Abstract:
:A simple, sensitive and accurate liquid chromatographic method with photodiode-array detection was developed for determination of dehydroevodiamine with detection wavelength at 368 nm and column temperature at 30 degrees C. The separation was carried out on an Agilent Zorbax SB-C(18) column (250 mm x 4.6 mm, 5 microm) together with a C(18) guard column. The mobile phase was acetonitrile-water (containing 30 mM sodium acetate trihydrate and 0.15% acetic acid) in the ratio of 30:70 (v/v) delivered at a flow rate of 1 mL/min. Excellent linear behavior was observed over the concentration range investigated, with correlation coefficient (R(2))=0.9998. This validated method was applied to determine the contents of dehydroevodiamine in 36 samples from different regions of China, and hierarchical clustering analysis was firstly used to classify and differentiate Evodia rutaecarpa samples. The analysis is specific and can be successfully applied to analyze E. rutaecarpa which is helpful for quality control of the herb.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Zhao Y,Zhou X,Chen HG,Gong XJ,Cai ZW,Zhou CYdoi
10.1016/j.fitote.2009.05.017subject
Has Abstractpub_date
2009-10-01 00:00:00pages
415-20issue
7eissn
0367-326Xissn
1873-6971pii
S0367-326X(09)00112-9journal_volume
80pub_type
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