Phellinus igniarius. The structures were established by extensive spectroscopic methods including MS, NMR, and the single crystal X-ray diffraction. Compounds 1-3 and 5-8 are tremulane ses...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2019.104415
更新日期:2020-01-01 00:00:00
abstract::Reinvestigation of Onopordon ambiguum extract afforded a new eudesmane derivative 1, in addition to the known elemanoid derivative 2. The structures of both compounds were determined by spectroscopic techniques, including 1H-, 13C-NMR, DEPT, 1H-1H and 1H-13C COSY analysis. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(01)00366-5
更新日期:2002-02-01 00:00:00