Abstract：
:The first chemical examination of roots of the traditionally used medicinal plant Talinum triangulare (Portulacaceae) from Nigeria led to the isolation of two new C-methylated flavonoids, 5,6-dimethoxy-7-hydroxy-8-methyl-flavone (1), 5,6-dimethoxy-8-methyl-2-phenyl-7H-1-benzopyran-7-one (2), and one new α-pyrone derivative, 4-methoxy-6-(2-hydroxy-4-phenylbutyl)-2H-pyran-2-one (3), along with thirteen known compounds, including nine amides (4-12), indole-3-carboxylic acid (13), p-hydroxy benzoic acid (14), and two steroids (15-16). Their structures were elucidated by extensive spectroscopic measurements including 1D, 2D NMR, MS, and by comparison with the literature. All isolated compounds were screened for their cytotoxic and antifungal activities. However, none of them showed significant activity.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Umeokoli BO,Muharini R,Okoye FB,Ajiwe VI,Akpuaka MU,Lin W,Liu Z,Proksch Pdoi
10.1016/j.fitote.2016.01.002subject
Has Abstractpub_date
2016-03-01 00:00:00pages
169-73eissn
0367-326Xissn
1873-6971pii
S0367-326X(16)30002-8journal_volume
109pub_type
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