Steroidal esters from Ferula sinkiangensis.

Abstract:

:Two new steroidal esters with an unusual framework, Sinkiangenorin A and B, a new organic acid glycoside, Sinkiangenorin C, and four known lignin compounds were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds were established by spectroscopic analysis and single-crystal X-ray diffraction. All of the isolated compounds were tested against Hela, K562 and AGS human cancer cell lines. Sinkiangenorin C showed cytotoxic activity against AGS cells with an IC50 of 36.9 μM.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Li G,Li X,Cao L,Shen L,Zhu J,Zhang J,Wang J,Zhang L,Si J

doi

10.1016/j.fitote.2014.06.016

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

247-52

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(14)00180-4

journal_volume

97

pub_type

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