Essential oil of Lindera neesiana fruit: chemical analysis and its potential use in topical applications.

abstract：:This investigation focuses on the in vitro neuroactive properties of pinostrobin, a substituted flavanone from Cajanus cajan (L.) Millsp. of the Fabaceae family. We demonstrate that pinostrobin inhibits voltage-gated sodium channels of mammalian brain (IC(50)=23 µM) based on the ability of this substance to suppress t...

journal_title：Fitoterapia

authors： Nicholson RA,David LS,Pan RL,Liu XM

更新日期：2010-10-01 00:00:00

abstract：:Three novel xanthonolignoid C-glycosides, glomexanthones A-C, with a trans-dihydrobenzofuran on B ring and a 2-hydroxymethyl-5-hydroxyl-2-pentenoic acid moiety in the sugar chain were isolated from an ethanol extract of Polygala glomerata. Their structures and absolute configurations were characterized by extensive NM...

journal_title：Fitoterapia

authors： Li CJ,Yang JZ,Yu SS,Zhao CY,Peng Y,Wang XL,Zhang DM

更新日期：2014-03-01 00:00:00

abstract：:The aim of the present research was to establish a comprehensive strategy to identify the metabolites of isoimperatorin after biotransformation with rat liver microsomes in vitro, and further describe metabolic kinetic characteristics of isoimperatorin and its main metabolites. Utilizing liquid chromatography with tim...

journal_title：Fitoterapia

authors： Chen TL,Zhang YB,Xu W,Kang TG,Yang XW

更新日期：2014-03-01 00:00:00

abstract：:Aqueous extract of Pteris multifida showed scavenging activities on DPPH, hydroxyl radicals and reducing power. ...

journal_title：Fitoterapia

authors： Wang TC,Ti MC,Lo SC,Yang CC

更新日期：2007-04-01 00:00:00

abstract：:A new guanidine alkaloid, millaurine A (1), was isolated from the methanol extract of the seeds of Millettia laurentii. The structure of the new compound was elucidated on the basis of spectral analysis. ...

journal_title：Fitoterapia

authors： Ngamga D,Fanso Free SN,Tane P,Fomum ZT

更新日期：2007-04-01 00:00:00

abstract：:Australian native plants have a long history of therapeutic use in indigenous cultures, however, they have been poorly studied scientifically. We analysed the effects of 14 plant derived compounds from the species Pilidiostigma glabrum, Myoporum montanum, Geijera parviflora, and Rhodomyrtus psidioides for their potent...

journal_title：Fitoterapia

authors： Adams DH,Shou Q,Wohlmuth H,Cowin AJ

更新日期：2016-03-01 00:00:00

abstract：:Bakuchicin is a furanocoumarin isolated from the seeds of Psoralea corylifolia, which is used in oriental medicine. However, limited information on the pharmacokinetics of bakuchicin is available and in addition, no determined method has been devised to quantify bakuchicin levels in the plasma. In the present study, w...

journal_title：Fitoterapia

authors： Jo JH,Kim JH,Lee HS,Jeong GS,Lee JM,Lee S

更新日期：2017-07-01 00:00:00

abstract：:Alkaloids comprise one of the largest groups of plant secondary metabolites including vinca alkaloids. The ability of six alkaloids from Veratrum lobelianum, one from Veratrum nigrum and three from Peganum nigellastrum to modify transport activity of MDR1 was studied. Flow-cytometry in a multidrug-resistant human MDR1...

journal_title：Fitoterapia

authors： Ivanova A,Serly J,Christov V,Stamboliyska B,Molnar J

更新日期：2011-06-01 00:00:00

abstract：:The essential oil from the aerial parts of Seseli annuum, wild-growing in Serbia, was obtained by hydrodistillation and analyzed using GC and GC/MS. A total of 43 components were identified representing 96.5% of S. annuum oil. The most abundant compounds were germacrene D (29.8%), sabinene (10.3%), beta-ocimene Z (9.8...

journal_title：Fitoterapia

authors： Milosavljević S,Tesević V,Vucković I,Jadranin M,Vajs V,Soković M,Janaćković P,Jovanović A

更新日期：2007-06-01 00:00:00

abstract：:Traditional Indonesian medicinal plants were screened for their inhibitory effects on the nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages and for the antioxidant activity through the evaluation of free radical scavenging effect and reducing power. The results of screening indic...

journal_title：Fitoterapia

authors： Choi EM,Hwang JK

更新日期：2005-03-01 00:00:00

abstract：:Phytochemical investigation on the stem bark of Toona sinensis was carried out by various chromatographic techniques resulting in the isolation and elucidation of two novel tirucallane triterpenoids, named (20S)-3-oxo-tirucalla-25-nor-7-en-24-oic acid (1) and (20S)-5α,8α-epidioxy-3-oxo-24-nor-6.9(11)-dien-23-oic acid ...

journal_title：Fitoterapia

authors： Tang J,Xu J,Zhang J,Liu WY,Xie N,Chen L,Feng F,Qu W

更新日期：2016-07-01 00:00:00

abstract：:Extracts of the leaves of Securinega leucopyrus exhibited a broad spectrum of antimicrobial activity. ...

journal_title：Fitoterapia

authors： Bakshu LM,Jeevan Ram A,Venkata Raju R

更新日期：2001-12-01 00:00:00

abstract：:Total sennosides concentration is a very important factor when rhubarb and senna will be used as crude drugs. However, one-step analytical technique for total sennosides has not been reported except HPLC. An enzyme-linked immunosorbent assay (ELISA) for total sennosides concentration by using the combination of anti-s...

journal_title：Fitoterapia

authors： Morinaga O,Uto T,Sakamoto S,Tanaka H,Shoyama Y

更新日期：2009-01-01 00:00:00

abstract：:Fourteen pregnane-type steroidal alkaloids were isolated from the ethanolic extracts of whole Sarcococca hookeriana var. digyna plants. Their structures were elucidated on the basis of spectral data. Three of them were identified as new steroidal alkaloids: (S)-20-(N,N-dimethylamino)-16α,17α-epoxy-3β-methoxy-pregn-5-e...

journal_title：Fitoterapia

authors： Zhang PZ,Wang F,Yang LJ,Zhang GL

更新日期：2013-09-01 00:00:00

abstract：:Two new guaiane-type sesquiterpenoids containing an interesting epoxy unit, daucuside (1) and daucusol (2) were isolated from the fruits of Daucus carota L. Their chemical structures were elucidated on the basis of MS, NMR spectroscopic analyses coupled with chemical degradation and they were also evaluated for the cy...

journal_title：Fitoterapia

authors： Fu HW,Zhang L,Yi T,Feng YL,Tian JK

更新日期：2010-07-01 00:00:00

abstract：:Two new pentacyclic triterpenes named kirmanoic acid (1) and kurramanoic acid (2) have been isolated from the chloroform-soluble portion of the whole plant of Nepeta clarkei Hook. The structures of the two new compounds were assigned on the basis of their ¹H and ¹³C NMR spectra including two-dimensional NMR techniques...

journal_title：Fitoterapia

authors： Hussain J,Ur Rehman N,Hussain H,Al-Harrasi A,Ali L,Rizvi TS,Ahmad M,Mehjabeen

更新日期：2012-04-01 00:00:00

abstract：:Dichloromethane extract of propolis (DCME) originating from Pitcairn Island demonstrated potent cytotoxicity against triple-negative MDA-MB-231 human breast carcinoma cells. The results from MTT assay showed that DCME inhibits the growth of the cancer cells in a dose- and time-dependent manner and upon the cell growth...

journal_title：Fitoterapia

authors： Georgieva K,Trusheva B,Uzunova V,Stoyanova T,Valcheva V,Popova M,Tzoneva R,Bankova V

更新日期：2018-07-01 00:00:00

abstract：:A sensitive and specific HPLC method was developed to analyze baicalin in rat plasma. The author had compared the pharmacokinetics of baicalin after oral administration of HLJDT decoction or pure baicalin in MCAO and sham-operated rats. All the rats were divided into two groups, MCAO and sham-operated rats. Each group...

journal_title：Fitoterapia

authors： Zeng MF,Pan LM,Zhu HX,Zhang QC,Guo LW

更新日期：2010-09-01 00:00:00

abstract：:One new Euphane-type triterpenoid 3β-hydroxytirucalla-5, 24-dien-21-oic acid (1), and ten known compounds (2-11) were isolated from Melia azedarach L. through bioassay-guided chemical analysis. The structures of the isolated compounds were established by means of 1D and 2D NMR spectroscopic ((1)H, (13)C, DEPT, COSY, H...

journal_title：Fitoterapia

authors： Khan MF,Rawat AK,Pawar B,Gautam S,Srivastava AK,Negi DS

更新日期：2014-10-01 00:00:00

abstract：:A series of 33 curcumin analogues was synthesized and tested on TRPA1, TRPM8, and TRPV1 channels. Twenty of them acted as good modulators of TRPA1 channels. None was able to significantly activate TRPM8 channels, while curcumin itself and six curcuminoids belonging to the 1,3-dicarbonyl and acyclic series behaved as '...

journal_title：Fitoterapia

authors： Nalli M,Ortar G,Schiano Moriello A,Di Marzo V,De Petrocellis L

更新日期：2017-10-01 00:00:00

abstract：:Nagilactones are norditerpene dilactones isolated from the root bark of Podocarpus nagi. Although nagilactone E has been reported to show antifungal activities, its activity is weaker than that of antifungals on the market. Nagilactone E enhances the antifungal activity of phenylpropanoids such as anethole and isosafr...

journal_title：Fitoterapia

authors： Hayashi K,Yamaguchi Y,Ogita A,Tanaka T,Kubo I,Fujita KI

更新日期：2018-07-01 00:00:00

abstract：:A total of 58 fungal isolates, belonging to 24 genera, were obtained from the leaves, stems and roots of Ginkgo biloba L.. Among them, one endophytic fungal strain, Penicillium cataractum SYPF 7131, displayed the strongest antibacterial activity. Four new compounds (1-4) were isolated from the strain fermentation brot...

journal_title：Fitoterapia

authors： Wu YY,Zhang TY,Zhang MY,Cheng J,Zhang YX

更新日期：2018-07-01 00:00:00

abstract：:A new sulfur-containing iridoid glucoside, named paederoside B, was isolated from the stems of Paederia scandens. The structure of the new compound was elucidated as paederosidyl paederosidate by spectral evidence. ...

journal_title：Fitoterapia

authors： Zou X,Peng S,Liu X,Bai B,Ding L

更新日期：2006-07-01 00:00:00

abstract：:A series of new Lycopodium alkaloids, namely 1-epi-malycorin A (1), 1-epi-17S-hydroxymalycorin A (2), 6α-hydroxyphlegmariurine A (3), 2S,4R-dihydroxyfawcettimine (4), and 16-hydroxylycodine (5), together with 24 known ones, have been isolated from the club moss Phlegmariurus henryi. The structures of the new compounds...

journal_title：Fitoterapia

authors： Liu YC,Su J,Wu XD,Zhang ZJ,Fan M,Zhu QF,He J,Li XN,Peng LY,Cheng X,Zhao QS

更新日期：2016-12-01 00:00:00

abstract：:Five new megastigmane glycosides, urenalobasides A-E (1-5), together with 11 known ones (6-16) were isolated from Urena lobata. Their structures were determined by extensive spectroscopic and spectrometric data (1D and 2D NMR, IR, and HRESIMS) and calculated electronic circular dichroism method. Compounds 1 and 2 are ...

journal_title：Fitoterapia

authors： Su C,Qi B,Wang J,Ding N,Wu Y,Shi XP,Zhu ZX,Liu X,Wang XH,Zheng J,Tu PF,Shi SP

更新日期：2018-06-01 00:00:00

abstract：:Chemical investigation of the liquid culture of the endophytic fungus Bipolaris sorokiniana A606, which was isolated from the medicinal plant Pogostemon cablin resulted in the isolation of four new cytotoxic compounds, named isocochlioquinones D-E (1-2) and cochlioquinones G-H (3-4), along with five known cochlioquino...

journal_title：Fitoterapia

authors： Wang M,Sun ZH,Chen YC,Liu HX,Li HH,Tan GH,Li SN,Guo XL,Zhang WM

更新日期：2016-04-01 00:00:00

abstract：:European Hawthorn species (Crataegus spp.) are traditionally used for their demonstrated cardioprotective benefits. Most products are based on the compendial leaf and flower drug (LFD), which is standardised on the total flavonoid content (TF). In order to reduce variability associated with the wild plant origin and t...

journal_title：Fitoterapia

authors： Peschel W,Bohr C,Plescher A

更新日期：2008-01-01 00:00:00

abstract：:There is growing evidence that motherwort (Leonurus japonicus Houtt.), and Chinese patent medicines derived from motherwort, alleviate postpartum uterine subinvolution, as well as the effects on myocardial and cerebral ischemic injuries. We hypothesized that these beneficial effects of motherwort may be related to ang...

journal_title：Fitoterapia

authors： He YL,Shi JY,Peng C,Hu LJ,Liu J,Zhou QM,Guo L,Xiong L

更新日期：2018-07-01 00:00:00

abstract：:A different type of biologically active compound from Kuji amber (Late Cretaceous, Japan) before the K-Pg boundary [65 million years ago (Ma)] was isolated based on the growth-restoring activity of a mutant yeast involving Ca2+ signal transduction. It was identified as a spirolactone norditerpenoid, (4R*, 5S*, 8R*, 9R...

journal_title：Fitoterapia

authors： Shimizu E,Koshino H,Noro A,Maruyama M,Shimoda N,Uesugi S,Ohnishi M,Kimura KI

更新日期：2019-04-01 00:00:00

abstract：:The purpose of this study was to determine the photoprotective properties of the methanolic extract of Buddleja scordioides, as well as verbascoside and linarin which were isolated from this extract, and linarin acetate prepared in the laboratory. The photoprotective effect of substances against UV-B induced cellular ...

journal_title：Fitoterapia

authors： Avila Acevedo JG,Castañeda CM,Benitez FJ,Durán DA,Barroso VR,Martínez CG,Muñoz LJ,Martínez CA,Romo de Vivar A

更新日期：2005-06-01 00:00:00