Abstract:
:Commiphoins A-C (1-3), three new cadinane-type sesquiterpenes, together with two known cadinane-type sesquiterpenes (4 and 5) were isolated from the resinous exudates of Commiphora myrrha. Their structures and relative configurations were established on the basis of comprehensive spectroscopic methods, including HRESIMS, 1D and 2D NMR analyses. Compounds 1 and 3-5 were screened for anti-Alzheimer's disease (AD) activities using the AD pathological model in Caenorhabditis elegans. The results showed that they all had significant anti-AD activities.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Yu YF,Liu YH,Chen XH,Zhi DJ,Qi FM,Zhang ZP,Li YQ,Zhang ZX,Fei DQdoi
10.1016/j.fitote.2020.104536subject
Has Abstractpub_date
2020-04-01 00:00:00pages
104536eissn
0367-326Xissn
1873-6971pii
S0367-326X(20)30118-0journal_volume
142pub_type
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