The essential oil of Eucalyptus tereticornis, and its constituents alpha- and beta-pinene, potentiate acetylcholine-induced contractions in isolated rat trachea.

Abstract:

:The effects of the essential oil of Eucalyptus tereticornis (EOET), especially the effects of its constituents alpha- and beta-pinene, were studied on rat trachea in vitro. In tracheal rings, EOET, alpha- or beta-pinene potentiated the contractions induced by acetylcholine (ACh). Contractions induced by K(+) (60mM) were also potentiated by alpha- and beta-pinene, but were reduced by EOET. Our findings show that EOET has myorelaxant effects on rat airways, but potentiates ACh-induced contractions. Monoterpenes alpha- and beta-pinene are involved in its potentiating actions, but are not responsible for its myorelaxant effects. A putative inhibition of the acetylcholinesterase enzyme is involved.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Lima FJ,Brito TS,Freire WB,Costa RC,Linhares MI,Sousa FC,Lahlou S,Leal-Cardoso JH,Santos AA,Magalhães PJ

doi

10.1016/j.fitote.2010.03.012

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

649-55

issue

6

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(10)00071-7

journal_volume

81

pub_type

杂志文章
  • Seladoeflavones A-F, six novel flavonoids from Selaginella doederleinii.

    abstract::Six new flavonoids, seladoeflavones A-F (1-6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroi...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2016.11.014

    authors: Zou Z,Xu K,Xu P,Li X,Cheng F,Li J,Yu X,Cao D,Li D,Zeng W,Zhang G,Tan G

    更新日期:2017-01-01 00:00:00

  • Influence of plant origin natural α-pinene with different enantiomeric composition on bacteria, yeasts and fungi.

    abstract::Although the nature-identical chemical compounds are cheaper, they not always repeat biological activity of plant origin natural chemical compounds, often react allergies and resistance of microorganisms. The aim of this study was to investigate effects of Juniperus communis origin α-pinene with different enantiomeric...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2018.04.013

    authors: Ložienė K,Švedienė J,Paškevičius A,Raudonienė V,Sytar O,Kosyan A

    更新日期:2018-06-01 00:00:00

  • New depsidones and xanthone from the roots of Garcinia schomburgkiana.

    abstract::Two new depsidones, schomburgdepsidones A and B (1 and 2), and one new xanthone, schomburgxanthone A (3), together with eight known compounds (4-11) were isolated from the roots of Garcinia schomburgkiana. Their chemical structures were established on the basis of spectroscopic analysis. The in vitro cytotoxicity of a...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2016.04.012

    authors: Sukandar ER,Siripong P,Khumkratok S,Tip-Pyang S

    更新日期:2016-06-01 00:00:00

  • A HPTLC densitometric method for the determination of aloeverose in Aloe vera gel.

    abstract::Aloe vera gel is a familiar ingredient in a range of widely available and advertisement healthcare and cosmetic products. As to date there are no documented reports on the standardization of A. vera gel and the following study is an attempt in this direction. A. vera gel was evaluated for its aloeverose content for th...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2009.09.001

    authors: Lobo R,Prabhu KS,Shirwaikar A,Ballal M,Balachandran C,Shirwaikar A

    更新日期:2010-06-01 00:00:00

  • Antifungal properties of Ocimum gratissimum essential oil (ethyl cinnamate chemotype).

    abstract::Largely widespread in tropical countries, Ocimum gratissimum has been claimed for many uses in folk medicine. Recent research on its essential oils showed five chemotypes. An Indian chemotype, with a high level of ethyl cinnamate, presents, in vitro, an interesting spectrum of antifungal properties. ...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/s0367-326x(00)00206-9

    authors: Dubey NK,Tiwari TN,Mandin D,Andriamboavonjy H,Chaumont JP

    更新日期:2000-09-01 00:00:00

  • A phytochemical investigation of Alchornea latifolia.

    abstract::A phytochemical investigation of the chloroform leaf extract of Alchornea latifolia has been undertaken. Along with the triterpenoids taraxerone, friedelin, epifriedelinol, and taraxerol, the plant also contains seco-3,4-friedelin (dihydroputranjivic acid) (1) and seco-3,4-taraxerone (2). These A-ring-opened triterpen...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/s0367-326x(99)00133-1

    authors: Setzer WN,Shen X,Bates RB,Burns JR,McClure KJ,Zhang P,Moriarity DM,Lawton RO

    更新日期:2000-04-01 00:00:00

  • Transcriptome analysis of Aconitum carmichaelii and exploration of the salsolinol biosynthetic pathway.

    abstract::Aconitum carmichaelii has been used in traditional Chinese medicine for treating various diseases for several thousand years. Based on the biosynthetic pathway of some alkaloids such as C19-diterpenoid alkaloids and obvious differences in alkaloid content between leaves of two A. carmichaelii varieties has been report...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2019.104412

    authors: Yang Y,Hu P,Zhou X,Wu P,Si X,Lu B,Zhu Y,Xia Y

    更新日期:2020-01-01 00:00:00

  • Miscellaneous lanostane triterpenoids with cytotoxicities from fruiting bodies of the basidiomycete Stereum sp.

    abstract::Ten new highly oxygenated lanostane triterpenoids, stereinones A-J (1-10), were isolated from the fruiting bodies of the basidiomycete Stereum sp. Compounds 3 and 4 are structurally characterized as intact lanostane-type triterpenoids containing unusual 1,2-diketone functionality at C-11 and C-12, while compound 10 is...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2017.11.020

    authors: Yao JN,Chen L,Chen HP,Zhao ZZ,Zhang SB,Huang Y,Tang Y,Isaka M,Li ZH,Feng T,Liu JK

    更新日期:2018-03-01 00:00:00

  • Inhibition of hepatitis C virus replication by chalepin and pseudane IX isolated from Ruta angustifolia leaves.

    abstract::Hepatitis C virus (HCV) infection is highly prevalent among global populations, with an estimated number of infected patients being 170 million. Approximately 70-80% of patients acutely infected with HCV will progress to chronic liver disease, such as liver cirrhosis and hepatocellular carcinoma, which is a substantia...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2014.10.011

    authors: Wahyuni TS,Widyawaruyanti A,Lusida MI,Fuad A,Soetjipto,Fuchino H,Kawahara N,Hayashi Y,Aoki C,Hotta H

    更新日期:2014-12-01 00:00:00

  • Genus Alangium - A review on its traditional uses, phytochemistry and pharmacological activities.

    abstract::The species from Alangium have been used as folk medicine to treat rheumatism, skin diseases, diabetes by the people of Southeast Asia. Previous phytochemical studies have shown this genus are rich sources of alkaloids, glycosides, and terpenoids, which have attracted considerable attention of many researchers due to ...

    journal_title:Fitoterapia

    pub_type: 杂志文章,评审

    doi:10.1016/j.fitote.2020.104773

    authors: Hu XY,Wei X,Zhou YQ,Liu XW,Li JX,Zhang W,Wang CB,Zhang LY,Zhou Y

    更新日期:2020-11-01 00:00:00

  • New furoquinoline alkaloids from the leaves of Evodia lepta.

    abstract::Three new furoquinoline alkaloids, leptanoines A-C (1-3) along with three known compounds (4-6) were isolated from the leaves of Evodia lepta. Their structures were identified by interpretation of their spectroscopic data as well as comparison with those reported in the literature. In addition, all isolated compounds ...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2013.12.002

    authors: Sichaem J,Jirasirichote A,Sapasuntikul K,Khumkratok S,Sawasdee P,Do TM,Tip-pyang S

    更新日期:2014-01-01 00:00:00

  • Gastroprotective constituents of Salvia officinalis L.

    abstract::The gastrointestinal activity of hydroalcoholic extract (HE) of Salvia officinalis was evaluated in a model of ethanol-induced gastric lesion. HE showed excellent activity, with ID(50) 84.0 (54.8-128.9) mg/kg. The acetic acid-induced ulcer and the total acidity of the gastric secretion were also reduced by HE, and, in...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2009.05.015

    authors: Mayer B,Baggio CH,Freitas CS,dos Santos AC,Twardowschy A,Horst H,Pizzolatti MG,Micke GA,Heller M,dos Santos EP,Otuki MF,Marques MC

    更新日期:2009-10-01 00:00:00

  • Cinchonicine-derived alkaloids from the bark of the Peruvian Ladenbergia oblongifolia.

    abstract::The isolation of cinchonicine-derived alkaloids epicinchonicinol (1), cinchonidicinol (2) and a mixture of dihydrocinchonicinol and dihydrocinchonidicinol (3) from the dried bark of Ladenbergia oblongifolia, is reported along with (1)H and (13)C-NMR data. ...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/s0367-326x(01)00298-2

    authors: Okunade AL,Lewis WH,Elvin-Lewis MP,Casper SJ,Goldberg DE

    更新日期:2001-08-01 00:00:00

  • Phenylpropanoids and neolignans from Smilax trinervula.

    abstract::A new phenylpropanoid glucoside and two new neolignans, namely (1S, 2R)-1-(3, 4, 5-trimethoxyphenyl)-3-(β-d-glucopyranosyloxy)-1, 2, 3-propanetriol (1), and (7R, 8R)-4, 7, 9, 9'-tetrahydroxy-3, 5, 3', 5'-tetramethoxy-8-4'-oxyneolignan 4-O-β-d-glucopyranoside (2) and 3', 9, 9'-trihydroxy-3, 5-dimethoxy-8-O-4'-neolignan...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2015.05.010

    authors: Shu J,Liang F,Liang J,Liang Y,Li F,Shao F,Liu R,Huang H

    更新日期:2015-07-01 00:00:00

  • Oleanene constituents of Lantana cujabensis.

    abstract::A new compound, 3beta,25-epoxy-3alpha-hydroxy-22beta-isobutanoyloxyolean-12-ene-28-oic acid (1), and two known triterpenoids lantanilic acid (2) and camaric acid (3) were isolated from the stem and leaves of Lantana cujabensis. Their structures were elucidated by spectroscopic methods. The ethanol extracts did not sho...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2004.02.005

    authors: Okunade AL,Lewis WH

    更新日期:2004-06-01 00:00:00

  • Cassia occidentalis L.: a review on its ethnobotany, phytochemical and pharmacological profile.

    abstract::Cassia occidentalis L. is an annual or perennial Ayurvedic plant which is used in several traditional medicines to cure various diseases. This weed has been known to possess antibacterial, antifungal, antidiabetic, anti-inflammatory, anticancerous, antimutagenic and hepatoprotective activity. A wide range of chemical ...

    journal_title:Fitoterapia

    pub_type: 杂志文章,评审

    doi:10.1016/j.fitote.2009.09.008

    authors: Yadav JP,Arya V,Yadav S,Panghal M,Kumar S,Dhankhar S

    更新日期:2010-06-01 00:00:00

  • A potential calcium antagonist and its antihypertensive effects.

    abstract::Imperatorin (Imp) as a hypotensive active ingredient, its hypotensive effect was evaluated in the SHRs, its calcium antagonism and affinity to L-type calcium channel was also confirmed. The results showed that the blood pressure was decreased in the SHRs treated with Imp, the aortic ring was relaxed with Imp, L-type c...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2011.05.016

    authors: Zhang Y,Cao Y,Wang Q,Zheng L,Zhang J,He L

    更新日期:2011-10-01 00:00:00

  • Two new benzofuran derivatives with anti-inflammatory activity from Liriope spicata var. prolifera.

    abstract::Two new benzofuran derivatives, 2-(4'-hydroxybenzyl)-5,6-methylenedioxy-benzofuran (1) and 2-(4'-hydroxybenzoyl)-5,6-methylenedioxy-benzofuran (2), along with 8 known compounds were isolated from 60% EtOH extract of the fibrous roots of Liriope spicata var. prolifera. Their structures were elucidated on the basis of e...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2010.09.002

    authors: Hu ZF,Chen LL,Qi J,Wang YH,Zhang H,Yu BY

    更新日期:2011-03-01 00:00:00

  • High performance liquid chromatographic analysis and anticancer potential of Oplopanax horridus: comparison of stem and berry extracts.

    abstract::Oplopanax horridus or devil's club is a herbal medicine distributed in North America. The constituents and pharmacological activities of O. horridus (OPH) are largely unknown. In this study, we assayed OPH stem and berry extracts using high performance liquid chromatography (HPLC). The anticancer potentials of extract...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2009.08.003

    authors: Wang CZ,Aung HH,Mehendale SR,Shoyama Y,Yuan CS

    更新日期:2010-03-01 00:00:00

  • Oxygenated C17 polyacetylene metabolites from Algerian Eryngium tricuspidatum L. roots: Structure and biological activity.

    abstract::The secondary metabolite pattern of Eryngium tricuspidatum has been found to be dominated by C17 acetylene oxylipins, according to the chemistry reported in the literature for the genus Eryngium. Two new oxylipins, 11-acetoxy-falcarindiol (4) and 1,2-dihydro-11-acetoxy-falcarindiol (5) have been isolated, along with m...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2019.104355

    authors: Djebara A,Ciavatta ML,Mathieu V,Colin M,Bitam F,Carbone M,Gavagnin M

    更新日期:2019-10-01 00:00:00

  • The Goodeniaceae.

    abstract::The Goodeniaceae family contributes some of the more spectacular wildflowers found on the Australian continent. The bright and vibrant colours that characterise members of the family has attracted much horticultural interest. A number of species have traditionally been used for medicinal purposes by indigenous communi...

    journal_title:Fitoterapia

    pub_type: 杂志文章,评审

    doi:10.1016/j.fitote.2004.01.018

    authors: Ghisalberti EL

    更新日期:2004-07-01 00:00:00

  • New steroids and sesquiterpene from Turraea pubescens.

    abstract::Four new compounds, including three new steroids (1-3) and one new sesquiterpene (6), and two new natural products (4-5), as well as three known steroids (7-9) were isolated from the twigs of Turraea pubescens. Compounds 3-5 are C₂₂ steroids isolated from the Meliaceae family for the first time. Their structures were ...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2013.07.006

    authors: Yuan CM,Tang GH,Wang XY,Zhang Y,Cao MM,Li XH,Li Y,Li SL,Di YT,He HP,Hao XJ,Hua HM

    更新日期:2013-10-01 00:00:00

  • Antimicrobial activity of pyrrolizidine alkaloids from Heliotropium subulatum.

    abstract::Five pyrrolizidine alkaloids have been isolated from Heliotropium subulatum and tested for their antimicrobial activity. ...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/s0367-326x(02)00016-3

    authors: Singh B,Sahu PM,Singh S

    更新日期:2002-04-01 00:00:00

  • Antibacterial activity of Eupatorium glandulosum leaves.

    abstract::Antibacterial screening of petroleum ether, chloroform, ethyl acetate, methanol and aqueous extracts of Eupatorium glandulosum leaves exhibited a broad spectrum of inhibitory activity against Gram (+) and Gram (-) pathogenic bacteria. ...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2004.12.001

    authors: Sasikumar JM,Doss AP,Doss A

    更新日期:2005-03-01 00:00:00

  • Silymarin and its constituents in cardiac preconditioning.

    abstract::Silymarin, a standardised extract of Silybum marianum (milk thistle), comprises mainly of silybin, with dehydrosilybin (DHSB), quercetin, taxifolin, silychristin and a number of other compounds which are known to possess a range of salutary effects. Indeed, there is evidence for their role in reducing tumour growth, p...

    journal_title:Fitoterapia

    pub_type: 杂志文章,评审

    doi:10.1016/j.fitote.2014.05.016

    authors: Zholobenko A,Modriansky M

    更新日期:2014-09-01 00:00:00

  • A comprehensive scientific overview of Garcinia cambogia.

    abstract::The fruit rind of Garcinia gummi-gutta, commonly known as Garcinia cambogia (syn.), is extensively used traditionally as a flavourant in fish curries due to its sharp sour taste. Additional ethnobotanical uses include its use as a digestive and a traditional remedy to treat bowel complaints, intestinal parasites and r...

    journal_title:Fitoterapia

    pub_type: 杂志文章,评审

    doi:10.1016/j.fitote.2015.02.012

    authors: Semwal RB,Semwal DK,Vermaak I,Viljoen A

    更新日期:2015-04-01 00:00:00

  • Stimulation of dragon's blood accumulation in Dracaena cambodiana via fungal inoculation.

    abstract::Dragon's blood is a rare and precious traditional medicine used by different cultures since ancient times. However, studies on enhancing the rapid accumulation of dragon's blood in Dracaena cambodiana and determining its formation mechanism are unavailable. In this study, the activities of two fungi, namely, BJDC01 an...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2013.03.012

    authors: Cui JL,Wang CL,Guo SX,Xiao PG,Wang ML

    更新日期:2013-06-01 00:00:00

  • Evaluation of the pharmacodynamics and pharmacokinetics of brucine following transdermal administration.

    abstract::Before the design of brucine-containing transdermal formulations, the pharmacodynamics and pharmacokinetics of brucine following transdermal administration should be evaluated. In this study, the effect of addition of ethanol on solubility of bruicne was investigated and 20% ethanol was added into PBS to obtain 10mg/m...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2013.03.007

    authors: Chen J,Hu W,Qu YQ,Dong J,Gu W,Gao Y,Fang Y,Fang F,Chen ZP,Cai BC

    更新日期:2013-04-01 00:00:00

  • Novel polyprenylated benzophenone derivatives from Clusia burle-marxii.

    abstract::Three new caged polyprenylated benzophenone derivatives named burlemarxiones D-F (1-3) were isolated from the hexane extract of Clusia burle-marxii trunks. Burlemarxione D (1) contains the tetracyclo[8.3.1.03,11.05,10]tetradecane core skeleton also observed for burlemarxione A, its probable immediate precursor. Howeve...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2020.104760

    authors: Ferraz CG,Ribeiro PR,Mendonça R,Silveira ER,Cruz FG

    更新日期:2020-10-16 00:00:00

  • Chemical characteristics of saponins from Paris fargesii var. brevipetala and cytotoxic activity of its main ingredient, paris saponin H.

    abstract::More attention was paid to the anti-tumor activity of Rhizoma Paridis (RP) recently, of which the wild resource was decreased significantly. This study was aimed to elucidate the chemical characteristics of Paris fargesii var. brevipetala (PFB) that may be administrated as alternate resource of legal RP. A HPLC-ELSD m...

    journal_title:Fitoterapia

    pub_type: 杂志文章

    doi:10.1016/j.fitote.2012.01.003

    authors: Wen F,Yin H,Chen C,Liu X,Xue D,Chen T,He J,Zhang H

    更新日期:2012-06-01 00:00:00