Aromatic constituents from Ganoderma lucidum and their neuroprotective and anti-inflammatory activities.

abstract：:This manuscript reports on the first CE-method suitable for analyzing twelve pharmacologically relevant compounds (flavonoids, caffeic acids and leontopodic acid) in the aerial parts of Leontopodium alpinum. By using a 60mM borax buffer containing 25mM SDS and 35% acetonitrile the analytes could be well resolved in 25...

journal_title：Fitoterapia

authors： Ganzera M,Greifeneder V,Schwaiger S,Stuppner H

更新日期：2012-12-01 00:00:00

abstract：:The objective of this study was to evaluate potential hepatoprotective capabilities of quercetin in relation to its modulation of the HO-1 and NOS-2 activities in an experimental model of fulminant liver failure. Liver insult was induced by in vivo administration of D-galactosamine (d-GalN, 400 mg/kg, i.p.) and lipopo...

journal_title：Fitoterapia

authors： Lekić N,Canová NK,Hořínek A,Farghali H

更新日期：2013-06-01 00:00:00

abstract：:Epiberberine, a natural protoberberine from Coptis chinensis Franch., is a potential alkaloid for the treatment of a variety of chronic diseases. The aim of this study is to summarize recent advances in the multiple and potential therapeutic effects of epiberberine. High-quality researches published in last two decade...

journal_title：Fitoterapia

authors： Liu L,Li J,He Y

更新日期：2020-11-01 00:00:00

abstract：:Salvianolic acid B (Sal B) is the most abundant phenolic compound in Salvia miltiorrhiza, which has been widely used for the treatment of cardiovascular diseases in Oriental medicine. To elucidate structure of the converted compounds of Sal B by decoction in aqueous solution, Sal B (200 mg) was decocted in an aqueous ...

journal_title：Fitoterapia

authors： Lee HJ,Cho JY,Moon JH

更新日期：2012-10-01 00:00:00

abstract：:Five polyketides, paralactonic acids A-E (1-5) were isolated from Paraconiothyrium sp. SW-B-1, an endophytic fungus isolated from the seaweed, Chondrus ocellatus Holmes. Their structures were determined by various spectroscopic methods, predominantly by 2D NMR spectroscopic analyses. The absolute configurations of com...

journal_title：Fitoterapia

authors： Suzuki T,Ariefta NR,Koseki T,Furuno H,Kwon E,Momma H,Harneti D,Maharani R,Supratman U,Kimura KI,Shiono Y

更新日期：2019-01-01 00:00:00

abstract：:Psychotria is a complex genus whose neotropical species are known by the presence of glucosidic monoterpene indole alkaloids. These compounds are able to display a large range of effects on the central nervous system, such as anxiolytic, antidepressant, analgesic, and impairment of learning and memory acquisition. The...

journal_title：Fitoterapia

authors： Farias FM,Passos CS,Arbo MD,Barros DM,Gottfried C,Steffen VM,Henriques AT

更新日期：2012-09-01 00:00:00

abstract：:Ailanthone (AIL) has many biological activities including antimalarial, antiviral and anticancer. Our previous study also found that AIL targets p23 against castration-resistant prostate cancer. In this report, the preclinical safety of AIL was evaluated by acute toxicity, subacute toxicity and toxicokinetics in mice....

journal_title：Fitoterapia

authors： Tang S,Ma X,Lu J,Zhang Y,Liu M,Wang X

更新日期：2019-07-01 00:00:00

abstract：:From the roots of Smilax bockii a new compound, 7-hydroxymethyl-1, 4, 5-trihydroxynaphthalene-4-O-beta-D-xylopyranosyl(1-->6)-beta-D-glucopyranoside, was isolated. The structure of the new compound was elucidated on the basis of spectroscopic methods. ...

journal_title：Fitoterapia

authors： Li X,Xu J,Zhang P,Li N,Meng DL

更新日期：2008-09-01 00:00:00

abstract：:A new flavone, 4'-hydroxy-6,7-methylenedioxy-3-methoxyflavone 1, and two other nucleosides, ribavirin 2 and adenosine 3, were isolated from the leaves of Dulacia egleri. The nucleosides were identified by spectroscopic techniques (1D, 2D-NMR) while the structure of the flavonoid was established by 1D, 2D-NMR analysis,...

journal_title：Fitoterapia

authors： de Novais LMR,de Arueira CCO,Ferreira LF,Ribeiro TAN,Sousa PT Jr,Jacinto MJ,de Carvalho MG,Judice WAS,Jesus LOP,de Souza AA,Torquato HFV,Paredes-Gamero EJ,Silva VC

更新日期：2019-01-01 00:00:00

abstract：:Two new depsidones, schomburgdepsidones A and B (1 and 2), and one new xanthone, schomburgxanthone A (3), together with eight known compounds (4-11) were isolated from the roots of Garcinia schomburgkiana. Their chemical structures were established on the basis of spectroscopic analysis. The in vitro cytotoxicity of a...

journal_title：Fitoterapia

authors： Sukandar ER,Siripong P,Khumkratok S,Tip-Pyang S

更新日期：2016-06-01 00:00:00

abstract：:Four new sesquiterpenes (1-2, 6-7), a new pyranone glycoside (10) along with six known compounds, were isolated from the whole plant of Erigeron breviscapus. Their planar structures were elucidated using extensive spectroscopic analyses. Brevisterpene A (1) and brevisterpene B (2) were proved to be a pair of diastereo...

journal_title：Fitoterapia

authors： Han S,Liu Y,Hou Z,Sun X,Yao G,Gao P,Li L,Song S

更新日期：2019-10-01 00:00:00

abstract：:The effects of the aqueous extract of the leaf of Euphrasia officinale on blood glucose levels in normal and alloxan-diabetic rats were investigated. The treatment of alloxan-induced diabetic rats brought down the raised glucose levels, while the extract was devoid of hypoglycemic effect in normal rats. ...

journal_title：Fitoterapia

authors： Porchezhian E,Ansari SH,Shreedharan NK

更新日期：2000-09-01 00:00:00

abstract：:Two new alkaloids, named stenine A (1) and stenine B (2), along with the known compounds neostenine (3), stenine (4) and neotuberostemonine (5), were isolated from the roots of Stemona sessilifolia. Their structures were elucidated by 1D- and 2D-NMR spectra and X-ray single-crystal diffraction experiment. Anti-acetylc...

journal_title：Fitoterapia

authors： Lai DH,Yang ZD,Xue WW,Sheng J,Shi Y,Yao XJ

更新日期：2013-09-01 00:00:00

abstract：:The crude methanolic extracts of Hygrophila scricta and Peperomia pellucida were fractionated into petrol, dichloromethane, ethyl acetate and butanol. All the crude extracts and the fractions exhibited a very good level of broad spectrum antibacterial activity. The fractions were more active than the crude extracts. T...

journal_title：Fitoterapia

authors： Khan MR,Omoloso AD

更新日期：2002-06-01 00:00:00

abstract：:The antioxidant effect of aqueous methanolic herb extracts of Serratula coronata, S. wolffii and S. tinctoria was investigated using both enzyme-dependent and enzyme-independent systems. The extracts displayed concentration-dependent inhibition of lipid peroxidation. Flavonoids and ecdysteroids present in the extracts...

journal_title：Fitoterapia

authors： Báthori M,Zupkó I,Hunyadi A,Gácsné-Baitz E,Dinya Z,Forgó P

更新日期：2004-03-01 00:00:00

abstract：:Seven new lignan glycosides (1-3, 8-10, and 14) and 17 known compounds were isolated from the branches of Alangium kurzii Craib var. laxifolium. Their structures were established by spectroscopic analysis and circular dichroism (CD) and X-ray analysis. The isolated compounds were evaluated for their antibacterial acti...

journal_title：Fitoterapia

authors： Ren J,Xie YG,Huang YY,Zhu SL,Yan SK,Jin HZ,Zhang WD

更新日期：2017-09-01 00:00:00

abstract：:Black carrot (Daucus carota L. ssp. sativus var. atrorubens Alef.) is a valuable source of carbohydrates, minerals and vitamins and contains also high amounts of anthocyanins giving the characteristic deep-purple color. These latter compounds are known as natural dyes used in the food and pharmaceutical industry that ...

journal_title：Fitoterapia

authors： Smeriglio A,Denaro M,Barreca D,D'Angelo V,Germanò MP,Trombetta D

更新日期：2018-01-01 00:00:00

abstract：:The aim of the present research was to establish a comprehensive strategy to identify the metabolites of isoimperatorin after biotransformation with rat liver microsomes in vitro, and further describe metabolic kinetic characteristics of isoimperatorin and its main metabolites. Utilizing liquid chromatography with tim...

journal_title：Fitoterapia

authors： Chen TL,Zhang YB,Xu W,Kang TG,Yang XW

更新日期：2014-03-01 00:00:00

abstract：:Seven compounds were isolated from the roots of Eurycoma longifolia, and characterized by comprehensive analysis of 1D and 2D NMR experiments along with single crystal X-ray diffraction. Among them, four new quassinoids were identified and three of them were diastereomers for each other. Compounds 1-7 were evaluated f...

journal_title：Fitoterapia

authors： Meng D,Li X,Han L,Zhang L,An W,Li X

更新日期：2014-01-01 00:00:00

abstract：:Hispolon was the main antitumor active ingredient in Phellinus sensu lato species. In order to confirm the dual regulating estrogenic ingredient and obtain more effective natural estrogen replacement drugs, hispolon was separated from Phellinus lonicerinus (Bond.) Bond. et sing. Hispolon exhibited significant anti-pro...

journal_title：Fitoterapia

authors： Wang J,Hu F,Luo Y,Luo H,Huang N,Cheng F,Deng Z,Deng W,Zou K

更新日期：2014-06-01 00:00:00

abstract：:Two new ent-kaurene diterpenoids, 15α-acetoxyl-6,11α-epoxy-6α-hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7-olide (1), 15α-hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α(6,11α)-diolide (2), together with ten known compounds (5-14) were isolated from the leaves of Isodon rubescens. Their structures were elucidated mainly by ...

journal_title：Fitoterapia

authors： Xie RJ,Yan FL,Hai GF,Hou RJ,Ding MM,Bai YX

更新日期：2011-06-01 00:00:00

abstract：:Rapid micropropagation of Nepeta rtanjensis, N. sibirica and N. nervosa was performed. Qualitative and quantitative nepetalactone content in methanol extracts of in vitro grown plants was analysed by reverse-phase HPLC coupled with UV and MS detection. Only trans,cis-nepetalactone was detected in shoots of N. rtanjens...

journal_title：Fitoterapia

authors： Nestorović J,Misić D,Siler B,Soković M,Glamoclija J,Cirić A,Maksimović V,Grubisić D

更新日期：2010-09-01 00:00:00

abstract：:Usually isolated from Garcinia (Clusiaceae) or Hypericum (Hypericaceae) species, some Polycyclic Polyprenylated AcylPhloroglucinols (PPAPs) have been recently reported as potential research tools for immunotherapy. Aiming at exploring the chemodiversity of PPAPs amongst Garcinia genus, a dereplication process suitable...

journal_title：Fitoterapia

authors： Bruguière A,Derbré S,Coste C,Le Bot M,Siegler B,Leong ST,Sulaiman SN,Awang K,Richomme P

更新日期：2018-11-01 00:00:00

abstract：:6,7-Dimethylesculetin (D), geniposide (G) and rhein (R) are the three major active ingredients of Yin-Chen-Hao-Tang (YCHT), a famous Chinese herbal formula, which has been shown to be clinically effective for treating hepatic injury (HI) syndrome. The present study was conducted to investigate the therapeutic and syne...

journal_title：Fitoterapia

authors： Zhang A,Sun H,Yuan Y,Sun W,Jiao G,Wang X

更新日期：2011-12-01 00:00:00

abstract：:A new sulfur-containing iridoid glucoside, named paederoside B, was isolated from the stems of Paederia scandens. The structure of the new compound was elucidated as paederosidyl paederosidate by spectral evidence. ...

journal_title：Fitoterapia

authors： Zou X,Peng S,Liu X,Bai B,Ding L

更新日期：2006-07-01 00:00:00

abstract：:The therapeutic uses and methods of administration of 70 plants in the traditional medicine of Sarrabus (south-east Sardinia, Italy) are documented. Among these species, some were not reported previously for Sardinia, while others turn out to have an original therapeutic use. ...

journal_title：Fitoterapia

authors： Palmese MT,Uncini Manganelli RE,Tomei PE

更新日期：2001-08-01 00:00:00

abstract：:Three new steroidal glycosides (1-3) and a novel natural product 4 firstly obtained from a plant source, together with two known steroidal glycosides (5-6) have been isolated from the whole plant of Reineckia carnea. Their structures were determined by physicochemical properties and spectroscopic methods, and their cy...

journal_title：Fitoterapia

authors： Song X,Zhang D,He H,Li Y,Yang X,Deng C,Tang Z,Cui J,Yue Z

更新日期：2015-09-01 00:00:00

abstract：:The effect of schisandrin B (Sch B) on long-term ethanol-induced oxidative stress in various rat tissues was investigated. Long-term ethanol treatment increased reactive oxygen metabolites (ROM) level in plasma. The ethanol-induced oxidative stress was assessed by mitochondrial glutathione and α-tocopherol levels, ant...

journal_title：Fitoterapia

authors： Lam PY,Chiu PY,Leung HY,Chen N,Leong PK,Ko KM

更新日期：2010-12-01 00:00:00

abstract：:Two new glycosides, 2-methyl-L-erythritol-4-O-(6-O-trans-sinapoyl)-β-D-glucopyranoside (1) and 2-methyl-L-erythritol-1-O-(6-O-trans-sinapoyl)-β-D-glucopyranoside (2), along with two known triterpenoids (3-4), four quinic acid derivatives (5-8) and one flavonoid (9) were isolated from the fruit of Gardenia jasminoides....

journal_title：Fitoterapia

authors： Yang L,Peng K,Zhao S,Zhao F,Chen L,Qiu F

更新日期：2013-09-01 00:00:00

abstract：:The antimicrobial and cytotoxic activities of six lignans isolated from the core and bark acetone extracts of Hibiscus cannabinus have been investigated. Two compounds (2 and 3) showed strong cytotoxic activity against HeLa, Hep-2 and A-549 cell lines while compound 5 showed moderate activity on HeLa cells when they w...

journal_title：Fitoterapia

authors： Moujir L,Seca AM,Silva AM,López MR,Padilla N,Cavaleiro JA,Neto CP

更新日期：2007-07-01 00:00:00