Two new benzofuran derivatives with anti-inflammatory activity from Liriope spicata var. prolifera.

abstract：:Two new neo-clerodane diterpenoids have been isolated from the whole plant of Scutellaria barbata D. Don, and their structures were established by detailed spectral analyses as scutehenanine H (1) and 6-(2,3-epoxy-2-isopropyl-n-propoxyl)barbatin C (2). In vitro, the isolated two new compounds showed significant cytoto...

journal_title：Fitoterapia

authors： Dai SJ,Qu GW,Yu QY,Zhang DW,Li GS

更新日期：2010-10-01 00:00:00

abstract：:Bioassay-guided fractionation of the dichloromethane extract of the fungus Neofusicoccum austral SYSU-SKS024 led to the isolation of three new ethylnaphthoquinone derivatives, neofusnaphthoquinone A (1), 6-(1-methoxylethy1)-2,7-dimethoxyjuglone (2), (3R,4R)-3-methoxyl-botryosphaerone D (6), together with six known ana...

journal_title：Fitoterapia

authors： Cui H,Zhang H,Liu Y,Gu Q,Xu J,Huang X,She Z

更新日期：2018-03-01 00:00:00

abstract：:Fruit's decoctions of Passiflora edulis and P. foetida var. albiflora were evaluated for the inhibition of activity of gelatinase MMP-2 and MMP-9, two metallo-proteases involved in the tumour invasion, metastasis and angiogenesis. Both water extracts, at different concentrations, inhibited the enzymes. ...

journal_title：Fitoterapia

authors： Puricelli L,Dell'Aica I,Sartor L,Garbisa S,Caniato R

更新日期：2003-04-01 00:00:00

abstract：:Five new 8-9' linked neolignans conchigeranals A-E (1-5), together with three known compounds galanganal (6), galanganols A (7) and B (8), were isolated from the whole plant of Alpinia conchigera. Their structures were established by spectroscopic analysis, including 2D-NMR spectroscopic techniques. Cytotoxicities of ...

journal_title：Fitoterapia

authors： Xu JJ,Zeng GZ,Yang SC,Shen Y,Tan NH

更新日期：2013-12-01 00:00:00

abstract：:A phytochemical investigation on the leaves of Tripterygium wilfordii Hook. F. was conducted, leading to the isolation of five undescribed dihydro-β-agarofuran sesquiterpenoids (1-5) and one known analogue (6). Their structures were determined by comprehensive spectroscopic analyses. The absolute configurations of the...

journal_title：Fitoterapia

authors： Zhao P,Lin B,Hou ZL,Zhou L,He QJ,Yao GD,Huang XX,Song SJ

更新日期：2020-04-01 00:00:00

abstract：:Crude CH2Cl2 extract from leaves of Piper laevicarpu (Piperaceae) displayed antitrypanosomal activity against trypomastigote forms of Trypanosoma cruzi (Y strain) and antimicrobial potential against Cryptococcus gattii (strain-type WM 178). Bioactivity-guided fractionation of crude extract afforded one new natural bio...

journal_title：Fitoterapia

authors： da Silva A Maciel D,Freitas VP,Conserva GA,Alexandre TR,Purisco SU,Tempone AG,Melhem MS,Kato MJ,Guimarães EF,Lago JH

更新日期：2016-06-01 00:00:00

abstract：:Ten new highly oxygenated lanostane triterpenoids, stereinones A-J (1-10), were isolated from the fruiting bodies of the basidiomycete Stereum sp. Compounds 3 and 4 are structurally characterized as intact lanostane-type triterpenoids containing unusual 1,2-diketone functionality at C-11 and C-12, while compound 10 is...

journal_title：Fitoterapia

authors： Yao JN,Chen L,Chen HP,Zhao ZZ,Zhang SB,Huang Y,Tang Y,Isaka M,Li ZH,Feng T,Liu JK

更新日期：2018-03-01 00:00:00

abstract：:Ganoderma cochlear, as edible and medicinal fungus, has long been used to prevent and treat various diseases. As our continuously phytochemical investigation of this fungus, a HPLC-UV-guided method led to the isolation of nine previously undescribed aromatic meroterpenoids with different ring systems, including six pa...

journal_title：Fitoterapia

authors： Peng X,Wang X,Chen L,Yang H,Li L,Lu S,Zhou L,Qiu M

更新日期：2018-06-01 00:00:00

abstract：:Nagilactones are norditerpene dilactones isolated from the root bark of Podocarpus nagi. Although nagilactone E has been reported to show antifungal activities, its activity is weaker than that of antifungals on the market. Nagilactone E enhances the antifungal activity of phenylpropanoids such as anethole and isosafr...

journal_title：Fitoterapia

authors： Hayashi K,Yamaguchi Y,Ogita A,Tanaka T,Kubo I,Fujita KI

更新日期：2018-07-01 00:00:00

abstract：:Phytochemical studies on the ethanol extract of the aerial parts of Ecdysanthera rosea led to the isolation of three new compounds, hydroquinone diglycoside acyl esters, ecdysanrosin A (1) and sesquiterpene, 5β-hydroperoxycostic acid (2) and apocarotenoid, 2, 4, 7-trimethyl-2, 4, 6, 8-tetraene-dialdehyde (3). Their st...

journal_title：Fitoterapia

authors： Zhu X,Zhang Q,Kong L,Wang F,Luo S

更新日期：2010-10-01 00:00:00

abstract：:Reinvestigation of Onopordon ambiguum extract afforded a new eudesmane derivative 1, in addition to the known elemanoid derivative 2. The structures of both compounds were determined by spectroscopic techniques, including 1H-, 13C-NMR, DEPT, 1H-1H and 1H-13C COSY analysis. ...

journal_title：Fitoterapia

authors： El-Moghazy SA,Ahmed AA,Abdel-Ghani HF,El-Shanawany MA

更新日期：2002-02-01 00:00:00

abstract：:Epiberberine, a natural protoberberine from Coptis chinensis Franch., is a potential alkaloid for the treatment of a variety of chronic diseases. The aim of this study is to summarize recent advances in the multiple and potential therapeutic effects of epiberberine. High-quality researches published in last two decade...

journal_title：Fitoterapia

authors： Liu L,Li J,He Y

更新日期：2020-11-01 00:00:00

abstract：:Two new pentacyclic triterpenes named kirmanoic acid (1) and kurramanoic acid (2) have been isolated from the chloroform-soluble portion of the whole plant of Nepeta clarkei Hook. The structures of the two new compounds were assigned on the basis of their ¹H and ¹³C NMR spectra including two-dimensional NMR techniques...

journal_title：Fitoterapia

authors： Hussain J,Ur Rehman N,Hussain H,Al-Harrasi A,Ali L,Rizvi TS,Ahmad M,Mehjabeen

更新日期：2012-04-01 00:00:00

abstract：:Two new clerodane diterpenoids 2 beta-methoxy-cleroda-3,13-dien-18-carboxy-15,16-olide (1) and 15 xi-methoxy-cleroda-3,12-dien-18-carboxy-15,16-olide (2) and one new nitrogen-containing clerodane diterpenoid 15-oxo-echinophyllin A (3), along with six known compounds, namely, echinophyllin A, (-)-patagonic acid, tyroso...

journal_title：Fitoterapia

authors： Wang W,Ali Z,Li XC,Smillie TA,Guo DA,Khan IA

更新日期：2009-10-01 00:00:00

abstract：:Four new C18-diterpenoid alkaloids, weisaconitines A-D (1-4), were isolated from Aconitum weixiense. Based on extensive UV, IR, MS, 1D and 2D NMR analyses, their structures were elucidated as 8-O-ethyldolaconine (1), 4-demethylgenicunine B (2), 14-oxoaconosine (3), and 8-O-ethylaconosine (4). The analgesic activity of...

journal_title：Fitoterapia

authors： Zhao DK,Ai HL,Zi SH,Zhang LM,Yang SC,Guo HC,Shen Y,Chen YP,Chen JJ

更新日期：2013-12-01 00:00:00

abstract：:Smyrnium olusatrum (Apiaceae), well known as wild celery, is a biennal celery-scented plant used for many centuries as a vegetable, then abandoned after the introduction of celery. In the present work, the essential oil obtained from inflorescences and the amounts of its main constituents isofuranodiene, curzerene and...

journal_title：Fitoterapia

authors： Quassinti L,Maggi F,Barboni L,Ricciutelli M,Cortese M,Papa F,Garulli C,Kalogris C,Vittori S,Bramucci M

更新日期：2014-09-01 00:00:00

abstract：:Two new isocoumarins (1 and 2), a new alkaloid (3), and a known N-acetyldopamine dimer (4) were isolated from the ethyl acetate extract of Chinese insect medicine Eupolyphaga sinensis. Their structures were elucidated on the basis of detailed spectroscopic investigations, such as 1D- and 2D NMR spectroscopy, as well a...

journal_title：Fitoterapia

authors： Jiang HL,Luo XH,Wang XZ,Yang JL,Yao XJ,Crews P,Valeriote FA,Wu QX

更新日期：2012-10-01 00:00:00

abstract：:A simple, sensitive and accurate liquid chromatographic method with photodiode-array detection was developed for determination of dehydroevodiamine with detection wavelength at 368 nm and column temperature at 30 degrees C. The separation was carried out on an Agilent Zorbax SB-C(18) column (250 mm x 4.6 mm, 5 microm)...

journal_title：Fitoterapia

authors： Zhao Y,Zhou X,Chen HG,Gong XJ,Cai ZW,Zhou CY

更新日期：2009-10-01 00:00:00

abstract：:Investigation of the bioactive secondary metabolites of the marine actinomycetes Rubrobacter radiotolerans led to the isolation and characterization of two naturally rare dimeric indole derivatives (1 and 2). The structures of these new compounds were elucidated by spectroscopic data interpretation, and the absolute c...

journal_title：Fitoterapia

authors： Li JL,Huang L,Liu J,Song Y,Gao J,Jung JH,Liu Y,Chen G

更新日期：2015-04-01 00:00:00

abstract：:Six new flavonoids, seladoeflavones A-F (1-6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroi...

journal_title：Fitoterapia

authors： Zou Z,Xu K,Xu P,Li X,Cheng F,Li J,Yu X,Cao D,Li D,Zeng W,Zhang G,Tan G

更新日期：2017-01-01 00:00:00

abstract：:Dichloromethane extract of propolis (DCME) originating from Pitcairn Island demonstrated potent cytotoxicity against triple-negative MDA-MB-231 human breast carcinoma cells. The results from MTT assay showed that DCME inhibits the growth of the cancer cells in a dose- and time-dependent manner and upon the cell growth...

journal_title：Fitoterapia

authors： Georgieva K,Trusheva B,Uzunova V,Stoyanova T,Valcheva V,Popova M,Tzoneva R,Bankova V

更新日期：2018-07-01 00:00:00

abstract：:Four new lignanamides, melongenamides A-D (1-4), together with six known ones (5-10), were isolated from the roots of Solanum melongena L. Their structures were elucidated on the basis of 1D and 2D NMR experiments and by comparison of their spectroscopic and physical data with the literature values. Compounds 2-8 exhi...

journal_title：Fitoterapia

authors： Sun J,Gu YF,Su XQ,Li MM,Huo HX,Zhang J,Zeng KW,Zhang Q,Zhao YF,Li J,Tu PF

更新日期：2014-10-01 00:00:00

abstract：:Biomass and secondary metabolite accumulation were assayed on a wide range of auxins, cytokinins and their combinations using Ecballium elaterium callus tissue. The best combination was that consisting of alpha-naphthalene acetic acid (NAA) and benzylamino purine (BAP) (1 mg/l of medium, each). NAA and BAP were set up...

journal_title：Fitoterapia

authors： Attard EG,Scicluna-Spiteri A

更新日期：2001-01-01 00:00:00

abstract：:The aim of the present research was to establish a comprehensive strategy to identify the metabolites of isoimperatorin after biotransformation with rat liver microsomes in vitro, and further describe metabolic kinetic characteristics of isoimperatorin and its main metabolites. Utilizing liquid chromatography with tim...

journal_title：Fitoterapia

authors： Chen TL,Zhang YB,Xu W,Kang TG,Yang XW

更新日期：2014-03-01 00:00:00

abstract：:The present study investigates the effect of in vivo administration of alcoholic extract of Tinospora cordifolia whole plant (ALTC) on the proliferation and myeloid differentiation of bone marrow hematopoietic precursor cells in mice bearing a transplantable T cell lymphoma of spontaneous origin designated as Dalton's...

journal_title：Fitoterapia

authors： Singh SM,Singh N,Shrivastava P

更新日期：2006-01-01 00:00:00

abstract：:Total sennosides concentration is a very important factor when rhubarb and senna will be used as crude drugs. However, one-step analytical technique for total sennosides has not been reported except HPLC. An enzyme-linked immunosorbent assay (ELISA) for total sennosides concentration by using the combination of anti-s...

journal_title：Fitoterapia

authors： Morinaga O,Uto T,Sakamoto S,Tanaka H,Shoyama Y

更新日期：2009-01-01 00:00:00

abstract：:Two spiro paclitaxel-mimics consisting only of an oxetane D-ring and a C-13 side chain were designed and synthesized on the basis of analysis of structure-activity relationships (SAR) of paclitaxel. In vitro microtubule-stabilizing and antiproliferative assays indicated a moderate weaker activity of the mimics than pa...

journal_title：Fitoterapia

authors： Chen XX,Gao F,Wang Q,Huang X,Wang D

更新日期：2014-01-01 00:00:00

abstract：:One new phenanthrene, aphyllone A (1) and four new bibenzyl derivatives, aphyllone B (2) and aphyllals C-D (3-5), together with nine known compounds (6-14), were isolated from the stems of Dendrobium aphyllum (Roxb.) C. E. Fischer. The structures of these new compounds were elucidated by means of extensive spectroscop...

journal_title：Fitoterapia

authors： Yang D,Liu LY,Cheng ZQ,Xu FQ,Fan WW,Zi CT,Dong FW,Zhou J,Ding ZT,Hu JM

更新日期：2015-01-01 00:00:00

abstract：:Six Patagonian plants were screened for proteolytic activity: Colliguaja integerrima, Euphorbia collina, E. peplus and Stillingia patagonica (Euphorbiaceae), Philibertia gilliesii (Asclepiadaceae) and Grindelia chiloensis (Asteraceae). P. gilliesii extracts showed the highest specific activity, followed by S. patagoni...

journal_title：Fitoterapia

authors： Sequeiros C,López LM,Caffini NO,Natalucci CL

更新日期：2003-09-01 00:00:00

abstract：:A new guanidine alkaloid, millaurine A (1), was isolated from the methanol extract of the seeds of Millettia laurentii. The structure of the new compound was elucidated on the basis of spectral analysis. ...

journal_title：Fitoterapia

authors： Ngamga D,Fanso Free SN,Tane P,Fomum ZT

更新日期：2007-04-01 00:00:00