Abstract:
:Three new xanthones, cylindroxanthones A-C (1-3), were isolated from the stem bark of Garcinia cylindrocarpa. The structures were established on the basis of spectroscopic analysis. The molecular structure of 1 was unequivocally confirmed by single-crystal X-ray diffraction analysis. These three xanthones were evaluated regarding their cytotoxicity against KB, HeLa S-3, HT-29, MCF-7, and Hep G2 cancer cell lines. Compound 1 exhibited good cytotoxicity against KB cell with IC50 value of 2.36 μM.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Sukandar ER,Ersam T,Fatmawati S,Siripong P,Aree T,Tip-pyang Sdoi
10.1016/j.fitote.2015.11.017subject
Has Abstractpub_date
2016-01-01 00:00:00pages
62-5eissn
0367-326Xissn
1873-6971pii
S0367-326X(15)30123-4journal_volume
108pub_type
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