New depsidones and xanthone from the roots of Garcinia schomburgkiana.

abstract：:Four new sesquiterpenoids, phellinignins A-D (1-4), together with four known ones (5-8), were isolated from cultures of the fungus Phellinus igniarius. The structures were established by extensive spectroscopic methods including MS, NMR, and the single crystal X-ray diffraction. Compounds 1-3 and 5-8 are tremulane ses...

journal_title：Fitoterapia

authors： Wu PF,Ding R,Tan R,Liu J,Hu EM,Li CY,Liang GY,Yi P

更新日期：2020-01-01 00:00:00

abstract：:Human carboxylesterase 1 (CES1), primarily expressed in the liver and adipocytes, is responsible for the hydrolysis of endogenous esters (such as cholesteryl esters and triacylglycerols) and the metabolism of xenobiotic esters (such as clopidogrel and oseltamivir), thus participates in physiological and pathological p...

journal_title：Fitoterapia

authors： Song PF,Zhu YD,Ma HY,Wang YN,Wang DD,Zou LW,Ge GB,Yang L

更新日期：2019-09-01 00:00:00

abstract：:A new guanidine alkaloid, millaurine A (1), was isolated from the methanol extract of the seeds of Millettia laurentii. The structure of the new compound was elucidated on the basis of spectral analysis. ...

journal_title：Fitoterapia

authors： Ngamga D,Fanso Free SN,Tane P,Fomum ZT

更新日期：2007-04-01 00:00:00

abstract：:Ten new tricyclic prezizaane types sesquiterpenoids (1-10) were isolated from ethyl ether extract of agarwood originated from Aquilaria sp. Their structures were unambiguously elucidated on the basis of 1D and 2D NMR spectra as well as by HRESIMS data. The absolute configuration of the new prezizaenes 1, 2 and 4 was d...

journal_title：Fitoterapia

authors： Yang YL,Li W,Wang H,Yang L,Yuan JZ,Cai CH,Chen HQ,Dong WH,Ding XP,Jiang B,Mándi A,Kurtán T,Mei WL,Dai HF

更新日期：2019-10-01 00:00:00

abstract：:Six previously undescribed compounds, named monaxanthones A and B, monaphenol A, monathioamide A, monaprenylindole A, and monavalerolactone A, were isolated from the culture of a marine-sourced bacterium Pseudomonas sp. ZZ820R in rice medium. Their structures were elucidated based on the HRESIMS data, NMR and MS-MS sp...

journal_title：Fitoterapia

authors： Yi W,Ge ZW,Wu B,Zhang Z

更新日期：2020-06-01 00:00:00

abstract：:Five pairs of new 2-oxoindole alkaloids, (±)-peganumalines A-E (1-5), and a new indole alkaloid, peganumaline F (6), along with two known analogues, were isolated from the seeds of Peganum harmala. Their structures and absolute configurations were elucidated through spectroscopic analyses and quantum chemistry calcula...

journal_title：Fitoterapia

authors： Wang KB,Hu X,Li SG,Li XY,Li DH,Bai J,Pei YH,Li ZL,Hua HM

更新日期：2018-03-01 00:00:00

abstract：:The phytochemical studies on the aerial parts of Digitalis davisiana Heywood led to the isolation of three undescribed phenylethanoid glycosides named as digidavisoside A (5), digidavisoside B (7), and davisoside (8), along with 9 known compounds, ferruginoside B (1), isolugrandoside (2), lugrandoside (3), maxoside (4...

journal_title：Fitoterapia

authors： Kutluay VM,Ishiuchi K,Makino T,Saracoglu I

更新日期：2019-06-01 00:00:00

abstract：:Seven compounds were isolated from the roots of Eurycoma longifolia, and characterized by comprehensive analysis of 1D and 2D NMR experiments along with single crystal X-ray diffraction. Among them, four new quassinoids were identified and three of them were diastereomers for each other. Compounds 1-7 were evaluated f...

journal_title：Fitoterapia

authors： Meng D,Li X,Han L,Zhang L,An W,Li X

更新日期：2014-01-01 00:00:00

abstract：:Four new lathyrane-type diterpenoids (1-4) and a novel macrocyclic diterpenoid (5) featuring a 5/7/7/4-fused ring system, together with seventeen known ones (6-22), were isolated from the seeds of Euphorbia lathyris. Their structures were elucidated by extensive spectroscopic analyses and single crystal X-ray crystall...

journal_title：Fitoterapia

authors： Zuo Q,Mu HY,Gong Q,Ding X,Wang W,Zhang HY,Zhao WM

更新日期：2021-01-26 00:00:00

abstract：:The flavonoid baicalein has been demonstrated to be an activator of the transcription factor Nrf2 in mammalian cell lines. We show that it further modulates the Nrf2 homolog SKN-1 in Caenorhabditis elegans and by this pathway mediates beneficial effects in the nematode: baicalein enhances the resistance of C. elegans ...

journal_title：Fitoterapia

authors： Havermann S,Humpf HU,Wätjen W

更新日期：2016-09-01 00:00:00

abstract：:Bioassay-directed separation of the chloroform extracts from the air-dried aerial part of Alhagi pseudalhagi (M.B.) led to the isolation of a new isoflavonolignan (1), together with five known isoflavones (2-6) (Fig. 1). Their structures were identified on the basis of spectral analysis of NMR, MS, IR, UV and CD spect...

journal_title：Fitoterapia

authors： Li N,Zhang G,Xiong Y,Makhabel B,Li X,Jia X

更新日期：2010-12-01 00:00:00

abstract：:A new megastigmane sesquiterpene glucoside named chaihuxinoside A (1), and a new indole diglucoside named chaihuxinoside B (9) were isolated from the aerial parts of Bupleurum chinense DC. along with eight known compounds. Structures of two new compounds were elucidated by a combination of chemical and spectroscopic m...

journal_title：Fitoterapia

authors： Kuang H,Sun S,Yang B,Xia Y,Feng W

更新日期：2009-01-01 00:00:00

abstract：:Total sennosides concentration is a very important factor when rhubarb and senna will be used as crude drugs. However, one-step analytical technique for total sennosides has not been reported except HPLC. An enzyme-linked immunosorbent assay (ELISA) for total sennosides concentration by using the combination of anti-s...

journal_title：Fitoterapia

authors： Morinaga O,Uto T,Sakamoto S,Tanaka H,Shoyama Y

更新日期：2009-01-01 00:00:00

abstract：:Caper (Capparis L.), a shrub plant with a large natural distribution, is used in traditional medicines to cure various illnesses. Phytochemicals studies have shown the presence of many beneficial compounds such as spermidine, rutin, quercetin, kaempferol, stigmasterol, campesterol, tocopherols, and carotenoids. Biolog...

journal_title：Fitoterapia

authors： Tlili N,Elfalleh W,Saadaoui E,Khaldi A,Triki S,Nasri N

更新日期：2011-03-01 00:00:00

abstract：:Two new alkaloidal metabolites, cordytakaoamides A (1) and B (2), as well as, 2-[(2-hydroxyethyl) amino] benzoic acid (3) and 2E-decenamide (4), and three known compounds (5-7) were isolated from ethyl acetate and n-butanol soluble portions of the entomopathogenic fungus, Cordyceps takaomontana NBRC 101754. Compounds ...

journal_title：Fitoterapia

authors： Hama M,Elshamy AI,Yoneyama T,Kasai Y,Yamamoto H,Tanigawa K,Oshiro A,Noji M,Ban S,Imagawa H,Umeyama A

更新日期：2019-11-01 00:00:00

abstract：:The irritant potential of total methanolic extract and five triterpenoids newly isolated from the leaves of Ficus carica investigated by open mouse ear assay. Total methanolic extract, calotropenyl acetate, methyl maslinate and lupeol acetate showed potent and persistent irritant effects. ...

journal_title：Fitoterapia

authors： Saeed MA,Sabir AW

更新日期：2002-08-01 00:00:00

abstract：:Four new aristolochic acid derivatives aristchamic A (1), aristchamic B (2), aristochamic C (3a), aristchamic D (3b) and one new aristolactam aristolactam-CV (4), together with 10 known compounds (5-14), were isolated from the rhizomes of Aristolochia championii. Their structures were assigned by detailed analysis of ...

journal_title：Fitoterapia

authors： Wang X,Shi GR,Liu YF,Li L,Chen RY,Yu DQ

更新日期：2017-04-01 00:00:00

abstract：:Glabridin, a prenylated isoflavonoid of G. glabra L. roots (European licorice, Fabaceae), has been associated with a wide range of biological properties such as antioxidant, anti-inflammatory, anti-atherogenic, regulation of energy metabolism, estrogenic, neuroprotective, anti-osteoporotic, and skin-whitening. While g...

journal_title：Fitoterapia

authors： Simmler C,Pauli GF,Chen SN

更新日期：2013-10-01 00:00:00

abstract：:Methanol extract of the stem bark of Hymenodictyon parvifolium was tested for its antifungal and antibacterial activity. The extract was found to have inhibitory effect against all the pathogens tested. ...

journal_title：Fitoterapia

authors： Kariba RM

更新日期：2002-10-01 00:00:00

abstract：:Four new eburnamine-aspidospermine type bisindole alkaloids, namely, mekongenines C-F (1-4), along with 27 known indole alkaloids were isolated from the twigs and leaves of Bousigonia mekongensis. Their structures with the absolute configurations were elucidated by spectroscopic methods and ECD analyses. All new compo...

journal_title：Fitoterapia

authors： Fu YH,Li SL,Li SF,He HP,Di YT,Zhang Y,Hao XJ

更新日期：2014-10-01 00:00:00

abstract：:Three new xanthones, named kaennacowanols A-C (1-3), along with nineteen known xanthones were isolated from the roots of Garcinia cowa Roxb. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their cytotoxicity against KB and HeLa cell lines. Compounds 17 and 22 showe...

journal_title：Fitoterapia

authors： Kaennakam S,Siripong P,Tip-Pyang S

更新日期：2015-04-01 00:00:00

abstract：:The effects of the aqueous extract of the leaf of Euphrasia officinale on blood glucose levels in normal and alloxan-diabetic rats were investigated. The treatment of alloxan-induced diabetic rats brought down the raised glucose levels, while the extract was devoid of hypoglycemic effect in normal rats. ...

journal_title：Fitoterapia

authors： Porchezhian E,Ansari SH,Shreedharan NK

更新日期：2000-09-01 00:00:00

abstract：:The objective of this study was to evaluate potential hepatoprotective capabilities of quercetin in relation to its modulation of the HO-1 and NOS-2 activities in an experimental model of fulminant liver failure. Liver insult was induced by in vivo administration of D-galactosamine (d-GalN, 400 mg/kg, i.p.) and lipopo...

journal_title：Fitoterapia

authors： Lekić N,Canová NK,Hořínek A,Farghali H

更新日期：2013-06-01 00:00:00

abstract：:Isorhynchophylline is one of the major alkaloids from the Uncaria hook possessing the effects of lowered blood pressure, vasodilatation and protection against ischemia-induced neuronal damage. However, the metabolic pathway of isorhynchophylline has not been fully reported yet. In this paper, the metabolism of isorhyn...

journal_title：Fitoterapia

authors： Chen F,Qi W,Sun J,Simpkins JW,Yuan D

更新日期：2014-09-01 00:00:00

abstract：:The antioxidant activity of the methanol extract of Hypericum triquetrifolium Turra (Hypericaceae) aerial part and of flavonoids isolated therein, I3,II8-biapigenin, quercetin-3-O-galactoside, kaempferol-3-O-glycoside, (-)-epicatechin and hypericin, was evaluated. The IC(50) resulted between 0.062 and 1 mg/ml. ...

journal_title：Fitoterapia

authors： Conforti F,Statti GA,Tundis R,Menichini F,Houghton P

更新日期：2002-10-01 00:00:00

abstract：:Two new steroidal esters with an unusual framework, Sinkiangenorin A and B, a new organic acid glycoside, Sinkiangenorin C, and four known lignin compounds were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds were established by spectroscopic analysis and single-crystal X-ray diffrac...

journal_title：Fitoterapia

authors： Li G,Li X,Cao L,Shen L,Zhu J,Zhang J,Wang J,Zhang L,Si J

更新日期：2014-09-01 00:00:00

abstract：:Ethanol extract of Maytenus rigida stem bark and its fractions were assessed for antinociceptive activity in tail-flick test in rats. The activity was located in the chloroform, ethyl acetate and aq.methanol fractions. Phytochemical screening revealed that catechin was the only common class of compounds present on the...

journal_title：Fitoterapia

authors： Dias KS,Marques MS,Menezes IA,Santos TC,Silva AB,Estevam CS,Sant'Ana AE,Pizza C,Antoniolli AR,Marçal RM

更新日期：2007-12-01 00:00:00

abstract：:Glucocorticoids (GCs) are usually used to treat inflammatory diseases. However, they cause severe and irreversible side effects, which limit the use of these compounds. Ginsenoside Rg1 had been demonstrated to possess anti-inflammatory and anti-cancer effects. The present study was designed to investigate whether Rg1 ...

journal_title：Fitoterapia

authors： Song Y,Zhao F,Zhang L,Du Y,Wang T,Fu F

更新日期：2013-12-01 00:00:00

abstract：:One new Euphane-type triterpenoid 3β-hydroxytirucalla-5, 24-dien-21-oic acid (1), and ten known compounds (2-11) were isolated from Melia azedarach L. through bioassay-guided chemical analysis. The structures of the isolated compounds were established by means of 1D and 2D NMR spectroscopic ((1)H, (13)C, DEPT, COSY, H...

journal_title：Fitoterapia

authors： Khan MF,Rawat AK,Pawar B,Gautam S,Srivastava AK,Negi DS

更新日期：2014-10-01 00:00:00

abstract：:Seven new lignan glycosides (1-3, 8-10, and 14) and 17 known compounds were isolated from the branches of Alangium kurzii Craib var. laxifolium. Their structures were established by spectroscopic analysis and circular dichroism (CD) and X-ray analysis. The isolated compounds were evaluated for their antibacterial acti...

journal_title：Fitoterapia

authors： Ren J,Xie YG,Huang YY,Zhu SL,Yan SK,Jin HZ,Zhang WD

更新日期：2017-09-01 00:00:00