Antinociceptive activity of Maytenus rigida stem bark.

abstract：:Phytochemical investigation of methanolic extract of the whole plants of Vaccinium emarginatum allowed for the characterization of one epicatechin derivative (1) that was isolated from a natural source for the first time and three new flavonoids, emarginin A (2), emarginin B (3), and emarginin C (4), together with 11 ...

journal_title：Fitoterapia

authors： Tu PC,Liang YC,Huang GJ,Huang HC,Kao MC,Lu TL,Kuo YH

更新日期：2020-03-01 00:00:00

abstract：:The therapeutic uses and methods of administration of 70 plants in the traditional medicine of Sarrabus (south-east Sardinia, Italy) are documented. Among these species, some were not reported previously for Sardinia, while others turn out to have an original therapeutic use. ...

journal_title：Fitoterapia

authors： Palmese MT,Uncini Manganelli RE,Tomei PE

更新日期：2001-08-01 00:00:00

abstract：:Five new guaiane-type sesquiterpenoids were obtained from the roots of Daphne genkwa. Their gross structures were established by extensive spectroscopic analyses. Attempts on the assignment of the relative configurations were unsuccessful when based on the NOESY correlations. Therefore, NMR chemical shift calculations...

journal_title：Fitoterapia

authors： Wang J,Ren Q,Zhang YY,Guo R,Lin B,Huang XX,Song SJ

更新日期：2019-10-01 00:00:00

abstract：:Three new cycloartane triterpenoids (1-3) and two known compounds (4, 5) were isolated from the whole plant of Beesia calthaefolia. Their structures were elucidated by 1D and 2D NMR, HRESIMS and optical rotation spectral data. All isolates were investigated for their inhibitory effects on the classical pathway of the ...

journal_title：Fitoterapia

authors： Mu LH,Li HJ,Guo DH,Zhao JY,Liu P

更新日期：2014-01-01 00:00:00

abstract：:The ethanolic extracts of Lawsonia inermis leaves, Holarrhena antidysenterica bark, Swertia chirata whole plant and Mangifera indica bark were tested (in-vitro) for alpha-glucosidase inhibitory activity. M. indica extract was found to be the most potent, with an IC(50) value of 314 microg/ml. ...

journal_title：Fitoterapia

authors： Prashanth D,Amit A,Samiulla DS,Asha MK,Padmaja R

更新日期：2001-08-01 00:00:00

abstract：:CTPS-01, a water-soluble polysaccharide, was obtained from the root of Cudrania tricuspidata and estimated to have an average molecular weight of 5.9 x 10(3) and to be composed of glucose residues, solely. It contains an average repeating unit of decasaccharide, having a backbone consisting of 1,4-linked alpha-D-gluco...

journal_title：Fitoterapia

authors： Shi L,Fu YL,Chen KS

更新日期：2007-06-01 00:00:00

abstract：:Thirty-five crude extracts from 11 Panamanian plants, distributed in 10 genera and five families, were evaluated for their in vitro cytotoxicity. Four extracts exhibited an inhibition of cellular growth at IC(50) values lower than 25 microg/ml which was considered a significant activity. ...

journal_title：Fitoterapia

authors： Calderón AI,Terreaux C,Gupta MP,Hostettmann K

更新日期：2003-06-01 00:00:00

abstract：:A phytochemical fractionation of the methanol extract of the Morus alba leaves led to the isolation of eleven flavonoids (1-11). The structure of the new 3'-geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone (1) was elucidated by means of spectroscopic methods. The cytotoxicity of the isolated compounds against human cerv...

journal_title：Fitoterapia

authors： Dat NT,Binh PT,Quynh le TP,Van Minh C,Huong HT,Lee JJ

更新日期：2010-12-01 00:00:00

abstract：:Four new lignanamides, melongenamides A-D (1-4), together with six known ones (5-10), were isolated from the roots of Solanum melongena L. Their structures were elucidated on the basis of 1D and 2D NMR experiments and by comparison of their spectroscopic and physical data with the literature values. Compounds 2-8 exhi...

journal_title：Fitoterapia

authors： Sun J,Gu YF,Su XQ,Li MM,Huo HX,Zhang J,Zeng KW,Zhang Q,Zhao YF,Li J,Tu PF

更新日期：2014-10-01 00:00:00

abstract：:Herbal medicines are the most globally used type of medical drugs. Their high cultural acceptability is due to the experienced safety and efficiency over centuries of use. Many of them are still phytochemically less-investigated, and are used without standardization or quality control. Choosing SIROP KILMA, an authori...

journal_title：Fitoterapia

authors： Tshitenge DT,Ioset KN,Lami JN,Ndelo-di-Phanzu J,Mufusama JP,Bringmann G

更新日期：2016-04-01 00:00:00

abstract：:The methanol extracts of Clematis papuasica leaves and stem bark and of Nauclea obversifolia leaves, stem and root barks showed awide spectrum of antibacterial activity which was increased on fractionation (petrol, dichloromethane, ethyl acetate), the ethyl acetate fractions being in all cases the most effective. None...

journal_title：Fitoterapia

authors： Khan MR,Kihara M,Omoloso AD

更新日期：2001-06-01 00:00:00

abstract：:Diterpene alkaloids neoline (1), napelline (2), isotalatizidine (3), karakoline (4), senbusine A (5), senbusine C (6), aconitine (7) and taurenine (8) were identified from Aconitum napellus L. subsp. firmum, four (2-4, 6) of which are reported for the first time from this plant. The structures were determined by means...

journal_title：Fitoterapia

authors： Kiss T,Orvos P,Bánsághi S,Forgo P,Jedlinszki N,Tálosi L,Hohmann J,Csupor D

更新日期：2013-10-01 00:00:00

abstract：:Before the design of brucine-containing transdermal formulations, the pharmacodynamics and pharmacokinetics of brucine following transdermal administration should be evaluated. In this study, the effect of addition of ethanol on solubility of bruicne was investigated and 20% ethanol was added into PBS to obtain 10mg/m...

journal_title：Fitoterapia

authors： Chen J,Hu W,Qu YQ,Dong J,Gu W,Gao Y,Fang Y,Fang F,Chen ZP,Cai BC

更新日期：2013-04-01 00:00:00

abstract：:Four new dihydrophenanthrenofuran, bleochranols A-D (1-4), along with 21 known compounds including phenanthrenes (5-14) and bibenzyls (15-25) were isolated and elucidated from the rhizomes of Bletilla ochracea. Combination of 1D/2D NMR techniques and the Electronic Circular Dichroism (ECD) spectroscopy based on the em...

journal_title：Fitoterapia

authors： Li JY,Kuang MT,Yang L,Kong QH,Hou B,Liu ZH,Chi XQ,Yuan MY,Hu JM,Zhou J

更新日期：2018-06-01 00:00:00

abstract：:Flos Chrysanthemi (the flower of Chrysanthemum morifolium Ramat.) is widely used in China as a food and traditional Chinese medicine for many diseases. Luteolin and apigenin are two main bioactive components in Flos Chrysanthemi, and chrysoeriol and diosmetin are two methylated metabolites of luteolin in vivo by cathe...

journal_title：Fitoterapia

authors： Chen Z,Kong S,Song F,Li L,Jiang H

更新日期：2012-12-01 00:00:00

abstract：:Eighteen alkaloids were detected in the bark, leaves, wood and roots of Peumus boldus, including traces of secoboldine, N-methylsecoboldine (boldine methine), glaucine and norreticuline, not reported previously as constituents of this species. Using appropriate standards, we quantified thirteen of them by UHPLC-MS/MS....

journal_title：Fitoterapia

authors： Fuentes-Barros G,Castro-Saavedra S,Liberona L,Acevedo-Fuentes W,Tirapegui C,Mattar C,Cassels BK

更新日期：2018-06-01 00:00:00

abstract：:The isolation of cinchonicine-derived alkaloids epicinchonicinol (1), cinchonidicinol (2) and a mixture of dihydrocinchonicinol and dihydrocinchonidicinol (3) from the dried bark of Ladenbergia oblongifolia, is reported along with (1)H and (13)C-NMR data. ...

journal_title：Fitoterapia

authors： Okunade AL,Lewis WH,Elvin-Lewis MP,Casper SJ,Goldberg DE

更新日期：2001-08-01 00:00:00

abstract：:Two new neo-clerodane diterpenoids have been isolated from the whole plant of Scutellaria barbata D. Don, and their structures were established by detailed spectral analyses as scutehenanine H (1) and 6-(2,3-epoxy-2-isopropyl-n-propoxyl)barbatin C (2). In vitro, the isolated two new compounds showed significant cytoto...

journal_title：Fitoterapia

authors： Dai SJ,Qu GW,Yu QY,Zhang DW,Li GS

更新日期：2010-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is highly prevalent among global populations, with an estimated number of infected patients being 170 million. Approximately 70-80% of patients acutely infected with HCV will progress to chronic liver disease, such as liver cirrhosis and hepatocellular carcinoma, which is a substantia...

journal_title：Fitoterapia

authors： Wahyuni TS,Widyawaruyanti A,Lusida MI,Fuad A,Soetjipto,Fuchino H,Kawahara N,Hayashi Y,Aoki C,Hotta H

更新日期：2014-12-01 00:00:00

abstract：:The aim of the present research was to establish a comprehensive strategy to identify the metabolites of isoimperatorin after biotransformation with rat liver microsomes in vitro, and further describe metabolic kinetic characteristics of isoimperatorin and its main metabolites. Utilizing liquid chromatography with tim...

journal_title：Fitoterapia

authors： Chen TL,Zhang YB,Xu W,Kang TG,Yang XW

更新日期：2014-03-01 00:00:00

abstract：:A different type of biologically active compound from Kuji amber (Late Cretaceous, Japan) before the K-Pg boundary [65 million years ago (Ma)] was isolated based on the growth-restoring activity of a mutant yeast involving Ca2+ signal transduction. It was identified as a spirolactone norditerpenoid, (4R*, 5S*, 8R*, 9R...

journal_title：Fitoterapia

authors： Shimizu E,Koshino H,Noro A,Maruyama M,Shimoda N,Uesugi S,Ohnishi M,Kimura KI

更新日期：2019-04-01 00:00:00

abstract：:Combinations of thyme, cowslip and liquorice roots are often used in the treatment of upper respiratory tract infections. Therefore the volatile fraction of herbal teas prepared from thyme (Thymus vulgaris) and the effect of combining with cowslip (Primula veris/P. elatior) and liquorice roots (Glycyrrhiza glabra) on ...

journal_title：Fitoterapia

authors： Tschiggerl C,Bucar F

更新日期：2011-09-01 00:00:00

abstract：:With the goal of unravelling antimicrobial agents and mixtures inspired by plant defences, we investigated the antibacterial and antifungal efficacy of Hirtellina lobelii DC. essential oil (EO), both alone and in combination with antimicrobial drugs. Hirtellina lobelii DC. EO was analysed by GC, GC-MS and partial frac...

journal_title：Fitoterapia

authors： Khoury M,El Beyrouthy M,Ouaini N,Eparvier V,Stien D

更新日期：2019-03-01 00:00:00

abstract：:The aqueous extract of Crinum giganteum given intraperitoneally at doses of 6.25, 12.5 and 25 mg/kg in rats prolonged the duration of pentobarbital sleeping time and in mice reduced spontaneous motor activity, decreased the exploratory activity and attenuated amphetamine-induced stereotype behavior. The intraperitonea...

journal_title：Fitoterapia

authors： Amos S,Binda L,Akah P,Wambebe C,Gamaniel K

更新日期：2003-02-01 00:00:00

abstract：:Extracts of roots of Rumex nepalensis, Berberis aristata, Arnebia benthamii, bark of Taxus wallichiana, Juglans regia and petals of Jacquinia ruscifolia were tested for their antifungal activity against twelve different fungal pathogens. Ethanolic extracts of R. nepalensis and J. ruscifolia extracts showed a broad spe...

journal_title：Fitoterapia

authors： Sharma RS,Mishra V,Singh R,Seth N,Babu CR

更新日期：2008-12-01 00:00:00

abstract：:An endophytic fungal strain named Trichoderma atroviride was isolated from the bulb of Lycoris radiata. Following cultivation on rice medium, a novel 3-amino-5-hydroxy-5-vinyl-2-cyclopenten-1-one dimer, atrichodermone A (1), a new cyclopentenone derivative, atrichodermone B (2), and a new sesquiterpene, atrichodermone...

journal_title：Fitoterapia

authors： Zhou P,Wu Z,Tan D,Yang J,Zhou Q,Zeng F,Zhang M,Bie Q,Chen C,Xue Y,Luo Z,Wang J,Zhu H,Zhang Y

更新日期：2017-11-01 00:00:00

abstract：:Investigators and sponsors of dietary supplement research need to know the relevant regulatory requirements and how to comply with them. This brief review describes how research on dietary supplements is regulated by FDA. In general, whether an FDA sanctioned Investigational New Drug (IND) application is required for ...

journal_title：Fitoterapia

authors： Chen ST

更新日期：2011-01-01 00:00:00

abstract：:The present study was designed to verify whether frutalin (FTL) affords gastroprotection against the ethanol-induced gastric damage and to examine the underlying mechanism(s). Gastric damage was induced by intragastric administration of 0.2 ml of ethanol (96%). Mice in groups were pretreated with FTL (0.25, 0.5 and 1 ...

journal_title：Fitoterapia

authors： de Vasconcellos Abdon AP,Coelho de Souza G,Noronha Coelho de Souza L,Prado Vasconcelos R,Araújo Castro C,Moreira Guedes M,Pereira Lima RC Jr,de Azevedo Moreira R,de Oliveira Monteiro-Moreira AC,Rolim Campos A

更新日期：2012-04-01 00:00:00

abstract：:alpha(2)beta(1) and alpha(IIb)beta(3) integrins, that support platelet adhesion to collagen and fibrinogen, respectively, share common signaling molecules. The effect of quercetin on platelet static adhesion to collagen and fibrinogen was assessed and correlated with its kinase inhibitory activity. Quercetin strongly ...

journal_title：Fitoterapia

authors： Navarro-Núñez L,Lozano ML,Martínez C,Vicente V,Rivera J

更新日期：2010-03-01 00:00:00

abstract：:The methanol extract of the bark of Litsea glutinosa showed antibacterial activity, comparable to chloramphenicol, against all 16 tested microorganisms. ...

journal_title：Fitoterapia

authors： Mandal SC,Kumar CK,Majumder A,Majumder R,Maity BC

更新日期：2000-08-01 00:00:00